Basic and diluted net loss per share is computed by dividing net loss by the weighted-average common shares outstanding. The weighted-average common shares outstanding used in the basic and diluted net loss per share calculation includes pre-funded

warrants issued in connection with the Company’s underwritten offerings. As of September 30, 2026 and September 30, 2025, 445,422 and 385,899 pre-funded warrants were outstanding, respectively.

The following table sets forth the computation of the Company’s basic and diluted net loss per share (in thousands, except share and per share data):


	Three Months Ended September 30,						Nine Months Ended September 30,
	2026			2025			2026			2025
Numerator:
Net loss	$	(59,535	)	$	(62,321	)	$	(182,571	)	$	(151,653	)
Denominator:
Weighted-average common shares outstanding, basic and diluted		38,904,676			35,178,691			38,695,405			34,516,134
Net loss per share, basic and diluted	$	(1.53	)	$	(1.77	)	$	(4.72	)	$	(4.39	)

The Company has generated a net loss in all periods presented, so the basic and diluted net loss per share are the same, as the inclusion of the potentially dilutive securities would be anti-dilutive. As of September 30, 2026 and September 30, 2025, the Company excluded the following potential common shares from the computation of diluted net loss per share because including them would have had an anti-dilutive effect:


	As of September 30,
	2026		2025
Options to purchase common stock		3,487,422		3,433,481
Restricted stock units		1,351,975		1,096,595
Employee stock purchase program		12,639		13,944