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[Table] Common Stock Common Stock [Member] Total marketable securities Fair Value Debt Securities, Available-for-Sale Market-based stock units Market-Based Stock Units [Member] Market-Based Stock Units Operating lease costs Operating Lease, Cost Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Cover [Abstract] Rest of world Non-US [Member] Milestone payment for achievement of specified ex-U.S. commercial milestone event Portion Of Potential Milestone Payment Receivable For Filing Of New Drug Application Portion Of Potential Milestone Payment Receivable For Filing Of New Drug Application Expired (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expired in Period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expired in Period Equity Awards Adjustments Equity Awards Adjustments [Member] Security deposit liability Security Deposit Liability Realized gain (loss) on marketable securities Debt Securities, Available-for-Sale, Realized Gain (Loss) Total liabilities and stockholders’ equity Liabilities and Equity Returns/ replacement/ other, payments/returns relating to sales in the current year Contract With Customer Right To Recover Product, Current Year Recoveries Realized gain on investments Realized Investment Gains (Losses) Stock options Share-Based Payment Arrangement, Option [Member] Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Schedule of Future Minimum Lease Payments to be Received under the Long-term Sublease Agreements Lessor, Operating Lease, Payment to be Received, Maturity [Table Text Block] Segments [Axis] Segments [Axis] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Plan Name [Axis] Plan Name [Axis] Schedule of Product Revenue Allowance and Reserve Schedule of Accounts, Notes, 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Options, Vested in Period, Weighted Average Grant Date Fair Value Deductions Contract with Customer, Receivable, after Allowance for Credit Loss, Proceeds From Collection Of Receivables Contract with Customer, Receivable, after Allowance for Credit Loss, Proceeds From Collection Of Receivables Cost of sales Cost of Product and Service Sold Award Timing Method Award Timing Method [Text Block] Net change in cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Total, payments/returns relating to sales in the current year Contract With Customer, Current Year Reserve Recoveries Returns/ Replacement/ Other Product Returns [Roll Forward] 2028 Lessor, Operating Lease, Payment to be Received, Year Two Net loss Net loss Net loss Net loss Net Income (Loss) Attributable to Parent Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Balance Sheet Location [Axis] Location, Statement of Financial Position, Balance [Axis] Statement [Table] Statement [Table] Share-Based Payment Arrangement, Tranche Two Share-Based Payment Arrangement, Tranche Two [Member] Restatement Determination Date: Restatement Determination Date [Axis] Certificates of deposit Certificates of Deposit [Member] Exercisable (in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]