Convertible Preferred Stock and Stockholders' Equity (Additional information) (Details) - USD ($)
$ / shares in Units, $ in Thousands |
1 Months Ended |
3 Months Ended |
9 Months Ended |
12 Months Ended |
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Mar. 31, 2024 |
Apr. 30, 2023 |
Jan. 31, 2021 |
Nov. 30, 2016 |
Sep. 30, 2026 |
Sep. 30, 2026 |
Sep. 30, 2025 |
Dec. 31, 2024 |
Nov. 05, 2026 |
Dec. 31, 2025 |
Aug. 31, 2025 |
Nov. 30, 2023 |
May 02, 2017 |
| Convertible preferred stock |
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| Preferred stock, par value (in dollars per share) |
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$ 0.001
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$ 0.001
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$ 0.001
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| Exercise price of warrants |
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$ 100
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| Common Stock, Shares, Issued |
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121,533,910
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121,533,910
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115,359,735
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| Issuance of common stock from ATM offering, net of commissions and issuance costs |
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$ 7,598
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$ 7,598
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$ 0
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| Net proceeds |
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7,600
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| Employee And Non Employee Stock Option |
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| Convertible preferred stock |
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| Unrecognized compensation cost related to outstanding options |
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5,600
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$ 5,600
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| Expected recognition weighted average period of unrecognized compensation cost |
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1 year 9 months 18 days
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| Restricted Stock Units (RSUs) |
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| Convertible preferred stock |
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| Expected recognition weighted average period of unrecognized compensation cost |
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2 years 4 months 24 days
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| Unrecognized compensation cost related to unvested restricted shares |
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$ 7,000
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$ 7,000
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| Pre-Funded Warrants |
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| Convertible preferred stock |
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| Number of shares to be purchased |
3,636,364
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257,310
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3,893,674
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3,893,674
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| Purchase price of prefunded warrants |
$ 5.499
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$ 85.499
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| Exercise price of warrants |
$ 0.001
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$ 0.001
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| Terms of exercise |
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The Pre-Funded Warrants are exercisable at any time after the date of issuance. A holder of Pre-Funded Warrants may not exercise the Pre-Funded Warrant if the holder, together with its affiliates, would beneficially own more than 9.99% of the number of shares of the Company’s common stock outstanding immediately after giving effect to such exercise. A holder of Pre-Funded Warrants may increase or decrease this percentage not in excess of 19.99% by providing at least 61 days’ prior notice to the Company.
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| Maximum percentage of common stock ownership together with affiliates allowable after exercise of prefunded warrants |
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9.99%
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9.99%
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| Maximum percentage of common stock ownership after change upon notice |
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19.99%
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19.99%
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| At The Market Offering [Member] |
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| Convertible preferred stock |
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| Public offering of common stock, net of issuance costs (in shares) |
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2,801,602
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| Issuance of common stock from ATM offering, net of commissions and issuance costs |
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$ 8,000
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| Leerink Partners LLC [Member] | At The Market Offering [Member] |
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| Convertible preferred stock |
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| Common Stock, Shares, Issued |
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100,000,000
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| Minimum | Redmile Group, LLC and Affiliates |
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| Convertible preferred stock |
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| Percentage of common stock ownership upon preferred stock conversion |
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9.99%
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| Maximum | Redmile Group, LLC and Affiliates |
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| Convertible preferred stock |
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| Percentage of common stock ownership upon preferred stock conversion |
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14.99%
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| Common Stock |
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| Convertible preferred stock |
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| Public offering of common stock, net of issuance costs (in shares) |
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2,801,602
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| Conversion of preferred shares to common stock |
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167,205
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30,110
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| Issuance of common stock from ATM offering, net of commissions and issuance costs |
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$ 3
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| Non-Voting Class A Preferred Stock | Redmile Group, LLC and Affiliates |
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| Convertible preferred stock |
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| Percentage of common stock ownership upon preferred stock conversion |
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19.99%
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| Terms of conversion |
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The Class A Preferred were purchased exclusively by entities affiliated with Redmile Group, LLC (collectively, Redmile). The terms of the CoD prohibited Redmile from converting the Class A Preferred into shares of the Company’s common stock if, as a result of conversion, Redmile, together with its affiliates, would own more than 9.99% of the Company’s common stock then issued and outstanding (the Redmile Percentage Limitation), which percentage could change at Redmile’s election upon 61 days’ notice to the Company to (i) any other number less than or equal to 19.99% or (ii) subject to approval of the Company’s stockholders to the extent required in accordance with the Nasdaq Global Market rules, any number in excess of 19.99%. On May 2, 2017, the Company’s stockholders approved the issuance of up to an aggregate of 14,097,745 shares of common stock upon the conversion of the outstanding shares of Class A Preferred. As a result, Redmile has the right to increase the Redmile Percentage Limitation to any percentage in excess of 19.99% at its election.
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| Non-Voting Class A Preferred Stock | Maximum |
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| Convertible preferred stock |
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| Number of shares to be issued upon conversion |
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14,097,745
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| Non-Voting Class A Preferred Stock | Maximum | Redmile Group, LLC and Affiliates |
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| Convertible preferred stock |
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| Percentage of common stock ownership upon preferred stock conversion |
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9.99%
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| Preferred shares converted into common stock percentage of ownership change upon notice |
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19.99%
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| Convertible Preferred Stock |
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| Convertible preferred stock |
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| Preferred stock, issued shares |
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2,755,086
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2,755,086
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2,755,086
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| Percentage of common stock ownership upon preferred stock conversion |
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14.99%
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| Conversion of preferred shares to common stock |
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33,441
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6,022
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| Convertible Preferred Stock | Redmile Group, LLC and Affiliates |
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| Convertible preferred stock |
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| Percentage of common stock ownership upon preferred stock conversion |
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19.99%
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| November 2016 Placement | Common Stock |
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| Convertible preferred stock |
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| Share issue price (in dollars per share) |
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$ 2.66
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| Public offering of common stock, net of issuance costs (in shares) |
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7,236,837
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| November 2016 Placement | Non-Voting Class A Preferred Stock |
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| Convertible preferred stock |
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| Preferred stock, issued shares |
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2,819,549
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| Share issue price (in dollars per share) |
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$ 13.3
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| Preferred stock, par value (in dollars per share) |
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0.001
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| Conversion price |
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$ 2.66
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