v3.26.3
SEGMENT INFORMATION
 9 Months Ended
Sep. 30, 2026
Segment Reporting [Abstract]  
SEGMENT INFORMATION SEGMENT INFORMATION
The Company operates and manages its business as one reportable operating segment. The Company's chief operating decision maker (“CODM”) is the chief executive officer. The CODM reviews financial information on an aggregate basis for the purposes of evaluating financial performance and allocating resources based on net income (loss), adjusted gross profit, adjusted gross margin and adjusted EBITDA. Net income (loss) is the measure of segment profit most consistent with U.S. GAAP that is regularly reviewed by the CODM to allocate resources and assess performance. The CODM does not evaluate operating segment performance using asset information.

Effective June 1, 2026, Dr. Joshua Ofman was appointed chief executive officer and became the Company’s CODM. Following this leadership transition, the Company revised the internal management reporting package provided to the CODM, including changes to the presentation and composition of segment expenses, to align with how the CODM manages operations, assesses performance, allocates resources, and develops strategic priorities. As a result, the Company updated its segment reporting structure and has revised the presentation of segment information for the nine months ended September 30, 2026, and three and nine months ended September 30, 2025, to conform to the current-period presentation. The Company continues to operate and manage its business as one reportable segment and the revised presentation does not change total revenue, total costs and operating expenses, loss from operations, or net loss for any period presented.
The following table includes the significant expense categories regularly provided to the CODM when managing the Company’s single reporting segment. A reconciliation to the consolidated net loss for the three and nine months ended September 30, 2026 and September 30, 2025 is included in the table below:

Three Months Ended
Nine Months Ended
(in thousands)September 30,
2026		September 30,
2025		September 30,
2026		September 30,
2025
Revenue:
Screening revenue$37,269 $32,807 $119,743 $96,319 
Development services revenue266 3,387 3,264 7,256 
Total revenue37,535 36,194 123,007 103,575 
Costs and operating expenses:
Cost of screening revenue (exclusive of amortization of intangible assets) (1)
22,032 15,910 66,623 52,379 
Cost of development services revenue (1)
141 544 951 2,216 
Research and development38,991 43,156 123,940 133,765 
Sales and marketing37,241 21,894 96,893 77,388 
General and administrative33,324 28,468 103,565 91,935 
Depreciation and intangible assets amortization36,868 37,645 111,054 112,576 
Stock-based compensation13,557 13,868 48,725 43,068 
Intangible and other assets impairment— — 25,423 28,000 
Total costs and operating expenses182,154 161,485 577,174 541,327 
Loss from operations(144,619)(125,291)(454,167)(437,752)
Other income (expense):
Interest income7,843 6,107 23,059 20,695 
Other income (expense), net(545)466 (444)(929)
Benefit from income taxes33,753 29,741 124,550 108,811 
Net loss$(103,568)$(88,977)$(307,002)$(309,175)
(1) Cost of screening revenue (exclusive of amortization of intangible assets) and cost of development services revenue include stock-based compensation expense of $0.6 million and $1.7 million for the three and nine months ended September 30, 2026 and $0.3 million and $1.5 million for the three and nine months ended September 30, 2025.