<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:01a0eef3-15b1-7844-9a84-7e2304bf97b4,g:557263f4-7a5e-49d6-8f8b-581a244d4ce8-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://aquestive.com/role/Cover" xlink:type="simple" xlink:href="aqst-20260930.xsd#Cover"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_01a0eef3-16e0-749d-ac77-22eab59621e6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_DocumentType_01a0eef3-16e0-749d-ac77-22eab59621e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_01a0eef3-16e0-7c1a-b8f0-8924d2b2f4b2" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentQuarterlyReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_DocumentQuarterlyReport_01a0eef3-16e0-7c1a-b8f0-8924d2b2f4b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_01a0eef3-16e0-7bc2-b107-7bc6a19e204c" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_DocumentPeriodEndDate_01a0eef3-16e0-7bc2-b107-7bc6a19e204c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_01a0eef3-16e0-7a04-85e1-e65a2e388a59" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_DocumentTransitionReport_01a0eef3-16e0-7a04-85e1-e65a2e388a59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_01a0eef3-16e0-7837-b88b-ec8007b6d9fa" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityFileNumber_01a0eef3-16e0-7837-b88b-ec8007b6d9fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_01a0eef3-16e0-7903-8832-83e3e251f89f" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityRegistrantName_01a0eef3-16e0-7903-8832-83e3e251f89f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_01a0eef3-16e0-72db-a9a0-ad1b733398e7" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityIncorporationStateCountryCode_01a0eef3-16e0-72db-a9a0-ad1b733398e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_01a0eef3-16e0-72d2-b1f7-deaa4e36d3a6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityAddressAddressLine1_01a0eef3-16e0-72d2-b1f7-deaa4e36d3a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_01a0eef3-16e0-7316-b7a9-b5281c39d485" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityAddressCityOrTown_01a0eef3-16e0-7316-b7a9-b5281c39d485" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_01a0eef3-16e0-7b5b-af06-dce972cb3f3e" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityAddressStateOrProvince_01a0eef3-16e0-7b5b-af06-dce972cb3f3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_01a0eef3-16e0-7cd9-a7c0-578fa8635661" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityAddressPostalZipCode_01a0eef3-16e0-7cd9-a7c0-578fa8635661" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_01a0eef3-16e0-7d8f-8413-076ddad85074" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityTaxIdentificationNumber_01a0eef3-16e0-7d8f-8413-076ddad85074" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_01a0eef3-16e0-798b-abee-018c28b0a57f" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_CityAreaCode_01a0eef3-16e0-798b-abee-018c28b0a57f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_01a0eef3-16e0-7716-907a-17368dd82a49" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_LocalPhoneNumber_01a0eef3-16e0-7716-907a-17368dd82a49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_01a0eef3-16e0-7dfe-88e0-5fd7d34c3cc1" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_Security12bTitle_01a0eef3-16e0-7dfe-88e0-5fd7d34c3cc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_01a0eef3-16e0-7ad7-bb30-d7c3ea685d43" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_TradingSymbol_01a0eef3-16e0-7ad7-bb30-d7c3ea685d43" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_01a0eef3-16e0-7900-8d07-61835d10572d" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_SecurityExchangeName_01a0eef3-16e0-7900-8d07-61835d10572d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_01a0eef3-16e0-76f7-a410-0b872b5a9a90" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityCurrentReportingStatus_01a0eef3-16e0-76f7-a410-0b872b5a9a90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_01a0eef3-16e0-76f1-8e8f-8f588cbc22d6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityInteractiveDataCurrent_01a0eef3-16e0-76f1-8e8f-8f588cbc22d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_01a0eef3-16e0-75ff-a37e-f4af9bd1c50c" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityFilerCategory_01a0eef3-16e0-75ff-a37e-f4af9bd1c50c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_01a0eef3-16e0-72c3-8ee1-08a680144621" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntitySmallBusiness_01a0eef3-16e0-72c3-8ee1-08a680144621" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_01a0eef3-16e0-70d9-8bb8-255d56cb6972" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityEmergingGrowthCompany_01a0eef3-16e0-70d9-8bb8-255d56cb6972" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_01a0eef3-16e0-7855-8be5-4c012c3942c6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityShellCompany_01a0eef3-16e0-7855-8be5-4c012c3942c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_01a0eef3-16e0-7040-a9de-f497c51da045" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_01a0eef3-16e0-7040-a9de-f497c51da045" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_01a0eef3-16e0-7c93-820c-fc074cb6bc73" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_EntityCentralIndexKey_01a0eef3-16e0-7c93-820c-fc074cb6bc73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_01a0eef3-16e0-7ac1-9123-fb7f1b337192" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_CurrentFiscalYearEndDate_01a0eef3-16e0-7ac1-9123-fb7f1b337192" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_01a0eef3-16e0-770c-88be-7d2b11ca65c5" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_DocumentFiscalYearFocus_01a0eef3-16e0-770c-88be-7d2b11ca65c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_01a0eef3-16e0-7614-9682-4a8861898722" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_DocumentFiscalPeriodFocus_01a0eef3-16e0-7614-9682-4a8861898722" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_01a0eef3-16e0-70de-adeb-e1b8056b4627" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0eef3-16e0-74c3-bdbd-4462315f7815" xlink:to="loc_dei_AmendmentFlag_01a0eef3-16e0-70de-adeb-e1b8056b4627" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CondensedBalanceSheets" xlink:type="simple" xlink:href="aqst-20260930.xsd#CondensedBalanceSheets"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CondensedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_01a0eef3-16e0-71f5-b5e6-42420ce4311f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_01a0eef3-16e0-72d2-8407-6065334cfc31" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_01a0eef3-16e0-71f5-b5e6-42420ce4311f" xlink:to="loc_us-gaap_AssetsAbstract_01a0eef3-16e0-72d2-8407-6065334cfc31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_01a0eef3-16e0-76bc-b535-4911c44089fe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_01a0eef3-16e0-72d2-8407-6065334cfc31" xlink:to="loc_us-gaap_AssetsCurrentAbstract_01a0eef3-16e0-76bc-b535-4911c44089fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_01a0eef3-16e0-75b8-ab29-01ac72b3ae16" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_01a0eef3-16e0-76bc-b535-4911c44089fe" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_01a0eef3-16e0-75b8-ab29-01ac72b3ae16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesNetCurrent_01a0eef3-16e0-7bf5-b479-12e7471db771" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReceivablesNetCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_01a0eef3-16e0-76bc-b535-4911c44089fe" xlink:to="loc_us-gaap_ReceivablesNetCurrent_01a0eef3-16e0-7bf5-b479-12e7471db771" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_01a0eef3-16e0-7d5d-b9bb-c0d5dd597afe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_01a0eef3-16e0-76bc-b535-4911c44089fe" xlink:to="loc_us-gaap_InventoryNet_01a0eef3-16e0-7d5d-b9bb-c0d5dd597afe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_01a0eef3-16e0-71dc-83d8-392c6d7f7cd0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_01a0eef3-16e0-76bc-b535-4911c44089fe" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_01a0eef3-16e0-71dc-83d8-392c6d7f7cd0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_01a0eef3-16e0-7fdf-b3c3-d33de89c48e7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_01a0eef3-16e0-76bc-b535-4911c44089fe" xlink:to="loc_us-gaap_AssetsCurrent_01a0eef3-16e0-7fdf-b3c3-d33de89c48e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_01a0eef3-16e0-75f2-964f-6cbf3929d018" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_01a0eef3-16e0-72d2-8407-6065334cfc31" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_01a0eef3-16e0-75f2-964f-6cbf3929d018" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_01a0eef3-16e0-776f-a3cc-acba0188c73a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_01a0eef3-16e0-72d2-8407-6065334cfc31" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_01a0eef3-16e0-776f-a3cc-acba0188c73a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_01a0eef3-16e0-70a9-990a-78017f4cd56c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_01a0eef3-16e0-72d2-8407-6065334cfc31" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_01a0eef3-16e0-70a9-990a-78017f4cd56c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_01a0eef3-16e0-747e-8f66-3c201794a42c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Assets"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_01a0eef3-16e0-72d2-8407-6065334cfc31" xlink:to="loc_us-gaap_Assets_01a0eef3-16e0-747e-8f66-3c201794a42c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_01a0eef3-16e0-71f5-b5e6-42420ce4311f" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_01a0eef3-16e0-758c-aefe-15bd5ba74252" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_us-gaap_AccountsPayableCurrent_01a0eef3-16e0-758c-aefe-15bd5ba74252" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_01a0eef3-16e0-7237-b761-e97761d824fe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_01a0eef3-16e0-7237-b761-e97761d824fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_01a0eef3-16e0-7d10-81d8-4b9104f2326e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_01a0eef3-16e0-7d10-81d8-4b9104f2326e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_01a0eef3-16e0-74aa-bae2-815673679386" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_01a0eef3-16e0-74aa-bae2-815673679386" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedCurrent_01a0eef3-16e0-7924-9fca-b1768c2e42d1" xlink:href="aqst-20260930.xsd#aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedCurrent_01a0eef3-16e0-7924-9fca-b1768c2e42d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationsLiabilityCurrent_01a0eef3-16e0-797a-90ec-57af04cf3560" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationsLiabilityCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_aqst_RoyaltyObligationsLiabilityCurrent_01a0eef3-16e0-797a-90ec-57af04cf3560" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtCurrent_01a0eef3-16e0-7009-9447-9fb11798f3cc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_us-gaap_DebtCurrent_01a0eef3-16e0-7009-9447-9fb11798f3cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_01a0eef3-16e0-7c0b-a073-1260abf3f338" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_01a0eef3-16e0-72a9-9f23-068b0918ac18" xlink:to="loc_us-gaap_LiabilitiesCurrent_01a0eef3-16e0-7c0b-a073-1260abf3f338" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_01a0eef3-16e0-7164-9809-71006d363df3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligations"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_01a0eef3-16e0-7164-9809-71006d363df3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationLiabilityNoncurrent_01a0eef3-16e0-7caf-a349-ca6982c7caf5" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationLiabilityNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_aqst_RoyaltyObligationLiabilityNoncurrent_01a0eef3-16e0-7caf-a349-ca6982c7caf5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedNoncurrent_01a0eef3-16e0-7fba-bbc9-4a71cee30611" xlink:href="aqst-20260930.xsd#aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedNoncurrent_01a0eef3-16e0-7fba-bbc9-4a71cee30611" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_01a0eef3-16e0-735f-a8a1-338ea2f2914e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_01a0eef3-16e0-735f-a8a1-338ea2f2914e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_01a0eef3-16e0-7676-afd2-c05a486bfd50" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_01a0eef3-16e0-7676-afd2-c05a486bfd50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_01a0eef3-16e0-73ef-9027-a5d038fab245" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_01a0eef3-16e0-73ef-9027-a5d038fab245" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_01a0eef3-16e0-7048-b5df-35c0b4fc0743" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Liabilities"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_Liabilities_01a0eef3-16e0-7048-b5df-35c0b4fc0743" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_01a0eef3-16e0-7671-8c60-9affce3d8f00" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_CommitmentsAndContingencies_01a0eef3-16e0-7671-8c60-9affce3d8f00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-797a-9471-381053728653" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-797a-9471-381053728653" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_01a0eef3-16e0-7afa-9b2c-1f666f976620" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-797a-9471-381053728653" xlink:to="loc_us-gaap_CommonStockValue_01a0eef3-16e0-7afa-9b2c-1f666f976620" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_01a0eef3-16e0-795f-8722-6ce0ff87ae6b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-797a-9471-381053728653" xlink:to="loc_us-gaap_AdditionalPaidInCapital_01a0eef3-16e0-795f-8722-6ce0ff87ae6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_01a0eef3-16e0-7683-aa98-6fdc01ed292b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-797a-9471-381053728653" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_01a0eef3-16e0-7683-aa98-6fdc01ed292b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_01a0eef3-16e0-7f55-b5e1-545d3c24e65a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-797a-9471-381053728653" xlink:to="loc_us-gaap_StockholdersEquity_01a0eef3-16e0-7f55-b5e1-545d3c24e65a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a0eef3-16e0-7f05-93ef-936c82844e2c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_01a0eef3-16e0-7213-bf61-0f7715460d7c" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_01a0eef3-16e0-7f05-93ef-936c82844e2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CondensedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="aqst-20260930.xsd#CondensedBalanceSheetsParenthetical"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CondensedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_01a0eef3-16e0-7bf6-9da3-b5cbdd648057" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-7dfb-a444-34216837882c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_01a0eef3-16e0-7bf6-9da3-b5cbdd648057" xlink:to="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-7dfb-a444-34216837882c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_01a0eef3-16e0-7235-9601-57f6e356d9dc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-7dfb-a444-34216837882c" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_01a0eef3-16e0-7235-9601-57f6e356d9dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_01a0eef3-16e0-7ac5-87de-58115cad8611" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-7dfb-a444-34216837882c" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_01a0eef3-16e0-7ac5-87de-58115cad8611" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_01a0eef3-16e0-721d-a520-06ba26c8cff4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-7dfb-a444-34216837882c" xlink:to="loc_us-gaap_CommonStockSharesIssued_01a0eef3-16e0-721d-a520-06ba26c8cff4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_01a0eef3-16e0-70ae-a20b-8c75951b3a33" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_01a0eef3-16e0-7dfb-a444-34216837882c" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_01a0eef3-16e0-70ae-a20b-8c75951b3a33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CondensedStatementsofOperationsandComprehensiveLoss" xlink:type="simple" xlink:href="aqst-20260930.xsd#CondensedStatementsofOperationsandComprehensiveLoss"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CondensedStatementsofOperationsandComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-73ed-9877-2df541731009" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-73ed-9877-2df541731009" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_01a0eef3-16e0-716b-a5da-5017a2d82dce" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_OperatingExpensesAbstract_01a0eef3-16e0-716b-a5da-5017a2d82dce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_01a0eef3-16e0-766c-9cf1-25b501cfa25d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_01a0eef3-16e0-716b-a5da-5017a2d82dce" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_01a0eef3-16e0-766c-9cf1-25b501cfa25d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfCostGoodOrServiceExtensibleList_01a0eef3-16e0-72f3-b879-a91fcb52e6a0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TypeOfCostGoodOrServiceExtensibleList"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostOfGoodsAndServicesSold_01a0eef3-16e0-766c-9cf1-25b501cfa25d" xlink:to="loc_us-gaap_TypeOfCostGoodOrServiceExtensibleList_01a0eef3-16e0-72f3-b879-a91fcb52e6a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_01a0eef3-16e0-712b-9a8c-54c4508a1871" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_01a0eef3-16e0-716b-a5da-5017a2d82dce" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_01a0eef3-16e0-712b-9a8c-54c4508a1871" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_01a0eef3-16e0-7c83-a689-dac1ec69bfb5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_01a0eef3-16e0-716b-a5da-5017a2d82dce" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_01a0eef3-16e0-7c83-a689-dac1ec69bfb5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_01a0eef3-16e0-7158-ac8b-1bfe217ca3ce" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostsAndExpenses"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_01a0eef3-16e0-716b-a5da-5017a2d82dce" xlink:to="loc_us-gaap_CostsAndExpenses_01a0eef3-16e0-7158-ac8b-1bfe217ca3ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_01a0eef3-16e0-7dea-b032-002f5e6e7e27" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_OperatingIncomeLoss_01a0eef3-16e0-7dea-b032-002f5e6e7e27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NonoperatingIncomeExpenseAbstract"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_01a0eef3-16e0-713b-8d61-049cdf80bc64" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_01a0eef3-16e0-713b-8d61-049cdf80bc64" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_01a0eef3-16e0-7738-b0ad-cb179287157d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:to="loc_us-gaap_InterestExpenseNonoperating_01a0eef3-16e0-7738-b0ad-cb179287157d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RoyaltyExpense_01a0eef3-16e0-7ace-a679-6dca946568f2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RoyaltyExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:to="loc_us-gaap_RoyaltyExpense_01a0eef3-16e0-7ace-a679-6dca946568f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_InterestExpenseSaleOfFutureRevenues_01a0eef3-16e0-7f38-97a6-ba00550a2df0" xlink:href="aqst-20260930.xsd#aqst_InterestExpenseSaleOfFutureRevenues"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:to="loc_aqst_InterestExpenseSaleOfFutureRevenues_01a0eef3-16e0-7f38-97a6-ba00550a2df0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_InterestAndOtherIncomeNet_01a0eef3-16e0-7f68-a3da-7876520525a8" xlink:href="aqst-20260930.xsd#aqst_InterestAndOtherIncomeNet"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:to="loc_aqst_InterestAndOtherIncomeNet_01a0eef3-16e0-7f68-a3da-7876520525a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a0eef3-16e0-7fe2-aa0e-bf6ec24b3183" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_01a0eef3-16e0-74ff-ae08-dd5b79f045df" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a0eef3-16e0-7fe2-aa0e-bf6ec24b3183" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-7198-84b5-a52c358dc7d8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-7198-84b5-a52c358dc7d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_01a0eef3-16e0-7291-a51e-8e13800839fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_01a0eef3-16e0-7291-a51e-8e13800839fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-16e0-7bb5-88cf-df7d0b8fc303" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-16e0-7bb5-88cf-df7d0b8fc303" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_01a0eef3-16e0-76fd-85c8-5821674298cc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-16e0-7bb5-88cf-df7d0b8fc303" xlink:to="loc_us-gaap_EarningsPerShareBasic_01a0eef3-16e0-76fd-85c8-5821674298cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_01a0eef3-16e0-7805-bcc4-f4c50516601d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-16e0-7bb5-88cf-df7d0b8fc303" xlink:to="loc_us-gaap_EarningsPerShareDiluted_01a0eef3-16e0-7805-bcc4-f4c50516601d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasicOtherDisclosuresAbstract_01a0eef3-16e0-7569-8dcc-cb463f7b5dfe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareBasicOtherDisclosuresAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_01a0eef3-16e0-7452-889e-8edba602d4f8" xlink:to="loc_us-gaap_EarningsPerShareBasicOtherDisclosuresAbstract_01a0eef3-16e0-7569-8dcc-cb463f7b5dfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_01a0eef3-16e0-708b-a4e6-3f5d8a0fd057" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicOtherDisclosuresAbstract_01a0eef3-16e0-7569-8dcc-cb463f7b5dfe" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_01a0eef3-16e0-708b-a4e6-3f5d8a0fd057" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_01a0eef3-16e0-7a68-9c87-ea2b634a6d44" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicOtherDisclosuresAbstract_01a0eef3-16e0-7569-8dcc-cb463f7b5dfe" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_01a0eef3-16e0-7a68-9c87-ea2b634a6d44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CondensedStatementsofChangesinStockholdersDeficit" xlink:type="simple" xlink:href="aqst-20260930.xsd#CondensedStatementsofChangesinStockholdersDeficit"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CondensedStatementsofChangesinStockholdersDeficit" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_01a0eef3-16e0-73ab-9b5b-9e4df23129e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_01a0eef3-16e0-7255-871c-826eae7e29dd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_01a0eef3-16e0-73ab-9b5b-9e4df23129e2" xlink:to="loc_us-gaap_StatementTable_01a0eef3-16e0-7255-871c-826eae7e29dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_01a0eef3-16e0-7c4a-a131-2bbe936bd8de" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_01a0eef3-16e0-7255-871c-826eae7e29dd" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_01a0eef3-16e0-7c4a-a131-2bbe936bd8de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_01a0eef3-16e0-7cf6-9b53-9a33f09b70e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_01a0eef3-16e0-7c4a-a131-2bbe936bd8de" xlink:to="loc_us-gaap_EquityComponentDomain_01a0eef3-16e0-7cf6-9b53-9a33f09b70e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_01a0eef3-16e0-7044-8542-bc7ca4a81ba8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_01a0eef3-16e0-7cf6-9b53-9a33f09b70e2" xlink:to="loc_us-gaap_CommonStockMember_01a0eef3-16e0-7044-8542-bc7ca4a81ba8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_01a0eef3-16e0-74d8-9f44-30abab51483e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_01a0eef3-16e0-7cf6-9b53-9a33f09b70e2" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_01a0eef3-16e0-74d8-9f44-30abab51483e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_01a0eef3-16e0-721d-92be-2ab4b60bbd6c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_01a0eef3-16e0-7cf6-9b53-9a33f09b70e2" xlink:to="loc_us-gaap_RetainedEarningsMember_01a0eef3-16e0-721d-92be-2ab4b60bbd6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-7f6d-aee6-9d0021b9ac00" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_01a0eef3-16e0-7255-871c-826eae7e29dd" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-7f6d-aee6-9d0021b9ac00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-7407-8bdf-ba0531a0ee9c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-7f6d-aee6-9d0021b9ac00" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-7407-8bdf-ba0531a0ee9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AtTheMarketOfferingMember_01a0eef3-16e0-7639-adcc-c1ea1d12d911" xlink:href="aqst-20260930.xsd#aqst_AtTheMarketOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-7407-8bdf-ba0531a0ee9c" xlink:to="loc_aqst_AtTheMarketOfferingMember_01a0eef3-16e0-7639-adcc-c1ea1d12d911" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PublicEquityOfferingMember_01a1196a-8231-7da8-b698-d37c4e383f43" xlink:href="aqst-20260930.xsd#aqst_PublicEquityOfferingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-7407-8bdf-ba0531a0ee9c" xlink:to="loc_aqst_PublicEquityOfferingMember_01a1196a-8231-7da8-b698-d37c4e383f43" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_01a0eef3-16e0-75c6-85a1-97614b6bae6f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_01a0eef3-16e0-7255-871c-826eae7e29dd" xlink:to="loc_us-gaap_StatementLineItems_01a0eef3-16e0-75c6-85a1-97614b6bae6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_01a0eef3-16e0-75c6-85a1-97614b6bae6f" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_01a0eef3-16e0-7b8f-aa24-b7cd1133378a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_SharesOutstanding_01a0eef3-16e0-7b8f-aa24-b7cd1133378a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_01a0eef3-16e0-76e3-b241-e55486caa722" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockholdersEquity_01a0eef3-16e0-76e3-b241-e55486caa722" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_01a0eef3-16e0-7b71-81e7-74ab1d2fe1d1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_01a0eef3-16e0-7b71-81e7-74ab1d2fe1d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_01a0eef3-16e0-7150-8b0a-947b3f26f241" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_01a0eef3-16e0-7150-8b0a-947b3f26f241" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedOwnshareLendingArrangementIssuanceCosts_01a11967-14d1-7318-8b12-0f5b3ae7622a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedOwnshareLendingArrangementIssuanceCosts"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedOwnshareLendingArrangementIssuanceCosts_01a11967-14d1-7318-8b12-0f5b3ae7622a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_01a0eef3-16e0-766e-b93d-9a0dd54b9cdb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_01a0eef3-16e0-766e-b93d-9a0dd54b9cdb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ProceedsFromExerciseOfWarrantsNet_01a0eef3-16e0-7955-bf93-195fdfef6ac6" xlink:href="aqst-20260930.xsd#aqst_ProceedsFromExerciseOfWarrantsNet"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_aqst_ProceedsFromExerciseOfWarrantsNet_01a0eef3-16e0-7955-bf93-195fdfef6ac6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued_01a0eef3-16e0-7f08-af33-dee625f23890" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued_01a0eef3-16e0-7f08-af33-dee625f23890" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_01a0eef3-16e0-795c-a4f4-5c909d3dfdbc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_01a0eef3-16e0-795c-a4f4-5c909d3dfdbc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_01a0eef3-16e0-77b9-8b03-1dca759e73af" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_01a0eef3-16e0-77b9-8b03-1dca759e73af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_01a0eef3-16e0-7ec6-a8a3-90c03d7f3140" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_01a0eef3-16e0-7ec6-a8a3-90c03d7f3140" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_01a0eef3-16e0-7d1c-b9d5-7baf075737b6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_01a0eef3-16e0-7d1c-b9d5-7baf075737b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_01a0eef3-16e0-7f90-86fc-897b77abbff9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_01a0eef3-16e0-7f90-86fc-897b77abbff9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_01a0eef3-16e0-7bdb-900a-e72211b54b31" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_01a0eef3-16e0-7bdb-900a-e72211b54b31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_01a0eef3-16e0-7f3b-8a62-f07dea0eeb99" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_01a0eef3-16e0-7f3b-8a62-f07dea0eeb99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_StockIssuedDuringPeriodSharesWarrantsExercised_01a11961-3052-77c6-8c54-dc190121ae10" xlink:href="aqst-20260930.xsd#aqst_StockIssuedDuringPeriodSharesWarrantsExercised"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_aqst_StockIssuedDuringPeriodSharesWarrantsExercised_01a11961-3052-77c6-8c54-dc190121ae10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_StockIssuedDuringPeriodValueWarrantsExercised_01a11962-03d0-7b35-9277-294fbda7d080" xlink:href="aqst-20260930.xsd#aqst_StockIssuedDuringPeriodValueWarrantsExercised"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_aqst_StockIssuedDuringPeriodValueWarrantsExercised_01a11962-03d0-7b35-9277-294fbda7d080" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-772c-8bd0-f1dec2de0fb9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-772c-8bd0-f1dec2de0fb9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_01a0eef3-16e0-7740-b17e-94c0f739469d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_SharesOutstanding_01a0eef3-16e0-7740-b17e-94c0f739469d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_01a0eef3-16e0-7177-8567-a1069b1aeb22" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01a0eef3-16e0-7566-99b2-9c78b749a1a6" xlink:to="loc_us-gaap_StockholdersEquity_01a0eef3-16e0-7177-8567-a1069b1aeb22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CondensedStatementsofCashFlows" xlink:type="simple" xlink:href="aqst-20260930.xsd#CondensedStatementsofCashFlows"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CondensedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7bf8-8ef9-861495105a92" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-7a79-8eae-d389557d4d55" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7bf8-8ef9-861495105a92" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-7a79-8eae-d389557d4d55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-73fd-a745-79c78d2053a3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-7a79-8eae-d389557d4d55" xlink:to="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-73fd-a745-79c78d2053a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-7a79-8eae-d389557d4d55" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationAndAmortization_01a0eef3-16e0-7910-a6c3-edd6120b6116" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DepreciationAndAmortization"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:to="loc_us-gaap_DepreciationAndAmortization_01a0eef3-16e0-7910-a6c3-edd6120b6116" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_01a0eef3-16e0-7fd6-8941-bf92f8c6f2db" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:to="loc_us-gaap_ShareBasedCompensation_01a0eef3-16e0-7fd6-8941-bf92f8c6f2db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_01a0eef3-16e0-7297-9b40-abe62cf00568" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_01a0eef3-16e0-7297-9b40-abe62cf00568" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_IssuanceOfWarrantsForPurchaseAgreement_01a0eef3-16e0-7aca-8ab3-072c46b4da06" xlink:href="aqst-20260930.xsd#aqst_IssuanceOfWarrantsForPurchaseAgreement"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:to="loc_aqst_IssuanceOfWarrantsForPurchaseAgreement_01a0eef3-16e0-7aca-8ab3-072c46b4da06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_01a0eef3-16e0-790d-bc30-bcc7e4cc90e5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_01a0eef3-16e0-790d-bc30-bcc7e4cc90e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_01a0eef3-16e0-77ec-aba2-7ee3fcbaa876" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_01a0eef3-16e0-77ec-aba2-7ee3fcbaa876" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-715f-aba1-7536557a8160" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables_01a0eef3-16e0-78b3-8511-d132da808112" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables_01a0eef3-16e0-78b3-8511-d132da808112" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_01a0eef3-16e0-7e74-ae71-a811ec3c1782" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_01a0eef3-16e0-7e74-ae71-a811ec3c1782" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_01a0eef3-16e0-74df-b602-de50289f41d0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_01a0eef3-16e0-74df-b602-de50289f41d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_01a0eef3-16e0-7ea6-9b7e-013379abe8f7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_01a0eef3-16e0-7ea6-9b7e-013379abe8f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities_01a0eef3-16e0-71f6-b28e-de2c05d2d241" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities_01a0eef3-16e0-71f6-b28e-de2c05d2d241" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInDeferredRevenue_01a0eef3-16e0-7125-aef8-8286440612e0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInDeferredRevenue"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_01a0eef3-16e0-7a74-8c9e-c7c2994cb943" xlink:to="loc_us-gaap_IncreaseDecreaseInDeferredRevenue_01a0eef3-16e0-7125-aef8-8286440612e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a0eef3-16e0-7160-a86b-8222212041ed" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_01a0eef3-16e0-7a79-8eae-d389557d4d55" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_01a0eef3-16e0-7160-a86b-8222212041ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_01a0eef3-16e0-7364-8a83-d5dfea3b1152" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7bf8-8ef9-861495105a92" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_01a0eef3-16e0-7364-8a83-d5dfea3b1152" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_01a0eef3-16e0-7f52-82f3-7c6b1f863e97" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_01a0eef3-16e0-7364-8a83-d5dfea3b1152" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_01a0eef3-16e0-7f52-82f3-7c6b1f863e97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a0eef3-16e0-7495-aab9-24540adb6da5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_01a0eef3-16e0-7364-8a83-d5dfea3b1152" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_01a0eef3-16e0-7495-aab9-24540adb6da5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7bf8-8ef9-861495105a92" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ProceedsFromIssuanceOfPublicOfferingIssuanceOfWarrantsAndWarrantExercises_01a0eef3-16e0-7d18-9612-a597761d1420" xlink:href="aqst-20260930.xsd#aqst_ProceedsFromIssuanceOfPublicOfferingIssuanceOfWarrantsAndWarrantExercises"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_aqst_ProceedsFromIssuanceOfPublicOfferingIssuanceOfWarrantsAndWarrantExercises_01a0eef3-16e0-7d18-9612-a597761d1420" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfPrivatePlacement_01a11a68-e864-7b44-8445-5bf772cfa630" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfPrivatePlacement"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfPrivatePlacement_01a11a68-e864-7b44-8445-5bf772cfa630" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_01a0eef3-16e0-779f-9807-568173ada97e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_01a0eef3-16e0-779f-9807-568173ada97e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfWarrants_01a0eef3-16e0-71a6-99ae-8f844b084737" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfWarrants"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfWarrants_01a0eef3-16e0-71a6-99ae-8f844b084737" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans_01a0eef3-16e0-73e8-86e4-1bd8ff4e4033" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans_01a0eef3-16e0-73e8-86e4-1bd8ff4e4033" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_01a0eef3-16e0-7010-9f3e-bba990fa15f0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_01a0eef3-16e0-7010-9f3e-bba990fa15f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ProceedsFromExerciseOfWarrantsNet_01a11a66-c26e-7bc2-8300-9025ecc3d3a5" xlink:href="aqst-20260930.xsd#aqst_ProceedsFromExerciseOfWarrantsNet"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_aqst_ProceedsFromExerciseOfWarrantsNet_01a11a66-c26e-7bc2-8300-9025ecc3d3a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfDebt_01a0eef3-16e0-7610-b360-1f6e8660e880" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RepaymentsOfDebt"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_RepaymentsOfDebt_01a0eef3-16e0-7610-b360-1f6e8660e880" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PaymentsForExitFeeOnRetirementOfDebt_01a0eef3-16e0-7169-aa11-4b76bfdb6b60" xlink:href="aqst-20260930.xsd#aqst_PaymentsForExitFeeOnRetirementOfDebt"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_aqst_PaymentsForExitFeeOnRetirementOfDebt_01a0eef3-16e0-7169-aa11-4b76bfdb6b60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PremiumPaymentsToRetireDebt_01a0eef3-16e0-7cbc-a999-00b7d7066e00" xlink:href="aqst-20260930.xsd#aqst_PremiumPaymentsToRetireDebt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_aqst_PremiumPaymentsToRetireDebt_01a0eef3-16e0-7cbc-a999-00b7d7066e00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfFinancingCosts_01a0eef3-16e0-72ab-bef4-c429759144d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsOfFinancingCosts"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_PaymentsOfFinancingCosts_01a0eef3-16e0-72ab-bef4-c429759144d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_FinanceLeasePrincipalPaymentsAndPaymentsForRoyaltyObligations_01a177b5-8f2e-7c23-9b96-6746935f5467" xlink:href="aqst-20260930.xsd#aqst_FinanceLeasePrincipalPaymentsAndPaymentsForRoyaltyObligations"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_aqst_FinanceLeasePrincipalPaymentsAndPaymentsForRoyaltyObligations_01a177b5-8f2e-7c23-9b96-6746935f5467" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_01a0eef3-16e0-7c1b-b2e6-0f2859055bc2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_01a0eef3-16e0-7c1b-b2e6-0f2859055bc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a0eef3-16e0-7d62-a752-cc62e9605624" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_01a0eef3-16e0-75f6-b7c7-b88771b50e44" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_01a0eef3-16e0-7d62-a752-cc62e9605624" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_01a0eef3-16e0-76ef-9483-ff5c31aed317" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7bf8-8ef9-861495105a92" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_01a0eef3-16e0-76ef-9483-ff5c31aed317" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsAbstract_01a0eef3-16e0-7060-a2dd-86b7df34f1da" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RestrictedCashAndCashEquivalentsAbstract"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7bf8-8ef9-861495105a92" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsAbstract_01a0eef3-16e0-7060-a2dd-86b7df34f1da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_01a0eef3-16e0-7bfb-97ff-4c607274ecf4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsAbstract_01a0eef3-16e0-7060-a2dd-86b7df34f1da" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_01a0eef3-16e0-7bfb-97ff-4c607274ecf4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_01a0eef3-16e0-7293-80be-fdeffa4bce0d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsAbstract_01a0eef3-16e0-7060-a2dd-86b7df34f1da" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_01a0eef3-16e0-7293-80be-fdeffa4bce0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_01a0eef3-16e0-7221-897a-75a54a37acd3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7bf8-8ef9-861495105a92" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_01a0eef3-16e0-7221-897a-75a54a37acd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPaidNet_01a0eef3-16e0-7f33-a991-0cbf9dd5ef92" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestPaidNet"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_01a0eef3-16e0-7221-897a-75a54a37acd3" xlink:to="loc_us-gaap_InterestPaidNet_01a0eef3-16e0-7f33-a991-0cbf9dd5ef92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_01a0eef3-16e0-75ae-951c-950006df8552" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CapitalExpendituresIncurredButNotYetPaid"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_01a0eef3-16e0-7221-897a-75a54a37acd3" xlink:to="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_01a0eef3-16e0-75ae-951c-950006df8552" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CostsAssociatedWithAtTheMarketPublicEquityOfferingInAccountsPayable_01a11a66-e7fc-7fd1-bbe2-0d63a3f9b3da" xlink:href="aqst-20260930.xsd#aqst_CostsAssociatedWithAtTheMarketPublicEquityOfferingInAccountsPayable"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_01a0eef3-16e0-7221-897a-75a54a37acd3" xlink:to="loc_aqst_CostsAssociatedWithAtTheMarketPublicEquityOfferingInAccountsPayable_01a11a66-e7fc-7fd1-bbe2-0d63a3f9b3da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CondensedStatementsofCashFlowsParenthetical" xlink:type="simple" xlink:href="aqst-20260930.xsd#CondensedStatementsofCashFlowsParenthetical"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CondensedStatementsofCashFlowsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7584-847e-775984de5554" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_01a0eef3-16e0-7f42-ba68-0e787b850b84" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_01a0eef3-16e0-7584-847e-775984de5554" xlink:to="loc_us-gaap_StatementTable_01a0eef3-16e0-7f42-ba68-0e787b850b84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-746d-81ff-39b459b20e14" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_01a0eef3-16e0-7f42-ba68-0e787b850b84" xlink:to="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-746d-81ff-39b459b20e14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7717-b092-3ea00e2fcce6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-746d-81ff-39b459b20e14" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7717-b092-3ea00e2fcce6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-16e0-76cf-868a-832b52e5c6a7" xlink:href="aqst-20260930.xsd#aqst_SeniorSecuredNotes13.5DueNovember12028Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7717-b092-3ea00e2fcce6" xlink:to="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-16e0-76cf-868a-832b52e5c6a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-724e-a836-871559a3b3ee" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_01a0eef3-16e0-7f42-ba68-0e787b850b84" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-724e-a836-871559a3b3ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-78aa-a370-173837211386" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-724e-a836-871559a3b3ee" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-78aa-a370-173837211386" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_01a0eef3-16e0-77b1-9452-9f0d6f5b4632" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-78aa-a370-173837211386" xlink:to="loc_us-gaap_SeniorNotesMember_01a0eef3-16e0-77b1-9452-9f0d6f5b4632" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_01a0eef3-16e0-761b-81b7-731a77c93e63" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_01a0eef3-16e0-7f42-ba68-0e787b850b84" xlink:to="loc_us-gaap_StatementLineItems_01a0eef3-16e0-761b-81b7-731a77c93e63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-16e0-7bb3-9195-276b6514decf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_01a0eef3-16e0-761b-81b7-731a77c93e63" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-16e0-7bb3-9195-276b6514decf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CompanyOverviewandBasisofPresentation" xlink:type="simple" xlink:href="aqst-20260930.xsd#CompanyOverviewandBasisofPresentation"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CompanyOverviewandBasisofPresentation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_01a0eef3-16e0-7c7b-904b-4fcdd5972073" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureAndSignificantAccountingPoliciesTextBlock_01a0eef3-16e0-7633-ad37-7baee438b1a3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureAndSignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_01a0eef3-16e0-7c7b-904b-4fcdd5972073" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureAndSignificantAccountingPoliciesTextBlock_01a0eef3-16e0-7633-ad37-7baee438b1a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="aqst-20260930.xsd#SummaryofSignificantAccountingPolicies"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SummaryofSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_01a0eef3-16e0-7f56-97a4-2587956ba7a7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_01a0eef3-16e0-750a-a5ad-dfa5678bf6d3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_01a0eef3-16e0-7f56-97a4-2587956ba7a7" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_01a0eef3-16e0-750a-a5ad-dfa5678bf6d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RisksandUncertainties" xlink:type="simple" xlink:href="aqst-20260930.xsd#RisksandUncertainties"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RisksandUncertainties" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_01a0eef3-16e0-7eaf-bb71-9f3dc2d114ec" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RisksAndUncertaintiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_01a0eef3-16e0-7524-b0f7-be21824196d2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_01a0eef3-16e0-7eaf-bb71-9f3dc2d114ec" xlink:to="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_01a0eef3-16e0-7524-b0f7-be21824196d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SegmentReporting" xlink:type="simple" xlink:href="aqst-20260930.xsd#SegmentReporting"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SegmentReporting" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-7a13-aa5e-edae0ac6468d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingDisclosureTextBlock_01a0eef3-16e0-7653-9b1f-6620e996fe89" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-7a13-aa5e-edae0ac6468d" xlink:to="loc_us-gaap_SegmentReportingDisclosureTextBlock_01a0eef3-16e0-7653-9b1f-6620e996fe89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RevenuesandTradeReceivablesNet" xlink:type="simple" xlink:href="aqst-20260930.xsd#RevenuesandTradeReceivablesNet"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RevenuesandTradeReceivablesNet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-757c-90fb-d5488cdc0c8e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_01a0eef3-16e0-7d15-bed0-e4d4b0d70aa4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-757c-90fb-d5488cdc0c8e" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerTextBlock_01a0eef3-16e0-7d15-bed0-e4d4b0d70aa4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/MaterialAgreements" xlink:type="simple" xlink:href="aqst-20260930.xsd#MaterialAgreements"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/MaterialAgreements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-16e0-7aa8-8e31-3bc0330359eb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_01a0eef3-16e0-7d25-bf00-2d366dc4d47b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-16e0-7aa8-8e31-3bc0330359eb" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_01a0eef3-16e0-7d25-bf00-2d366dc4d47b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/FinancialInstrumentsFairValueMeasurements" xlink:type="simple" xlink:href="aqst-20260930.xsd#FinancialInstrumentsFairValueMeasurements"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/FinancialInstrumentsFairValueMeasurements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_01a0eef3-16e0-7158-a622-7f41552db279" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_01a0eef3-16e0-7feb-8bdf-f7a73d480387" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueDisclosuresTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_01a0eef3-16e0-7158-a622-7f41552db279" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_01a0eef3-16e0-7feb-8bdf-f7a73d480387" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/InventoriesNet" xlink:type="simple" xlink:href="aqst-20260930.xsd#InventoriesNet"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/InventoriesNet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7f90-9216-cfa1c7404f20" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureTextBlock_01a0eef3-177f-7b43-9635-0599b7be6343" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7f90-9216-cfa1c7404f20" xlink:to="loc_us-gaap_InventoryDisclosureTextBlock_01a0eef3-177f-7b43-9635-0599b7be6343" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/PropertyandEquipmentNet" xlink:type="simple" xlink:href="aqst-20260930.xsd#PropertyandEquipmentNet"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/PropertyandEquipmentNet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-7f39-8f5d-593bce61b498" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_01a0eef3-177f-7dd5-b72c-98b2d8cc6e29" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-7f39-8f5d-593bce61b498" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_01a0eef3-177f-7dd5-b72c-98b2d8cc6e29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RightofUseAssetsandLeaseObligations" xlink:type="simple" xlink:href="aqst-20260930.xsd#RightofUseAssetsandLeaseObligations"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RightofUseAssetsandLeaseObligations" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7a31-abfa-499e839579ad" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_01a0eef3-177f-75cc-990f-159e25099609" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeasesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7a31-abfa-499e839579ad" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_01a0eef3-177f-75cc-990f-159e25099609" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNoncurrentAssets" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNoncurrentAssets"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNoncurrentAssets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7600-9fd0-5169638d7e70" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsDisclosureTextBlock_01a0eef3-177f-720d-92f1-e47d7972da7c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAssetsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7600-9fd0-5169638d7e70" xlink:to="loc_us-gaap_OtherAssetsDisclosureTextBlock_01a0eef3-177f-720d-92f1-e47d7972da7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/AccruedExpenses" xlink:type="simple" xlink:href="aqst-20260930.xsd#AccruedExpenses"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/AccruedExpenses" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_01a0eef3-177f-74db-ad8e-2f962b3a7b28" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PayablesAndAccrualsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_01a0eef3-177f-70d9-9b6a-664811ab6bf9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_01a0eef3-177f-74db-ad8e-2f962b3a7b28" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_01a0eef3-177f-70d9-9b6a-664811ab6bf9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/LongTermDebt" xlink:type="simple" xlink:href="aqst-20260930.xsd#LongTermDebt"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/LongTermDebt" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-702d-af66-793487b247f5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_01a0eef3-177f-7f6e-881b-d563cbafd6af" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-702d-af66-793487b247f5" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_01a0eef3-177f-7f6e-881b-d563cbafd6af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/Warrants" xlink:type="simple" xlink:href="aqst-20260930.xsd#Warrants"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/Warrants" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsNoteDisclosureAbstract_01a0eef3-177f-7bac-a4a4-b02898209428" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WarrantsAndRightsNoteDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_WarrantsDisclosureTextBlock_01a0eef3-177f-72b3-8915-925f0116e4f0" xlink:href="aqst-20260930.xsd#aqst_WarrantsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WarrantsAndRightsNoteDisclosureAbstract_01a0eef3-177f-7bac-a4a4-b02898209428" xlink:to="loc_aqst_WarrantsDisclosureTextBlock_01a0eef3-177f-72b3-8915-925f0116e4f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SaleofFutureRevenue" xlink:type="simple" xlink:href="aqst-20260930.xsd#SaleofFutureRevenue"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SaleofFutureRevenue" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-7218-873e-4519b756a894" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SaleOfFutureRevenueTextBlock_01a0eef3-177f-7414-a138-9b50d0ce7e5a" xlink:href="aqst-20260930.xsd#aqst_SaleOfFutureRevenueTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-7218-873e-4519b756a894" xlink:to="loc_aqst_SaleOfFutureRevenueTextBlock_01a0eef3-177f-7414-a138-9b50d0ce7e5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNonCurrentLiabilities" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNonCurrentLiabilities"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNonCurrentLiabilities" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-7940-9683-5a995f3baf86" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationDisclosureTextBlock_01a0eef3-177f-761b-9eda-d76e554cf3ce" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-7940-9683-5a995f3baf86" xlink:to="loc_us-gaap_AssetRetirementObligationDisclosureTextBlock_01a0eef3-177f-761b-9eda-d76e554cf3ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/NetLossPerShare" xlink:type="simple" xlink:href="aqst-20260930.xsd#NetLossPerShare"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/NetLossPerShare" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-177f-75f6-85f8-057de9cd9e06" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_01a0eef3-177f-705c-9a38-588939360f98" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-177f-75f6-85f8-057de9cd9e06" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_01a0eef3-177f-705c-9a38-588939360f98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ShareBasedCompensation" xlink:type="simple" xlink:href="aqst-20260930.xsd#ShareBasedCompensation"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ShareBasedCompensation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7875-88be-b5eb591788c9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_01a0eef3-177f-779e-8c3a-8c4de9d4a256" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7875-88be-b5eb591788c9" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_01a0eef3-177f-779e-8c3a-8c4de9d4a256" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/IncomeTaxes" xlink:type="simple" xlink:href="aqst-20260930.xsd#IncomeTaxes"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_01a0eef3-1780-7d50-83e6-de08863c117d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_01a0eef3-1780-7be3-b486-ded2837537fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_01a0eef3-1780-7d50-83e6-de08863c117d" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_01a0eef3-1780-7be3-b486-ded2837537fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/Contingencies" xlink:type="simple" xlink:href="aqst-20260930.xsd#Contingencies"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/Contingencies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_01a0eef3-1780-7106-8637-a118c641d744" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_01a0eef3-1780-7b78-ad6d-b92022fccbb3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_01a0eef3-1780-7106-8637-a118c641d744" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_01a0eef3-1780-7b78-ad6d-b92022fccbb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SubsequentEvents" xlink:type="simple" xlink:href="aqst-20260930.xsd#SubsequentEvents"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SubsequentEvents" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_01a0eef3-1780-73d3-b80a-6deae202c8f6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_01a0eef3-1780-7fe9-921d-21f21f6be5b0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_01a0eef3-1780-73d3-b80a-6deae202c8f6" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_01a0eef3-1780-7fe9-921d-21f21f6be5b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="aqst-20260930.xsd#SummaryofSignificantAccountingPoliciesPolicies"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_01a0eef3-16e0-7580-8e7e-fc1e37f4808c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_01a0eef3-16e0-7c8b-949d-061dde5e3c3c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_01a0eef3-16e0-7580-8e7e-fc1e37f4808c" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_01a0eef3-16e0-7c8b-949d-061dde5e3c3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_01a0eef3-16e0-7c84-ba4a-a8d4dc3734f5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_01a0eef3-16e0-7580-8e7e-fc1e37f4808c" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_01a0eef3-16e0-7c84-ba4a-a8d4dc3734f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_01a0eef3-16e0-7ca9-a01d-6376c99c1300" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_01a0eef3-16e0-7580-8e7e-fc1e37f4808c" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_01a0eef3-16e0-7ca9-a01d-6376c99c1300" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SegmentReportingTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#SegmentReportingTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SegmentReportingTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-7db8-a745-416c46e3a017" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_01a0eef3-16e0-7cf4-9ae8-01ee2ea7d602" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-7db8-a745-416c46e3a017" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock_01a0eef3-16e0-7cf4-9ae8-01ee2ea7d602" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RevenuesandTradeReceivablesNetTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#RevenuesandTradeReceivablesNetTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RevenuesandTradeReceivablesNetTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-74bf-8623-957de3b0c6ef" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTextBlock_01a0eef3-16e0-7eba-9dbf-3a7bbb6dd70b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-74bf-8623-957de3b0c6ef" xlink:to="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTextBlock_01a0eef3-16e0-7eba-9dbf-3a7bbb6dd70b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_01a0eef3-16e0-76b0-b597-a716624d3657" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-74bf-8623-957de3b0c6ef" xlink:to="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_01a0eef3-16e0-76b0-b597-a716624d3657" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_01a0eef3-16e0-7d8c-806d-1893e1f11549" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-74bf-8623-957de3b0c6ef" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_01a0eef3-16e0-7d8c-806d-1893e1f11549" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ScheduleOfAccountsReceivableAllowancesTableTextBlock_01a0eef3-16e0-75f3-af75-d7e304d50e9a" xlink:href="aqst-20260930.xsd#aqst_ScheduleOfAccountsReceivableAllowancesTableTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-74bf-8623-957de3b0c6ef" xlink:to="loc_aqst_ScheduleOfAccountsReceivableAllowancesTableTextBlock_01a0eef3-16e0-75f3-af75-d7e304d50e9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/InventoriesNetTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#InventoriesNetTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/InventoriesNetTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7c5c-a400-690978cebbbe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_01a0eef3-177f-7cfc-af3e-d2ad980b7c88" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7c5c-a400-690978cebbbe" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_01a0eef3-177f-7cfc-af3e-d2ad980b7c88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/PropertyandEquipmentNetTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#PropertyandEquipmentNetTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/PropertyandEquipmentNetTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-7742-b66f-f9d527fc7517" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_01a0eef3-177f-773d-8a04-30e5fcd967f6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-7742-b66f-f9d527fc7517" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_01a0eef3-177f-773d-8a04-30e5fcd967f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RightofUseAssetsandLeaseObligationsTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#RightofUseAssetsandLeaseObligationsTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RightofUseAssetsandLeaseObligationsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7cbb-9bca-3f7f12b753c4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_01a0eef3-177f-7b96-99b3-da635535c6af" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7cbb-9bca-3f7f12b753c4" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_01a0eef3-177f-7b96-99b3-da635535c6af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNoncurrentAssetsTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNoncurrentAssetsTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNoncurrentAssetsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7139-8af7-90d711ed0061" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfOtherAssetsNoncurrentTextBlock_01a0eef3-177f-7dff-97da-511a1019a245" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfOtherAssetsNoncurrentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7139-8af7-90d711ed0061" xlink:to="loc_us-gaap_ScheduleOfOtherAssetsNoncurrentTextBlock_01a0eef3-177f-7dff-97da-511a1019a245" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/AccruedExpensesTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#AccruedExpensesTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/AccruedExpensesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_01a0eef3-177f-74c5-a6e0-4f3c718f0da4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PayablesAndAccrualsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_01a0eef3-177f-737a-992e-da39ecbf810c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_01a0eef3-177f-74c5-a6e0-4f3c718f0da4" xlink:to="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_01a0eef3-177f-737a-992e-da39ecbf810c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/LongTermDebtTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#LongTermDebtTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/LongTermDebtTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-70f2-9bef-368707c18d37" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ScheduleOfSignificantUnobservableInputsUsedInTheInitialFairValueMeasurementOfTheRoyaltyRightAgreementTableTextBlock_01a0eef3-177f-7689-8517-b1d59a7266b4" xlink:href="aqst-20260930.xsd#aqst_ScheduleOfSignificantUnobservableInputsUsedInTheInitialFairValueMeasurementOfTheRoyaltyRightAgreementTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-70f2-9bef-368707c18d37" xlink:to="loc_aqst_ScheduleOfSignificantUnobservableInputsUsedInTheInitialFairValueMeasurementOfTheRoyaltyRightAgreementTableTextBlock_01a0eef3-177f-7689-8517-b1d59a7266b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_01a0eef3-177f-75ef-a323-b944c7d91378" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-70f2-9bef-368707c18d37" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_01a0eef3-177f-75ef-a323-b944c7d91378" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_01a0eef3-177f-7e70-a748-325f1a4b3f28" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-70f2-9bef-368707c18d37" xlink:to="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_01a0eef3-177f-7e70-a748-325f1a4b3f28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SaleofFutureRevenueTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#SaleofFutureRevenueTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SaleofFutureRevenueTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-7525-a98d-bf331aae65fe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationActivityTableTextBlock_01a0eef3-177f-7661-9b4f-ca3f3a416af8" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationActivityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-7525-a98d-bf331aae65fe" xlink:to="loc_aqst_RoyaltyObligationActivityTableTextBlock_01a0eef3-177f-7661-9b4f-ca3f3a416af8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNonCurrentLiabilitiesTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNonCurrentLiabilitiesTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNonCurrentLiabilitiesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-773d-9917-ab61ddc7871a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAssetRetirementObligationsTableTextBlock_01a0eef3-177f-7f0d-bc70-eb1397eafa71" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfAssetRetirementObligationsTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-773d-9917-ab61ddc7871a" xlink:to="loc_us-gaap_ScheduleOfAssetRetirementObligationsTableTextBlock_01a0eef3-177f-7f0d-bc70-eb1397eafa71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/NetLossPerShareTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#NetLossPerShareTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/NetLossPerShareTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-177f-7aca-9ba9-80e34a0aa1b3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_01a0eef3-177f-75c5-8a6f-96cc4f8bfe7d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-177f-7aca-9ba9-80e34a0aa1b3" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_01a0eef3-177f-75c5-8a6f-96cc4f8bfe7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ShareBasedCompensationTables" xlink:type="simple" xlink:href="aqst-20260930.xsd#ShareBasedCompensationTables"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ShareBasedCompensationTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7220-a834-ccd91b84ecc7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock_01a0eef3-177f-7499-b333-e8d78a353e0a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7220-a834-ccd91b84ecc7" xlink:to="loc_us-gaap_ScheduleOfCompensationCostForShareBasedPaymentArrangementsAllocationOfShareBasedCompensationCostsByPlanTableTextBlock_01a0eef3-177f-7499-b333-e8d78a353e0a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonvestedRestrictedStockSharesActivityTableTextBlock_01a0eef3-177f-7846-9d80-1c564b59a2cf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NonvestedRestrictedStockSharesActivityTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7220-a834-ccd91b84ecc7" xlink:to="loc_us-gaap_NonvestedRestrictedStockSharesActivityTableTextBlock_01a0eef3-177f-7846-9d80-1c564b59a2cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_01a0eef3-177f-757d-b741-85224581184b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7220-a834-ccd91b84ecc7" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_01a0eef3-177f-757d-b741-85224581184b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_01a0eef3-177f-7062-9419-e6e4120f179f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7220-a834-ccd91b84ecc7" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_01a0eef3-177f-7062-9419-e6e4120f179f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/CompanyOverviewandBasisofPresentationDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#CompanyOverviewandBasisofPresentationDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/CompanyOverviewandBasisofPresentationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_01a0eef3-16e0-74c1-ba94-12085c9cac5f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_01a0eef3-16e0-7ad8-9bbe-ddbebd20cb9b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_01a0eef3-16e0-74c1-ba94-12085c9cac5f" xlink:to="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_01a0eef3-16e0-7ad8-9bbe-ddbebd20cb9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-74b3-a501-742256c3d97b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_01a0eef3-16e0-7ad8-9bbe-ddbebd20cb9b" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-74b3-a501-742256c3d97b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-71a7-8833-fbc027f62a8c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-74b3-a501-742256c3d97b" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-71a7-8833-fbc027f62a8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_EquityDistributionAgreementMember_01a0eef3-16e0-7354-b4d2-422c2f9f0e0c" xlink:href="aqst-20260930.xsd#aqst_EquityDistributionAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-71a7-8833-fbc027f62a8c" xlink:to="loc_aqst_EquityDistributionAgreementMember_01a0eef3-16e0-7354-b4d2-422c2f9f0e0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AmendedEquityDistributionAgreementMember_01a0eef3-16e0-7da4-9f40-26c83b12276c" xlink:href="aqst-20260930.xsd#aqst_AmendedEquityDistributionAgreementMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-71a7-8833-fbc027f62a8c" xlink:to="loc_aqst_AmendedEquityDistributionAgreementMember_01a0eef3-16e0-7da4-9f40-26c83b12276c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_UnderwrittenPublicOfferingMember_01a0eef3-16e0-7648-9ebe-2cb9bbeedd8b" xlink:href="aqst-20260930.xsd#aqst_UnderwrittenPublicOfferingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-71a7-8833-fbc027f62a8c" xlink:to="loc_aqst_UnderwrittenPublicOfferingMember_01a0eef3-16e0-7648-9ebe-2cb9bbeedd8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-16e0-7563-8b6b-e46a64a38e84" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_01a0eef3-16e0-7ad8-9bbe-ddbebd20cb9b" xlink:to="loc_srt_RangeAxis_01a0eef3-16e0-7563-8b6b-e46a64a38e84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-16e0-73ea-b9dc-85e469ea6ae8" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-16e0-7563-8b6b-e46a64a38e84" xlink:to="loc_srt_RangeMember_01a0eef3-16e0-73ea-b9dc-85e469ea6ae8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-16e0-7092-a8c5-2be305e3f28c" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-16e0-73ea-b9dc-85e469ea6ae8" xlink:to="loc_srt_MaximumMember_01a0eef3-16e0-7092-a8c5-2be305e3f28c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsidiarySaleOfStockLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_01a0eef3-16e0-7ad8-9bbe-ddbebd20cb9b" xlink:to="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NumberOfProducts_01a0eef3-16e0-7297-b331-582f88f1a4b1" xlink:href="aqst-20260930.xsd#aqst_NumberOfProducts"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_aqst_NumberOfProducts_01a0eef3-16e0-7297-b331-582f88f1a4b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NumberOfMarketedGeographicAreas_01a0eef3-16e0-77b1-90dd-28584d0acdab" xlink:href="aqst-20260930.xsd#aqst_NumberOfMarketedGeographicAreas"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_aqst_NumberOfMarketedGeographicAreas_01a0eef3-16e0-77b1-90dd-28584d0acdab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_01a0eef3-16e0-7918-9ff5-31bdfe84cc71" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_01a0eef3-16e0-7918-9ff5-31bdfe84cc71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_01a0eef3-16e0-78e3-a3e6-68bb9d53c58d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_01a0eef3-16e0-78e3-a3e6-68bb9d53c58d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_01a0eef3-16e0-7f0c-a788-8cb372366161" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsOfStockIssuanceCosts"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_01a0eef3-16e0-7f0c-a788-8cb372366161" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SaleOfStockMaximumTransactionAmount_01a0eef3-16e0-7899-bd50-a2a0c5ac9877" xlink:href="aqst-20260930.xsd#aqst_SaleOfStockMaximumTransactionAmount"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_aqst_SaleOfStockMaximumTransactionAmount_01a0eef3-16e0-7899-bd50-a2a0c5ac9877" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SaleOfStockAggregateOfferingPrice_01a0eef3-16e0-74d1-bc02-cf59010cae8a" xlink:href="aqst-20260930.xsd#aqst_SaleOfStockAggregateOfferingPrice"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_aqst_SaleOfStockAggregateOfferingPrice_01a0eef3-16e0-74d1-bc02-cf59010cae8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SaleOfStockConsiderationReceivedOnTransactionUnderwritingDiscounts_01a0eef3-16e0-773b-80a3-6034f13b25c2" xlink:href="aqst-20260930.xsd#aqst_SaleOfStockConsiderationReceivedOnTransactionUnderwritingDiscounts"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_aqst_SaleOfStockConsiderationReceivedOnTransactionUnderwritingDiscounts_01a0eef3-16e0-773b-80a3-6034f13b25c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_01a0eef3-16e0-75c8-84cc-0bfdc97d70ed" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_01a0eef3-16e0-75c8-84cc-0bfdc97d70ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_01a0eef3-16e0-7724-b8d2-49b80b06b8d6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SaleOfStockPricePerShare"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_01a0eef3-16e0-72be-9611-f88054a9de3f" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_01a0eef3-16e0-7724-b8d2-49b80b06b8d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RisksandUncertaintiesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RisksandUncertaintiesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RisksandUncertaintiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_01a0eef3-16e0-7032-913c-aec7ef8dba3d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RisksAndUncertaintiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_01a0eef3-16e0-7ea9-9bc9-6fc24ee6ab8b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_01a0eef3-16e0-7032-913c-aec7ef8dba3d" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_01a0eef3-16e0-7ea9-9bc9-6fc24ee6ab8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_01a0eef3-16e0-7aa9-842f-30814393a472" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_01a0eef3-16e0-7032-913c-aec7ef8dba3d" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_01a0eef3-16e0-7aa9-842f-30814393a472" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SegmentReportingNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#SegmentReportingNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SegmentReportingNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-72b0-b3ae-bfdd6d21cade" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_01a0eef3-16e0-7691-b2f1-b1e898f58a85" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-72b0-b3ae-bfdd6d21cade" xlink:to="loc_us-gaap_NumberOfOperatingSegments_01a0eef3-16e0-7691-b2f1-b1e898f58a85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfReportableSegments_01a0eef3-16e0-7ffc-aff9-3ba6bae3d0c4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NumberOfReportableSegments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-72b0-b3ae-bfdd6d21cade" xlink:to="loc_us-gaap_NumberOfReportableSegments_01a0eef3-16e0-7ffc-aff9-3ba6bae3d0c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NumberOfProducts_01a0eef3-16e0-79df-83a5-3ae4df0fcff9" xlink:href="aqst-20260930.xsd#aqst_NumberOfProducts"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-72b0-b3ae-bfdd6d21cade" xlink:to="loc_aqst_NumberOfProducts_01a0eef3-16e0-79df-83a5-3ae4df0fcff9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7734-986c-693132406b02" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-72b0-b3ae-bfdd6d21cade" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7734-986c-693132406b02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SegmentReportingScheduleofSegmentReportingInformationbySegmentDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#SegmentReportingScheduleofSegmentReportingInformationbySegmentDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SegmentReportingScheduleofSegmentReportingInformationbySegmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-7871-b853-a3f5ed273a10" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_01a0eef3-16e0-7538-a6b1-28e838e01eea" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_01a0eef3-16e0-7871-b853-a3f5ed273a10" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_01a0eef3-16e0-7538-a6b1-28e838e01eea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_01a0eef3-16e0-7976-a52c-005435ec8d8f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_01a0eef3-16e0-7538-a6b1-28e838e01eea" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_01a0eef3-16e0-7976-a52c-005435ec8d8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_01a0eef3-16e0-78b5-ab43-2abf88b214f0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_01a0eef3-16e0-7976-a52c-005435ec8d8f" xlink:to="loc_us-gaap_SegmentDomain_01a0eef3-16e0-78b5-ab43-2abf88b214f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ReportableSegmentMember_01a0eef3-16e0-75c5-bcf1-21823db6efb4" xlink:href="aqst-20260930.xsd#aqst_ReportableSegmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentDomain_01a0eef3-16e0-78b5-ab43-2abf88b214f0" xlink:to="loc_aqst_ReportableSegmentMember_01a0eef3-16e0-75c5-bcf1-21823db6efb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7de9-b6f7-cf66576d15af" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_01a0eef3-16e0-7538-a6b1-28e838e01eea" xlink:to="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7de9-b6f7-cf66576d15af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7a8e-bf0e-14eaa5a60ccf" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7de9-b6f7-cf66576d15af" xlink:to="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7a8e-bf0e-14eaa5a60ccf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AnaphylmMember_01a0eef3-16e0-77e4-906c-bcbc5dd9f22c" xlink:href="aqst-20260930.xsd#aqst_AnaphylmMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7a8e-bf0e-14eaa5a60ccf" xlink:to="loc_aqst_AnaphylmMember_01a0eef3-16e0-77e4-906c-bcbc5dd9f22c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AQST108Member_01a0eef3-16e0-7e14-84ab-678555c62b4a" xlink:href="aqst-20260930.xsd#aqst_AQST108Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7a8e-bf0e-14eaa5a60ccf" xlink:to="loc_aqst_AQST108Member_01a0eef3-16e0-7e14-84ab-678555c62b4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PersonnelCostsMember_01a0eef3-16e0-7ef4-b1bc-f6a2e231af44" xlink:href="aqst-20260930.xsd#aqst_PersonnelCostsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7a8e-bf0e-14eaa5a60ccf" xlink:to="loc_aqst_PersonnelCostsMember_01a0eef3-16e0-7ef4-b1bc-f6a2e231af44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OtherMember_01a0eef3-16e0-723a-8b50-b9afabde10a9" xlink:href="aqst-20260930.xsd#aqst_OtherMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7a8e-bf0e-14eaa5a60ccf" xlink:to="loc_aqst_OtherMember_01a0eef3-16e0-723a-8b50-b9afabde10a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SegmentReportingInformationLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_01a0eef3-16e0-7538-a6b1-28e838e01eea" xlink:to="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-78b5-a4e7-26417deb8c72" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-78b5-a4e7-26417deb8c72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_01a0eef3-16e0-7638-b88d-65c7569b27ae" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServicesSoldAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_01a0eef3-16e0-7638-b88d-65c7569b27ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_01a0eef3-16e0-7ae5-9125-c9060e9b2cc0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_01a0eef3-16e0-7638-b88d-65c7569b27ae" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_01a0eef3-16e0-7ae5-9125-c9060e9b2cc0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_01a0eef3-16e0-7ba3-844e-b63a981041e7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_01a0eef3-16e0-7638-b88d-65c7569b27ae" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_01a0eef3-16e0-7ba3-844e-b63a981041e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpenseAbstract_01a0eef3-16e0-7c08-8c81-9b98c80985f9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SellingGeneralAndAdministrativeExpenseAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpenseAbstract_01a0eef3-16e0-7c08-8c81-9b98c80985f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingExpense_01a0eef3-16e0-7473-bfd1-70f8bea48c1b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SellingExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SellingGeneralAndAdministrativeExpenseAbstract_01a0eef3-16e0-7c08-8c81-9b98c80985f9" xlink:to="loc_us-gaap_SellingExpense_01a0eef3-16e0-7473-bfd1-70f8bea48c1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseAbstract_01a0eef3-16e0-71e3-b9a3-cec1179ab482" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GeneralAndAdministrativeExpenseAbstract"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseAbstract_01a0eef3-16e0-71e3-b9a3-cec1179ab482" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_01a0eef3-16e0-77a1-bdc3-c9ef15ad943c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GeneralAndAdministrativeExpenseAbstract_01a0eef3-16e0-71e3-b9a3-cec1179ab482" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_01a0eef3-16e0-77a1-bdc3-c9ef15ad943c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_01a0eef3-16e0-7f79-bdbe-7dac67df68c4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_01a0eef3-16e0-7f79-bdbe-7dac67df68c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_01a0eef3-16e0-77b3-bca2-2291f0011bda" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostsAndExpenses"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_CostsAndExpenses_01a0eef3-16e0-77b3-bca2-2291f0011bda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_01a0eef3-16e0-7b7d-862c-48a92b47d591" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_OperatingIncomeLoss_01a0eef3-16e0-7b7d-862c-48a92b47d591" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_01a0eef3-16e0-75e5-ad62-8339fad81068" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_01a0eef3-16e0-75e5-ad62-8339fad81068" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a0eef3-16e0-7c72-97a7-0051402a0a46" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a0eef3-16e0-7c72-97a7-0051402a0a46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-75c0-a8fe-b8cec808d2cc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_NetIncomeLoss_01a0eef3-16e0-75c0-a8fe-b8cec808d2cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_01a0eef3-16e0-7cc0-8809-b01a6f8fa9df" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_01a0eef3-16e0-74a7-9114-d5f31d26ee2d" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_01a0eef3-16e0-7cc0-8809-b01a6f8fa9df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RevenuesandTradeReceivablesNetNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RevenuesandTradeReceivablesNetNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RevenuesandTradeReceivablesNetNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-783c-9cb0-82bb9ca3c404" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-783c-9cb0-82bb9ca3c404" xlink:to="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-16e0-75ba-bb42-98c8d760791e" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:to="loc_srt_RangeAxis_01a0eef3-16e0-75ba-bb42-98c8d760791e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-16e0-79f1-ad23-b56596bcc496" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-16e0-75ba-bb42-98c8d760791e" xlink:to="loc_srt_RangeMember_01a0eef3-16e0-79f1-ad23-b56596bcc496" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-16e0-7781-9904-579dccc69c37" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-16e0-79f1-ad23-b56596bcc496" xlink:to="loc_srt_MaximumMember_01a0eef3-16e0-7781-9904-579dccc69c37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-16e0-7265-b06f-b74c10a8dd40" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:to="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-16e0-7265-b06f-b74c10a8dd40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7902-afce-f2cbec9f7ac5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReceivableTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-16e0-7265-b06f-b74c10a8dd40" xlink:to="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7902-afce-f2cbec9f7ac5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TradeAccountsReceivableDoubtfulAccountsMember_01a0eef3-16e0-7207-b496-1ac8bb67deb9" xlink:href="aqst-20260930.xsd#aqst_TradeAccountsReceivableDoubtfulAccountsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7902-afce-f2cbec9f7ac5" xlink:to="loc_aqst_TradeAccountsReceivableDoubtfulAccountsMember_01a0eef3-16e0-7207-b496-1ac8bb67deb9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TradeAccountsReceivableMember_01a0eef3-16e0-7be5-a8ea-c04ee6727f26" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TradeAccountsReceivableMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7902-afce-f2cbec9f7ac5" xlink:to="loc_us-gaap_TradeAccountsReceivableMember_01a0eef3-16e0-7be5-a8ea-c04ee6727f26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OtherReceivablesAndAccruedExpensesMember_01a0eef3-16e0-71ab-9f62-b80f54a2c0a8" xlink:href="aqst-20260930.xsd#aqst_OtherReceivablesAndAccruedExpensesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7902-afce-f2cbec9f7ac5" xlink:to="loc_aqst_OtherReceivablesAndAccruedExpensesMember_01a0eef3-16e0-71ab-9f62-b80f54a2c0a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MajorCustomersAxis_01a0eef3-16e0-7381-9b24-41705f8a835a" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MajorCustomersAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:to="loc_srt_MajorCustomersAxis_01a0eef3-16e0-7381-9b24-41705f8a835a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_NameOfMajorCustomerDomain_01a0eef3-16e0-7175-9f63-85b48ccb4c62" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_NameOfMajorCustomerDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_01a0eef3-16e0-7381-9b24-41705f8a835a" xlink:to="loc_srt_NameOfMajorCustomerDomain_01a0eef3-16e0-7175-9f63-85b48ccb4c62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_IndiviorMember_01a0eef3-16e0-75d4-a22e-82f679e1bfeb" xlink:href="aqst-20260930.xsd#aqst_IndiviorMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_01a0eef3-16e0-7175-9f63-85b48ccb4c62" xlink:to="loc_aqst_IndiviorMember_01a0eef3-16e0-75d4-a22e-82f679e1bfeb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ZevraMember_01a0eef3-16e0-7c7f-93e8-461c98cbe8ef" xlink:href="aqst-20260930.xsd#aqst_ZevraMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_01a0eef3-16e0-7175-9f63-85b48ccb4c62" xlink:to="loc_aqst_ZevraMember_01a0eef3-16e0-7c7f-93e8-461c98cbe8ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_HyperaMember_01a0eef3-16e0-7bd3-9f2f-677e9875157c" xlink:href="aqst-20260930.xsd#aqst_HyperaMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_01a0eef3-16e0-7175-9f63-85b48ccb4c62" xlink:to="loc_aqst_HyperaMember_01a0eef3-16e0-7bd3-9f2f-677e9875157c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CosetteMember_01a17610-f9ff-7c10-a555-c7280d7db083" xlink:href="aqst-20260930.xsd#aqst_CosetteMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_01a0eef3-16e0-7175-9f63-85b48ccb4c62" xlink:to="loc_aqst_CosetteMember_01a17610-f9ff-7c10-a555-c7280d7db083" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_01a0eef3-16e0-73b4-916a-47bd704aa634" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_01a0eef3-16e0-73b4-916a-47bd704aa634" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_01a0eef3-16e0-72fa-a143-6d0262d1d292" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_01a0eef3-16e0-73b4-916a-47bd704aa634" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_01a0eef3-16e0-72fa-a143-6d0262d1d292" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerMember_01a0eef3-16e0-73f6-990d-4601aba3eaf6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_01a0eef3-16e0-72fa-a143-6d0262d1d292" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerMember_01a0eef3-16e0-73f6-990d-4601aba3eaf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableMember_01a0eef3-16e0-7021-86a5-d52e991d2fd0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsReceivableMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_01a0eef3-16e0-72fa-a143-6d0262d1d292" xlink:to="loc_us-gaap_AccountsReceivableMember_01a0eef3-16e0-7021-86a5-d52e991d2fd0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_01a0eef3-16e0-700b-b0b7-0f508150da18" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskByTypeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_01a0eef3-16e0-700b-b0b7-0f508150da18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_01a0eef3-16e0-70b6-9bbf-03361491c635" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_01a0eef3-16e0-700b-b0b7-0f508150da18" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_01a0eef3-16e0-70b6-9bbf-03361491c635" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerConcentrationRiskMember_01a0eef3-16e0-7a20-9322-c03eb8fde7ee" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CustomerConcentrationRiskMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_01a0eef3-16e0-70b6-9bbf-03361491c635" xlink:to="loc_us-gaap_CustomerConcentrationRiskMember_01a0eef3-16e0-7a20-9322-c03eb8fde7ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_01a0eef3-16e0-7935-9932-3f1695d640ab" xlink:to="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ResearchAndDevelopmentProjectDuration_01a0eef3-16e0-78e6-afe6-05d66b22303e" xlink:href="aqst-20260930.xsd#aqst_ResearchAndDevelopmentProjectDuration"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:to="loc_aqst_ResearchAndDevelopmentProjectDuration_01a0eef3-16e0-78e6-afe6-05d66b22303e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerAssetNet_01a0eef3-16e0-7bee-aeec-d56183eac425" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ContractWithCustomerAssetNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:to="loc_us-gaap_ContractWithCustomerAssetNet_01a0eef3-16e0-7bee-aeec-d56183eac425" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiability_01a0eef3-16e0-7cfb-a1df-fd5ba54db0b0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ContractWithCustomerLiability"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:to="loc_us-gaap_ContractWithCustomerLiability_01a0eef3-16e0-7cfb-a1df-fd5ba54db0b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedContractCostNet_01a0eef3-16e0-7d9f-8f8e-d8dd2da89a08" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CapitalizedContractCostNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:to="loc_us-gaap_CapitalizedContractCostNet_01a0eef3-16e0-7d9f-8f8e-d8dd2da89a08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivablesGrossCurrent_01a0eef3-16e0-7220-883b-82c51bcf0732" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherReceivablesGrossCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:to="loc_us-gaap_OtherReceivablesGrossCurrent_01a0eef3-16e0-7220-883b-82c51bcf0732" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-16e0-7b83-94d6-21b18030e535" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-16e0-7b83-94d6-21b18030e535" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_01a0eef3-16e0-7697-b499-65d199bc536b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConcentrationRiskPercentage1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_01a0eef3-16e0-77e2-b791-35824fb75e27" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_01a0eef3-16e0-7697-b499-65d199bc536b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofRevenueDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RevenuesandTradeReceivablesNetScheduleofRevenueDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofRevenueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-7978-a31d-9fbf8695a25b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-773a-8df2-f1725daf33d5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-7978-a31d-9fbf8695a25b" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-773a-8df2-f1725daf33d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7b57-be29-c3429ff918de" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-773a-8df2-f1725daf33d5" xlink:to="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7b57-be29-c3429ff918de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-75bb-b862-5b237d5c04b7" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7b57-be29-c3429ff918de" xlink:to="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-75bb-b862-5b237d5c04b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ManufactureAndSupplyRevenueMember_01a0eef3-16e0-7b71-a730-114bf0309d9e" xlink:href="aqst-20260930.xsd#aqst_ManufactureAndSupplyRevenueMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-75bb-b862-5b237d5c04b7" xlink:to="loc_aqst_ManufactureAndSupplyRevenueMember_01a0eef3-16e0-7b71-a730-114bf0309d9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAndRoyaltyRevenueMember_01a0eef3-16e0-701c-898d-92958f4b2e27" xlink:href="aqst-20260930.xsd#aqst_LicenseAndRoyaltyRevenueMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-75bb-b862-5b237d5c04b7" xlink:to="loc_aqst_LicenseAndRoyaltyRevenueMember_01a0eef3-16e0-701c-898d-92958f4b2e27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CoDevelopmentAndResearchFeesMember_01a0eef3-16e0-7e69-bfcf-edb91153f5fb" xlink:href="aqst-20260930.xsd#aqst_CoDevelopmentAndResearchFeesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-75bb-b862-5b237d5c04b7" xlink:to="loc_aqst_CoDevelopmentAndResearchFeesMember_01a0eef3-16e0-7e69-bfcf-edb91153f5fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ProprietaryProductRevenueMember_01a0eef3-16e0-73c6-87a2-b628c8623370" xlink:href="aqst-20260930.xsd#aqst_ProprietaryProductRevenueMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-75bb-b862-5b237d5c04b7" xlink:to="loc_aqst_ProprietaryProductRevenueMember_01a0eef3-16e0-73c6-87a2-b628c8623370" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-16e0-7083-81df-95d74212de6e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-773a-8df2-f1725daf33d5" xlink:to="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-16e0-7083-81df-95d74212de6e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7738-84aa-60ca787c6574" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-16e0-7083-81df-95d74212de6e" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7738-84aa-60ca787c6574" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ZevraAndCommaveTherapeuticsAgreementMember_01a0eef3-16e0-7f03-b0d4-ca94a6a843bf" xlink:href="aqst-20260930.xsd#aqst_ZevraAndCommaveTherapeuticsAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7738-84aa-60ca787c6574" xlink:to="loc_aqst_ZevraAndCommaveTherapeuticsAgreementMember_01a0eef3-16e0-7f03-b0d4-ca94a6a843bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-16e0-7c74-b723-2592054db21a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-773a-8df2-f1725daf33d5" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-16e0-7c74-b723-2592054db21a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7c5d-84e9-503b7e51e438" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-16e0-7c74-b723-2592054db21a" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7c5d-84e9-503b7e51e438" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofDisaggregationofRevenueDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RevenuesandTradeReceivablesNetScheduleofDisaggregationofRevenueDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofDisaggregationofRevenueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-7185-a7ac-0939a8335f70" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-73cd-baae-10f05f6f1d21" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-7185-a7ac-0939a8335f70" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-73cd-baae-10f05f6f1d21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_01a0eef3-16e0-7f89-ae8d-d8754560d307" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_StatementGeographicalAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-73cd-baae-10f05f6f1d21" xlink:to="loc_srt_StatementGeographicalAxis_01a0eef3-16e0-7f89-ae8d-d8754560d307" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_01a0eef3-16e0-79c9-80b9-9b596459ea65" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_SegmentGeographicalDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_01a0eef3-16e0-7f89-ae8d-d8754560d307" xlink:to="loc_srt_SegmentGeographicalDomain_01a0eef3-16e0-79c9-80b9-9b596459ea65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_US_01a0eef3-16e0-72c4-a2f1-0702e8d88395" xlink:href="https://xbrl.sec.gov/country/2026/country-2026.xsd#country_US"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_01a0eef3-16e0-79c9-80b9-9b596459ea65" xlink:to="loc_country_US_01a0eef3-16e0-72c4-a2f1-0702e8d88395" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember_01a0eef3-16e0-749a-9e72-21745e268fac" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NonUsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_01a0eef3-16e0-79c9-80b9-9b596459ea65" xlink:to="loc_us-gaap_NonUsMember_01a0eef3-16e0-749a-9e72-21745e268fac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-16e0-7366-9c5f-24cec2aec8f6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-16e0-73cd-baae-10f05f6f1d21" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-16e0-7366-9c5f-24cec2aec8f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7904-b8cc-b96d4920f51e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-16e0-7366-9c5f-24cec2aec8f6" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7904-b8cc-b96d4920f51e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofTradeandOtherReceivablesNetDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RevenuesandTradeReceivablesNetScheduleofTradeandOtherReceivablesNetDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofTradeandOtherReceivablesNetDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-780b-9b09-733fef739fb5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableGross_01a0eef3-16e0-706f-abfd-0c2154ea227c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsReceivableGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-780b-9b09-733fef739fb5" xlink:to="loc_us-gaap_AccountsReceivableGross_01a0eef3-16e0-706f-abfd-0c2154ea227c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivablesGrossCurrent_01a0eef3-16e0-7f8a-8d67-d27e9155ba48" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherReceivablesGrossCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-780b-9b09-733fef739fb5" xlink:to="loc_us-gaap_OtherReceivablesGrossCurrent_01a0eef3-16e0-7f8a-8d67-d27e9155ba48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AccountsReceivableAllowanceForCreditLossPreReclassification_01a0eef3-16e0-7200-8c07-bc2e7509b590" xlink:href="aqst-20260930.xsd#aqst_AccountsReceivableAllowanceForCreditLossPreReclassification"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-780b-9b09-733fef739fb5" xlink:to="loc_aqst_AccountsReceivableAllowanceForCreditLossPreReclassification_01a0eef3-16e0-7200-8c07-bc2e7509b590" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AccountsReceivableAllowancesAndAccrualsTradeAndOtherReceivablesNet_01a0eef3-16e0-72ec-a1b6-875a0cb2db15" xlink:href="aqst-20260930.xsd#aqst_AccountsReceivableAllowancesAndAccrualsTradeAndOtherReceivablesNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-780b-9b09-733fef739fb5" xlink:to="loc_aqst_AccountsReceivableAllowancesAndAccrualsTradeAndOtherReceivablesNet_01a0eef3-16e0-72ec-a1b6-875a0cb2db15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesNetCurrent_01a0eef3-16e0-7e4b-a1d8-7c816bf80d37" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReceivablesNetCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-780b-9b09-733fef739fb5" xlink:to="loc_us-gaap_ReceivablesNetCurrent_01a0eef3-16e0-7e4b-a1d8-7c816bf80d37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofSalesrelatedAllowancesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RevenuesandTradeReceivablesNetScheduleofSalesrelatedAllowancesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RevenuesandTradeReceivablesNetScheduleofSalesrelatedAllowancesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-7971-b1e8-7773fd51ea29" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_01a0eef3-16e0-73e2-82f1-e991e272f781" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-16e0-7971-b1e8-7773fd51ea29" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_01a0eef3-16e0-73e2-82f1-e991e272f781" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-16e0-7c50-9dbe-89ae82f368c5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_01a0eef3-16e0-73e2-82f1-e991e272f781" xlink:to="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-16e0-7c50-9dbe-89ae82f368c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7723-bb4b-0d7f7c4939ea" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReceivableTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-16e0-7c50-9dbe-89ae82f368c5" xlink:to="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7723-bb4b-0d7f7c4939ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TradeAccountsReceivableSalesRelatedMember_01a0eef3-16e0-73ff-8128-68689e7fae78" xlink:href="aqst-20260930.xsd#aqst_TradeAccountsReceivableSalesRelatedMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_01a0eef3-16e0-7723-bb4b-0d7f7c4939ea" xlink:to="loc_aqst_TradeAccountsReceivableSalesRelatedMember_01a0eef3-16e0-73ff-8128-68689e7fae78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_01a0eef3-16e0-7c76-b811-aa7cf8e164af" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsNotesAndLoansReceivableLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_01a0eef3-16e0-73e2-82f1-e991e272f781" xlink:to="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_01a0eef3-16e0-7c76-b811-aa7cf8e164af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_01a0eef3-16e0-76bb-86ef-5e4f9f0fc4a1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_01a0eef3-16e0-7c76-b811-aa7cf8e164af" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_01a0eef3-16e0-76bb-86ef-5e4f9f0fc4a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-16e0-7c88-86e2-92fdebc94265" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_01a0eef3-16e0-76bb-86ef-5e4f9f0fc4a1" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-16e0-7c88-86e2-92fdebc94265" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_01a0eef3-16e0-7ec0-b619-ac99255cf6a1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_01a0eef3-16e0-76bb-86ef-5e4f9f0fc4a1" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_01a0eef3-16e0-7ec0-b619-ac99255cf6a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRecoveries_01a0eef3-16e0-79b6-addf-4e849af15588" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableRecoveries"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_01a0eef3-16e0-76bb-86ef-5e4f9f0fc4a1" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRecoveries_01a0eef3-16e0-79b6-addf-4e849af15588" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AccountsReceivableAllowanceForCreditLossReclassifications_01a0eef3-16e0-7fe6-b731-c1193095aeee" xlink:href="aqst-20260930.xsd#aqst_AccountsReceivableAllowanceForCreditLossReclassifications"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_01a0eef3-16e0-76bb-86ef-5e4f9f0fc4a1" xlink:to="loc_aqst_AccountsReceivableAllowanceForCreditLossReclassifications_01a0eef3-16e0-7fe6-b731-c1193095aeee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-16e0-722c-8d71-8e908e87baad" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_01a0eef3-16e0-76bb-86ef-5e4f9f0fc4a1" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-16e0-722c-8d71-8e908e87baad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/MaterialAgreementsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#MaterialAgreementsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/MaterialAgreementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-16e0-7de6-9b1b-985dd310c30b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-16e0-7de6-9b1b-985dd310c30b" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-7d77-89ae-bc89cb60e6d1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-7d77-89ae-bc89cb60e6d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7884-93d3-fff44fd79d3e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-7d77-89ae-bc89cb60e6d1" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7884-93d3-fff44fd79d3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OaktreeCapitalManagementLPMember_01a0eef3-16e0-77d9-a48f-380063a9f438" xlink:href="aqst-20260930.xsd#aqst_OaktreeCapitalManagementLPMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7884-93d3-fff44fd79d3e" xlink:to="loc_aqst_OaktreeCapitalManagementLPMember_01a0eef3-16e0-77d9-a48f-380063a9f438" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-76e7-9610-2fcb66283a77" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-76e7-9610-2fcb66283a77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-76d0-bb70-b7cdeb7c6bab" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-76e7-9610-2fcb66283a77" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-76d0-bb70-b7cdeb7c6bab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditMember_01a0eef3-16e0-7927-ba5f-4255c4c8e23d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-76d0-bb70-b7cdeb7c6bab" xlink:to="loc_us-gaap_LineOfCreditMember_01a0eef3-16e0-7927-ba5f-4255c4c8e23d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_01a0eef3-16e0-773a-9c02-0fb1b24177a3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SeniorNotesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-76d0-bb70-b7cdeb7c6bab" xlink:to="loc_us-gaap_SeniorNotesMember_01a0eef3-16e0-773a-9c02-0fb1b24177a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_01a0eef3-16e0-782c-86c7-23bda9d92482" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_us-gaap_CreditFacilityAxis_01a0eef3-16e0-782c-86c7-23bda9d92482" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_01a0eef3-16e0-79bc-b3ac-63ef990267cd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_01a0eef3-16e0-782c-86c7-23bda9d92482" xlink:to="loc_us-gaap_CreditFacilityDomain_01a0eef3-16e0-79bc-b3ac-63ef990267cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredDebtMember_01a0eef3-16e0-74fd-a6ea-9155bc0cf79b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-16e0-79bc-b3ac-63ef990267cd" xlink:to="loc_us-gaap_SecuredDebtMember_01a0eef3-16e0-74fd-a6ea-9155bc0cf79b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DelayedDrawTermLoanMember_01a0eef3-16e0-7624-8364-a96eb244b0e9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DelayedDrawTermLoanMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-16e0-79bc-b3ac-63ef990267cd" xlink:to="loc_us-gaap_DelayedDrawTermLoanMember_01a0eef3-16e0-7624-8364-a96eb244b0e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PurchaseAndSaleAgreementMember_01a0eef3-16e0-7b7c-a8a2-58ec7c32cbe5" xlink:href="aqst-20260930.xsd#aqst_PurchaseAndSaleAgreementMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-16e0-79bc-b3ac-63ef990267cd" xlink:to="loc_aqst_PurchaseAndSaleAgreementMember_01a0eef3-16e0-7b7c-a8a2-58ec7c32cbe5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MonetizationAgreementMember_01a0eef3-16e0-7e8a-961b-88712ab7b721" xlink:href="aqst-20260930.xsd#aqst_MonetizationAgreementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-16e0-79bc-b3ac-63ef990267cd" xlink:to="loc_aqst_MonetizationAgreementMember_01a0eef3-16e0-7e8a-961b-88712ab7b721" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseSupplyAgreementMember_01a0eef3-16e0-74ba-a296-866509ceff6f" xlink:href="aqst-20260930.xsd#aqst_LicenseSupplyAgreementMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-16e0-79bc-b3ac-63ef990267cd" xlink:to="loc_aqst_LicenseSupplyAgreementMember_01a0eef3-16e0-74ba-a296-866509ceff6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-16e0-729b-8a7a-d138f50fa5c9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-16e0-729b-8a7a-d138f50fa5c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7f7b-a5ca-2661376252ab" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-16e0-729b-8a7a-d138f50fa5c9" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7f7b-a5ca-2661376252ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TrancheAWarrantMember_01a0eef3-16e0-75aa-b3fb-f83e5f0f5bab" xlink:href="aqst-20260930.xsd#aqst_TrancheAWarrantMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7f7b-a5ca-2661376252ab" xlink:to="loc_aqst_TrancheAWarrantMember_01a0eef3-16e0-75aa-b3fb-f83e5f0f5bab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-16e0-7810-a083-84200226be2a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-16e0-7810-a083-84200226be2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-16e0-7810-a083-84200226be2a" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RTWInvestmentsLPMember_01a0eef3-16e0-76de-aafb-4a4e1d5af7d2" xlink:href="aqst-20260930.xsd#aqst_RTWInvestmentsLPMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_RTWInvestmentsLPMember_01a0eef3-16e0-76de-aafb-4a4e1d5af7d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CommercialExploitationAgreementWithIndiviorMember_01a0eef3-16e0-773f-9b1e-9e962c0b5148" xlink:href="aqst-20260930.xsd#aqst_CommercialExploitationAgreementWithIndiviorMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_CommercialExploitationAgreementWithIndiviorMember_01a0eef3-16e0-773f-9b1e-9e962c0b5148" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMilestonesMember_01a0eef3-16e0-79e5-9ce6-8b8621fd3d44" xlink:href="aqst-20260930.xsd#aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMilestonesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMilestonesMember_01a0eef3-16e0-79e5-9ce6-8b8621fd3d44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember_01a0eef3-16e0-7d4f-9ccb-58be08eb4add" xlink:href="aqst-20260930.xsd#aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember_01a0eef3-16e0-7d4f-9ccb-58be08eb4add" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncUpfrontMember_01a0eef3-16e0-7f19-81c7-fc49ba70e0fe" xlink:href="aqst-20260930.xsd#aqst_LicenseAgreementWithSunovionPharmaceuticalsIncUpfrontMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncUpfrontMember_01a0eef3-16e0-7f19-81c7-fc49ba70e0fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MarathonPangolinRoyaltyLLCMember_01a0eef3-16e0-75f9-afba-9752c673b66c" xlink:href="aqst-20260930.xsd#aqst_MarathonPangolinRoyaltyLLCMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_MarathonPangolinRoyaltyLLCMember_01a0eef3-16e0-75f9-afba-9752c673b66c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ZevraAndCommaveTherapeuticsAgreementMember_01a0eef3-16e0-7d23-a87b-85c697851b17" xlink:href="aqst-20260930.xsd#aqst_ZevraAndCommaveTherapeuticsAgreementMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_ZevraAndCommaveTherapeuticsAgreementMember_01a0eef3-16e0-7d23-a87b-85c697851b17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AtnahsPharmaUKLimitedMember_01a0eef3-16e0-7655-aa3b-c86486282a74" xlink:href="aqst-20260930.xsd#aqst_AtnahsPharmaUKLimitedMember"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_AtnahsPharmaUKLimitedMember_01a0eef3-16e0-7655-aa3b-c86486282a74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AtnahsPharmaUKLimitedAmendedAgreementMember_01a0eef3-16e0-722e-9e44-7e64133a396d" xlink:href="aqst-20260930.xsd#aqst_AtnahsPharmaUKLimitedAmendedAgreementMember"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-16e0-7a1b-a217-f1a47ddbe761" xlink:to="loc_aqst_AtnahsPharmaUKLimitedAmendedAgreementMember_01a0eef3-16e0-722e-9e44-7e64133a396d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-16e0-7b8b-bba8-96734df0dc9f" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_srt_RangeAxis_01a0eef3-16e0-7b8b-bba8-96734df0dc9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-16e0-769e-8a41-9ccb53e57cad" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-16e0-7b8b-bba8-96734df0dc9f" xlink:to="loc_srt_RangeMember_01a0eef3-16e0-769e-8a41-9ccb53e57cad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-16e0-768a-b106-99c7f9e0c1f0" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-16e0-769e-8a41-9ccb53e57cad" xlink:to="loc_srt_MinimumMember_01a0eef3-16e0-768a-b106-99c7f9e0c1f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-16e0-7d17-b577-42034d43308e" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-16e0-769e-8a41-9ccb53e57cad" xlink:to="loc_srt_MaximumMember_01a0eef3-16e0-7d17-b577-42034d43308e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7583-bf3f-214067718fe1" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7583-bf3f-214067718fe1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7850-be2e-7d44fbdd49da" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_01a0eef3-16e0-7583-bf3f-214067718fe1" xlink:to="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7850-be2e-7d44fbdd49da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAndRoyaltyRevenueMember_01a0eef3-16e0-7790-9b9b-a8a430860800" xlink:href="aqst-20260930.xsd#aqst_LicenseAndRoyaltyRevenueMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-16e0-7850-be2e-7d44fbdd49da" xlink:to="loc_aqst_LicenseAndRoyaltyRevenueMember_01a0eef3-16e0-7790-9b9b-a8a430860800" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_01a0eef3-16e0-710e-9809-174db1fe4ad4" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_srt_CounterpartyNameAxis_01a0eef3-16e0-710e-9809-174db1fe4ad4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_01a0eef3-16e0-731d-85e2-921ff474d832" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_01a0eef3-16e0-710e-9809-174db1fe4ad4" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_01a0eef3-16e0-731d-85e2-921ff474d832" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AssertioHoldingsIncMember_01a0eef3-16e0-7130-89cd-c4e511ff482d" xlink:href="aqst-20260930.xsd#aqst_AssertioHoldingsIncMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_01a0eef3-16e0-731d-85e2-921ff474d832" xlink:to="loc_aqst_AssertioHoldingsIncMember_01a0eef3-16e0-7130-89cd-c4e511ff482d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_01a0eef3-16e0-7be1-b30b-d6d6ae86fe9f" xlink:to="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_01a0eef3-16e0-7a9f-9107-02847be69d44" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_01a0eef3-16e0-7a9f-9107-02847be69d44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_01a0eef3-16e0-725b-9e1b-2a817891343a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_01a0eef3-16e0-725b-9e1b-2a817891343a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LineOfCreditFacilityAvailableBorrowingCapacityIncreaseLimit_01a0eef3-16e0-7dec-a1a8-4beacdbfbb9a" xlink:href="aqst-20260930.xsd#aqst_LineOfCreditFacilityAvailableBorrowingCapacityIncreaseLimit"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_LineOfCreditFacilityAvailableBorrowingCapacityIncreaseLimit_01a0eef3-16e0-7dec-a1a8-4beacdbfbb9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-16e0-7a21-9509-8f86fa673611" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-16e0-7a21-9509-8f86fa673611" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-16e0-772f-bc06-7dca6c4555b0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-16e0-772f-bc06-7dca6c4555b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ConsiderationReceivableFromSaleOfFutureRevenuesInterests_01a0eef3-16e0-739a-89d7-cc8d6397a90c" xlink:href="aqst-20260930.xsd#aqst_ConsiderationReceivableFromSaleOfFutureRevenuesInterests"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_ConsiderationReceivableFromSaleOfFutureRevenuesInterests_01a0eef3-16e0-739a-89d7-cc8d6397a90c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-16e0-7560-87f4-2c741c9970fd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-16e0-7560-87f4-2c741c9970fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CollaborativeArrangementRevenueSharingPercentage_01a0eef3-16e0-70f9-81a8-85bd7d00ca12" xlink:href="aqst-20260930.xsd#aqst_CollaborativeArrangementRevenueSharingPercentage"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_CollaborativeArrangementRevenueSharingPercentage_01a0eef3-16e0-70f9-81a8-85bd7d00ca12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CollaborativeArrangementEstimatedRevenueSharePaymentsUponPurchasersReceiptYearTen_01a0eef3-16e0-71ea-9e65-c6672c622b90" xlink:href="aqst-20260930.xsd#aqst_CollaborativeArrangementEstimatedRevenueSharePaymentsUponPurchasersReceiptYearTen"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_CollaborativeArrangementEstimatedRevenueSharePaymentsUponPurchasersReceiptYearTen_01a0eef3-16e0-71ea-9e65-c6672c622b90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CollaborativeArrangementEstimatedRevenueSharePaymentsUponPurchasersReceiptThereafter_01a0eef3-16e0-7183-821c-806d332a7ec2" xlink:href="aqst-20260930.xsd#aqst_CollaborativeArrangementEstimatedRevenueSharePaymentsUponPurchasersReceiptThereafter"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_CollaborativeArrangementEstimatedRevenueSharePaymentsUponPurchasersReceiptThereafter_01a0eef3-16e0-7183-821c-806d332a7ec2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CapitalizedLegalFees_01a0eef3-16e0-70ce-b01e-749c5568c49d" xlink:href="aqst-20260930.xsd#aqst_CapitalizedLegalFees"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_CapitalizedLegalFees_01a0eef3-16e0-70ce-b01e-749c5568c49d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SaleOfStockSharesCommittedAggregateAmount_01a0eef3-16e0-751e-9e3f-9dd22e7215b3" xlink:href="aqst-20260930.xsd#aqst_SaleOfStockSharesCommittedAggregateAmount"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_SaleOfStockSharesCommittedAggregateAmount_01a0eef3-16e0-751e-9e3f-9dd22e7215b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SaleOfStockShareCommitmentPeriodFollowingEffectiveDate_01a0eef3-16e0-706c-abc0-044b3eb6ae38" xlink:href="aqst-20260930.xsd#aqst_SaleOfStockShareCommitmentPeriodFollowingEffectiveDate"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_SaleOfStockShareCommitmentPeriodFollowingEffectiveDate_01a0eef3-16e0-706c-abc0-044b3eb6ae38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAgreementTerm_01a0eef3-16e0-7cfa-8a72-a54d9396cca0" xlink:href="aqst-20260930.xsd#aqst_LicenseAgreementTerm"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_LicenseAgreementTerm_01a0eef3-16e0-7cfa-8a72-a54d9396cca0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AutomaticRenewalPeriodOfAgreement_01a0eef3-16e0-7888-a53b-f267820b8fd9" xlink:href="aqst-20260930.xsd#aqst_AutomaticRenewalPeriodOfAgreement"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_AutomaticRenewalPeriodOfAgreement_01a0eef3-16e0-7888-a53b-f267820b8fd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NoticeOfRenewalPeriodPriorToExpiration_01a197d4-fd29-78ec-819f-5699ce24b814" xlink:href="aqst-20260930.xsd#aqst_NoticeOfRenewalPeriodPriorToExpiration"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_NoticeOfRenewalPeriodPriorToExpiration_01a197d4-fd29-78ec-819f-5699ce24b814" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AdditionalRenewalPeriodOfAgreement_01a197d3-a87f-7453-b6b7-02c22a1b384a" xlink:href="aqst-20260930.xsd#aqst_AdditionalRenewalPeriodOfAgreement"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_AdditionalRenewalPeriodOfAgreement_01a197d3-a87f-7453-b6b7-02c22a1b384a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7e5d-a921-15bda8211720" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-16e0-7e5d-a921-15bda8211720" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_01a0eef3-16e0-725b-a33a-ff1a6c4645ea" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Revenues"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_Revenues_01a0eef3-16e0-725b-a33a-ff1a6c4645ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ProceedsFromSaleOfFutureRevenuesNet_01a0eef3-16e0-779e-bbbd-c111556f73a6" xlink:href="aqst-20260930.xsd#aqst_ProceedsFromSaleOfFutureRevenuesNet"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_ProceedsFromSaleOfFutureRevenuesNet_01a0eef3-16e0-779e-bbbd-c111556f73a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AdditionalProceedsFromSaleOfFutureRevenuesNet_01a0eef3-16e0-78b3-bd14-3a071a0d0ecc" xlink:href="aqst-20260930.xsd#aqst_AdditionalProceedsFromSaleOfFutureRevenuesNet"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_AdditionalProceedsFromSaleOfFutureRevenuesNet_01a0eef3-16e0-78b3-bd14-3a071a0d0ecc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ContingentMonetizationAgreementMilestonePayment_01a0eef3-16e0-7fef-8ec6-a6a4a61d4279" xlink:href="aqst-20260930.xsd#aqst_ContingentMonetizationAgreementMilestonePayment"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_aqst_ContingentMonetizationAgreementMilestonePayment_01a0eef3-16e0-7fef-8ec6-a6a4a61d4279" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromCollaborators_01a0eef3-16e0-7d18-be88-e12feaf20ebb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromCollaborators"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_01a0eef3-16e0-76ad-8c4d-893f2e25ed2a" xlink:to="loc_us-gaap_ProceedsFromCollaborators_01a0eef3-16e0-7d18-be88-e12feaf20ebb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/FinancialInstrumentsFairValueMeasurementsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#FinancialInstrumentsFairValueMeasurementsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/FinancialInstrumentsFairValueMeasurementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_01a0eef3-16e0-70a6-9d6f-5dbb7e160d74" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_01a0eef3-16e0-70a6-9d6f-5dbb7e160d74" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-7406-8a0c-78fd4f519c82" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-7406-8a0c-78fd4f519c82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-7fa2-a27a-0a96d6eea168" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_01a0eef3-16e0-7406-8a0c-78fd4f519c82" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-7fa2-a27a-0a96d6eea168" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SecuritiesPurchaseAgreementMember_01a0eef3-16e0-7584-b76c-3fdc6aaff781" xlink:href="aqst-20260930.xsd#aqst_SecuritiesPurchaseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_01a0eef3-16e0-7fa2-a27a-0a96d6eea168" xlink:to="loc_aqst_SecuritiesPurchaseAgreementMember_01a0eef3-16e0-7584-b76c-3fdc6aaff781" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-16e0-7b1a-9d72-58bec89b49fa" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-16e0-7b1a-9d72-58bec89b49fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7938-bf8f-b68ef16ce72a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-16e0-7b1a-9d72-58bec89b49fa" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7938-bf8f-b68ef16ce72a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ExistingWarrantsMember_01a0eef3-16e0-7d90-b1a3-8b7384fff908" xlink:href="aqst-20260930.xsd#aqst_ExistingWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7938-bf8f-b68ef16ce72a" xlink:to="loc_aqst_ExistingWarrantsMember_01a0eef3-16e0-7d90-b1a3-8b7384fff908" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NewWarrantsMember_01a0eef3-16e0-76ef-83c4-963aaeb391c7" xlink:href="aqst-20260930.xsd#aqst_NewWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7938-bf8f-b68ef16ce72a" xlink:to="loc_aqst_NewWarrantsMember_01a0eef3-16e0-76ef-83c4-963aaeb391c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CommonStockWarrantsMember_01a0eef3-16e0-7a2e-81d1-473fda0bd656" xlink:href="aqst-20260930.xsd#aqst_CommonStockWarrantsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7938-bf8f-b68ef16ce72a" xlink:to="loc_aqst_CommonStockWarrantsMember_01a0eef3-16e0-7a2e-81d1-473fda0bd656" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TrancheAWarrantMember_01a11aaf-f74c-7c10-9981-425d69febe52" xlink:href="aqst-20260930.xsd#aqst_TrancheAWarrantMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-16e0-7938-bf8f-b68ef16ce72a" xlink:to="loc_aqst_TrancheAWarrantMember_01a11aaf-f74c-7c10-9981-425d69febe52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-7166-a35e-7366e63d830f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:to="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-7166-a35e-7366e63d830f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7aeb-ab0b-0925666c857a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_01a0eef3-16e0-7166-a35e-7366e63d830f" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7aeb-ab0b-0925666c857a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-16e0-7b4f-9da7-7b90d739b457" xlink:href="aqst-20260930.xsd#aqst_SeniorSecuredNotes13.5DueNovember12028Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7aeb-ab0b-0925666c857a" xlink:to="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-16e0-7b4f-9da7-7b90d739b457" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OaktreeCapitalManagementLPMember_01a11aaf-f74c-78e5-8367-fbe75140e7a1" xlink:href="aqst-20260930.xsd#aqst_OaktreeCapitalManagementLPMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-16e0-7aeb-ab0b-0925666c857a" xlink:to="loc_aqst_OaktreeCapitalManagementLPMember_01a11aaf-f74c-78e5-8367-fbe75140e7a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-75eb-a722-9ed60e585309" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-75eb-a722-9ed60e585309" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-7c03-89e7-f677fa2b34d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-16e0-75eb-a722-9ed60e585309" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-7c03-89e7-f677fa2b34d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_01a0eef3-16e0-7047-8c69-189259ee525a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-7c03-89e7-f677fa2b34d9" xlink:to="loc_us-gaap_SeniorNotesMember_01a0eef3-16e0-7047-8c69-189259ee525a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditMember_01a11aaf-f74c-78aa-918d-4c4566a5182a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-16e0-7c03-89e7-f677fa2b34d9" xlink:to="loc_us-gaap_LineOfCreditMember_01a11aaf-f74c-78aa-918d-4c4566a5182a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-16e0-7820-b4c5-13c75e537ad0" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:to="loc_srt_RangeAxis_01a0eef3-16e0-7820-b4c5-13c75e537ad0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-16e0-7618-ba98-0ba987974ab7" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-16e0-7820-b4c5-13c75e537ad0" xlink:to="loc_srt_RangeMember_01a0eef3-16e0-7618-ba98-0ba987974ab7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-16e0-7117-90ea-96e66dd3ca69" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-16e0-7618-ba98-0ba987974ab7" xlink:to="loc_srt_MinimumMember_01a0eef3-16e0-7117-90ea-96e66dd3ca69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-16e0-7b0e-ad3d-df3deeaee364" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-16e0-7618-ba98-0ba987974ab7" xlink:to="loc_srt_MaximumMember_01a0eef3-16e0-7b0e-ad3d-df3deeaee364" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-16e0-71d7-b02b-efe916c0342f" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SharesOfCommonStockEntitledToPurchasersByPreFundedWarrants_01a0eef3-16e0-7ef6-b11f-0517b55b7411" xlink:href="aqst-20260930.xsd#aqst_SharesOfCommonStockEntitledToPurchasersByPreFundedWarrants"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_aqst_SharesOfCommonStockEntitledToPurchasersByPreFundedWarrants_01a0eef3-16e0-7ef6-b11f-0517b55b7411" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SharesOfCommonStockToBePurchasedByCommonStockWarrants_01a0eef3-16e0-70fb-bd5e-5ce0d1670654" xlink:href="aqst-20260930.xsd#aqst_SharesOfCommonStockToBePurchasedByCommonStockWarrants"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_aqst_SharesOfCommonStockToBePurchasedByCommonStockWarrants_01a0eef3-16e0-70fb-bd5e-5ce0d1670654" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_01a0eef3-16e0-7d2f-a7d3-98f2b396375b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_01a0eef3-16e0-7d2f-a7d3-98f2b396375b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-16e0-708f-842c-89c26c3e996c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-16e0-708f-842c-89c26c3e996c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-177f-7ec9-9407-9d8a3cf695d8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-177f-7ec9-9407-9d8a3cf695d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-177f-7ae7-bdd9-2b2772281ee6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-177f-7ae7-bdd9-2b2772281ee6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationPercentOfNetSales_01a0eef3-177f-7cbe-b6c4-73d34f3f7183" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationPercentOfNetSales"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_aqst_RoyaltyObligationPercentOfNetSales_01a0eef3-177f-7cbe-b6c4-73d34f3f7183" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationTerm_01a0eef3-177f-7e7b-af67-34a7b58f7757" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationTerm"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_aqst_RoyaltyObligationTerm_01a0eef3-177f-7e7b-af67-34a7b58f7757" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_01a0eef3-177f-7ce1-b3cb-30fd741eb89e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-16e0-7848-aaa1-afe78ae86367" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_01a0eef3-177f-7ce1-b3cb-30fd741eb89e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/InventoriesNetDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#InventoriesNetDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/InventoriesNetDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7eb8-b084-14bb351491bd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterials_01a0eef3-177f-7c64-a409-8e7df7879156" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryRawMaterials"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7eb8-b084-14bb351491bd" xlink:to="loc_us-gaap_InventoryRawMaterials_01a0eef3-177f-7c64-a409-8e7df7879156" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_InventoryPackingMaterialGross_01a0eef3-177f-7e20-b6e7-9098cca6cc6b" xlink:href="aqst-20260930.xsd#aqst_InventoryPackingMaterialGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7eb8-b084-14bb351491bd" xlink:to="loc_aqst_InventoryPackingMaterialGross_01a0eef3-177f-7e20-b6e7-9098cca6cc6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoods_01a0eef3-177f-74fe-908e-4ffaba98cc05" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryFinishedGoods"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7eb8-b084-14bb351491bd" xlink:to="loc_us-gaap_InventoryFinishedGoods_01a0eef3-177f-74fe-908e-4ffaba98cc05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_01a0eef3-177f-7613-a33f-1b6b993d8989" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_01a0eef3-177f-7eb8-b084-14bb351491bd" xlink:to="loc_us-gaap_InventoryNet_01a0eef3-177f-7613-a33f-1b6b993d8989" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/PropertyandEquipmentNetScheduleofPropertyandEquipmentDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#PropertyandEquipmentNetScheduleofPropertyandEquipmentDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/PropertyandEquipmentNetScheduleofPropertyandEquipmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-7f7a-b3a3-fedbf2a3eb8d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_01a0eef3-177f-7f8b-9fb7-98788e8fca5c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-7f7a-b3a3-fedbf2a3eb8d" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_01a0eef3-177f-7f8b-9fb7-98788e8fca5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_01a0eef3-177f-7ab2-a573-e321d7b30c84" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_01a0eef3-177f-7f8b-9fb7-98788e8fca5c" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_01a0eef3-177f-7ab2-a573-e321d7b30c84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_01a0eef3-177f-7ed7-bb5b-d1bc9509563d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_01a0eef3-177f-7ab2-a573-e321d7b30c84" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_01a0eef3-177f-7ed7-bb5b-d1bc9509563d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MachineryAndEquipmentMember_01a0eef3-177f-79a6-b605-e4f42773ef39" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MachineryAndEquipmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_01a0eef3-177f-7ed7-bb5b-d1bc9509563d" xlink:to="loc_us-gaap_MachineryAndEquipmentMember_01a0eef3-177f-79a6-b605-e4f42773ef39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_01a0eef3-177f-7039-a5c3-9794d597bc97" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FurnitureAndFixturesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_01a0eef3-177f-7ed7-bb5b-d1bc9509563d" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_01a0eef3-177f-7039-a5c3-9794d597bc97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseholdImprovementsMember_01a0eef3-177f-7a8f-b4c6-98c07fecdcb6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LeaseholdImprovementsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_01a0eef3-177f-7ed7-bb5b-d1bc9509563d" xlink:to="loc_us-gaap_LeaseholdImprovementsMember_01a0eef3-177f-7a8f-b4c6-98c07fecdcb6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ComputerNetworkEquipmentAndSoftwareMember_01a0eef3-177f-7b07-aae6-486862e61e08" xlink:href="aqst-20260930.xsd#aqst_ComputerNetworkEquipmentAndSoftwareMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_01a0eef3-177f-7ed7-bb5b-d1bc9509563d" xlink:to="loc_aqst_ComputerNetworkEquipmentAndSoftwareMember_01a0eef3-177f-7b07-aae6-486862e61e08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConstructionInProgressMember_01a0eef3-177f-7348-afa1-19b52360aad7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ConstructionInProgressMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_01a0eef3-177f-7ed7-bb5b-d1bc9509563d" xlink:to="loc_us-gaap_ConstructionInProgressMember_01a0eef3-177f-7348-afa1-19b52360aad7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-177f-7a63-8e83-0a2c8c23910c" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_01a0eef3-177f-7f8b-9fb7-98788e8fca5c" xlink:to="loc_srt_RangeAxis_01a0eef3-177f-7a63-8e83-0a2c8c23910c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-177f-711c-bbd7-54702f40b949" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-177f-7a63-8e83-0a2c8c23910c" xlink:to="loc_srt_RangeMember_01a0eef3-177f-711c-bbd7-54702f40b949" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-177f-7787-b196-7172f3640a65" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-711c-bbd7-54702f40b949" xlink:to="loc_srt_MinimumMember_01a0eef3-177f-7787-b196-7172f3640a65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-177f-7f01-94fc-8f54176710f0" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-711c-bbd7-54702f40b949" xlink:to="loc_srt_MaximumMember_01a0eef3-177f-7f01-94fc-8f54176710f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_01a1860c-be0b-7b46-aa5b-c51893d81a7c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisposalGroupClassificationAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_01a0eef3-177f-7f8b-9fb7-98788e8fca5c" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_01a1860c-be0b-7b46-aa5b-c51893d81a7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_01a1860c-be0b-7b6a-a4a3-9d39ff54e050" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisposalGroupClassificationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_01a1860c-be0b-7b46-aa5b-c51893d81a7c" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_01a1860c-be0b-7b6a-a4a3-9d39ff54e050" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupNotDiscontinuedOperationsMember_01a1860c-e7da-72fd-a552-4ab057a92bb4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisposalGroupNotDiscontinuedOperationsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_01a1860c-be0b-7b6a-a4a3-9d39ff54e050" xlink:to="loc_us-gaap_DisposalGroupNotDiscontinuedOperationsMember_01a1860c-e7da-72fd-a552-4ab057a92bb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_01a0eef3-177f-700b-9bb0-60070bd0ac95" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_01a0eef3-177f-7f8b-9fb7-98788e8fca5c" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_01a0eef3-177f-700b-9bb0-60070bd0ac95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_01a0eef3-177f-77c0-b99e-c0a63ebf3c26" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_01a0eef3-177f-700b-9bb0-60070bd0ac95" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_01a0eef3-177f-77c0-b99e-c0a63ebf3c26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_01a0eef3-177f-73f7-a9d2-faa5d55020fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_01a0eef3-177f-700b-9bb0-60070bd0ac95" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_01a0eef3-177f-73f7-a9d2-faa5d55020fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_01a0eef3-177f-715e-a67a-2ccc48f4f82c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_01a0eef3-177f-700b-9bb0-60070bd0ac95" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_01a0eef3-177f-715e-a67a-2ccc48f4f82c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_01a0eef3-177f-7e69-b63f-981e1a9df878" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_01a0eef3-177f-700b-9bb0-60070bd0ac95" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_01a0eef3-177f-7e69-b63f-981e1a9df878" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipment_01a15837-92b8-7e73-a9cb-78f8e8ee0c8b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipment"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_01a0eef3-177f-700b-9bb0-60070bd0ac95" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipment_01a15837-92b8-7e73-a9cb-78f8e8ee0c8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/PropertyandEquipmentNetNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#PropertyandEquipmentNetNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/PropertyandEquipmentNetNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-75e4-9fa4-07653a56170c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_01a0eef3-177f-76c4-8106-fb91ee5999a9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_01a0eef3-177f-75e4-9fa4-07653a56170c" xlink:to="loc_us-gaap_Depreciation_01a0eef3-177f-76c4-8106-fb91ee5999a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RightofUseAssetsandLeaseObligationsNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RightofUseAssetsandLeaseObligationsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RightofUseAssetsandLeaseObligationsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_01a0eef3-177f-708b-9e49-f724ebcdeac5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_01a0eef3-177f-70b2-a729-1dba9d87f42e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeLeaseDescriptionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-708b-9e49-f724ebcdeac5" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_01a0eef3-177f-70b2-a729-1dba9d87f42e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-177f-7849-97a5-f3f91ab4619c" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_01a0eef3-177f-70b2-a729-1dba9d87f42e" xlink:to="loc_srt_RangeAxis_01a0eef3-177f-7849-97a5-f3f91ab4619c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-177f-72bd-b5e7-670ae76e8a9f" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-177f-7849-97a5-f3f91ab4619c" xlink:to="loc_srt_RangeMember_01a0eef3-177f-72bd-b5e7-670ae76e8a9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-177f-7603-880a-1c9d6e19ced1" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-72bd-b5e7-670ae76e8a9f" xlink:to="loc_srt_MinimumMember_01a0eef3-177f-7603-880a-1c9d6e19ced1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-177f-7515-a9cb-d751f43b697f" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-72bd-b5e7-670ae76e8a9f" xlink:to="loc_srt_MaximumMember_01a0eef3-177f-7515-a9cb-d751f43b697f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseContractualTermAxis_01a0eef3-177f-75ee-995c-e11ca98a25da" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LeaseContractualTermAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_01a0eef3-177f-70b2-a729-1dba9d87f42e" xlink:to="loc_us-gaap_LeaseContractualTermAxis_01a0eef3-177f-75ee-995c-e11ca98a25da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseContractualTermDomain_01a0eef3-177f-7f87-a68a-388fd729e87e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LeaseContractualTermDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseContractualTermAxis_01a0eef3-177f-75ee-995c-e11ca98a25da" xlink:to="loc_us-gaap_LeaseContractualTermDomain_01a0eef3-177f-7f87-a68a-388fd729e87e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CorporateHeadquarterLeaseMember_01a0eef3-177f-7c5d-9514-58cef8f50d58" xlink:href="aqst-20260930.xsd#aqst_CorporateHeadquarterLeaseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseContractualTermDomain_01a0eef3-177f-7f87-a68a-388fd729e87e" xlink:to="loc_aqst_CorporateHeadquarterLeaseMember_01a0eef3-177f-7c5d-9514-58cef8f50d58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ResearchAndLaboratorySpaceLeaseMember_01a19844-50ae-72f1-b154-3d2b64042571" xlink:href="aqst-20260930.xsd#aqst_ResearchAndLaboratorySpaceLeaseMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseContractualTermDomain_01a0eef3-177f-7f87-a68a-388fd729e87e" xlink:to="loc_aqst_ResearchAndLaboratorySpaceLeaseMember_01a19844-50ae-72f1-b154-3d2b64042571" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeLeaseDescriptionLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_01a0eef3-177f-70b2-a729-1dba9d87f42e" xlink:to="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseTermOfContract_01a0eef3-177f-7d33-97db-3dd1d8740070" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseTermOfContract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_LesseeOperatingLeaseTermOfContract_01a0eef3-177f-7d33-97db-3dd1d8740070" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LesseeOperatingLeaseInitialRentAbatementPeriod_01a0eef3-177f-71b2-b10d-4aed2a44e716" xlink:href="aqst-20260930.xsd#aqst_LesseeOperatingLeaseInitialRentAbatementPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_aqst_LesseeOperatingLeaseInitialRentAbatementPeriod_01a0eef3-177f-71b2-b10d-4aed2a44e716" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LesseeOperatingLeaseNumberOfRenewalOptions_01a0eef3-177f-7fb2-8a3c-2736345a043f" xlink:href="aqst-20260930.xsd#aqst_LesseeOperatingLeaseNumberOfRenewalOptions"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_aqst_LesseeOperatingLeaseNumberOfRenewalOptions_01a0eef3-177f-7fb2-8a3c-2736345a043f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_01a0eef3-177f-7165-9a18-3f0944f20db1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseRenewalTerm"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_01a0eef3-177f-7165-9a18-3f0944f20db1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_01a0eef3-177f-755d-ae4d-f0064ef0ce41" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_01a0eef3-177f-755d-ae4d-f0064ef0ce41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_01a0eef3-177f-72c2-bd49-ac879aa3d5a4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_OperatingLeaseLiability_01a0eef3-177f-72c2-bd49-ac879aa3d5a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OperatingLeaseRightOfUseAssetWriteoff_01a1980d-71f3-77a6-82c4-0274461ad354" xlink:href="aqst-20260930.xsd#aqst_OperatingLeaseRightOfUseAssetWriteoff"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_aqst_OperatingLeaseRightOfUseAssetWriteoff_01a1980d-71f3-77a6-82c4-0274461ad354" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NumberOfLeaseExtensions_01a19844-d7f1-75c3-a31e-7027d5e31e55" xlink:href="aqst-20260930.xsd#aqst_NumberOfLeaseExtensions"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_aqst_NumberOfLeaseExtensions_01a19844-d7f1-75c3-a31e-7027d5e31e55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LesseeOperatingLeaseExtensionTerm_01a19846-0aa6-743f-a2c2-e612ba19d29f" xlink:href="aqst-20260930.xsd#aqst_LesseeOperatingLeaseExtensionTerm"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_aqst_LesseeOperatingLeaseExtensionTerm_01a19846-0aa6-743f-a2c2-e612ba19d29f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OperatingLeaseLiabilityWriteoff_01a1980c-778c-7916-8e28-5fd3860be704" xlink:href="aqst-20260930.xsd#aqst_OperatingLeaseLiabilityWriteoff"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_aqst_OperatingLeaseLiabilityWriteoff_01a1980c-778c-7916-8e28-5fd3860be704" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NumberOfOperatingLeases_01a0eef3-177f-70d7-8b00-691fd456ea92" xlink:href="aqst-20260930.xsd#aqst_NumberOfOperatingLeases"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_aqst_NumberOfOperatingLeases_01a0eef3-177f-70d7-8b00-691fd456ea92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRemainingLeaseTerm_01a0eef3-177f-7d79-9207-d7b1b1d7f3d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseRemainingLeaseTerm"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_LesseeOperatingLeaseRemainingLeaseTerm_01a0eef3-177f-7d79-9207-d7b1b1d7f3d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseDiscountRate_01a0eef3-177f-7147-a912-3e224fa1fcdd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseDiscountRate"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_LesseeOperatingLeaseDiscountRate_01a0eef3-177f-7147-a912-3e224fa1fcdd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_01a0eef3-177f-795a-b831-08de8c5ff6bd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseCost"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_OperatingLeaseCost_01a0eef3-177f-795a-b831-08de8c5ff6bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableLeaseCost_01a0eef3-177f-7b62-b803-9a33caf16ea0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_VariableLeaseCost"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_01a0eef3-177f-72a2-9ab9-8158d66d1ea7" xlink:to="loc_us-gaap_VariableLeaseCost_01a0eef3-177f-7b62-b803-9a33caf16ea0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/RightofUseAssetsandLeaseObligationsScheduleofOperatingLeaseLiabilitiesMaturitiesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#RightofUseAssetsandLeaseObligationsScheduleofOperatingLeaseLiabilitiesMaturitiesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/RightofUseAssetsandLeaseObligationsScheduleofOperatingLeaseLiabilitiesMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_01a0eef3-177f-7cc0-b7b5-198a37301252" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_01a0eef3-177f-7cc0-b7b5-198a37301252" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_01a0eef3-177f-7120-a72f-432f39012cec" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_01a0eef3-177f-7120-a72f-432f39012cec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_01a0eef3-177f-7f69-b6b5-107930ae6e23" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_01a0eef3-177f-7f69-b6b5-107930ae6e23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_01a0eef3-177f-770f-9709-f0c26fbd87b2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_01a0eef3-177f-770f-9709-f0c26fbd87b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LesseeOperatingLeaseLiabilityToBePaidYearFourAndThereafter_01a0eef3-177f-7199-9572-ca8ecdf58d95" xlink:href="aqst-20260930.xsd#aqst_LesseeOperatingLeaseLiabilityToBePaidYearFourAndThereafter"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_aqst_LesseeOperatingLeaseLiabilityToBePaidYearFourAndThereafter_01a0eef3-177f-7199-9572-ca8ecdf58d95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_01a0eef3-177f-73d6-a94b-2a51043e26ac" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_01a0eef3-177f-73d6-a94b-2a51043e26ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_01a0eef3-177f-7122-a508-34f023030aa2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_01a0eef3-177f-7122-a508-34f023030aa2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_01a0eef3-177f-7ef7-b3ad-71628edb5dd7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_01a0eef3-177f-7257-a930-fa1be28a7075" xlink:to="loc_us-gaap_OperatingLeaseLiability_01a0eef3-177f-7ef7-b3ad-71628edb5dd7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNoncurrentAssetsScheduleofOtherNonCurrentAssetsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNoncurrentAssetsScheduleofOtherNonCurrentAssetsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNoncurrentAssetsScheduleofOtherNonCurrentAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7191-b186-61dac24548d6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CumulativeRoyaltyReceivable_01a0eef3-177f-72f4-a5b5-7c4976a46079" xlink:href="aqst-20260930.xsd#aqst_CumulativeRoyaltyReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7191-b186-61dac24548d6" xlink:to="loc_aqst_CumulativeRoyaltyReceivable_01a0eef3-177f-72f4-a5b5-7c4976a46079" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsMiscellaneousNoncurrent_01a0eef3-177f-743c-b508-0abe53bd536c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAssetsMiscellaneousNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7191-b186-61dac24548d6" xlink:to="loc_us-gaap_OtherAssetsMiscellaneousNoncurrent_01a0eef3-177f-743c-b508-0abe53bd536c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_01a0eef3-177f-7648-b6ce-eed5b8452db1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-7191-b186-61dac24548d6" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_01a0eef3-177f-7648-b6ce-eed5b8452db1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNoncurrentAssetsNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNoncurrentAssetsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNoncurrentAssetsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-77bb-9386-ec04f7352d26" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_01a0eef3-177f-779a-bed4-caefbd480f7a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_01a0eef3-177f-77bb-9386-ec04f7352d26" xlink:to="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_01a0eef3-177f-779a-bed4-caefbd480f7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_01a0eef3-177f-709a-bfb1-824de630189b" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_01a0eef3-177f-779a-bed4-caefbd480f7a" xlink:to="loc_srt_ProductOrServiceAxis_01a0eef3-177f-709a-bfb1-824de630189b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-7215-80b6-5de28a299104" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_01a0eef3-177f-709a-bfb1-824de630189b" xlink:to="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-7215-80b6-5de28a299104" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RoyaltyMember_01a0eef3-177f-7d41-a6af-3667ee69476e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RoyaltyMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-7215-80b6-5de28a299104" xlink:to="loc_us-gaap_RoyaltyMember_01a0eef3-177f-7d41-a6af-3667ee69476e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-177f-7977-a618-8f46618dffd9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_01a0eef3-177f-779a-bed4-caefbd480f7a" xlink:to="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-177f-7977-a618-8f46618dffd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-177f-7b2e-aabb-94bdf9514085" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-177f-7977-a618-8f46618dffd9" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-177f-7b2e-aabb-94bdf9514085" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember_01a0eef3-177f-7595-bb32-4f1be5a9f381" xlink:href="aqst-20260930.xsd#aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-177f-7b2e-aabb-94bdf9514085" xlink:to="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember_01a0eef3-177f-7595-bb32-4f1be5a9f381" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_01a0eef3-177f-71f4-8059-906178c8073a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAcquiredFiniteLivedIntangibleAssetByMajorClassTable_01a0eef3-177f-779a-bed4-caefbd480f7a" xlink:to="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_01a0eef3-177f-71f4-8059-906178c8073a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-177f-74d3-89fd-fb20589ef78c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_01a0eef3-177f-71f4-8059-906178c8073a" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-177f-74d3-89fd-fb20589ef78c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NumberOfGuaranteedRoyaltyPayments_01a0eef3-177f-7747-9629-64eef9ebafb0" xlink:href="aqst-20260930.xsd#aqst_NumberOfGuaranteedRoyaltyPayments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_01a0eef3-177f-71f4-8059-906178c8073a" xlink:to="loc_aqst_NumberOfGuaranteedRoyaltyPayments_01a0eef3-177f-7747-9629-64eef9ebafb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MinimumAnnualRoyaltyReceivable_01a0eef3-177f-73b1-8a32-42283b1ba9fc" xlink:href="aqst-20260930.xsd#aqst_MinimumAnnualRoyaltyReceivable"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_01a0eef3-177f-71f4-8059-906178c8073a" xlink:to="loc_aqst_MinimumAnnualRoyaltyReceivable_01a0eef3-177f-73b1-8a32-42283b1ba9fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NumberOfAnnualRoyaltyPaymentsReceivable_01a0eef3-177f-75e2-962f-dcfc53111835" xlink:href="aqst-20260930.xsd#aqst_NumberOfAnnualRoyaltyPaymentsReceivable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_01a0eef3-177f-71f4-8059-906178c8073a" xlink:to="loc_aqst_NumberOfAnnualRoyaltyPaymentsReceivable_01a0eef3-177f-75e2-962f-dcfc53111835" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/AccruedExpensesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#AccruedExpensesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/AccruedExpensesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_01a0eef3-177f-7197-8140-f2f61295fc24" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PayablesAndAccrualsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShortTermDebtTable_01a0eef3-177f-7e01-b32c-b67a34960070" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShortTermDebtTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_01a0eef3-177f-7197-8140-f2f61295fc24" xlink:to="loc_us-gaap_ScheduleOfShortTermDebtTable_01a0eef3-177f-7e01-b32c-b67a34960070" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-177f-7221-8805-0fca18e41878" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShortTermDebtTable_01a0eef3-177f-7e01-b32c-b67a34960070" xlink:to="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-177f-7221-8805-0fca18e41878" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivableTypeDomain_01a0eef3-177f-7df2-9192-3b2fcd85a57a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReceivableTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_01a0eef3-177f-7221-8805-0fca18e41878" xlink:to="loc_us-gaap_ReceivableTypeDomain_01a0eef3-177f-7df2-9192-3b2fcd85a57a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OtherReceivablesAndAccruedExpensesMember_01a0eef3-177f-7f2a-a2f1-e8a702222b7a" xlink:href="aqst-20260930.xsd#aqst_OtherReceivablesAndAccruedExpensesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_01a0eef3-177f-7df2-9192-3b2fcd85a57a" xlink:to="loc_aqst_OtherReceivablesAndAccruedExpensesMember_01a0eef3-177f-7f2a-a2f1-e8a702222b7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShortTermDebtLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShortTermDebtTable_01a0eef3-177f-7e01-b32c-b67a34960070" xlink:to="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_01a0eef3-177f-7759-b69e-9aa03cf28979" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_01a0eef3-177f-7759-b69e-9aa03cf28979" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxesPayableCurrent_01a0eef3-177f-7c01-82fc-cd5050639d6c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TaxesPayableCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:to="loc_us-gaap_TaxesPayableCurrent_01a0eef3-177f-7c01-82fc-cd5050639d6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-177f-7072-ab26-fb5cc93e5e36" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_01a0eef3-177f-7072-ab26-fb5cc93e5e36" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPayableCurrent_01a0eef3-177f-7bb5-88ae-935ff9c119cd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestPayableCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:to="loc_us-gaap_InterestPayableCurrent_01a0eef3-177f-7bb5-88ae-935ff9c119cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_01a0eef3-177f-73bf-a716-f5e3923b5709" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_01a0eef3-177f-73bf-a716-f5e3923b5709" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_01a0eef3-177f-7f51-88c2-c8ee3070f2cd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShortTermDebtLineItems_01a0eef3-177f-7311-8206-9035f21f69a7" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_01a0eef3-177f-7f51-88c2-c8ee3070f2cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/LongTermDebtNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#LongTermDebtNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/LongTermDebtNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-7fc8-b15a-5a7319880e35" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-7fc8-b15a-5a7319880e35" xlink:to="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7d13-a1d5-2be0b75fb2e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7d13-a1d5-2be0b75fb2e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-79cf-885a-21ceedd765d3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7d13-a1d5-2be0b75fb2e2" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-79cf-885a-21ceedd765d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-177f-7daf-912c-9a5cd91dc203" xlink:href="aqst-20260930.xsd#aqst_SeniorSecuredNotes13.5DueNovember12028Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-79cf-885a-21ceedd765d3" xlink:to="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-177f-7daf-912c-9a5cd91dc203" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TwelvePointFiveSeniorSecuredNotesDueJune302025Member_01a0eef3-177f-71d5-8959-b87ff7834d42" xlink:href="aqst-20260930.xsd#aqst_TwelvePointFiveSeniorSecuredNotesDueJune302025Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-79cf-885a-21ceedd765d3" xlink:to="loc_aqst_TwelvePointFiveSeniorSecuredNotesDueJune302025Member_01a0eef3-177f-71d5-8959-b87ff7834d42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationsMember_01a0eef3-177f-720e-8318-a21b28b3ac6e" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-79cf-885a-21ceedd765d3" xlink:to="loc_aqst_RoyaltyObligationsMember_01a0eef3-177f-720e-8318-a21b28b3ac6e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyRightAgreementsMember_01a0eef3-177f-7935-b395-b41925c7fb54" xlink:href="aqst-20260930.xsd#aqst_RoyaltyRightAgreementsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-79cf-885a-21ceedd765d3" xlink:to="loc_aqst_RoyaltyRightAgreementsMember_01a0eef3-177f-7935-b395-b41925c7fb54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OaktreeCapitalManagementLPMember_01a0eef3-177f-73f5-8165-aea774ce54a8" xlink:href="aqst-20260930.xsd#aqst_OaktreeCapitalManagementLPMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-79cf-885a-21ceedd765d3" xlink:to="loc_aqst_OaktreeCapitalManagementLPMember_01a0eef3-177f-73f5-8165-aea774ce54a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7bb3-bac0-50aa82288707" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7bb3-bac0-50aa82288707" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e57-b865-60827c1e26e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7bb3-bac0-50aa82288707" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e57-b865-60827c1e26e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_01a0eef3-177f-71fd-8cad-d9345e944f20" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e57-b865-60827c1e26e2" xlink:to="loc_us-gaap_SeniorNotesMember_01a0eef3-177f-71fd-8cad-d9345e944f20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember_01a0eef3-177f-7d67-b813-5197d2eb9e1b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_UnsecuredDebtMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e57-b865-60827c1e26e2" xlink:to="loc_us-gaap_UnsecuredDebtMember_01a0eef3-177f-7d67-b813-5197d2eb9e1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditMember_01a0eef3-177f-7058-88b9-e2cc9f07c359" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e57-b865-60827c1e26e2" xlink:to="loc_us-gaap_LineOfCreditMember_01a0eef3-177f-7058-88b9-e2cc9f07c359" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-177f-778a-b969-d339114524cd" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_srt_RangeAxis_01a0eef3-177f-778a-b969-d339114524cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-177f-7152-854f-5d9b1b499a0b" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-177f-778a-b969-d339114524cd" xlink:to="loc_srt_RangeMember_01a0eef3-177f-7152-854f-5d9b1b499a0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-177f-7062-b48e-24f2b95098b8" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-7152-854f-5d9b1b499a0b" xlink:to="loc_srt_MinimumMember_01a0eef3-177f-7062-b48e-24f2b95098b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-177f-75b2-be9f-a55444742cc3" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-7152-854f-5d9b1b499a0b" xlink:to="loc_srt_MaximumMember_01a0eef3-177f-75b2-be9f-a55444742cc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_01a0eef3-177f-7dca-8463-01a184c7d625" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_us-gaap_CreditFacilityAxis_01a0eef3-177f-7dca-8463-01a184c7d625" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_01a0eef3-177f-74e8-bcba-37a17cc808a9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_01a0eef3-177f-7dca-8463-01a184c7d625" xlink:to="loc_us-gaap_CreditFacilityDomain_01a0eef3-177f-74e8-bcba-37a17cc808a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredDebtMember_01a0eef3-177f-7608-8894-84417fae804b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-177f-74e8-bcba-37a17cc808a9" xlink:to="loc_us-gaap_SecuredDebtMember_01a0eef3-177f-7608-8894-84417fae804b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DelayedDrawTermLoanMember_01a0eef3-177f-74b3-8e82-d9fa87d5fb61" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DelayedDrawTermLoanMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-177f-74e8-bcba-37a17cc808a9" xlink:to="loc_us-gaap_DelayedDrawTermLoanMember_01a0eef3-177f-74b3-8e82-d9fa87d5fb61" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-177f-7f96-8cc7-e699e7f8bac8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-177f-7f96-8cc7-e699e7f8bac8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7d3a-a05e-a3c016734fbe" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-177f-7f96-8cc7-e699e7f8bac8" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7d3a-a05e-a3c016734fbe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TrancheAWarrantMember_01a0eef3-177f-7d79-afd2-86d065190df4" xlink:href="aqst-20260930.xsd#aqst_TrancheAWarrantMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7d3a-a05e-a3c016734fbe" xlink:to="loc_aqst_TrancheAWarrantMember_01a0eef3-177f-7d79-afd2-86d065190df4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis_01a0eef3-177f-71a5-8827-8468bf8f20ca" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_VariableRateAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_us-gaap_VariableRateAxis_01a0eef3-177f-71a5-8827-8468bf8f20ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_01a0eef3-177f-7537-87d3-def492cea215" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_VariableRateDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_01a0eef3-177f-71a5-8827-8468bf8f20ca" xlink:to="loc_us-gaap_VariableRateDomain_01a0eef3-177f-7537-87d3-def492cea215" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SOFRFloorMember_01a0eef3-177f-78dc-b9ce-5c2a187a9fb1" xlink:href="aqst-20260930.xsd#aqst_SOFRFloorMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_01a0eef3-177f-7537-87d3-def492cea215" xlink:to="loc_aqst_SOFRFloorMember_01a0eef3-177f-78dc-b9ce-5c2a187a9fb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredOvernightFinancingRateSofrMember_01a0eef3-177f-7b2f-b80f-a651bbe87176" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SecuredOvernightFinancingRateSofrMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_01a0eef3-177f-7537-87d3-def492cea215" xlink:to="loc_us-gaap_SecuredOvernightFinancingRateSofrMember_01a0eef3-177f-7b2f-b80f-a651bbe87176" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentEffectivePeriodAxis_01a0eef3-177f-7593-a466-2010672f7390" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentEffectivePeriodAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_aqst_DebtInstrumentEffectivePeriodAxis_01a0eef3-177f-7593-a466-2010672f7390" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentEffectivePeriodDomain_01a0eef3-177f-76c7-876d-a9419510440d" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentEffectivePeriodDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_DebtInstrumentEffectivePeriodAxis_01a0eef3-177f-7593-a466-2010672f7390" xlink:to="loc_aqst_DebtInstrumentEffectivePeriodDomain_01a0eef3-177f-76c7-876d-a9419510440d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PeriodOneMember_01a0eef3-177f-789a-82dd-441aa6d10fb4" xlink:href="aqst-20260930.xsd#aqst_PeriodOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_DebtInstrumentEffectivePeriodDomain_01a0eef3-177f-76c7-876d-a9419510440d" xlink:to="loc_aqst_PeriodOneMember_01a0eef3-177f-789a-82dd-441aa6d10fb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_01a0eef3-177f-7527-af91-b69e76143a29" xlink:to="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-177f-7f31-9515-a955f9ac45e5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-177f-7f31-9515-a955f9ac45e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_01a0eef3-177f-77a2-8182-41fec21fab94" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_01a0eef3-177f-77a2-8182-41fec21fab94" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_01a0eef3-177f-7a89-8252-58e966d36646" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_01a0eef3-177f-7a89-8252-58e966d36646" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentExitFee_01a0eef3-177f-735c-b472-6c4974122817" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentExitFee"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentExitFee_01a0eef3-177f-735c-b472-6c4974122817" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfDebt_01a0eef3-177f-749b-bf09-4c9ed1ea282f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RepaymentsOfDebt"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_RepaymentsOfDebt_01a0eef3-177f-749b-bf09-4c9ed1ea282f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentPrepaymentPenalty_01a0eef3-177f-7c8a-8148-d20d2b43fe32" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentPrepaymentPenalty"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentPrepaymentPenalty_01a0eef3-177f-7c8a-8148-d20d2b43fe32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentPrepaymentPenaltyPricePercentage_01a0eef3-177f-702c-bc3e-77dd78720d1f" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentPrepaymentPenaltyPricePercentage"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentPrepaymentPenaltyPricePercentage_01a0eef3-177f-702c-bc3e-77dd78720d1f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_01a0eef3-177f-7c90-ad1a-08dd34f51b0e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_01a0eef3-177f-7c90-ad1a-08dd34f51b0e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationPercentOfNetSales_01a0eef3-177f-71b5-8217-4a93b1f1a223" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationPercentOfNetSales"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_RoyaltyObligationPercentOfNetSales_01a0eef3-177f-71b5-8217-4a93b1f1a223" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentCovenantTieredRoyaltyPercentageTerm_01a0eef3-177f-7165-bda7-bb8c8de2b603" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentCovenantTieredRoyaltyPercentageTerm"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentCovenantTieredRoyaltyPercentageTerm_01a0eef3-177f-7165-bda7-bb8c8de2b603" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationsGross_01a0eef3-177f-7841-8dc8-f1333365d25a" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationsGross"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_RoyaltyObligationsGross_01a0eef3-177f-7841-8dc8-f1333365d25a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_01a0eef3-177f-703a-9748-7b8ad358e262" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentUnamortizedDiscount"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_01a0eef3-177f-703a-9748-7b8ad358e262" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_01a0eef3-177f-7cf6-8c17-954e12cc0ffb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_01a0eef3-177f-7cf6-8c17-954e12cc0ffb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleNumberOfEquityInstruments_01a0eef3-177f-7e66-945f-71ef39d5c3ad" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentConvertibleNumberOfEquityInstruments"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentConvertibleNumberOfEquityInstruments_01a0eef3-177f-7e66-945f-71ef39d5c3ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtFairValue_01a0eef3-177f-70fc-9e26-44af1959c443" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtFairValue"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_LongTermDebtFairValue_01a0eef3-177f-70fc-9e26-44af1959c443" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumNet_01a0eef3-177f-7445-89d3-0033bce3849a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumNet"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumNet_01a0eef3-177f-7445-89d3-0033bce3849a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_01a0eef3-177f-705c-8cce-73f33d86b089" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_01a0eef3-177f-705c-8cce-73f33d86b089" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_01a0eef3-177f-7d8c-be56-8d02b03f6932" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_01a0eef3-177f-7d8c-be56-8d02b03f6932" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfDebtDiscountPremium_01a0eef3-177f-7b3e-a2c5-baa66d53b01e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AmortizationOfDebtDiscountPremium"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_AmortizationOfDebtDiscountPremium_01a0eef3-177f-7b3e-a2c5-baa66d53b01e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_01a0eef3-177f-7ed7-b6ab-e007e5e74622" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_01a0eef3-177f-7ed7-b6ab-e007e5e74622" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LineOfCreditFacilityAvailableBorrowingCapacityIncreaseLimit_01a0eef3-177f-7499-99ec-180d4cf3cb65" xlink:href="aqst-20260930.xsd#aqst_LineOfCreditFacilityAvailableBorrowingCapacityIncreaseLimit"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_LineOfCreditFacilityAvailableBorrowingCapacityIncreaseLimit_01a0eef3-177f-7499-99ec-180d4cf3cb65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-177f-7d7b-a5c7-201a62ace151" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-177f-7d7b-a5c7-201a62ace151" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-177f-7c56-9322-0d2b3f553ed0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-177f-7c56-9322-0d2b3f553ed0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_01a0eef3-177f-7f67-aee0-ebd6f210301c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_01a0eef3-177f-7f67-aee0-ebd6f210301c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentInterestRateFloor_01a0eef3-177f-76be-b150-bfead9368777" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentInterestRateFloor"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentInterestRateFloor_01a0eef3-177f-76be-b150-bfead9368777" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_01a0eef3-177f-7c29-8f43-7e0d09b04375" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_01a0eef3-177f-7c29-8f43-7e0d09b04375" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentBasisSpreadOnVariableRateConditionalReduction_01a0eef3-177f-75e3-98b2-b64f7b2d4b8a" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentBasisSpreadOnVariableRateConditionalReduction"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentBasisSpreadOnVariableRateConditionalReduction_01a0eef3-177f-75e3-98b2-b64f7b2d4b8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentMaximumInterestRatePaidInKind_01a0eef3-177f-70d1-878a-d90095ab8da3" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentMaximumInterestRatePaidInKind"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentMaximumInterestRatePaidInKind_01a0eef3-177f-70d1-878a-d90095ab8da3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentInterestRateDefaultEventIncreaseDecrease_01a0eef3-177f-7011-8c65-8648c741d8ce" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentInterestRateDefaultEventIncreaseDecrease"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentInterestRateDefaultEventIncreaseDecrease_01a0eef3-177f-7011-8c65-8648c741d8ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentExitFeePercentage_01a0eef3-177f-761c-a80b-a6abcb7b57b9" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentExitFeePercentage"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentExitFeePercentage_01a0eef3-177f-761c-a80b-a6abcb7b57b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentInterestRateEffectivePremiumPercentage_01a0eef3-177f-702c-8529-df0075197ac4" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentInterestRateEffectivePremiumPercentage"/>
    <link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentInterestRateEffectivePremiumPercentage_01a0eef3-177f-702c-8529-df0075197ac4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentPrepaymentPremiumPercentage_01a0eef3-177f-713b-b581-4ff0b82c2c6a" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentPrepaymentPremiumPercentage"/>
    <link:presentationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentPrepaymentPremiumPercentage_01a0eef3-177f-713b-b581-4ff0b82c2c6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_DebtInstrumentUnamortizedDiscountAdditionalAdjustment_01a18625-e2ca-779e-9583-deebaee5817f" xlink:href="aqst-20260930.xsd#aqst_DebtInstrumentUnamortizedDiscountAdditionalAdjustment"/>
    <link:presentationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_aqst_DebtInstrumentUnamortizedDiscountAdditionalAdjustment_01a18625-e2ca-779e-9583-deebaee5817f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateIncreaseDecrease_01a19d23-162b-71cb-bff8-13425f8f9c69" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateIncreaseDecrease"/>
    <link:presentationArc order="34" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_01a0eef3-177f-79a5-bd5b-ed7ee86a022b" xlink:to="loc_us-gaap_DebtInstrumentInterestRateIncreaseDecrease_01a19d23-162b-71cb-bff8-13425f8f9c69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/LongTermDebtScheduleOfRoyaltyRightAgreementsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#LongTermDebtScheduleOfRoyaltyRightAgreementsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/LongTermDebtScheduleOfRoyaltyRightAgreementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-7781-bf55-3973bdfbd89f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-751f-8860-5e0ea733e76d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditFacilityTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-7781-bf55-3973bdfbd89f" xlink:to="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-751f-8860-5e0ea733e76d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_01a0eef3-177f-7083-bf35-2528e92438cf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-751f-8860-5e0ea733e76d" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_01a0eef3-177f-7083-bf35-2528e92438cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_01a0eef3-177f-77b4-9455-345dda2b04f7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_01a0eef3-177f-7083-bf35-2528e92438cf" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_01a0eef3-177f-77b4-9455-345dda2b04f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputDiscountRateMember_01a0eef3-177f-7942-a4c2-55a263e5955d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MeasurementInputDiscountRateMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_01a0eef3-177f-77b4-9455-345dda2b04f7" xlink:to="loc_us-gaap_MeasurementInputDiscountRateMember_01a0eef3-177f-7942-a4c2-55a263e5955d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MeasurementInputProbabilityOfSuccessMember_01a0eef3-177f-76e2-86b4-4e62cf04d3bf" xlink:href="aqst-20260930.xsd#aqst_MeasurementInputProbabilityOfSuccessMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_01a0eef3-177f-77b4-9455-345dda2b04f7" xlink:to="loc_aqst_MeasurementInputProbabilityOfSuccessMember_01a0eef3-177f-76e2-86b4-4e62cf04d3bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7798-8c53-3da3685c20e8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditFacilityLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-751f-8860-5e0ea733e76d" xlink:to="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7798-8c53-3da3685c20e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyAgreementMeasurementInput_01a0eef3-177f-7e6f-b047-9199c9216784" xlink:href="aqst-20260930.xsd#aqst_RoyaltyAgreementMeasurementInput"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7798-8c53-3da3685c20e8" xlink:to="loc_aqst_RoyaltyAgreementMeasurementInput_01a0eef3-177f-7e6f-b047-9199c9216784" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/LongTermDebtScheduleofTermNotesandUnamortizedDebtDiscountBalancesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#LongTermDebtScheduleofTermNotesandUnamortizedDebtDiscountBalancesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/LongTermDebtScheduleofTermNotesandUnamortizedDebtDiscountBalancesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-70b6-9963-69d6ba900dab" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-7382-bdad-49ec3c572344" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditFacilityTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-70b6-9963-69d6ba900dab" xlink:to="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-7382-bdad-49ec3c572344" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7499-8711-7b8f30ca57c1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-7382-bdad-49ec3c572344" xlink:to="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7499-8711-7b8f30ca57c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-7594-a3de-164b83eff873" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7499-8711-7b8f30ca57c1" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-7594-a3de-164b83eff873" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-177f-7703-8df9-5da6b7fdfa65" xlink:href="aqst-20260930.xsd#aqst_SeniorSecuredNotes13.5DueNovember12028Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-7594-a3de-164b83eff873" xlink:to="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-177f-7703-8df9-5da6b7fdfa65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_RoyaltyObligationsMember_01a0eef3-177f-79fc-86e7-a754ee393e64" xlink:href="aqst-20260930.xsd#aqst_RoyaltyObligationsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-7594-a3de-164b83eff873" xlink:to="loc_aqst_RoyaltyObligationsMember_01a0eef3-177f-79fc-86e7-a754ee393e64" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7d78-8de4-0fa341df5504" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-7382-bdad-49ec3c572344" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7d78-8de4-0fa341df5504" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-75ea-8a2a-d38605cda0d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7d78-8de4-0fa341df5504" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-75ea-8a2a-d38605cda0d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_01a0eef3-177f-796e-bc22-dc5c41eb371b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-75ea-8a2a-d38605cda0d9" xlink:to="loc_us-gaap_SeniorNotesMember_01a0eef3-177f-796e-bc22-dc5c41eb371b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnsecuredDebtMember_01a0eef3-177f-7192-82fa-c58bac459627" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_UnsecuredDebtMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-75ea-8a2a-d38605cda0d9" xlink:to="loc_us-gaap_UnsecuredDebtMember_01a0eef3-177f-7192-82fa-c58bac459627" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditFacilityLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_01a0eef3-177f-7382-bdad-49ec3c572344" xlink:to="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_01a0eef3-177f-7f0b-879c-f1faa58749e2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_01a0eef3-177f-7f0b-879c-f1faa58749e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_01a0eef3-177f-7ee2-9d08-d2f4c4d5ecda" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentUnamortizedDiscount"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_01a0eef3-177f-7ee2-9d08-d2f4c4d5ecda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesAndLoansPayableCurrent_01a0eef3-177f-7d64-8b35-63f5efe8239d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NotesAndLoansPayableCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:to="loc_us-gaap_NotesAndLoansPayableCurrent_01a0eef3-177f-7d64-8b35-63f5efe8239d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_01a0eef3-177f-7969-975a-8115b010efb0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:to="loc_us-gaap_LongTermDebtCurrent_01a0eef3-177f-7969-975a-8115b010efb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_01a0eef3-177f-7886-8fce-7d0f2e715c49" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_01a0eef3-177f-7886-8fce-7d0f2e715c49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_01a0eef3-177f-7a1a-ab07-a7d9f69e1fcf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:to="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_01a0eef3-177f-7a1a-ab07-a7d9f69e1fcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_01a0eef3-177f-7742-801b-076ded259d9b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtAndCapitalLeaseObligations"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_01a0eef3-177f-7afc-ac4e-31829a0dbf12" xlink:to="loc_us-gaap_LongTermDebtAndCapitalLeaseObligations_01a0eef3-177f-7742-801b-076ded259d9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/LongTermDebtScheduleofDebtMaturitiesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#LongTermDebtScheduleofDebtMaturitiesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/LongTermDebtScheduleofDebtMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-77a6-a7a5-722707c188b7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_01a0eef3-177f-7e56-afe1-64d23eb799f2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-77a6-a7a5-722707c188b7" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_01a0eef3-177f-7e56-afe1-64d23eb799f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_01a0eef3-177f-7a4a-8564-f3f963db4923" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_01a0eef3-177f-77a6-a7a5-722707c188b7" xlink:to="loc_us-gaap_LongTermDebt_01a0eef3-177f-7a4a-8564-f3f963db4923" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/WarrantsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#WarrantsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/WarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsNoteDisclosureAbstract_01a0eef3-177f-7941-893e-898a193ba7fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WarrantsAndRightsNoteDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-177f-7515-a1c2-e147ff91f362" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WarrantsAndRightsNoteDisclosureAbstract_01a0eef3-177f-7941-893e-898a193ba7fc" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-177f-7515-a1c2-e147ff91f362" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-177f-70ed-ba32-0524b2da31bc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-177f-7515-a1c2-e147ff91f362" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-177f-70ed-ba32-0524b2da31bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_01a0eef3-177f-70ed-ba32-0524b2da31bc" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TrancheAWarrantMember_01a0eef3-177f-7364-ae20-7136d3eb796f" xlink:href="aqst-20260930.xsd#aqst_TrancheAWarrantMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:to="loc_aqst_TrancheAWarrantMember_01a0eef3-177f-7364-ae20-7136d3eb796f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CommonStockWarrantsMember_01a0eef3-177f-7626-a918-3dde7cc7efc7" xlink:href="aqst-20260930.xsd#aqst_CommonStockWarrantsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:to="loc_aqst_CommonStockWarrantsMember_01a0eef3-177f-7626-a918-3dde7cc7efc7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_FirstAdditionalWarrantOfferingMember_01a0eef3-177f-791a-9be0-9f742689a5dc" xlink:href="aqst-20260930.xsd#aqst_FirstAdditionalWarrantOfferingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:to="loc_aqst_FirstAdditionalWarrantOfferingMember_01a0eef3-177f-791a-9be0-9f742689a5dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PreFundedWarrantsMember_01a0eef3-177f-7f5d-a4d2-ae6b4ebdaaf4" xlink:href="aqst-20260930.xsd#aqst_PreFundedWarrantsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:to="loc_aqst_PreFundedWarrantsMember_01a0eef3-177f-7f5d-a4d2-ae6b4ebdaaf4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ExistingWarrantsMember_01a0eef3-177f-7889-aaf0-878129586357" xlink:href="aqst-20260930.xsd#aqst_ExistingWarrantsMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:to="loc_aqst_ExistingWarrantsMember_01a0eef3-177f-7889-aaf0-878129586357" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_NewWarrantsMember_01a0eef3-177f-70a1-a0cd-60ff18476f24" xlink:href="aqst-20260930.xsd#aqst_NewWarrantsMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_01a0eef3-177f-7968-943b-7251dc04b20f" xlink:to="loc_aqst_NewWarrantsMember_01a0eef3-177f-70a1-a0cd-60ff18476f24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-177f-7fda-a163-7d3e689de0a9" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-177f-7515-a1c2-e147ff91f362" xlink:to="loc_srt_RangeAxis_01a0eef3-177f-7fda-a163-7d3e689de0a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-177f-7d83-8232-0cd202900466" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-177f-7fda-a163-7d3e689de0a9" xlink:to="loc_srt_RangeMember_01a0eef3-177f-7d83-8232-0cd202900466" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-177f-7b8b-bae5-e4d6cb21f162" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-7d83-8232-0cd202900466" xlink:to="loc_srt_MinimumMember_01a0eef3-177f-7b8b-bae5-e4d6cb21f162" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-177f-7d31-ba12-960ba8ee447c" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-7d83-8232-0cd202900466" xlink:to="loc_srt_MaximumMember_01a0eef3-177f-7d31-ba12-960ba8ee447c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7f4b-bbd8-c4d96032d599" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-177f-7515-a1c2-e147ff91f362" xlink:to="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7f4b-bbd8-c4d96032d599" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-72ad-932c-ab31c0c1ae34" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_01a0eef3-177f-7f4b-bbd8-c4d96032d599" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-72ad-932c-ab31c0c1ae34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TwelvePointFiveSeniorSecuredNotesDueJune302025Member_01a0eef3-177f-7354-9bf9-cc33447e77a5" xlink:href="aqst-20260930.xsd#aqst_TwelvePointFiveSeniorSecuredNotesDueJune302025Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-72ad-932c-ab31c0c1ae34" xlink:to="loc_aqst_TwelvePointFiveSeniorSecuredNotesDueJune302025Member_01a0eef3-177f-7354-9bf9-cc33447e77a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_A2020AdditionalNotesMember_01a0eef3-177f-78bd-abe3-22d33615d7ed" xlink:href="aqst-20260930.xsd#aqst_A2020AdditionalNotesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-72ad-932c-ab31c0c1ae34" xlink:to="loc_aqst_A2020AdditionalNotesMember_01a0eef3-177f-78bd-abe3-22d33615d7ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-177f-7291-9ba8-403d13847796" xlink:href="aqst-20260930.xsd#aqst_SeniorSecuredNotes13.5DueNovember12028Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-72ad-932c-ab31c0c1ae34" xlink:to="loc_aqst_SeniorSecuredNotes13.5DueNovember12028Member_01a0eef3-177f-7291-9ba8-403d13847796" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_OaktreeCapitalManagementLPMember_01a11ae8-3223-7114-9dff-9634a0034f52" xlink:href="aqst-20260930.xsd#aqst_OaktreeCapitalManagementLPMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_01a0eef3-177f-72ad-932c-ab31c0c1ae34" xlink:to="loc_aqst_OaktreeCapitalManagementLPMember_01a11ae8-3223-7114-9dff-9634a0034f52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7ac6-b14f-5389633bca47" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-177f-7515-a1c2-e147ff91f362" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7ac6-b14f-5389633bca47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e92-afcc-24a41ccccf58" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_01a0eef3-177f-7ac6-b14f-5389633bca47" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e92-afcc-24a41ccccf58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_01a0eef3-177f-7284-b2dd-b9923d509258" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e92-afcc-24a41ccccf58" xlink:to="loc_us-gaap_SeniorNotesMember_01a0eef3-177f-7284-b2dd-b9923d509258" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditMember_01a11ae8-3223-79a9-9b0e-bb32f0c4cb86" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LineOfCreditMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_01a0eef3-177f-7e92-afcc-24a41ccccf58" xlink:to="loc_us-gaap_LineOfCreditMember_01a11ae8-3223-79a9-9b0e-bb32f0c4cb86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_01a0eef3-177f-7515-a1c2-e147ff91f362" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-177f-77b3-af11-9558baa13f39" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_01a0eef3-177f-77b3-af11-9558baa13f39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-177f-7b89-8e99-6c8a7b731c06" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_01a0eef3-177f-7b89-8e99-6c8a7b731c06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_01a0eef3-177f-7ef0-a3f3-0cdb46931925" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_01a0eef3-177f-7ef0-a3f3-0cdb46931925" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingTerm_01a0eef3-177f-7944-87e5-e8cc6128182e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WarrantsAndRightsOutstandingTerm"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingTerm_01a0eef3-177f-7944-87e5-e8cc6128182e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-177f-769a-bd9f-96318c73467c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_01a0eef3-177f-769a-bd9f-96318c73467c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AdjustmentsToAdditionalPaidInCapitalFairValueOfWarrantsIssued_01a0eef3-177f-78ab-9e8d-277ad04733a6" xlink:href="aqst-20260930.xsd#aqst_AdjustmentsToAdditionalPaidInCapitalFairValueOfWarrantsIssued"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_aqst_AdjustmentsToAdditionalPaidInCapitalFairValueOfWarrantsIssued_01a0eef3-177f-78ab-9e8d-277ad04733a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ClassOfWarrantOrRightWarrantsIssuedDuringPeriod_01a0eef3-177f-7bb0-93f8-4167a9495152" xlink:href="aqst-20260930.xsd#aqst_ClassOfWarrantOrRightWarrantsIssuedDuringPeriod"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_aqst_ClassOfWarrantOrRightWarrantsIssuedDuringPeriod_01a0eef3-177f-7bb0-93f8-4167a9495152" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromWarrantExercises_01a0eef3-177f-713b-a08e-58938efaaa2c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromWarrantExercises"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_ProceedsFromWarrantExercises_01a0eef3-177f-713b-a08e-58938efaaa2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_01a0eef3-177f-7d64-8ef1-916c25efd91c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_01a0eef3-177f-7d64-8ef1-916c25efd91c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ClassOfWarrantOrRightWarrantsExercised_01a0eef3-177f-7790-919a-921e57b3da02" xlink:href="aqst-20260930.xsd#aqst_ClassOfWarrantOrRightWarrantsExercised"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_aqst_ClassOfWarrantOrRightWarrantsExercised_01a0eef3-177f-7790-919a-921e57b3da02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_01a15842-52c9-79f2-92bb-62986157ea0f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_01a0eef3-177f-7783-94d7-614b84f881ad" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_01a15842-52c9-79f2-92bb-62986157ea0f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromWarrantExercises_01a1981c-2bb0-71a3-b402-db107554aaba" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromWarrantExercises"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SaleofFutureRevenueNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#SaleofFutureRevenueNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SaleofFutureRevenueNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-750d-8055-cb21100dce48" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7928-9f84-3627371fdd34" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-750d-8055-cb21100dce48" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7928-9f84-3627371fdd34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_01a0eef3-177f-79c6-915f-020f190575be" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7928-9f84-3627371fdd34" xlink:to="loc_us-gaap_CreditFacilityAxis_01a0eef3-177f-79c6-915f-020f190575be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_01a0eef3-177f-7701-911c-5868d3ab1e16" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CreditFacilityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_01a0eef3-177f-79c6-915f-020f190575be" xlink:to="loc_us-gaap_CreditFacilityDomain_01a0eef3-177f-7701-911c-5868d3ab1e16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MonetizationAgreementMember_01a0eef3-177f-7e60-8aba-04a4faddf04b" xlink:href="aqst-20260930.xsd#aqst_MonetizationAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_01a0eef3-177f-7701-911c-5868d3ab1e16" xlink:to="loc_aqst_MonetizationAgreementMember_01a0eef3-177f-7e60-8aba-04a4faddf04b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-177f-77c6-90a7-1e5dfc93d1e5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7928-9f84-3627371fdd34" xlink:to="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-177f-77c6-90a7-1e5dfc93d1e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-177f-74e2-b9fe-88f2ed79e4f9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_01a0eef3-177f-77c6-90a7-1e5dfc93d1e5" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-177f-74e2-b9fe-88f2ed79e4f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MarathonPangolinRoyaltyLLCMember_01a0eef3-177f-77e6-9f4b-f27ae80c5c83" xlink:href="aqst-20260930.xsd#aqst_MarathonPangolinRoyaltyLLCMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-177f-74e2-b9fe-88f2ed79e4f9" xlink:to="loc_aqst_MarathonPangolinRoyaltyLLCMember_01a0eef3-177f-77e6-9f4b-f27ae80c5c83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember_01a0eef3-177f-72b4-82a5-76fa76c184b5" xlink:href="aqst-20260930.xsd#aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a0eef3-177f-74e2-b9fe-88f2ed79e4f9" xlink:to="loc_aqst_LicenseAgreementWithSunovionPharmaceuticalsIncMember_01a0eef3-177f-72b4-82a5-76fa76c184b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-177f-7a55-b89a-7f201999fdfd" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7928-9f84-3627371fdd34" xlink:to="loc_srt_RangeAxis_01a0eef3-177f-7a55-b89a-7f201999fdfd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-177f-7233-8821-55168d5b307e" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-177f-7a55-b89a-7f201999fdfd" xlink:to="loc_srt_RangeMember_01a0eef3-177f-7233-8821-55168d5b307e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-177f-74c8-af08-1ada7732edd1" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-7233-8821-55168d5b307e" xlink:to="loc_srt_MaximumMember_01a0eef3-177f-74c8-af08-1ada7732edd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_01a0eef3-177f-7134-939f-49f2b96c84bb" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7928-9f84-3627371fdd34" xlink:to="loc_srt_ProductOrServiceAxis_01a0eef3-177f-7134-939f-49f2b96c84bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-7cc3-a45f-f45111a11633" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_01a0eef3-177f-7134-939f-49f2b96c84bb" xlink:to="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-7cc3-a45f-f45111a11633" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RoyaltyMember_01a0eef3-177f-7384-9b77-b7deb90bfa38" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RoyaltyMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-7cc3-a45f-f45111a11633" xlink:to="loc_us-gaap_RoyaltyMember_01a0eef3-177f-7384-9b77-b7deb90bfa38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7928-9f84-3627371fdd34" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ProceedsFromSaleOfFutureRevenuesNet_01a0eef3-177f-7be8-b3ad-e66e8164b673" xlink:href="aqst-20260930.xsd#aqst_ProceedsFromSaleOfFutureRevenuesNet"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:to="loc_aqst_ProceedsFromSaleOfFutureRevenuesNet_01a0eef3-177f-7be8-b3ad-e66e8164b673" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ContingentMonetizationAgreementMilestonePayment_01a0eef3-177f-7c2d-8a0f-71033d15f7e5" xlink:href="aqst-20260930.xsd#aqst_ContingentMonetizationAgreementMilestonePayment"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:to="loc_aqst_ContingentMonetizationAgreementMilestonePayment_01a0eef3-177f-7c2d-8a0f-71033d15f7e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfFinancingCosts_01a0eef3-177f-727d-8249-51f89f1e5485" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsOfFinancingCosts"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:to="loc_us-gaap_PaymentsOfFinancingCosts_01a0eef3-177f-727d-8249-51f89f1e5485" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-177f-7767-bce6-1f0c5abc7378" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-177f-7767-bce6-1f0c5abc7378" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MinimumAnnualRoyaltyReceivable_01a0eef3-177f-7fb0-b906-db96d0872bec" xlink:href="aqst-20260930.xsd#aqst_MinimumAnnualRoyaltyReceivable"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:to="loc_aqst_MinimumAnnualRoyaltyReceivable_01a0eef3-177f-7fb0-b906-db96d0872bec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_01a0eef3-177f-7e82-9677-5c3856fd352d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-731e-a515-8c29679b3893" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_01a0eef3-177f-7e82-9677-5c3856fd352d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SaleofFutureRevenueScheduleofRoyaltyObligationDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#SaleofFutureRevenueScheduleofRoyaltyObligationDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SaleofFutureRevenueScheduleofRoyaltyObligationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-72ad-9941-38d8d39fee30" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7c66-b1cc-251eb79ebdae" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_01a0eef3-177f-72ad-9941-38d8d39fee30" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7c66-b1cc-251eb79ebdae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_01a0eef3-177f-760b-9d81-6c12d4e37faa" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7c66-b1cc-251eb79ebdae" xlink:to="loc_srt_ProductOrServiceAxis_01a0eef3-177f-760b-9d81-6c12d4e37faa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-75a0-908c-c06f86d0d0f9" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_01a0eef3-177f-760b-9d81-6c12d4e37faa" xlink:to="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-75a0-908c-c06f86d0d0f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RoyaltyMember_01a0eef3-177f-728d-9592-8bade9b64868" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RoyaltyMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_01a0eef3-177f-75a0-908c-c06f86d0d0f9" xlink:to="loc_us-gaap_RoyaltyMember_01a0eef3-177f-728d-9592-8bade9b64868" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-72a4-9df3-01686a28fe75" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_01a0eef3-177f-7c66-b1cc-251eb79ebdae" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-72a4-9df3-01686a28fe75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SaleOfFutureRevenueRollForward_01a0eef3-177f-7287-b864-8bf87a38a119" xlink:href="aqst-20260930.xsd#aqst_SaleOfFutureRevenueRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-72a4-9df3-01686a28fe75" xlink:to="loc_aqst_SaleOfFutureRevenueRollForward_01a0eef3-177f-7287-b864-8bf87a38a119" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LiabilitiesSaleOfFutureRoyalties_01a0eef3-177f-701f-b96e-66ec1fa73132" xlink:href="aqst-20260930.xsd#aqst_LiabilitiesSaleOfFutureRoyalties"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_SaleOfFutureRevenueRollForward_01a0eef3-177f-7287-b864-8bf87a38a119" xlink:to="loc_aqst_LiabilitiesSaleOfFutureRoyalties_01a0eef3-177f-701f-b96e-66ec1fa73132" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-177f-737b-9742-2e6c1afa7b62" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_SaleOfFutureRevenueRollForward_01a0eef3-177f-7287-b864-8bf87a38a119" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_01a0eef3-177f-737b-9742-2e6c1afa7b62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedNetLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCosts_01a0eef3-177f-74a3-b301-dc21939f42b9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AmortizationOfFinancingCosts"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_SaleOfFutureRevenueRollForward_01a0eef3-177f-7287-b864-8bf87a38a119" xlink:to="loc_us-gaap_AmortizationOfFinancingCosts_01a0eef3-177f-74a3-b301-dc21939f42b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LiabilitiesSaleOfFutureRoyalties_01a0eef3-177f-7e44-89de-132f1e77834e" xlink:href="aqst-20260930.xsd#aqst_LiabilitiesSaleOfFutureRoyalties"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_SaleOfFutureRevenueRollForward_01a0eef3-177f-7287-b864-8bf87a38a119" xlink:to="loc_aqst_LiabilitiesSaleOfFutureRoyalties_01a0eef3-177f-7e44-89de-132f1e77834e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedCurrent_01a0eef3-177f-755a-9aca-44828cd4ef83" xlink:href="aqst-20260930.xsd#aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_01a0eef3-177f-72a4-9df3-01686a28fe75" xlink:to="loc_aqst_TransferOfFinancialAssetsAccountedForAsSalesAmountDerecognizedCurrent_01a0eef3-177f-755a-9aca-44828cd4ef83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNonCurrentLiabilitiesNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNonCurrentLiabilitiesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNonCurrentLiabilitiesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-7160-ba82-09d29e6867ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligation_01a0eef3-177f-77b4-980f-fd3a4b7eef06" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-7160-ba82-09d29e6867ff" xlink:to="loc_us-gaap_AssetRetirementObligation_01a0eef3-177f-77b4-980f-fd3a4b7eef06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AssetRetirementObligationsDepreciationExpense_01a0eef3-177f-7868-ae03-8062d179d856" xlink:href="aqst-20260930.xsd#aqst_AssetRetirementObligationsDepreciationExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-7160-ba82-09d29e6867ff" xlink:to="loc_aqst_AssetRetirementObligationsDepreciationExpense_01a0eef3-177f-7868-ae03-8062d179d856" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/OtherNonCurrentLiabilitiesScheduleofLiabilityforAssetRetirementObligationsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#OtherNonCurrentLiabilitiesScheduleofLiabilityforAssetRetirementObligationsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/OtherNonCurrentLiabilitiesScheduleofLiabilityforAssetRetirementObligationsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-7ce0-a67a-adaa7d027993" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward_01a0eef3-177f-7d8f-aaa0-813a75b1dea4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationDisclosureAbstract_01a0eef3-177f-7ce0-a67a-adaa7d027993" xlink:to="loc_us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward_01a0eef3-177f-7d8f-aaa0-813a75b1dea4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligation_01a0eef3-177f-727a-82ac-b780fd0914ad" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward_01a0eef3-177f-7d8f-aaa0-813a75b1dea4" xlink:to="loc_us-gaap_AssetRetirementObligation_01a0eef3-177f-727a-82ac-b780fd0914ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationLiabilitiesIncurred_01a0eef3-177f-7f02-8151-643867ff9848" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationLiabilitiesIncurred"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward_01a0eef3-177f-7d8f-aaa0-813a75b1dea4" xlink:to="loc_us-gaap_AssetRetirementObligationLiabilitiesIncurred_01a0eef3-177f-7f02-8151-643867ff9848" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligationAccretionExpense_01a0eef3-177f-787a-b396-d1c604b05d01" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligationAccretionExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward_01a0eef3-177f-7d8f-aaa0-813a75b1dea4" xlink:to="loc_us-gaap_AssetRetirementObligationAccretionExpense_01a0eef3-177f-787a-b396-d1c604b05d01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AssetRetirementObligationReclassificationToAccountsPayable_01a13e4d-9dcc-7056-8a3f-47d8a3b8b1f6" xlink:href="aqst-20260930.xsd#aqst_AssetRetirementObligationReclassificationToAccountsPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward_01a0eef3-177f-7d8f-aaa0-813a75b1dea4" xlink:to="loc_aqst_AssetRetirementObligationReclassificationToAccountsPayable_01a13e4d-9dcc-7056-8a3f-47d8a3b8b1f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetRetirementObligation_01a0eef3-177f-7039-b3cc-cab0885d88dd" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetRetirementObligation"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetRetirementObligationRollForwardAnalysisRollForward_01a0eef3-177f-7d8f-aaa0-813a75b1dea4" xlink:to="loc_us-gaap_AssetRetirementObligation_01a0eef3-177f-7039-b3cc-cab0885d88dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/NetLossPerShareDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#NetLossPerShareDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/NetLossPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-177f-7f56-8d9d-fb052033bb24" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_01a0eef3-177f-762d-8dbe-68f16fd2c21a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_01a0eef3-177f-7f56-8d9d-fb052033bb24" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_01a0eef3-177f-762d-8dbe-68f16fd2c21a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_01a0eef3-177f-743e-945b-fba17721c0c2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_01a0eef3-177f-762d-8dbe-68f16fd2c21a" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_01a0eef3-177f-743e-945b-fba17721c0c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_01a0eef3-177f-7c2f-b014-c91dfd73b9d5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_01a0eef3-177f-743e-945b-fba17721c0c2" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_01a0eef3-177f-7c2f-b014-c91dfd73b9d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-177f-7312-9b31-37341c3b3fbb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_01a0eef3-177f-7c2f-b014-c91dfd73b9d5" xlink:to="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-177f-7312-9b31-37341c3b3fbb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-7b5f-b112-a815204992b7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_01a0eef3-177f-7c2f-b014-c91dfd73b9d5" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-7b5f-b112-a815204992b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_01a0eef3-177f-7b20-b3b0-4fa290bf6db4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_01a0eef3-177f-7c2f-b014-c91dfd73b9d5" xlink:to="loc_us-gaap_WarrantMember_01a0eef3-177f-7b20-b3b0-4fa290bf6db4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_01a0eef3-177f-7653-9df5-7a59ae079ac8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_01a0eef3-177f-762d-8dbe-68f16fd2c21a" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_01a0eef3-177f-7653-9df5-7a59ae079ac8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UndistributedEarningsAbstract_01a0eef3-177f-757c-ac4b-d3ff5516647b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_UndistributedEarningsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_01a0eef3-177f-7653-9df5-7a59ae079ac8" xlink:to="loc_us-gaap_UndistributedEarningsAbstract_01a0eef3-177f-757c-ac4b-d3ff5516647b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_01a0eef3-177f-75c7-a9e1-bc00b6b9ab20" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_UndistributedEarningsAbstract_01a0eef3-177f-757c-ac4b-d3ff5516647b" xlink:to="loc_us-gaap_NetIncomeLoss_01a0eef3-177f-75c7-a9e1-bc00b6b9ab20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_01a0eef3-177f-7986-9a21-fad664db376b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_01a0eef3-177f-7653-9df5-7a59ae079ac8" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_01a0eef3-177f-7986-9a21-fad664db376b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_01a0eef3-177f-7f37-a89b-33f904660e5c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_01a0eef3-177f-7986-9a21-fad664db376b" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_01a0eef3-177f-7f37-a89b-33f904660e5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_01a0eef3-177f-7b03-8c59-fa9c98d2114f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_01a0eef3-177f-7986-9a21-fad664db376b" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_01a0eef3-177f-7b03-8c59-fa9c98d2114f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_01a0eef3-177f-70f8-9777-2cd8153e0d66" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_01a0eef3-177f-7986-9a21-fad664db376b" xlink:to="loc_us-gaap_EarningsPerShareBasic_01a0eef3-177f-70f8-9777-2cd8153e0d66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_01a0eef3-177f-7760-8876-baa008ef4acc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_01a0eef3-177f-7986-9a21-fad664db376b" xlink:to="loc_us-gaap_EarningsPerShareDiluted_01a0eef3-177f-7760-8876-baa008ef4acc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_01a0eef3-177f-77ca-8bc3-6033bbcee58d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_01a0eef3-177f-7653-9df5-7a59ae079ac8" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_01a0eef3-177f-77ca-8bc3-6033bbcee58d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ShareBasedCompensationScheduleofShareBasedCompensationExpenseDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#ShareBasedCompensationScheduleofShareBasedCompensationExpenseDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ShareBasedCompensationScheduleofShareBasedCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7fab-ba8e-376815e2c5a3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-72b8-82b3-fa0824bc607e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-7fab-ba8e-376815e2c5a3" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-72b8-82b3-fa0824bc607e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeLocationBalanceAxis_01a0eef3-177f-77a9-8a79-c5b9e9ca82e3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StatementOfIncomeLocationBalanceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-72b8-82b3-fa0824bc607e" xlink:to="loc_us-gaap_StatementOfIncomeLocationBalanceAxis_01a0eef3-177f-77a9-8a79-c5b9e9ca82e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-79bd-b559-25cadf1a014a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-72b8-82b3-fa0824bc607e" xlink:to="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-79bd-b559-25cadf1a014a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7cb6-9e22-6d7359b399ee" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-79bd-b559-25cadf1a014a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7cb6-9e22-6d7359b399ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-7fe2-ae73-3c28223681a2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7cb6-9e22-6d7359b399ee" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-7fe2-ae73-3c28223681a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-177f-70e1-a957-64b90c773cea" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7cb6-9e22-6d7359b399ee" xlink:to="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-177f-70e1-a957-64b90c773cea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_01a0eef3-177f-74c7-a417-696bd320a56a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7cb6-9e22-6d7359b399ee" xlink:to="loc_us-gaap_EmployeeStockMember_01a0eef3-177f-74c7-a417-696bd320a56a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-7ef8-b813-2447ee854561" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-72b8-82b3-fa0824bc607e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-7ef8-b813-2447ee854561" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAbstract_01a0eef3-177f-7a3d-840d-4e3354acf0a2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-7ef8-b813-2447ee854561" xlink:to="loc_us-gaap_ShareBasedCompensationAbstract_01a0eef3-177f-7a3d-840d-4e3354acf0a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_01a0eef3-177f-7055-b5ed-cf4c45f1563d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationAbstract_01a0eef3-177f-7a3d-840d-4e3354acf0a2" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_01a0eef3-177f-7055-b5ed-cf4c45f1563d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ShareBasedCompensationScheduleofRestrictedStockUnitsAwardsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#ShareBasedCompensationScheduleofRestrictedStockUnitsAwardsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ShareBasedCompensationScheduleofRestrictedStockUnitsAwardsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-776f-bd7a-eab940b3c6de" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7fcb-9ec2-d3236e12cd42" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-776f-bd7a-eab940b3c6de" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7fcb-9ec2-d3236e12cd42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-7e2d-bb85-89ec06e223bb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7fcb-9ec2-d3236e12cd42" xlink:to="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-7e2d-bb85-89ec06e223bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7501-a465-b87f505bcc7d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-7e2d-bb85-89ec06e223bb" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7501-a465-b87f505bcc7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-787f-9b82-6b0d82746eaa" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7501-a465-b87f505bcc7d" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-787f-9b82-6b0d82746eaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_01a0eef3-177f-7217-9195-81c517da0f5a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7fcb-9ec2-d3236e12cd42" xlink:to="loc_us-gaap_PlanNameAxis_01a0eef3-177f-7217-9195-81c517da0f5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7ce8-bbe9-ed57fefdb6ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_01a0eef3-177f-7217-9195-81c517da0f5a" xlink:to="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7ce8-bbe9-ed57fefdb6ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ServiceBasedMember_01a0eef3-177f-702f-af53-21c00b6d39ec" xlink:href="aqst-20260930.xsd#aqst_ServiceBasedMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7ce8-bbe9-ed57fefdb6ff" xlink:to="loc_aqst_ServiceBasedMember_01a0eef3-177f-702f-af53-21c00b6d39ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MarketBasedMember_01a0eef3-177f-7c03-be24-b497b58dceb8" xlink:href="aqst-20260930.xsd#aqst_MarketBasedMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7ce8-bbe9-ed57fefdb6ff" xlink:to="loc_aqst_MarketBasedMember_01a0eef3-177f-7c03-be24-b497b58dceb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-79dc-9d46-f09b10098680" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7fcb-9ec2-d3236e12cd42" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-79dc-9d46-f09b10098680" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_01a0eef3-177f-7d8e-ac14-9bf72161d48a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-79dc-9d46-f09b10098680" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_01a0eef3-177f-7d8e-ac14-9bf72161d48a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_01a0eef3-177f-7eef-a913-4badec30ae2b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_01a0eef3-177f-7d8e-ac14-9bf72161d48a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_01a0eef3-177f-7eef-a913-4badec30ae2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_01a0eef3-177f-7916-9d7a-c8603ca2eb19" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_01a0eef3-177f-7d8e-ac14-9bf72161d48a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_01a0eef3-177f-7916-9d7a-c8603ca2eb19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_01a0eef3-177f-708f-8781-420bfe3f673e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_01a0eef3-177f-7d8e-ac14-9bf72161d48a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_01a0eef3-177f-708f-8781-420bfe3f673e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_01a0eef3-177f-7874-965c-cf1c3ea91ffa" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_01a0eef3-177f-7d8e-ac14-9bf72161d48a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_01a0eef3-177f-7874-965c-cf1c3ea91ffa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_01a0eef3-177f-782d-b2aa-080110fe5e2d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_01a0eef3-177f-7d8e-ac14-9bf72161d48a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_01a0eef3-177f-782d-b2aa-080110fe5e2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInShares_01a0eef3-177f-7752-ad0c-c7920ae7b2e7" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInShares"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-79dc-9d46-f09b10098680" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInShares_01a0eef3-177f-7752-ad0c-c7920ae7b2e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_01a0eef3-177f-766a-a7ff-a2a345cde287" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-79dc-9d46-f09b10098680" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_01a0eef3-177f-766a-a7ff-a2a345cde287" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_01a0eef3-177f-7c4c-b352-2fb661236266" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_01a0eef3-177f-766a-a7ff-a2a345cde287" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_01a0eef3-177f-7c4c-b352-2fb661236266" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_01a0eef3-177f-7b04-97e4-68cd678591f6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_01a0eef3-177f-766a-a7ff-a2a345cde287" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_01a0eef3-177f-7b04-97e4-68cd678591f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_01a0eef3-177f-77d9-ae7e-f47708d0c07e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_01a0eef3-177f-766a-a7ff-a2a345cde287" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_01a0eef3-177f-77d9-ae7e-f47708d0c07e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_01a0eef3-177f-7b16-a998-9d1e965d8fb3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_01a0eef3-177f-766a-a7ff-a2a345cde287" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_01a0eef3-177f-7b16-a998-9d1e965d8fb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_01a0eef3-177f-79a3-b04a-9640de1da7b5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_01a0eef3-177f-766a-a7ff-a2a345cde287" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_01a0eef3-177f-79a3-b04a-9640de1da7b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsEstimatedGrantDateFairValue_01a0eef3-177f-7cfb-a28a-be428d84c36b" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsEstimatedGrantDateFairValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-79dc-9d46-f09b10098680" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsEstimatedGrantDateFairValue_01a0eef3-177f-7cfb-a28a-be428d84c36b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRightsPercentageOfAwardVested_01a0eef3-177f-7cde-befd-aeede99864ce" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRightsPercentageOfAwardVested"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-177f-79dc-9d46-f09b10098680" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingRightsPercentageOfAwardVested_01a0eef3-177f-7cde-befd-aeede99864ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ShareBasedCompensationNarrativeDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#ShareBasedCompensationNarrativeDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ShareBasedCompensationNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-797e-a1d6-63b30d78c7ee" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7115-a087-92c437d232d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-177f-797e-a1d6-63b30d78c7ee" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7115-a087-92c437d232d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-7fa4-8a39-f6d0f17426f7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7115-a087-92c437d232d9" xlink:to="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-7fa4-8a39-f6d0f17426f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7f86-9ad9-67a345a4c271" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_01a0eef3-177f-7fa4-8a39-f6d0f17426f7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7f86-9ad9-67a345a4c271" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-78cd-a2a6-d9294ec797a8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7f86-9ad9-67a345a4c271" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_01a0eef3-177f-78cd-a2a6-d9294ec797a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PerformanceSharesMember_01a0eef3-177f-7d96-bbb1-93139027a4f2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PerformanceSharesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7f86-9ad9-67a345a4c271" xlink:to="loc_us-gaap_PerformanceSharesMember_01a0eef3-177f-7d96-bbb1-93139027a4f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-177f-70c0-b591-e73c98431d87" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-177f-7f86-9ad9-67a345a4c271" xlink:to="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-177f-70c0-b591-e73c98431d87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_01a0eef3-177f-79ac-9f1f-b05b87d7d911" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7115-a087-92c437d232d9" xlink:to="loc_us-gaap_PlanNameAxis_01a0eef3-177f-79ac-9f1f-b05b87d7d911" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7606-ad0a-fc7b59fec99e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_01a0eef3-177f-79ac-9f1f-b05b87d7d911" xlink:to="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7606-ad0a-fc7b59fec99e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ServiceBasedMember_01a0eef3-177f-7f24-b12d-d324557179fb" xlink:href="aqst-20260930.xsd#aqst_ServiceBasedMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7606-ad0a-fc7b59fec99e" xlink:to="loc_aqst_ServiceBasedMember_01a0eef3-177f-7f24-b12d-d324557179fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_MarketBasedMember_01a0eef3-177f-70a3-b32e-52f0524e3f9b" xlink:href="aqst-20260930.xsd#aqst_MarketBasedMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7606-ad0a-fc7b59fec99e" xlink:to="loc_aqst_MarketBasedMember_01a0eef3-177f-70a3-b32e-52f0524e3f9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_A2023MarketBasedMember_01a1a261-0a0e-7069-99ea-3a4352b59d62" xlink:href="aqst-20260930.xsd#aqst_A2023MarketBasedMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7606-ad0a-fc7b59fec99e" xlink:to="loc_aqst_A2023MarketBasedMember_01a1a261-0a0e-7069-99ea-3a4352b59d62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_A2025MarketBasedMember_01a0eef3-177f-706e-bc10-07846803fd3b" xlink:href="aqst-20260930.xsd#aqst_A2025MarketBasedMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7606-ad0a-fc7b59fec99e" xlink:to="loc_aqst_A2025MarketBasedMember_01a0eef3-177f-706e-bc10-07846803fd3b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_A2022InducementEquityIncentivePlanMember_01a0eef3-177f-717d-8796-ada0c6d51a4c" xlink:href="aqst-20260930.xsd#aqst_A2022InducementEquityIncentivePlanMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01a0eef3-177f-7606-ad0a-fc7b59fec99e" xlink:to="loc_aqst_A2022InducementEquityIncentivePlanMember_01a0eef3-177f-717d-8796-ada0c6d51a4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-177f-79a4-a077-a8c659108eb5" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7115-a087-92c437d232d9" xlink:to="loc_srt_RangeAxis_01a0eef3-177f-79a4-a077-a8c659108eb5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-177f-785e-970f-0ee04e2aa2b9" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-177f-79a4-a077-a8c659108eb5" xlink:to="loc_srt_RangeMember_01a0eef3-177f-785e-970f-0ee04e2aa2b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-177f-76e6-a07f-90a938637f05" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-785e-970f-0ee04e2aa2b9" xlink:to="loc_srt_MinimumMember_01a0eef3-177f-76e6-a07f-90a938637f05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-177f-771d-928e-d1e921c32bd6" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-177f-785e-970f-0ee04e2aa2b9" xlink:to="loc_srt_MaximumMember_01a0eef3-177f-771d-928e-d1e921c32bd6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionAxis_01a0eef3-177f-7791-bc9a-f670731177f4" xlink:href="aqst-20260930.xsd#aqst_VestingConditionAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7115-a087-92c437d232d9" xlink:to="loc_aqst_VestingConditionAxis_01a0eef3-177f-7791-bc9a-f670731177f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:href="aqst-20260930.xsd#aqst_VestingConditionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_VestingConditionAxis_01a0eef3-177f-7791-bc9a-f670731177f4" xlink:to="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionRangeSevenMember_01a0eef3-177f-7c44-b458-09d381690026" xlink:href="aqst-20260930.xsd#aqst_VestingConditionRangeSevenMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:to="loc_aqst_VestingConditionRangeSevenMember_01a0eef3-177f-7c44-b458-09d381690026" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionRangeEightMember_01a0eef3-177f-7563-85fa-d8c6be9e3c7c" xlink:href="aqst-20260930.xsd#aqst_VestingConditionRangeEightMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:to="loc_aqst_VestingConditionRangeEightMember_01a0eef3-177f-7563-85fa-d8c6be9e3c7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionRangeNineMember_01a0eef3-177f-7cb5-90f1-bcc04d1f17a7" xlink:href="aqst-20260930.xsd#aqst_VestingConditionRangeNineMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:to="loc_aqst_VestingConditionRangeNineMember_01a0eef3-177f-7cb5-90f1-bcc04d1f17a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionRangeTenMember_01a0eef3-1780-7c5c-80f0-0e0bd6bb4474" xlink:href="aqst-20260930.xsd#aqst_VestingConditionRangeTenMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:to="loc_aqst_VestingConditionRangeTenMember_01a0eef3-1780-7c5c-80f0-0e0bd6bb4474" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionRangeElevenMember_01a0eef3-1780-73cc-b6ed-d66998807c74" xlink:href="aqst-20260930.xsd#aqst_VestingConditionRangeElevenMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:to="loc_aqst_VestingConditionRangeElevenMember_01a0eef3-1780-73cc-b6ed-d66998807c74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_VestingConditionRangeTwelveMember_01a0eef3-1780-75de-9e8c-d6d47508aa89" xlink:href="aqst-20260930.xsd#aqst_VestingConditionRangeTwelveMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_VestingConditionDomain_01a0eef3-177f-7a9a-a436-748ffd63d7ca" xlink:to="loc_aqst_VestingConditionRangeTwelveMember_01a0eef3-1780-75de-9e8c-d6d47508aa89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-177f-7115-a087-92c437d232d9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_01a0eef3-1780-78c2-9e20-60e5ef5e222e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_01a0eef3-1780-78c2-9e20-60e5ef5e222e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_01a0eef3-1780-729f-b54f-c40f71bf1a76" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_01a0eef3-1780-729f-b54f-c40f71bf1a76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_01a0eef3-1780-7d57-b55a-53f55466e52b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_01a0eef3-1780-7d57-b55a-53f55466e52b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAverageClosingPricesPeriod_01a0eef3-1780-7fdf-9281-d945887c0bb2" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAverageClosingPricesPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAverageClosingPricesPeriod_01a0eef3-1780-7fdf-9281-d945887c0bb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentMarketConditionPerformancePriceThresholdPerShare_01a0eef3-1780-770e-a6a2-48e3beb9cc19" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentMarketConditionPerformancePriceThresholdPerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentMarketConditionPerformancePriceThresholdPerShare_01a0eef3-1780-770e-a6a2-48e3beb9cc19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_01a0eef3-1780-77ff-96ea-93b1e7ebbe11" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_01a0eef3-1780-77ff-96ea-93b1e7ebbe11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPricingPeriods_01a0eef3-1780-774c-b4d7-74a4cb564caa" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPricingPeriods"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPricingPeriods_01a0eef3-1780-774c-b4d7-74a4cb564caa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsDaysUtilizedInPricingPeriod_01a0eef3-1780-7e7c-8b99-060e1df056cc" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsDaysUtilizedInPricingPeriod"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsDaysUtilizedInPricingPeriod_01a0eef3-1780-7e7c-8b99-060e1df056cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_01a0eef3-1780-76a4-be80-c83974622862" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_01a0eef3-1780-76a4-be80-c83974622862" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_01a0eef3-1780-7da1-8430-392b6cb2a064" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_01a0eef3-1780-7da1-8430-392b6cb2a064" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_01a0eef3-1780-7e6d-b0c0-4d3dc43e2c79" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_01a0eef3-1780-7e6d-b0c0-4d3dc43e2c79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_01a0eef3-1780-7ffb-b749-4cd141be8b38" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_01a0eef3-1780-7ffb-b749-4cd141be8b38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_01a0eef3-1780-7c3a-b995-8c62dab02890" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_01a0eef3-1780-7c3a-b995-8c62dab02890" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_01a0eef3-1780-74b4-aa26-fc812be7ca9f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7fe1-9a4a-713f1f8fb395" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_01a0eef3-1780-74b4-aa26-fc812be7ca9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ShareBasedCompensationScheduleofStockOptionValuationAssumptionsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#ShareBasedCompensationScheduleofStockOptionValuationAssumptionsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ShareBasedCompensationScheduleofStockOptionValuationAssumptionsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-1780-73d2-9801-8058a29d24ef" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-74b2-ab31-4dffe128fdf0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-1780-73d2-9801-8058a29d24ef" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-74b2-ab31-4dffe128fdf0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_01a0eef3-1780-7695-8406-a9e13c8db3fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-74b2-ab31-4dffe128fdf0" xlink:to="loc_us-gaap_AwardTypeAxis_01a0eef3-1780-7695-8406-a9e13c8db3fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-1780-7cb8-90b0-02d7b127cde9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_01a0eef3-1780-7695-8406-a9e13c8db3fc" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-1780-7cb8-90b0-02d7b127cde9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-1780-7c59-a548-96724015931c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-1780-7cb8-90b0-02d7b127cde9" xlink:to="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-1780-7c59-a548-96724015931c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationTechniqueAxis_01a0eef3-1780-7a61-966d-0f7fe3267d05" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ValuationTechniqueAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-74b2-ab31-4dffe128fdf0" xlink:to="loc_us-gaap_ValuationTechniqueAxis_01a0eef3-1780-7a61-966d-0f7fe3267d05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationTechniqueDomain_01a0eef3-1780-7304-89f0-6d80c3cbf7d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ValuationTechniqueDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationTechniqueAxis_01a0eef3-1780-7a61-966d-0f7fe3267d05" xlink:to="loc_us-gaap_ValuationTechniqueDomain_01a0eef3-1780-7304-89f0-6d80c3cbf7d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BlackScholesMertonModelMember_01a0eef3-1780-7bd7-b81d-a15b03f1492a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BlackScholesMertonModelMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ValuationTechniqueDomain_01a0eef3-1780-7304-89f0-6d80c3cbf7d9" xlink:to="loc_us-gaap_BlackScholesMertonModelMember_01a0eef3-1780-7bd7-b81d-a15b03f1492a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_01a0eef3-1780-7227-81c2-95e2cc6072ec" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-74b2-ab31-4dffe128fdf0" xlink:to="loc_srt_RangeAxis_01a0eef3-1780-7227-81c2-95e2cc6072ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_01a0eef3-1780-7057-9d69-41a14e27d9dc" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_01a0eef3-1780-7227-81c2-95e2cc6072ec" xlink:to="loc_srt_RangeMember_01a0eef3-1780-7057-9d69-41a14e27d9dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_01a0eef3-1780-7313-a2b6-f80c7dba68a5" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-1780-7057-9d69-41a14e27d9dc" xlink:to="loc_srt_MinimumMember_01a0eef3-1780-7313-a2b6-f80c7dba68a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_01a0eef3-1780-7e7c-a9b8-798069de79e1" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_01a0eef3-1780-7057-9d69-41a14e27d9dc" xlink:to="loc_srt_MaximumMember_01a0eef3-1780-7e7c-a9b8-798069de79e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-74b2-ab31-4dffe128fdf0" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_01a0eef3-1780-78db-a90b-e402a041ced6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_01a0eef3-1780-78db-a90b-e402a041ced6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_01a0eef3-1780-7f2a-ad98-705fac6a83af" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_01a0eef3-1780-7f2a-ad98-705fac6a83af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_01a0eef3-1780-7431-97e2-dc199f0178b9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_01a0eef3-1780-7431-97e2-dc199f0178b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_01a0eef3-1780-7125-bf44-5d99350fbb9a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_01a0eef3-1780-7125-bf44-5d99350fbb9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_01a0eef3-1780-731b-8301-d29d840969f2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_01a0eef3-1780-731b-8301-d29d840969f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_01a0eef3-1780-77e1-91ed-259e6e1b2926" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_01a0eef3-1780-77e1-91ed-259e6e1b2926" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_01a0eef3-1780-7fbf-8373-130f5b5bda31" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_01a0eef3-1780-7fbf-8373-130f5b5bda31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_01a0eef3-1780-7e6a-a278-bf5ace069484" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_01a0eef3-1780-7e6a-a278-bf5ace069484" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharePrice_01a0eef3-1780-763f-b8bf-ee58ae25d587" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SharePrice"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-79d0-ab7f-0f7ebd06114d" xlink:to="loc_us-gaap_SharePrice_01a0eef3-1780-763f-b8bf-ee58ae25d587" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ShareBasedCompensationScheduleofStockOptionActivityDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#ShareBasedCompensationScheduleofStockOptionActivityDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ShareBasedCompensationScheduleofStockOptionActivityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-1780-7437-b6d4-e067f4bcff9c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-7c71-b976-2184af7d3be0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_01a0eef3-1780-7437-b6d4-e067f4bcff9c" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-7c71-b976-2184af7d3be0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_01a0eef3-1780-7aa7-b7ae-d49c3970cf82" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-7c71-b976-2184af7d3be0" xlink:to="loc_us-gaap_AwardTypeAxis_01a0eef3-1780-7aa7-b7ae-d49c3970cf82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-1780-793b-bb07-c99f6a4f67ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_01a0eef3-1780-7aa7-b7ae-d49c3970cf82" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-1780-793b-bb07-c99f6a4f67ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-1780-7f9a-a470-c69f3bf531b5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_01a0eef3-1780-793b-bb07-c99f6a4f67ff" xlink:to="loc_us-gaap_EmployeeStockOptionMember_01a0eef3-1780-7f9a-a470-c69f3bf531b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_01a0eef3-1780-7c71-b976-2184af7d3be0" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_01a0eef3-1780-7e61-ac72-c454b0d9ce39" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_01a0eef3-1780-7e61-ac72-c454b0d9ce39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_01a0eef3-1780-789b-804a-f449b4e2982e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_01a0eef3-1780-7e61-ac72-c454b0d9ce39" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_01a0eef3-1780-789b-804a-f449b4e2982e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_01a0eef3-1780-7b46-aa29-d861b2bfa852" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_01a0eef3-1780-7e61-ac72-c454b0d9ce39" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_01a0eef3-1780-7b46-aa29-d861b2bfa852" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_01a0eef3-1780-7022-b557-6480589be367" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_01a0eef3-1780-7e61-ac72-c454b0d9ce39" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_01a0eef3-1780-7022-b557-6480589be367" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisedForfeituresAndExpirationsInPeriod_01a0eef3-1780-7891-adf2-e73a8efa3fb0" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisedForfeituresAndExpirationsInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_01a0eef3-1780-7e61-ac72-c454b0d9ce39" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisedForfeituresAndExpirationsInPeriod_01a0eef3-1780-7891-adf2-e73a8efa3fb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_01a0eef3-1780-771f-8aeb-1a5ae62a60e0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_01a0eef3-1780-7e61-ac72-c454b0d9ce39" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_01a0eef3-1780-771f-8aeb-1a5ae62a60e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_01a0eef3-1780-7724-ad42-b438ae95a1f1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_01a0eef3-1780-7724-ad42-b438ae95a1f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_01a0eef3-1780-7178-b014-789603150944" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_01a0eef3-1780-7178-b014-789603150944" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_01a0eef3-1780-70d0-9951-b546d8422f67" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_01a0eef3-1780-70d0-9951-b546d8422f67" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_01a0eef3-1780-7c17-84d3-34b85e99f7d2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_01a0eef3-1780-70d0-9951-b546d8422f67" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_01a0eef3-1780-7c17-84d3-34b85e99f7d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_01a0eef3-1780-7edb-add3-1fea372a2e7a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_01a0eef3-1780-70d0-9951-b546d8422f67" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_01a0eef3-1780-7edb-add3-1fea372a2e7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_01a0eef3-1780-74c0-b088-49fcdfe1755e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_01a0eef3-1780-70d0-9951-b546d8422f67" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_01a0eef3-1780-74c0-b088-49fcdfe1755e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisedForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_01a0eef3-1780-7778-a210-4f2ff176d0af" xlink:href="aqst-20260930.xsd#aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisedForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_01a0eef3-1780-70d0-9951-b546d8422f67" xlink:to="loc_aqst_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisedForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_01a0eef3-1780-7778-a210-4f2ff176d0af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_01a0eef3-1780-73d6-8754-47a6c9ac6ef1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_01a0eef3-1780-70d0-9951-b546d8422f67" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_01a0eef3-1780-73d6-8754-47a6c9ac6ef1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_01a0eef3-1780-70db-b330-3e1646a573c0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_01a0eef3-1780-70db-b330-3e1646a573c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_01a0eef3-1780-7976-b4b4-1eea14cf1fc3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_01a0eef3-1780-7bb3-93b1-9bb634af4757" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice_01a0eef3-1780-7976-b4b4-1eea14cf1fc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/IncomeTaxesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#IncomeTaxesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/IncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_01a0eef3-1780-7dba-a044-64c7adc74bc2" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_01a0eef3-1780-7ef4-b6fc-dfb3493daddf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_01a0eef3-1780-7dba-a044-64c7adc74bc2" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_01a0eef3-1780-7ef4-b6fc-dfb3493daddf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_01a0eef3-1780-7640-a5fd-137ce8525648" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_01a0eef3-1780-7dba-a044-64c7adc74bc2" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_01a0eef3-1780-7640-a5fd-137ce8525648" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a0eef3-1780-76db-8f47-d5868e76af5a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_01a0eef3-1780-7dba-a044-64c7adc74bc2" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_01a0eef3-1780-76db-8f47-d5868e76af5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/ContingenciesDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#ContingenciesDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/ContingenciesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_01a0eef3-1780-7c93-82a3-8fe53285d567" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesTable_01a0eef3-1780-72e1-876f-af62b1e2760d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingenciesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_01a0eef3-1780-7c93-82a3-8fe53285d567" xlink:to="loc_us-gaap_LossContingenciesTable_01a0eef3-1780-72e1-876f-af62b1e2760d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseAxis_01a0eef3-1780-7b1e-a68b-1f86bbd3bc23" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_LitigationCaseAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_01a0eef3-1780-72e1-876f-af62b1e2760d" xlink:to="loc_srt_LitigationCaseAxis_01a0eef3-1780-7b1e-a68b-1f86bbd3bc23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain_01a0eef3-1780-7559-927d-c52182cf634c" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_LitigationCaseTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_01a0eef3-1780-7b1e-a68b-1f86bbd3bc23" xlink:to="loc_srt_LitigationCaseTypeDomain_01a0eef3-1780-7559-927d-c52182cf634c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SuboxoneProduceLiabilityLitigationMember_01a0eef3-1780-77bb-bbd2-98091e677bde" xlink:href="aqst-20260930.xsd#aqst_SuboxoneProduceLiabilityLitigationMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_01a0eef3-1780-7559-927d-c52182cf634c" xlink:to="loc_aqst_SuboxoneProduceLiabilityLitigationMember_01a0eef3-1780-77bb-bbd2-98091e677bde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_01a0eef3-1780-7b24-8c8f-0f0309cfd78d" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_StatementGeographicalAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_01a0eef3-1780-72e1-876f-af62b1e2760d" xlink:to="loc_srt_StatementGeographicalAxis_01a0eef3-1780-7b24-8c8f-0f0309cfd78d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_01a0eef3-1780-7edc-bcbe-12b00f3731fd" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_SegmentGeographicalDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_01a0eef3-1780-7b24-8c8f-0f0309cfd78d" xlink:to="loc_srt_SegmentGeographicalDomain_01a0eef3-1780-7edc-bcbe-12b00f3731fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_stpr_CA-BC_01a0eef3-1780-7ba9-9b67-ab9c1417fc97" xlink:href="https://xbrl.sec.gov/stpr/2026/stpr-2026.xsd#stpr_CA-BC"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_01a0eef3-1780-7edc-bcbe-12b00f3731fd" xlink:to="loc_stpr_CA-BC_01a0eef3-1780-7ba9-9b67-ab9c1417fc97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingenciesLineItems_01a0eef3-1780-7b36-af2c-0beeb6cb4560" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingenciesLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesTable_01a0eef3-1780-72e1-876f-af62b1e2760d" xlink:to="loc_us-gaap_LossContingenciesLineItems_01a0eef3-1780-7b36-af2c-0beeb6cb4560" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_01a0eef3-1780-7b0a-ae72-ea63c5060432" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LossContingencyPendingClaimsNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LossContingenciesLineItems_01a0eef3-1780-7b36-af2c-0beeb6cb4560" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_01a0eef3-1780-7b0a-ae72-ea63c5060432" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://aquestive.com/role/SubsequentEventsDetails" xlink:type="simple" xlink:href="aqst-20260930.xsd#SubsequentEventsDetails"/>
  <link:presentationLink xlink:role="http://aquestive.com/role/SubsequentEventsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_01a17822-0959-7399-83dc-791aeee40336" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_01a17822-363a-7376-8c81-7de069ad6e16" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_01a17822-0959-7399-83dc-791aeee40336" xlink:to="loc_us-gaap_SubsequentEventTable_01a17822-363a-7376-8c81-7de069ad6e16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_01a18588-3b2c-700f-82d2-a588f2c71685" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_01a17822-363a-7376-8c81-7de069ad6e16" xlink:to="loc_srt_CounterpartyNameAxis_01a18588-3b2c-700f-82d2-a588f2c71685" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_01a18588-3b2c-7b97-83cf-0a67cf9de885" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_01a18588-3b2c-700f-82d2-a588f2c71685" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_01a18588-3b2c-7b97-83cf-0a67cf9de885" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_EtonPharmaceuticalsInc.Member_01a18588-3b2c-7340-869f-6d096653690d" xlink:href="aqst-20260930.xsd#aqst_EtonPharmaceuticalsInc.Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_01a18588-3b2c-7b97-83cf-0a67cf9de885" xlink:to="loc_aqst_EtonPharmaceuticalsInc.Member_01a18588-3b2c-7340-869f-6d096653690d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_01a18588-3b2c-7f24-9fc3-470c720d0e6f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_01a17822-363a-7376-8c81-7de069ad6e16" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_01a18588-3b2c-7f24-9fc3-470c720d0e6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_01a18588-3b2c-7cf5-a533-3168d34b21d6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_01a18588-3b2c-7f24-9fc3-470c720d0e6f" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_01a18588-3b2c-7cf5-a533-3168d34b21d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_01a18588-3b2c-7987-a12f-e572a679ecbf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_01a18588-3b2c-7cf5-a533-3168d34b21d6" xlink:to="loc_us-gaap_SubsequentEventMember_01a18588-3b2c-7987-a12f-e572a679ecbf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_01a18588-3b2c-7e39-b955-1b841900e2a7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_01a17822-363a-7376-8c81-7de069ad6e16" xlink:to="loc_us-gaap_TypeOfArrangementAxis_01a18588-3b2c-7e39-b955-1b841900e2a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a18588-3b2c-7677-a0a7-26da7388e25c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_01a18588-3b2c-7e39-b955-1b841900e2a7" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a18588-3b2c-7677-a0a7-26da7388e25c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicensingAndSupplyAgreementMember_01a18588-3b2c-7c51-a136-fcdb0d425fb8" xlink:href="aqst-20260930.xsd#aqst_LicensingAndSupplyAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_01a18588-3b2c-7677-a0a7-26da7388e25c" xlink:to="loc_aqst_LicensingAndSupplyAgreementMember_01a18588-3b2c-7c51-a136-fcdb0d425fb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CollaborativeArrangementMilestoneRequirementsAxis_01a18588-3b2c-7040-8606-9746ffde4556" xlink:href="aqst-20260930.xsd#aqst_CollaborativeArrangementMilestoneRequirementsAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_01a17822-363a-7376-8c81-7de069ad6e16" xlink:to="loc_aqst_CollaborativeArrangementMilestoneRequirementsAxis_01a18588-3b2c-7040-8606-9746ffde4556" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_CollaborativeArrangementMilestoneRequirementsDomain_01a18588-3b2c-73d3-9556-6d1bc63a26d1" xlink:href="aqst-20260930.xsd#aqst_CollaborativeArrangementMilestoneRequirementsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_CollaborativeArrangementMilestoneRequirementsAxis_01a18588-3b2c-7040-8606-9746ffde4556" xlink:to="loc_aqst_CollaborativeArrangementMilestoneRequirementsDomain_01a18588-3b2c-73d3-9556-6d1bc63a26d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_AggregateSpecifiedMilestonesMember_01a19ca2-d1f9-7929-8ee5-d1b0efb5152c" xlink:href="aqst-20260930.xsd#aqst_AggregateSpecifiedMilestonesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_CollaborativeArrangementMilestoneRequirementsDomain_01a18588-3b2c-73d3-9556-6d1bc63a26d1" xlink:to="loc_aqst_AggregateSpecifiedMilestonesMember_01a19ca2-d1f9-7929-8ee5-d1b0efb5152c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_FirstCommercialSaleUnitedStatesMember_01a19c9e-5efe-707e-a39c-92de005475ea" xlink:href="aqst-20260930.xsd#aqst_FirstCommercialSaleUnitedStatesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_CollaborativeArrangementMilestoneRequirementsDomain_01a18588-3b2c-73d3-9556-6d1bc63a26d1" xlink:to="loc_aqst_FirstCommercialSaleUnitedStatesMember_01a19c9e-5efe-707e-a39c-92de005475ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_FirstCommercialSaleUnitedStatesWithoutFDAApprovalAgesTwoToFiveMember_01a18588-3b2c-77f9-ba62-2039a4a0f8a3" xlink:href="aqst-20260930.xsd#aqst_FirstCommercialSaleUnitedStatesWithoutFDAApprovalAgesTwoToFiveMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_CollaborativeArrangementMilestoneRequirementsDomain_01a18588-3b2c-73d3-9556-6d1bc63a26d1" xlink:to="loc_aqst_FirstCommercialSaleUnitedStatesWithoutFDAApprovalAgesTwoToFiveMember_01a18588-3b2c-77f9-ba62-2039a4a0f8a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_FirstCommercialSaleUnitedStatesUponFDAApprovalAgesSixToElevenMember_01a18588-3b2c-7bd1-9904-6c67281ff6e4" xlink:href="aqst-20260930.xsd#aqst_FirstCommercialSaleUnitedStatesUponFDAApprovalAgesSixToElevenMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_CollaborativeArrangementMilestoneRequirementsDomain_01a18588-3b2c-73d3-9556-6d1bc63a26d1" xlink:to="loc_aqst_FirstCommercialSaleUnitedStatesUponFDAApprovalAgesSixToElevenMember_01a18588-3b2c-7bd1-9904-6c67281ff6e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_FirstCommercialSaleUnitedStatesCommercialNetSalesMilestonesMember_01a18588-3b2c-740c-9a6a-50a6859055f0" xlink:href="aqst-20260930.xsd#aqst_FirstCommercialSaleUnitedStatesCommercialNetSalesMilestonesMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_aqst_CollaborativeArrangementMilestoneRequirementsDomain_01a18588-3b2c-73d3-9556-6d1bc63a26d1" xlink:to="loc_aqst_FirstCommercialSaleUnitedStatesCommercialNetSalesMilestonesMember_01a18588-3b2c-740c-9a6a-50a6859055f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_01a18588-3b2c-7e33-8d4f-9d5006be7846" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_01a17822-363a-7376-8c81-7de069ad6e16" xlink:to="loc_us-gaap_SubsequentEventLineItems_01a18588-3b2c-7e33-8d4f-9d5006be7846" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicenseAndSupplyArrangementLicenseFeePaymentReceived_01a18588-3b2c-7183-b5a3-2db932db02dc" xlink:href="aqst-20260930.xsd#aqst_LicenseAndSupplyArrangementLicenseFeePaymentReceived"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_01a18588-3b2c-7e33-8d4f-9d5006be7846" xlink:to="loc_aqst_LicenseAndSupplyArrangementLicenseFeePaymentReceived_01a18588-3b2c-7183-b5a3-2db932db02dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_LicensingAndSupplyAgreementMilestonePaymentsReceivable_01a18588-3b2c-7150-9c5f-54edb234a58f" xlink:href="aqst-20260930.xsd#aqst_LicensingAndSupplyAgreementMilestonePaymentsReceivable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_01a18588-3b2c-7e33-8d4f-9d5006be7846" xlink:to="loc_aqst_LicensingAndSupplyAgreementMilestonePaymentsReceivable_01a18588-3b2c-7150-9c5f-54edb234a58f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SupplyAgreementInitialTerm_01a18635-721e-7a94-bef4-7b6e64d45f53" xlink:href="aqst-20260930.xsd#aqst_SupplyAgreementInitialTerm"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_01a18588-3b2c-7e33-8d4f-9d5006be7846" xlink:to="loc_aqst_SupplyAgreementInitialTerm_01a18635-721e-7a94-bef4-7b6e64d45f53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SupplyAgreementExtensionTerm_01a18635-721e-7a14-aacc-d3456fa76bf2" xlink:href="aqst-20260930.xsd#aqst_SupplyAgreementExtensionTerm"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_01a18588-3b2c-7e33-8d4f-9d5006be7846" xlink:to="loc_aqst_SupplyAgreementExtensionTerm_01a18635-721e-7a14-aacc-d3456fa76bf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_SupplyAgreementTerminationNoticePeriod_01a18635-721e-7cbc-b168-b6997a56caf6" xlink:href="aqst-20260930.xsd#aqst_SupplyAgreementTerminationNoticePeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_01a18588-3b2c-7e33-8d4f-9d5006be7846" xlink:to="loc_aqst_SupplyAgreementTerminationNoticePeriod_01a18635-721e-7cbc-b168-b6997a56caf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/AwardTimingDisclosure" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#AwardTimingDisclosure"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/AwardTimingDisclosure" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgDiscLineItems" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardTmgDiscLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgMnpiDiscTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardTmgMnpiDiscTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgMnpiDiscTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgMethodTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardTmgMethodTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgMethodTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgPredtrmndFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardTmgPredtrmndFlag"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgPredtrmndFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgMnpiCnsdrdFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardTmgMnpiCnsdrdFlag"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgMnpiCnsdrdFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardTmgHowMnpiCnsdrdTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardTmgHowMnpiCnsdrdTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardTmgHowMnpiCnsdrdTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MnpiDiscTimedForCompValFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_MnpiDiscTimedForCompValFlag"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_MnpiDiscTimedForCompValFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardsCloseToMnpiDiscTableTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardsCloseToMnpiDiscTableTextBlock"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardsCloseToMnpiDiscTableTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardsCloseToMnpiDiscTable"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardsCloseToMnpiDiscTable" xlink:to="loc_us-gaap_AwardTypeAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_us-gaap_EmployeeStockOptionMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockAppreciationRightsSARSMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockAppreciationRightsSARSMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:to="loc_us-gaap_StockAppreciationRightsSARSMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardsCloseToMnpiDiscIndName" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardsCloseToMnpiDiscIndName"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardsCloseToMnpiDiscIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardUndrlygSecuritiesAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardUndrlygSecuritiesAmt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardUndrlygSecuritiesAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardExrcPrice" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardExrcPrice"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardExrcPrice" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AwardGrantDateFairValue" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AwardGrantDateFairValue"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_AwardGrantDateFairValue" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_UndrlygSecurityMktPriceChngPct" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_UndrlygSecurityMktPriceChngPct"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AwardTmgDiscLineItems" xlink:to="loc_ecd_UndrlygSecurityMktPriceChngPct" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/ErrCompDisclosure" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ErrCompDisclosure"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/ErrCompDisclosure" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_RecoveryOfErrCompDisclosureLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ErrCompRecoveryTable" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ErrCompRecoveryTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ErrCompRecoveryTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RestatementDateAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_RestatementDateAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_ErrCompRecoveryTable" xlink:to="loc_ecd_RestatementDateAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_ErrCompRecoveryTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonNeosMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NonNeosMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllIndividualsMember" xlink:to="loc_ecd_NonNeosMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RestatementDeterminationDate" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_RestatementDeterminationDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_RestatementDeterminationDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtErrCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AggtErrCompAmt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_AggtErrCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ErrCompAnalysisTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ErrCompAnalysisTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ErrCompAnalysisTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_StkPrcOrTsrEstimationMethodTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_StkPrcOrTsrEstimationMethodTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_StkPrcOrTsrEstimationMethodTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OutstandingAggtErrCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_OutstandingAggtErrCompAmt"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_OutstandingAggtErrCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtErrCompNotYetDeterminedTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AggtErrCompNotYetDeterminedTextBlock"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_AggtErrCompNotYetDeterminedTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryIndName" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ForgoneRecoveryIndName"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryDueToExpenseOfEnforcementAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ForgoneRecoveryDueToExpenseOfEnforcementAmt"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryDueToExpenseOfEnforcementAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryDueToViolationOfHomeCountryLawAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ForgoneRecoveryDueToViolationOfHomeCountryLawAmt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryDueToViolationOfHomeCountryLawAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryDueToDisqualificationOfTaxBenefitsAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ForgoneRecoveryDueToDisqualificationOfTaxBenefitsAmt"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryDueToDisqualificationOfTaxBenefitsAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ForgoneRecoveryExplanationOfImpracticabilityTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ForgoneRecoveryExplanationOfImpracticabilityTextBlock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_ForgoneRecoveryExplanationOfImpracticabilityTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OutstandingRecoveryIndName" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_OutstandingRecoveryIndName"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_OutstandingRecoveryIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OutstandingRecoveryCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_OutstandingRecoveryCompAmt"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_OutstandingRecoveryCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_RestatementDoesNotRequireRecoveryTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_RestatementDoesNotRequireRecoveryTextBlock"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_RecoveryOfErrCompDisclosureLineItems" xlink:to="loc_ecd_RestatementDoesNotRequireRecoveryTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/PvpDisclosure" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#PvpDisclosure"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/PvpDisclosure" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PayVsPerformanceDisclosureLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PvpTable" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PvpTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PvpTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ExecutiveCategoryAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ExecutiveCategoryAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_ExecutiveCategoryAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllExecutiveCategoriesMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AllExecutiveCategoriesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_ExecutiveCategoryAxis" xlink:to="loc_ecd_AllExecutiveCategoriesMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PeoMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllExecutiveCategoriesMember" xlink:to="loc_ecd_PeoMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonPeoNeoMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NonPeoNeoMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllExecutiveCategoriesMember" xlink:to="loc_ecd_NonPeoNeoMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToCompAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AdjToCompAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_AdjToCompAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllAdjToCompMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AllAdjToCompMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AdjToCompAxis" xlink:to="loc_ecd_AllAdjToCompMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtChngPnsnValInSummryCompstnTblForAplblYrMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AggtChngPnsnValInSummryCompstnTblForAplblYrMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllAdjToCompMember" xlink:to="loc_ecd_AggtChngPnsnValInSummryCompstnTblForAplblYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AggtPnsnAdjsSvcCstMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllAdjToCompMember" xlink:to="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PnsnAdjsSvcCstMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PnsnAdjsSvcCstMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:to="loc_ecd_PnsnAdjsSvcCstMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PnsnAdjsPrrSvcCstMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PnsnAdjsPrrSvcCstMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AggtPnsnAdjsSvcCstMember" xlink:to="loc_ecd_PnsnAdjsPrrSvcCstMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsAdjsMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_EqtyAwrdsAdjsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllAdjToCompMember" xlink:to="loc_ecd_EqtyAwrdsAdjsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsInSummryCompstnTblForAplblYrMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_EqtyAwrdsInSummryCompstnTblForAplblYrMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsMember" xlink:to="loc_ecd_EqtyAwrdsInSummryCompstnTblForAplblYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsMember" xlink:to="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_YrEndFrValOfEqtyAwrdsGrntdInCvrdYrOutsdngAndUnvstdMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_ChngInFrValOfOutsdngAndUnvstdEqtyAwrdsGrntdInPrrYrsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_VstngDtFrValOfEqtyAwrdsGrntdAndVstdInCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_ChngInFrValAsOfVstngDtOfPrrYrEqtyAwrdsVstdInCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_FrValAsOfPrrYrEndOfEqtyAwrdsGrntdInPrrYrsFldVstngCondsDrngCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_DvddsOrOthrErngsPdOnEqtyAwrdsNtOthrwsRflctdInTtlCompForCvrdYrMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_DvddsOrOthrErngsPdOnEqtyAwrdsNtOthrwsRflctdInTtlCompForCvrdYrMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_EqtyAwrdsAdjsExclgValRprtdInSummryCompstnTblMember" xlink:to="loc_ecd_DvddsOrOthrErngsPdOnEqtyAwrdsNtOthrwsRflctdInTtlCompForCvrdYrMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MeasureAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_MeasureAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PvpTable" xlink:to="loc_ecd_MeasureAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PvpTableTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PvpTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PvpTableTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CoSelectedMeasureName" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_CoSelectedMeasureName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CoSelectedMeasureName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NamedExecutiveOfficersFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NamedExecutiveOfficersFnTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NamedExecutiveOfficersFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeerGroupIssuersFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PeerGroupIssuersFnTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeerGroupIssuersFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_ChangedPeerGroupFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_ChangedPeerGroupFnTextBlock"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_ChangedPeerGroupFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoTotalCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PeoTotalCompAmt"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeoTotalCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoActuallyPaidCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PeoActuallyPaidCompAmt"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeoActuallyPaidCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToPeoCompFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AdjToPeoCompFnTextBlock"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_AdjToPeoCompFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonPeoNeoAvgTotalCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NonPeoNeoAvgTotalCompAmt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NonPeoNeoAvgTotalCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonPeoNeoAvgCompActuallyPaidAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NonPeoNeoAvgCompActuallyPaidAmt"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NonPeoNeoAvgCompActuallyPaidAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToNonPeoNeoCompFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AdjToNonPeoNeoCompFnTextBlock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_AdjToNonPeoNeoCompFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EquityValuationAssumptionDifferenceFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_EquityValuationAssumptionDifferenceFnTextBlock"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_EquityValuationAssumptionDifferenceFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsTotalShareholderRtnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_CompActuallyPaidVsTotalShareholderRtnTextBlock"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsTotalShareholderRtnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsNetIncomeTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_CompActuallyPaidVsNetIncomeTextBlock"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsNetIncomeTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsCoSelectedMeasureTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_CompActuallyPaidVsCoSelectedMeasureTextBlock"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsCoSelectedMeasureTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TotalShareholderRtnVsPeerGroupTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TotalShareholderRtnVsPeerGroupTextBlock"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_TotalShareholderRtnVsPeerGroupTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CompActuallyPaidVsOtherMeasureTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_CompActuallyPaidVsOtherMeasureTextBlock"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CompActuallyPaidVsOtherMeasureTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TabularListTableTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TabularListTableTextBlock"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_TabularListTableTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TotalShareholderRtnAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TotalShareholderRtnAmt"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_TotalShareholderRtnAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeerGroupTotalShareholderRtnAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PeerGroupTotalShareholderRtnAmt"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeerGroupTotalShareholderRtnAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_CoSelectedMeasureAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_CoSelectedMeasureAmt"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_CoSelectedMeasureAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_OtherPerfMeasureAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_OtherPerfMeasureAmt"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_OtherPerfMeasureAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AdjToCompAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AdjToCompAmt"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_AdjToCompAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PeoName" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PeoName"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PeoName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MeasureName" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_MeasureName"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_MeasureName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonGaapMeasureDescriptionTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NonGaapMeasureDescriptionTextBlock"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_NonGaapMeasureDescriptionTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_Additional402vDisclosureTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_Additional402vDisclosureTextBlock"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_Additional402vDisclosureTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_PnsnBnftsAdjFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_PnsnBnftsAdjFnTextBlock"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_PnsnBnftsAdjFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_EqtyAwrdsAdjFnTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_EqtyAwrdsAdjFnTextBlock"/>
    <link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_PayVsPerformanceDisclosureLineItems" xlink:to="loc_ecd_EqtyAwrdsAdjFnTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#InsiderTradingArrangements"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTradingArrLineItems" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_InsiderTradingArrLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TradingArrByIndTable" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TradingArrByIndTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TradingArrByIndTable" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TradingArrAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TradingArrAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_TradingArrByIndTable" xlink:to="loc_ecd_TradingArrAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllTradingArrangementsMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AllTradingArrangementsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_TradingArrAxis" xlink:to="loc_ecd_AllTradingArrangementsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_IndividualAxis" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_IndividualAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_TradingArrByIndTable" xlink:to="loc_ecd_IndividualAxis" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_AllIndividualsMember" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_AllIndividualsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_IndividualAxis" xlink:to="loc_ecd_AllIndividualsMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_PeterBoydMember" xlink:href="aqst-20260930.xsd#aqst_PeterBoydMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllIndividualsMember" xlink:to="loc_aqst_PeterBoydMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/label"/>
    <link:loc xlink:type="locator" xlink:label="loc_aqst_JulieKropMember" xlink:href="aqst-20260930.xsd#aqst_JulieKropMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_AllIndividualsMember" xlink:to="loc_aqst_JulieKropMember" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/label"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_MtrlTermsOfTrdArrTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_MtrlTermsOfTrdArrTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_MtrlTermsOfTrdArrTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrIndName" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TrdArrIndName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrIndName" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrIndTitle" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TrdArrIndTitle"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrIndTitle" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_Rule10b51ArrAdoptedFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_Rule10b51ArrAdoptedFlag"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_Rule10b51ArrAdoptedFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonRule10b51ArrAdoptedFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NonRule10b51ArrAdoptedFlag"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_NonRule10b51ArrAdoptedFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrAdoptionDate" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TrdArrAdoptionDate"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrAdoptionDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_Rule10b51ArrTrmntdFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_Rule10b51ArrTrmntdFlag"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_Rule10b51ArrTrmntdFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_NonRule10b51ArrTrmntdFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_NonRule10b51ArrTrmntdFlag"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_NonRule10b51ArrTrmntdFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrTerminationDate" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TrdArrTerminationDate"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrTerminationDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrExpirationDate" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TrdArrExpirationDate"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrExpirationDate" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrDuration" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TrdArrDuration"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrDuration" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_TrdArrSecuritiesAggAvailAmt" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_TrdArrSecuritiesAggAvailAmt"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingArrLineItems" xlink:to="loc_ecd_TrdArrSecuritiesAggAvailAmt" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://xbrl.sec.gov/ecd/role/InsiderTradingPoliciesProc" xlink:type="simple" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#InsiderTradingPoliciesProc"/>
  <link:presentationLink xlink:role="http://xbrl.sec.gov/ecd/role/InsiderTradingPoliciesProc" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTradingPoliciesProcLineItems" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_InsiderTradingPoliciesProcLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTrdPoliciesProcAdoptedFlag" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_InsiderTrdPoliciesProcAdoptedFlag"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingPoliciesProcLineItems" xlink:to="loc_ecd_InsiderTrdPoliciesProcAdoptedFlag" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_ecd_InsiderTrdPoliciesProcNotAdoptedTextBlock" xlink:href="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd#ecd_InsiderTrdPoliciesProcNotAdoptedTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_ecd_InsiderTradingPoliciesProcLineItems" xlink:to="loc_ecd_InsiderTrdPoliciesProcNotAdoptedTextBlock" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
