v3.26.3
Segment Reprting
9 Months Ended
Sep. 30, 2026
Segment Reporting [Abstract]  
Segment Reporting

9. Segment Reporting

The Company’s segment determination is based on the financial results that are regularly evaluated by the Company’s chief operating decision maker ("CODM") to determine resource allocation and assess performance. The Company's CODM is its chief executive officer. The Company has one operating and one reportable segment. Net long-lived assets are all physically located in the United States and the total assets of the segment equal the total assets presented on the condensed consolidated balance sheet. The primary financial measure by which the CODM evaluates the business is net loss. The CODM uses net loss to monitor budget versus actual results to assess performance of the segment. A summary of the significant segment expenses reported to the CODM are shown below for the three and nine months ended September 30, 2026 and 2025:

 

 

 

Three Months Ended September 30,

 

 

Nine Months Ended September 30,

 

(in thousands)

 

2026

 

 

2025

 

 

2026

 

 

2025

 

Operating Expenses

 

 

 

 

 

 

 

 

 

 

 

 

Z-rostudirsen (DMD)

 

$

66,877

 

 

$

22,666

 

 

$

156,946

 

 

$

73,314

 

Z-basivarsen (DM1)

 

 

32,816

 

 

 

37,853

 

 

 

96,577

 

 

 

117,964

 

Platform and external research and development

 

 

21,464

 

 

 

5,769

 

 

 

47,046

 

 

 

21,399

 

Personnel related

 

 

32,266

 

 

 

22,517

 

 

 

89,613

 

 

 

62,730

 

Stock-based compensation

 

 

16,206

 

 

 

11,082

 

 

 

44,263

 

 

 

34,625

 

Facility-related and other

 

 

14,836

 

 

 

9,448

 

 

 

39,225

 

 

 

26,703

 

Professional and consulting fees

 

 

12,609

 

 

 

4,557

 

 

 

30,341

 

 

 

15,320

 

Interest income

 

 

(9,767

)

 

 

(8,476

)

 

 

(26,312

)

 

 

(22,202

)

Interest expense

 

 

5,949

 

 

 

2,904

 

 

 

14,746

 

 

 

2,998

 

Other expense (income), net

 

 

296

 

 

 

(279

)

 

 

517

 

 

 

1,408

 

Net loss

 

$

193,552

 

 

$

108,041

 

 

$

492,962

 

 

$

334,259