v3.26.3
License and Collaborations (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended 12 Months Ended
Mar. 31, 2027
Sep. 30, 2026
Jun. 30, 2026
Dec. 31, 2025
Sep. 30, 2025
Mar. 31, 2025
Sep. 30, 2026
Sep. 30, 2025
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2020
Dec. 31, 2017
License And Collaboration Agreements [Line Items]                        
Receivable from collaboration partners   $ 18   $ 11     $ 18          
Other current liabilities   141   154     141          
Other noncurrent liabilities   125   135     125          
Taiho Collaboration Agreement                        
License And Collaboration Agreements [Line Items]                        
Milestone payments     $ 30                  
Receivable from collaboration partners   18   10     18          
Other liabilities   32   44     32          
AstraZeneca Agreement                        
License And Collaboration Agreements [Line Items]                        
Milestone payments                     $ 18  
Development cost recorded within research and development expenses   12     $ 7   21 $ 16        
Other current liabilities   33         33          
Other noncurrent liabilities       12                
Taiho Pharmaceutical Co., Ltd | Taiho Agreement                        
License And Collaboration Agreements [Line Items]                        
Option period                       5 years
Non refundable and non creditable cash payments                       $ 35
Payment for option exercise       15                
Royalties payable term                       10 years
Reimbursement of research and development expense   5     7   16 24        
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum                        
License And Collaboration Agreements [Line Items]                        
Payment for option exercise                       $ 3
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum                        
License And Collaboration Agreements [Line Items]                        
Payment for option exercise                       15
Additional clinical and regulatory milestone payments receivable   15   172               130
Contingent milestone payments receivable       $ 145               $ 145
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum | Forecast                        
License And Collaboration Agreements [Line Items]                        
Remaining milestone payments $ 15                      
STAR-221 Development Activities | Taiho Collaboration Agreement                        
License And Collaboration Agreements [Line Items]                        
Milestone payments                   $ 28    
STAR-121 Development Activities | Taiho Collaboration Agreement                        
License And Collaboration Agreements [Line Items]                        
Milestone payments                 $ 26      
PRISM-1 Development Activities | Taiho Collaboration Agreement                        
License And Collaboration Agreements [Line Items]                        
Milestone payments           $ 19            
WuXi Biologics License Agreement | anti-PD-1                        
License And Collaboration Agreements [Line Items]                        
Development milestone expense   0     0   0 0        
WuXi Biologics License Agreement | anti-CD39                        
License And Collaboration Agreements [Line Items]                        
Development milestone expense   0     0   0 0        
WuXi Biologics License Agreement | Maximum | anti-PD-1                        
License And Collaboration Agreements [Line Items]                        
Clinical regulatory milestone payments             50          
Clinical, regulatory and commercialization milestone payments             375          
WuXi Biologics License Agreement | Maximum | anti-CD39                        
License And Collaboration Agreements [Line Items]                        
Additional clinical, regulatory and commercialization milestone payments             14          
Abmuno License Agreement                        
License And Collaboration Agreements [Line Items]                        
Development milestone expense   $ 0     $ 0   0 $ 0        
Additional clinical, regulatory and commercialization milestone payments             $ 88