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  <xs:element id="avtx_CollaborativeArrangementLicenseRightsRoyaltyPercentage" abstract="false" name="CollaborativeArrangementLicenseRightsRoyaltyPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="avtx_CollaborativeArrangementRightsAndObligationsCumulativeMilestonePaymentExpenseRecognizedToDate" abstract="false" name="CollaborativeArrangementRightsAndObligationsCumulativeMilestonePaymentExpenseRecognizedToDate" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_CollaborativeArrangementRightsAndObligationsUpfrontFee" abstract="false" name="CollaborativeArrangementRightsAndObligationsUpfrontFee" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_CollaborativeArrangementRightsAndObligationsLicenseFee" abstract="false" name="CollaborativeArrangementRightsAndObligationsLicenseFee" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_CollaborativeArrangementRoyaltyTerm" abstract="false" name="CollaborativeArrangementRoyaltyTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="avtx_ContractWithCustomerLicenseAgreementExpirationTerm" abstract="false" name="ContractWithCustomerLicenseAgreementExpirationTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="avtx_RevenueRemainingPerformanceObligationVariableConsiderationAmount" abstract="false" name="RevenueRemainingPerformanceObligationVariableConsiderationAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_ContractWithCustomerRevenueRecognizedToDateFromMilestonePayments" abstract="false" name="ContractWithCustomerRevenueRecognizedToDateFromMilestonePayments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_UpfrontPaymentPaid" abstract="false" name="UpfrontPaymentPaid" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_AssetAcquisitionConsiderationTransferredLiabilities" abstract="false" name="AssetAcquisitionConsiderationTransferredLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_ContingentMilestoneUpfrontPaymentPercentage" abstract="false" name="ContingentMilestoneUpfrontPaymentPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:pureItemType"/>
  <xs:element id="avtx_ContingentMilestonePayment" abstract="false" name="ContingentMilestonePayment" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_MaximumPotentialPayments" abstract="false" name="MaximumPotentialPayments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_RoyaltyAgreementPaymentReceived" abstract="false" name="RoyaltyAgreementPaymentReceived" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_RoyaltyAgreementPeriodAfterPublicLaunchToTerminateAgreement" abstract="false" name="RoyaltyAgreementPeriodAfterPublicLaunchToTerminateAgreement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="avtx_RoyaltyAgreementBuyoutOptionPercentageOfNetPresentValueOfRoyaltyPayments" abstract="false" name="RoyaltyAgreementBuyoutOptionPercentageOfNetPresentValueOfRoyaltyPayments" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="avtx_ReportableSegmentMember" abstract="true" name="ReportableSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="avtx_NonclinicalExpenses" abstract="false" name="NonclinicalExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_ClinicalExpenses" abstract="false" name="ClinicalExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_ChemistryManufacturingAndControlExpenses" abstract="false" name="ChemistryManufacturingAndControlExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_LicenseAndMilestoneExpenses" abstract="false" name="LicenseAndMilestoneExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="avtx_JenniferRileyMember" abstract="true" name="JenniferRileyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="avtx_GarryNeilM.D.TradingArrangementAdoptionMember" abstract="true" name="GarryNeilM.D.TradingArrangementAdoptionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="avtx_GarryNeilM.D.Member" abstract="true" name="GarryNeilM.D.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="avtx_ChristopherSullivanMember" abstract="true" name="ChristopherSullivanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="avtx_GarryNeilM.D.TradingArrangementTerminationMember" abstract="true" name="GarryNeilM.D.TradingArrangementTerminationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="avtx_ChristopherSullivanTradingArrangementRestrictedStockUnitsMember" abstract="true" name="ChristopherSullivanTradingArrangementRestrictedStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
