Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands |
Total |
At The Market Offering |
Common Stock Financings |
Common Stock |
Common Stock
At The Market Offering
|
Common Stock
Common Stock Financings
|
Additional Paid-in Capital |
Additional Paid-in Capital
At The Market Offering
|
Additional Paid-in Capital
Common Stock Financings
|
Accumulated Other Comprehensive Income (Loss) |
Accumulated Deficit |
| Beginning balance at Dec. 31, 2024 |
|
$ 250,504
|
|
|
|
$ 22
|
|
|
$ 1,855,318
|
|
|
$ 14
|
$ (1,604,850)
|
| Beginning balance (in shares) at Dec. 31, 2024 |
|
|
|
|
|
223,923
|
|
|
|
|
|
|
|
| Fees incurred related to issuance of common stock |
|
(171)
|
|
|
|
|
|
|
(171)
|
|
|
|
|
| Vesting of restricted stock (in shares) |
|
|
|
|
|
960
|
|
|
|
|
|
|
|
| Exercise of stock options |
|
1,127
|
|
|
|
$ 1
|
|
|
1,126
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
|
|
580
|
|
|
|
|
|
|
|
| Stock-based compensation expense |
|
7,022
|
|
|
|
|
|
|
7,022
|
|
|
|
|
| Unrealized loss on marketable securities, net |
|
(14)
|
|
|
|
|
|
|
|
|
|
(14)
|
|
| Net income (loss) |
|
(49,389)
|
|
|
|
|
|
|
|
|
|
|
(49,389)
|
| Ending balance at Mar. 31, 2025 |
|
209,079
|
|
|
|
$ 23
|
|
|
1,863,295
|
|
|
|
(1,654,239)
|
| Ending balance (in shares) at Mar. 31, 2025 |
|
|
|
|
|
225,463
|
|
|
|
|
|
|
|
| Beginning balance at Dec. 31, 2024 |
|
250,504
|
|
|
|
$ 22
|
|
|
1,855,318
|
|
|
14
|
(1,604,850)
|
| Beginning balance (in shares) at Dec. 31, 2024 |
|
|
|
|
|
223,923
|
|
|
|
|
|
|
|
| Net income (loss) |
[1] |
(185,341)
|
|
|
|
|
|
|
|
|
|
|
|
| Ending balance at Sep. 30, 2025 |
|
195,308
|
|
|
|
$ 26
|
|
|
1,985,452
|
|
|
21
|
(1,790,191)
|
| Ending balance (in shares) at Sep. 30, 2025 |
|
|
|
|
|
262,264
|
|
|
|
|
|
|
|
| Beginning balance at Mar. 31, 2025 |
|
209,079
|
|
|
|
$ 23
|
|
|
1,863,295
|
|
|
|
(1,654,239)
|
| Beginning balance (in shares) at Mar. 31, 2025 |
|
|
|
|
|
225,463
|
|
|
|
|
|
|
|
| Fees incurred related to issuance of common stock |
|
|
|
$ (174)
|
|
|
|
|
|
|
|
|
|
| Issuance of common stock, net of issuance costs |
|
|
|
315
|
|
|
|
|
|
$ 315
|
|
|
|
| Issuance of common stock, net of issuance costs (in shares) |
|
|
|
|
|
|
170
|
|
|
|
|
|
|
| Exercise of pre-funded warrants (in shares) |
|
|
|
|
|
4,445
|
|
|
|
|
|
|
|
| Vesting of restricted stock (in shares) |
|
|
|
|
|
203
|
|
|
|
|
|
|
|
| Exercise of stock options |
|
148
|
|
|
|
|
|
|
148
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
|
|
102
|
|
|
|
|
|
|
|
| Issuance of common stock related to employee stock purchase plan |
|
185
|
|
|
|
|
|
|
185
|
|
|
|
|
| Issuance of common stock related to employee stock purchase plan (in shares) |
|
|
|
|
|
127
|
|
|
|
|
|
|
|
| Stock-based compensation expense |
|
6,629
|
|
|
|
|
|
|
6,629
|
|
|
|
|
| Net income (loss) |
|
(93,800)
|
|
|
|
|
|
|
|
|
|
|
(93,800)
|
| Ending balance at Jun. 30, 2025 |
|
122,556
|
|
|
|
$ 23
|
|
|
1,870,572
|
|
|
|
(1,748,039)
|
| Ending balance (in shares) at Jun. 30, 2025 |
|
|
|
|
|
230,510
|
|
|
|
|
|
|
|
| Fees incurred related to issuance of common stock |
|
|
|
(886)
|
$ (5,625)
|
|
|
|
|
|
|
|
|
| Issuance of common stock, net of issuance costs |
|
|
|
$ 28,625
|
$ 80,625
|
|
$ 1
|
$ 2
|
|
$ 28,624
|
$ 80,623
|
|
|
| Issuance of common stock, net of issuance costs (in shares) |
|
|
|
|
|
|
7,272
|
24,254
|
|
|
|
|
|
| Vesting of restricted stock (in shares) |
|
|
|
|
|
153
|
|
|
|
|
|
|
|
| Exercise of stock options |
|
158
|
|
|
|
|
|
|
158
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
|
|
75
|
|
|
|
|
|
|
|
| Stock-based compensation expense |
|
5,475
|
|
|
|
|
|
|
5,475
|
|
|
|
|
| Unrealized loss on marketable securities, net |
|
21
|
|
|
|
|
|
|
|
|
|
21
|
|
| Net income (loss) |
|
(42,152)
|
[1] |
|
|
|
|
|
|
|
|
|
(42,152)
|
| Ending balance at Sep. 30, 2025 |
|
195,308
|
|
|
|
$ 26
|
|
|
1,985,452
|
|
|
21
|
(1,790,191)
|
| Ending balance (in shares) at Sep. 30, 2025 |
|
|
|
|
|
262,264
|
|
|
|
|
|
|
|
| Beginning balance at Dec. 31, 2025 |
|
$ 160,884
|
|
|
|
$ 27
|
|
|
2,009,845
|
|
|
28
|
(1,849,016)
|
| Beginning balance (in shares) at Dec. 31, 2025 |
|
266,732
|
|
|
|
266,732
|
|
|
|
|
|
|
|
| Fees incurred related to issuance of common stock |
|
$ (125)
|
|
|
|
|
|
|
(125)
|
|
|
|
|
| Exercise of pre-funded warrants (in shares) |
|
|
|
|
|
2,192
|
|
|
|
|
|
|
|
| Vesting of restricted stock (in shares) |
|
|
|
|
|
864
|
|
|
|
|
|
|
|
| Exercise of stock options |
|
59
|
|
|
|
|
|
|
59
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
|
|
29
|
|
|
|
|
|
|
|
| Stock-based compensation expense |
|
5,662
|
|
|
|
|
|
|
5,662
|
|
|
|
|
| Unrealized loss on marketable securities, net |
|
(30)
|
|
|
|
|
|
|
|
|
|
(30)
|
|
| Net income (loss) |
|
(47,210)
|
|
|
|
|
|
|
|
|
|
|
(47,210)
|
| Ending balance at Mar. 31, 2026 |
|
119,240
|
|
|
|
$ 27
|
|
|
2,015,441
|
|
|
(2)
|
(1,896,226)
|
| Ending balance (in shares) at Mar. 31, 2026 |
|
|
|
|
|
269,817
|
|
|
|
|
|
|
|
| Beginning balance at Dec. 31, 2025 |
|
$ 160,884
|
|
|
|
$ 27
|
|
|
2,009,845
|
|
|
28
|
(1,849,016)
|
| Beginning balance (in shares) at Dec. 31, 2025 |
|
266,732
|
|
|
|
266,732
|
|
|
|
|
|
|
|
| Exercise of stock options (in shares) |
|
117
|
|
|
|
|
|
|
|
|
|
|
|
| Net income (loss) |
|
$ (90,444)
|
|
|
|
|
|
|
|
|
|
|
|
| Ending balance at Sep. 30, 2026 |
|
$ 180,364
|
|
|
|
$ 30
|
|
|
2,119,898
|
|
|
(104)
|
(1,939,460)
|
| Ending balance (in shares) at Sep. 30, 2026 |
|
299,521
|
|
|
|
299,521
|
|
|
|
|
|
|
|
| Beginning balance at Mar. 31, 2026 |
|
$ 119,240
|
|
|
|
$ 27
|
|
|
2,015,441
|
|
|
(2)
|
(1,896,226)
|
| Beginning balance (in shares) at Mar. 31, 2026 |
|
|
|
|
|
269,817
|
|
|
|
|
|
|
|
| Fees incurred related to issuance of common stock |
|
(1,252)
|
|
|
|
|
|
|
|
|
|
|
|
| Issuance of common stock, net of issuance costs |
|
89,752
|
|
|
|
$ 3
|
|
|
89,749
|
|
|
|
|
| Issuance of common stock, net of issuance costs (in shares) |
|
|
|
|
|
29,115
|
|
|
|
|
|
|
|
| Issuance of common stock allocated to stock purchase option |
|
3,688
|
|
|
|
|
|
|
3,688
|
|
|
|
|
| Vesting of restricted stock (in shares) |
|
|
|
|
|
230
|
|
|
|
|
|
|
|
| Exercise of stock options |
|
59
|
|
|
|
|
|
|
59
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
|
|
29
|
|
|
|
|
|
|
|
| Issuance of common stock related to employee stock purchase plan |
|
186
|
|
|
|
|
|
|
186
|
|
|
|
|
| Issuance of common stock related to employee stock purchase plan (in shares) |
|
|
|
|
|
115
|
|
|
|
|
|
|
|
| Stock-based compensation expense |
|
5,342
|
|
|
|
|
|
|
5,342
|
|
|
|
|
| Unrealized loss on marketable securities, net |
|
(64)
|
|
|
|
|
|
|
|
|
|
(64)
|
|
| Net income (loss) |
|
(63,635)
|
|
|
|
|
|
|
|
|
|
|
(63,635)
|
| Ending balance at Jun. 30, 2026 |
|
154,568
|
|
|
|
$ 30
|
|
|
2,114,465
|
|
|
(66)
|
(1,959,861)
|
| Ending balance (in shares) at Jun. 30, 2026 |
|
|
|
|
|
299,306
|
|
|
|
|
|
|
|
| Fees incurred related to issuance of common stock |
|
(9)
|
|
|
|
|
|
|
(9)
|
|
|
|
|
| Vesting of restricted stock (in shares) |
|
|
|
|
|
156
|
|
|
|
|
|
|
|
| Exercise of stock options |
|
117
|
|
|
|
|
|
|
117
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
|
|
59
|
|
|
|
|
|
|
|
| Stock-based compensation expense |
|
5,325
|
|
|
|
|
|
|
5,325
|
|
|
|
|
| Unrealized loss on marketable securities, net |
|
(38)
|
|
|
|
|
|
|
|
|
|
(38)
|
|
| Net income (loss) |
|
20,401
|
|
|
|
|
|
|
|
|
|
|
20,401
|
| Ending balance at Sep. 30, 2026 |
|
$ 180,364
|
|
|
|
$ 30
|
|
|
$ 2,119,898
|
|
|
$ (104)
|
$ (1,939,460)
|
| Ending balance (in shares) at Sep. 30, 2026 |
|
299,521
|
|
|
|
299,521
|
|
|
|
|
|
|
|
|
|