S-3 424B5 EX-FILING FEES 333-293736 0001787306 Arcutis Biotherapeutics, Inc. N/A The prospectus is not a final prospectus for the related offering. Y N 0001787306 2026-11-03 2026-11-03 0001787306 1 2026-11-03 2026-11-03 0001787306 1 2026-11-03 2026-11-03 0001787306 2 2026-11-03 2026-11-03 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-3

Arcutis Biotherapeutics, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Common Stock, $0.0001 par value per share 457(o) $ 200,000,000.00 0.000087 $ 17,400.00
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 200,000,000.00

$ 17,400.00

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 2,694.07

Net Fee Due:

$ 14,705.93

Offering Note

1

The registration fee is calculated in accordance with Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"), based on the proposed maximum aggregate offering price of $200,000,000. In accordance with Rules 456(b) and 457(r) under the Securities Act, the registrant initially deferred payment of all of the registration fees for the Registration Statement on Form S-3 (Registration No. 333-293736), filed on February 25, 2026. On January 31, 2024, the registrant filed a Registration Statement on Form S-3 (File No. 333-276794) (the "Prior Registration Statement") relating to the offer and sale of shares of its common stock, $0.0001 par value per share (the "Common Stock") with a proposed maximum aggregate offering price of up to $100,000,000 under its then current "at-the-market" program (the "2024 ATM Program"). Of such $100,000,000, (i) $81,747,499 consisted of unsold securities previously registered on the registrant's Registration Statement on Form S-3 (File No. 333-252612), filed on February 1, 2021, that were included in the Prior Registration Statement pursuant to Rule 415(a)(6) under the Securities Act, and (ii) $18,252,501 consisted of newly registered securities, with respect to which the registrant paid a filing fee of $2,694.07. No shares of Common Stock were sold under the 2024 ATM Program and the 2024 ATM Program terminated on November 4, 2026. Pursuant to Rule 457(p) under the Securities Act, the registration fee of $2,694.07 previously paid with respect to the $18,252,501 of unsold newly registered securities of the 2024 ATM Program may be used to offset the registration fee due in connection with this offering.

Table 2: Fee Offset Claims and Sources ☐Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims
Fee Offset Sources
Rule 457(p)
Fee Offset Claims 1 Arcutis Biotherapeutics, Inc. S-3 333-276794 01/31/2024 $ 2,694.07 Equity Common Stock, $0.0001 par value per share $ 18,252,501.00
Fee Offset Sources 2 Arcutis Biotherapeutics, Inc. S-3 333-276794 01/31/2024 $ 2,694.07

Rule 457(p) Statement of Withdrawal, Termination, or Completion:

1

See footnote above.

Offset Note

2

See footnote above.

Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date