The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 1,786,846 18,080 SH SOLE 18,080 0 0
ABBVIE INC COM 00287Y109 3,217,557 12,300 SH SOLE 12,300 0 0
ABIVAX SA SPONSORED ADS 00370M103 1,441,830 14,561 SH SOLE 14,561 0 0
ALNYLAM PHARMACUETCL COM 02043Q107 1,822,175 7,385 SH SOLE 7,385 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 2,540,268 246,150 SH SOLE 70,250 0 175,900
ALX ONCOLOGY HLDGS INC COM 00166B105 125,100 90,000 SH SOLE 90,000 0 0
AMGEN INC COM 031162100 3,313,069 7,860 SH SOLE 7,860 0 0
APNIMED INC COM 03770Y107 20,643,777 942,208 SH SOLE 942,208 0 0
ARCUS BIOSCIENCES COM 03969F109 2,994,549 115,933 SH SOLE 46,433 0 69,500
ARDELYX INC COM 039697107 191,862 56,100 SH SOLE 56,100 0 0
ARGENX SE SP ADR 04016X101 2,566,043 2,676 SH SOLE 2,676 0 0
ARRIVENT BIOPHARMA COM 04272N102 2,644,746 87,343 SH SOLE 28,013 0 59,330
ARS PHARMACEUTICALS COM 82835W108 173,693 40,300 SH SOLE 40,300 0 0
ASCENDIS PHARMA A/S ORD SHS K08588103 585,523 2,570 SH SOLE 2,570 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306 2,717,917 177,294 SH SOLE 57,700 0 119,594
AXSOME THERAPEUTIC COM 05464T104 276,585 1,500 SH SOLE 1,500 0 0
BIOGEN INC COM 09062X103 417,878 1,850 SH SOLE 1,850 0 0
BIOMARIN PHARMAC COM 09061G101 567,000 9,450 SH SOLE 9,450 0 0
BIONTECH SE SP ADR 09075V102 2,967,186 30,185 SH SOLE 12,680 0 17,505
BOSTON SCIENTIFIC COM 101137107 642,965 14,730 SH SOLE 14,730 0 0
BRAVEHEART BIO INC COM SHS 10567X101 2,418,809 119,743 SH SOLE 35,691 0 84,052
BRISTOL MYERS SQUIBB COM 110122108 752,606 12,061 SH SOLE 12,061 0 0
CENTENE CORP DEL COM 15135B101 747,925 12,040 SH SOLE 12,040 0 0
CONTINEUM THERAPEUTICS CL A 21217B100 9,254,258 689,587 SH SOLE 689,587 0 0
CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301 190,960 28,000 SH SOLE 28,000 0 0
CRESCENT BIOPHARMA INC. COM G2545C104 2,445,284 167,600 SH SOLE 56,000 0 111,600
CVS HEALTH CORP COM 126650100 1,117,483 13,041 SH SOLE 13,041 0 0
CYTOKINETICS INC COM NEW 23282W605 1,007,698 15,289 SH SOLE 15,289 0 0
DANAHER CORP COM 235851102 2,128,905 9,597 SH SOLE 9,597 0 0
DEXCOM INC COM 252131107 3,212,663 37,231 SH SOLE 17,381 0 19,850
EDWARDS LIFESCIENCES COM 28176E108 587,321 6,804 SH SOLE 6,804 0 0
ELEVANCE HEALTH INC COM 036752103 779,973 2,006 SH SOLE 2,006 0 0
ELI LILLY & CO COM 532457108 7,710,781 6,664 SH SOLE 6,664 0 0
ENGENE THERAPEUTICS INC COM 29286X101 43,400 21,700 SH SOLE 21,700 0 0
EYEPOINT INC COM NEW 30233G209 77,499 23,700 SH SOLE 23,700 0 0
GENMAB A/S SPONSORED ADS 372303206 353,183 9,900 SH SOLE 9,900 0 0
GILEAD SCIENCES INC COM 375558103 3,674,828 24,655 SH SOLE 24,655 0 0
GUARDANT HEALTH INC COM 40131M109 353,153 1,980 SH SOLE 1,980 0 0
HUMANA INC INC 444859102 478,870 1,255 SH SOLE 1,255 0 0
ILLUMINA INC COM 452327109 583,486 2,132 SH SOLE 2,132 0 0
IMMATICS NV SHS N44445109 1,984,148 225,985 SH SOLE 26,887 0 199,098
INCYTE CORPORATION COM 45337C102 285,173 2,350 SH SOLE 2,350 0 0
INSMED INC COM PAR $.01 457669307 2,705,803 23,706 SH SOLE 23,706 0 0
INTUITIVE SURGIC INC COM NEW 46120E602 2,386,511 5,869 SH SOLE 5,869 0 0
IONIS PHARMACEUTICAL COM 462222100 321,480 7,200 SH SOLE 7,200 0 0
IQVIA HOLDINGS INC COM 46266C105 1,885,714 7,014 SH SOLE 7,014 0 0
IRHYTHM HOLDINGS INC COM 450056106 2,565,306 22,570 SH SOLE 6,660 0 15,910
JOHNSON & JOHNSON COM 478160104 6,024,953 22,758 SH SOLE 22,758 0 0
KURA ONCOLOGY INC COM 50127T109 182,606 17,050 SH SOLE 17,050 0 0
MEDTRONIC PLC SHS G5960L103 965,811 11,100 SH SOLE 11,100 0 0
MERCK & CO INC COM 58933Y105 2,985,210 20,460 SH SOLE 20,460 0 0
MODERNA INC COM 60770K107 1,020,621 5,300 SH SOLE 5,300 0 0
NEKTAR THERAPEUTICS COM NEW 640268306 612,171 10,111 SH SOLE 10,111 0 0
NEUROCRINE BIOSCIENCES COM 64125C109 163,116 1,150 SH SOLE 1,150 0 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109 231,040 9,500 SH SOLE 9,500 0 0
ORIC PHARMACEUTICALS COM 68622P109 316,545 23,500 SH SOLE 23,500 0 0
ORUKA THERAPEUTICS INC COM 687604108 2,944,218 35,349 SH SOLE 14,689 0 20,660
PALISADE BIO INC COM 696389402 118,800 88,000 SH SOLE 88,000 0 0
PFIZER INC COM 717081103 1,639,900 57,500 SH SOLE 57,500 0 0
PTC THERAPEUTICS INC COM 69366J200 555,165 8,570 SH SOLE 8,570 0 0
PULSE BIOSCIENCES INC COM 74587B101 1,306,406 26,170 SH SOLE 0 0 26,170
REGENERON PHARMCTCLS COM 75886F107 2,175,477 2,869 SH SOLE 2,869 0 0
REVOLUTION MEDICINES COM 76155X100 566,518 2,760 SH SOLE 2,760 0 0
ROIVANT SCIENCES LTD SHS G76279101 2,124,717 58,100 SH SOLE 58,100 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 420,192 7,200 SH SOLE 7,200 0 0
SHOULDER INNOVATIONS COMMON STOCK 82537J108 8,134,938 430,420 SH SOLE 430,420 0 0
STRYKER CORP COM 863667101 2,160,859 7,829 SH SOLE 7,829 0 0
SUMMIT THERAPEUTICS COM 86627T108 2,996,114 177,180 SH SOLE 80,805 0 96,375
TANGO THERAPEUTICS INC COM 87583X109 2,638,637 105,757 SH SOLE 39,757 0 66,000
TECTONIC THERAPEUTIC COM 878972108 1,690,668 72,592 SH SOLE 18,592 0 54,000
TEMPUS AI INC CL A 88023B103 317,772 3,880 SH SOLE 3,880 0 0
THERMO FISHER SCIENTIFIC COM 883556102 1,964,203 2,908 SH SOLE 2,908 0 0
TRANSMEDICS GROUP INC COM 89377M109 1,331,028 15,950 SH SOLE 0 0 15,950
UNIQURE N.V. SHS N90064101 1,508,188 62,425 SH SOLE 27,425 0 35,000
UNITED THERAPEUTICS COM 91307C102 1,460,394 2,695 SH SOLE 2,695 0 0
UNITEDHEALTH GRP INC COM 91324P102 2,278,833 6,208 SH SOLE 6,208 0 0
VERA THERAPEUTICS CL A 92337R101 922,622 28,573 SH SOLE 28,573 0 0
VERTEX PHARMA COM 92532F100 3,937,805 7,532 SH SOLE 7,532 0 0