| Summary of the Significant Segment Expenses |
A summary of the significant segment expenses reported to the CODM are shown below for the three and nine months ended September 30, 2026 and 2025:
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Three Months Ended September 30, |
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|
Nine Months Ended September 30, |
|
(in thousands) |
|
2026 |
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|
2025 |
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|
2026 |
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|
2025 |
|
Operating Expenses |
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|
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|
|
|
Z-rostudirsen (DMD) |
|
$ |
66,877 |
|
|
$ |
22,666 |
|
|
$ |
156,946 |
|
|
$ |
73,314 |
|
Z-basivarsen (DM1) |
|
|
32,816 |
|
|
|
37,853 |
|
|
|
96,577 |
|
|
|
117,964 |
|
Platform and external research and development |
|
|
21,464 |
|
|
|
5,769 |
|
|
|
47,046 |
|
|
|
21,399 |
|
Personnel related |
|
|
32,266 |
|
|
|
22,517 |
|
|
|
89,613 |
|
|
|
62,730 |
|
Stock-based compensation |
|
|
16,206 |
|
|
|
11,082 |
|
|
|
44,263 |
|
|
|
34,625 |
|
Facility-related and other |
|
|
14,836 |
|
|
|
9,448 |
|
|
|
39,225 |
|
|
|
26,703 |
|
Professional and consulting fees |
|
|
12,609 |
|
|
|
4,557 |
|
|
|
30,341 |
|
|
|
15,320 |
|
Interest income |
|
|
(9,767 |
) |
|
|
(8,476 |
) |
|
|
(26,312 |
) |
|
|
(22,202 |
) |
Interest expense |
|
|
5,949 |
|
|
|
2,904 |
|
|
|
14,746 |
|
|
|
2,998 |
|
Other expense (income), net |
|
|
296 |
|
|
|
(279 |
) |
|
|
517 |
|
|
|
1,408 |
|
Net loss |
|
$ |
193,552 |
|
|
$ |
108,041 |
|
|
$ |
492,962 |
|
|
$ |
334,259 |
|
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