v3.26.3
Segment Information - Schedule of Significant Segment Expense Categories (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2026
Jun. 30, 2026
Mar. 31, 2026
Sep. 30, 2025
Jun. 30, 2025
Mar. 31, 2025
Sep. 30, 2026
Sep. 30, 2025
Segment Reporting [Line Items]                
Research and development expense $ (44,080)     $ (50,334)     $ (136,917) $ (124,416)
Stock-based compensation expense (14,605)     (9,514)     (40,499) (24,297)
Net loss (59,535) $ (59,532) $ (63,504) (62,321) $ (55,247) $ (34,085) (182,571) (151,653)
Significant Segment Expense Category [Member]                
Segment Reporting [Line Items]                
Commercial expense (4,117)     (3,928)     (15,634) (8,509)
General and administrative expense (8,654)     (8,343)     (25,791) (23,074)
Stock-based compensation expense (14,605)     (9,514)     (40,499) (24,297)
Other Segment Items [Member]                
Segment Reporting [Line Items]                
Other segment items 4,626     5,375     16,189 17,399
Key Measure of Segment Profit or Loss [Member]                
Segment Reporting [Line Items]                
Net loss (59,535)     (62,321)     (182,571) (151,653)
Bitopertin [Member] | Significant Segment Expense Category [Member]                
Segment Reporting [Line Items]                
Research and development expense (6,992)     (11,833)     (24,998) (43,954)
Selcodebart [Member] | Significant Segment Expense Category [Member]                
Segment Reporting [Line Items]                
Research and development expense (8,422)     (7,369)     (28,885) (18,105)
DISC-3405 [Member] | Significant Segment Expense Category [Member]                
Segment Reporting [Line Items]                
Research and development expense (4,880)     (11,910)     (19,027) (15,486)
Other Research [Member] | Significant Segment Expense Category [Member]                
Segment Reporting [Line Items]                
Research and development expense (4,643)     (4,095)     (9,505) (9,030)
Internal Research and Development [Member] | Significant Segment Expense Category [Member]                
Segment Reporting [Line Items]                
Research and development expense $ (11,848)     $ (10,704)     $ (34,421) $ (26,597)