CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY (unaudited) - USD ($) $ in Thousands |
Total |
Ordinary Shares |
Additional Paid-In Capital |
Accumulated Other Comprehensive Loss |
Accumulated Deficit |
Treasury Stock |
| BALANCE at Dec. 31, 2024 |
$ 1,464,977
|
$ 1,767
|
$ 2,860,890
|
$ (1,967)
|
$ (976,458)
|
$ (419,255)
|
| BALANCE (in shares) at Dec. 31, 2024 |
|
176,670,785
|
|
|
|
|
| Treasury Stock, Common, Shares at Dec. 31, 2024 |
|
|
|
|
|
(14,493,791)
|
| Issuance of ordinary shares under employee stock plans |
29,528
|
$ 35
|
29,493
|
|
|
|
| Issuance of ordinary shares under employee stock plans (in shares) |
|
3,510,611
|
|
|
|
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards |
(28,781)
|
|
|
|
|
$ (28,781)
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards (in shares) |
|
|
|
|
|
(834,590)
|
| Share-based compensation |
22,883
|
|
22,883
|
|
|
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
512
|
|
|
512
|
|
|
| Net (loss) income |
22,464
|
|
|
|
22,464
|
|
| BALANCE at Mar. 31, 2025 |
1,511,583
|
$ 1,802
|
2,913,266
|
(1,455)
|
(953,994)
|
$ (448,036)
|
| BALANCE (in shares) at Mar. 31, 2025 |
|
180,181,396
|
|
|
|
|
| Treasury Stock, Common, Shares at Mar. 31, 2025 |
|
|
|
|
|
(15,328,381)
|
| BALANCE at Dec. 31, 2024 |
1,464,977
|
$ 1,767
|
2,860,890
|
(1,967)
|
(976,458)
|
$ (419,255)
|
| BALANCE (in shares) at Dec. 31, 2024 |
|
176,670,785
|
|
|
|
|
| Treasury Stock, Common, Shares at Dec. 31, 2024 |
|
|
|
|
|
(14,493,791)
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
908
|
|
|
|
|
|
| Net (loss) income |
192,323
|
|
|
|
|
|
| BALANCE at Sep. 30, 2025 |
1,733,432
|
$ 1,805
|
2,966,842
|
(1,059)
|
(784,135)
|
$ (450,021)
|
| BALANCE (in shares) at Sep. 30, 2025 |
|
180,499,470
|
|
|
|
|
| Treasury Stock, Common, Shares at Sep. 30, 2025 |
|
|
|
|
|
(15,395,579)
|
| BALANCE at Mar. 31, 2025 |
1,511,583
|
$ 1,802
|
2,913,266
|
(1,455)
|
(953,994)
|
$ (448,036)
|
| BALANCE (in shares) at Mar. 31, 2025 |
|
180,181,396
|
|
|
|
|
| Treasury Stock, Common, Shares at Mar. 31, 2025 |
|
|
|
|
|
(15,328,381)
|
| Issuance of ordinary shares under employee stock plans |
2,083
|
$ 3
|
2,080
|
|
|
|
| Issuance of ordinary shares under employee stock plans (in shares) |
|
258,354
|
|
|
|
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards |
(1,678)
|
|
|
|
|
$ (1,678)
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards (in shares) |
|
|
|
|
|
(56,457)
|
| Share-based compensation |
25,443
|
|
25,443
|
|
|
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
55
|
|
|
55
|
|
|
| Net (loss) income |
87,098
|
|
|
|
87,098
|
|
| BALANCE at Jun. 30, 2025 |
1,624,584
|
$ 1,805
|
2,940,789
|
(1,400)
|
(866,896)
|
$ (449,714)
|
| BALANCE (in shares) at Jun. 30, 2025 |
|
180,439,750
|
|
|
|
|
| Treasury Stock, Common, Shares at Jun. 30, 2025 |
|
|
|
|
|
(15,384,838)
|
| Issuance of ordinary shares under employee stock plans |
622
|
|
622
|
|
|
|
| Issuance of ordinary shares under employee stock plans (in shares) |
|
59,720
|
|
|
|
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards |
(307)
|
|
|
|
|
$ (307)
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards (in shares) |
|
|
|
|
|
(10,741)
|
| Share-based compensation |
25,431
|
|
25,431
|
|
|
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
341
|
|
|
341
|
|
|
| Net (loss) income |
82,761
|
|
|
|
82,761
|
|
| BALANCE at Sep. 30, 2025 |
1,733,432
|
$ 1,805
|
2,966,842
|
(1,059)
|
(784,135)
|
$ (450,021)
|
| BALANCE (in shares) at Sep. 30, 2025 |
|
180,499,470
|
|
|
|
|
| Treasury Stock, Common, Shares at Sep. 30, 2025 |
|
|
|
|
|
(15,395,579)
|
| BALANCE at Dec. 31, 2025 |
$ 1,819,295
|
$ 1,810
|
3,004,666
|
(2,100)
|
(734,794)
|
$ (450,287)
|
| BALANCE (in shares) at Dec. 31, 2025 |
|
181,011,166
|
|
|
|
|
| Treasury Stock, Common, Shares at Dec. 31, 2025 |
15,404,138
|
|
|
|
|
(15,404,138)
|
| Issuance of ordinary shares under employee stock plans |
$ 15,714
|
$ 26
|
15,688
|
|
|
|
| Issuance of ordinary shares under employee stock plans (in shares) |
|
2,581,702
|
|
|
|
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards |
(23,442)
|
|
|
|
|
$ (23,442)
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards (in shares) |
|
|
|
|
|
(730,937)
|
| Repurchase of Alkermes' ordinary shares |
$ (27,696)
|
|
|
|
|
$ (27,696)
|
| Repurchase of Alkermes' ordinary shares (in shares) |
(1,000,000)
|
|
|
|
|
(995,494)
|
| Share-based compensation |
$ 34,948
|
|
34,948
|
|
|
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
(568)
|
|
|
(568)
|
|
|
| Foreign currency translation loss |
(240)
|
|
|
(240)
|
|
|
| Net (loss) income |
(66,480)
|
|
|
|
(66,480)
|
|
| BALANCE at Mar. 31, 2026 |
1,751,531
|
$ 1,836
|
3,055,302
|
(2,908)
|
(801,274)
|
$ (501,425)
|
| BALANCE (in shares) at Mar. 31, 2026 |
|
183,592,868
|
|
|
|
|
| Treasury Stock, Common, Shares at Mar. 31, 2026 |
|
|
|
|
|
(17,130,569)
|
| BALANCE at Dec. 31, 2025 |
$ 1,819,295
|
$ 1,810
|
3,004,666
|
(2,100)
|
(734,794)
|
$ (450,287)
|
| BALANCE (in shares) at Dec. 31, 2025 |
|
181,011,166
|
|
|
|
|
| Treasury Stock, Common, Shares at Dec. 31, 2025 |
15,404,138
|
|
|
|
|
(15,404,138)
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
$ (1,190)
|
|
|
|
|
|
| Net (loss) income |
(49,692)
|
|
|
|
|
|
| BALANCE at Sep. 30, 2026 |
$ 1,864,721
|
$ 1,852
|
3,153,839
|
(3,290)
|
(784,486)
|
$ (503,194)
|
| BALANCE (in shares) at Sep. 30, 2026 |
|
185,203,061
|
|
|
|
|
| Treasury Stock, Common, Shares at Sep. 30, 2026 |
17,173,165
|
|
|
|
|
(17,173,165)
|
| BALANCE at Mar. 31, 2026 |
$ 1,751,531
|
$ 1,836
|
3,055,302
|
(2,908)
|
(801,274)
|
$ (501,425)
|
| BALANCE (in shares) at Mar. 31, 2026 |
|
183,592,868
|
|
|
|
|
| Treasury Stock, Common, Shares at Mar. 31, 2026 |
|
|
|
|
|
(17,130,569)
|
| Issuance of ordinary shares under employee stock plans |
26,292
|
$ 11
|
26,281
|
|
|
|
| Issuance of ordinary shares under employee stock plans (in shares) |
|
1,107,850
|
|
|
|
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards |
$ (1,096)
|
|
|
|
|
$ (1,096)
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards (in shares) |
|
|
|
|
|
(28,951)
|
| Repurchase of Alkermes' ordinary shares (in shares) |
0
|
|
|
|
|
|
| Share-based compensation |
$ 31,337
|
|
31,337
|
|
|
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
(255)
|
|
|
(255)
|
|
|
| Foreign currency translation loss |
240
|
|
|
240
|
|
|
| Net (loss) income |
501
|
|
|
|
501
|
|
| BALANCE at Jun. 30, 2026 |
1,808,550
|
$ 1,847
|
3,112,920
|
(2,923)
|
(800,773)
|
$ (502,521)
|
| BALANCE (in shares) at Jun. 30, 2026 |
|
184,700,718
|
|
|
|
|
| Treasury Stock, Common, Shares at Jun. 30, 2026 |
|
|
|
|
|
(17,159,520)
|
| Issuance of ordinary shares under employee stock plans |
13,616
|
$ 5
|
13,611
|
|
|
|
| Issuance of ordinary shares under employee stock plans (in shares) |
|
502,343
|
|
|
|
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards |
$ (673)
|
|
|
|
|
$ (673)
|
| Receipt of Alkermes' ordinary shares for the exercise of stock options or to satisfy minimum tax withholding obligations related to share-based awards (in shares) |
|
|
|
|
|
(13,645)
|
| Repurchase of Alkermes' ordinary shares (in shares) |
0
|
|
|
|
|
|
| Share-based compensation |
$ 27,308
|
|
27,308
|
|
|
|
| Unrealized gain (loss) on marketable securities, net of tax benefit |
(367)
|
|
|
(367)
|
|
|
| Net (loss) income |
16,287
|
|
|
|
16,287
|
|
| BALANCE at Sep. 30, 2026 |
$ 1,864,721
|
$ 1,852
|
$ 3,153,839
|
$ (3,290)
|
$ (784,486)
|
$ (503,194)
|
| BALANCE (in shares) at Sep. 30, 2026 |
|
185,203,061
|
|
|
|
|
| Treasury Stock, Common, Shares at Sep. 30, 2026 |
17,173,165
|
|
|
|
|
(17,173,165)
|