| Segment Information |
Segment Information The Company is operated and managed as a single operating and reportable segment which focuses on the discovery, development and commercialization of medicines and technologies. The Company’s Chief Operating Decision Maker (“CODM”) is its chief executive officer. The CODM assesses performance for the Company based on net loss, which is reported on the condensed consolidated statements of operations and comprehensive loss as net loss. The measure of segment assets is reported on the condensed consolidated balance sheets as total assets. The Company expects to continue to incur significant expenses and operating losses for the foreseeable future as it advances product candidates through all stages of development and clinical trials and, ultimately, seeks regulatory approval. As such, the CODM uses cash forecast models and budgeted versus actual results to assess performance, make operating decisions and allocate resources across the Company including to various Vants and research and development projects. The Company’s significant segment expenses are as follows (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Six Months Ended September 30, | | 2026 | | 2025 | | 2026 | | 2025 | | Product revenue, net | $ | 30,969 | | | $ | — | | | $ | 30,969 | | | $ | — | | | License, milestone and other revenue | 4,152 | | | 1,571 | | | 5,594 | | | 3,741 | | | Less: | | | | | | | | | Cost of revenues | 3,347 | | | 111 | | | 3,631 | | | 265 | | | Program-specific research and development expenses: | | | | | | | | | Anti-FcRn franchise—endocrine diseases | 22,461 | | | 24,895 | | | 65,346 | | | 44,224 | | | Anti-FcRn franchise—neurological diseases | 18,274 | | | 23,087 | | | 43,729 | | | 44,024 | | | Anti-FcRn franchise—rheumatology diseases | 9,864 | | | 13,611 | | | 32,204 | | | 21,820 | | | Anti-FcRn franchise—dermatology diseases | 648 | | | 7,952 | | | 8,190 | | | 13,097 | | | Anti-FcRn franchise—other clinical and nonclinical | 268 | | | 319 | | | 2,877 | | | 2,711 | | | Brepocitinib | 14,436 | | | 14,715 | | | 28,528 | | | 29,735 | | | Mosliciguat | 19,051 | | | 7,467 | | | 32,092 | | | 15,852 | | | Other development and discovery programs | 11,815 | | | 11,184 | | | 22,933 | | | 21,420 | | | Research and development share-based compensation | 7,965 | | | 10,996 | | | 16,686 | | | 22,095 | | | Research and development personnel-related expenses | 33,267 | | | 40,658 | | | 79,621 | | | 83,188 | | | Other research and development expenses | 7,698 | | | 9,684 | | | 15,557 | | | 19,321 | | | Selling, general and administrative share-based compensation | 71,332 | | | 70,825 | | | 145,953 | | | 141,904 | | | Selling, general and administrative personnel-related expenses | 38,792 | | | 37,951 | | | 94,992 | | | 68,061 | | | Other selling, general and administrative expenses | 43,952 | | | 34,349 | | | 78,658 | | | 67,179 | | | Gain on litigation settlement | — | | | — | | | (392) | | | — | | | Change in fair value of investments | (60,292) | | | (128,501) | | | (96,929) | | | (109,376) | | | Change in fair value of liability instruments | — | | | 20,959 | | | — | | | 23,288 | | | Interest income | (41,612) | | | (45,341) | | | (78,534) | | | (93,663) | | | Other expense, net | 200 | | | 5,694 | | | 2,330 | | | 16,902 | | | Income tax (benefit) expense | (13,371) | | | 6,995 | | | (17,329) | | | 11,644 | | | Income from discontinued operations, net of tax | (15,763) | | | — | | | (15,763) | | | — | | | Net loss | $ | (137,211) | | | $ | (166,039) | | | $ | (427,817) | | | $ | (439,950) | |
|