| Schedule of Segment Reporting |
The following table sets forth information about the Company’s single reportable segment and the significant expenses reviewed by the CODM, including a reconciliation to net loss (in thousands): | | | | | | | | | | | | | Three Months Ended September 30, | | 2026 | | 2025 | | Revenue | $ | — | | | $ | 1,000 | | | Operating expenses: | | | | | Research and development: | | | | | SL-325 | 8,972 | | | 2,455 | | SL-8461 | 5,175 | | | — | | Other research and development2 | 3,470 | | | 2,266 | | | Research and development non-equity compensation | 2,707 | | | 2,229 | | | Research and development equity compensation | 1,242 | | | 668 | | | Total research and development | 21,566 | | | 7,618 | | | General and administrative expenses: | | | | | General and administrative non-equity compensation | 1,413 | | | 1,288 | | | General and administrative equity compensation | 2,057 | | | 1,109 | | | Other general and administrative including legal and accounting fees, facilities, insurance, travel and depreciation | 2,010 | | | 1,701 | | | Total general and administrative | 5,480 | | | 4,098 | | | Expense from operations | 27,046 | | | 11,716 | | | Loss from operations | (27,046) | | | (10,716) | | Other income | 1,843 | | | 660 | | Net loss | $ | (25,203) | | | $ | (10,056) | |
1 Expenses for SL-846 that were incurred prior to nomination as a product candidate are included in “other research and development.” 2 Other research and development expense includes technical operations expense of $2.0 million and $0.6 million, research activities for other pipeline compounds and facility expenses of $0.7 million and $0.8 million, and depreciation expense of $0.8 million and $0.9 million for the three months ended September 30, 2026 and 2025, respectively. The following table sets forth information about the Company’s single reportable segment and the significant expenses reviewed by the CODM, including a reconciliation to net loss (in thousands): | | | | | | | | | | | | | Nine Months Ended September 30, | | 2026 | | 2025 | | Revenue | $ | — | | | $ | 1,000 | | | Operating expenses: | | | | | Research and development: | | | | | SL-325 | 17,639 | | | 7,289 | | SL-8461 | 7,388 | | | — | | Other research and development2 | 8,383 | | | 9,751 | | | Research and development non-equity compensation | 7,450 | | | 6,955 | | | Research and development equity compensation | 3,353 | | | 2,223 | | | Total research and development | 44,213 | | | 26,218 | | | General and administrative expenses: | | | | | General and administrative non-equity compensation | 4,235 | | | 4,005 | | | General and administrative equity compensation | 5,094 | | | 3,166 | | | Other general and administrative including legal and accounting fees, facilities, insurance, travel and depreciation | 5,204 | | | 5,748 | | | Total general and administrative | 14,533 | | | 12,919 | | | Expense from operations | 58,746 | | | 39,137 | | | Loss from operations | (58,746) | | | (38,137) | | Other income | 3,623 | | | 1,921 | | Net loss | $ | (55,123) | | | $ | (36,216) | |
1 Expenses for SL-846 that were incurred prior to nomination as a product candidate are included in “other research and development.” 2 Other research and development expense includes technical operations expense of $4.7 million and $1.7 million, research activities for other pipeline compounds and facility expenses of $1.3 million and $2.8 million, and depreciation expense of $2.4 million and $2.7 million for the nine months ended September 30, 2026 and 2025, respectively.
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