v3.26.3
Organization - Additional Information (Details) - USD ($)
$ / shares in Units, shares in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended
Aug. 31, 2026
Apr. 30, 2026
Mar. 31, 2026
Aug. 31, 2025
Feb. 29, 2024
Jun. 30, 2026
Sep. 30, 2025
Jun. 30, 2025
Sep. 30, 2026
Sep. 30, 2025
Dec. 31, 2025
Description Of Organization [Line Items]                      
Common stock, shares issued                 299,521   266,732
Net proceeds from issuance of common stock                 $ 89,622,000 $ 109,724,000  
Accumulated deficit                 1,939,460,000   $ 1,849,016,000
Cash, cash equivalents and marketable securities                 121,700,000    
Success payment liabilities                 14,200,000    
Contingent consideration                 $ 44,100,000    
Aggregate common stock value sold           $ 89,752,000          
ATM facility                      
Description Of Organization [Line Items]                      
Aggregate common stock value sold             $ 28,625,000 $ 315,000      
Over Allotment Option                      
Description Of Organization [Line Items]                      
Net proceeds from issuance of common stock       $ 80,600,000 $ 180,000,000            
Number of warrants to purchase common stock       1,500 12,700            
Common Stock                      
Description Of Organization [Line Items]                      
Aggregate common stock sold           29,115          
Aggregate common stock value sold           $ 3,000          
Common Stock | ATM facility                      
Description Of Organization [Line Items]                      
Aggregate common stock sold             7,272 170      
Aggregate common stock value sold             $ 1,000        
Common Stock | Underwritten Public Offering                      
Description Of Organization [Line Items]                      
Aggregate common stock sold       24,300 21,800            
Common Stock | Underwriters' Option To Purchase Additional Shares                      
Description Of Organization [Line Items]                      
Aggregate common stock sold       3,400 4,500            
Mayo Clinic Initial Shares | Stock Purchase Agreement                      
Description Of Organization [Line Items]                      
Common stock, shares issued 7,500 7,500                  
Stock price price per share   $ 3.33                  
Net proceeds from issuance of common stock   $ 25,000,000                  
Mayo Clinic Election | Stock Purchase Agreement                      
Description Of Organization [Line Items]                      
Stock price price per share $ 3.33                    
Net proceeds from issuance of common stock $ 25,000,000                    
Cowen | ATM facility | Sales Agreement | Maximum                      
Description Of Organization [Line Items]                      
Aggregate common stock value sold     $ 150,000,000