Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2026	Dec. 31, 2025
Current assets:
Cash and cash equivalents	$ 102,870	$ 205,326
Short-term marketable securities	413,326	662,553
Accounts receivable, net	18,882	0
Inventory	26,275	0
Prepaid expenses and other current assets	30,355	32,779
Total current assets	591,708	900,658
Long-term marketable securities	491,376	98,322
Property and equipment, net	47,907	52,402
Finance lease right-of-use asset	45,784	48,531
Operating lease right-of-use asset	15,612	19,002
Intangible asset, net	34,500	0
Other non-current assets	29,148	25,939
Total assets	1,256,035	1,144,854
Current liabilities:
Accounts payable	13,700	505
Accrued expenses and other current liabilities	81,558	97,846
Total current liabilities	95,258	98,351
Operating lease liability, less current portion	19,280	27,210
Finance lease liability, less current portion	5,449	5,532
Liability related to the revenue participation right agreement	209,661	0
Total liabilities	329,648	131,093
Commitments and contingencies (Note 10)
Stockholders' equity:
Convertible preferred stock, $0.01 par value; 40,000,000 shares authorized as of September 30, 2026 and December 31, 2025; 0 shares issued and outstanding as of September 30, 2026 and December 31, 2025	0	0
Common stock, $0.01 par value; 400,000,000 shares authorized as of September 30, 2026 and December 31, 2025; 160,257,940 shares and 156,182,177 shares issued and outstanding as of September 30, 2026 and December 31, 2025, respectively	1,929	1,888
Additional paid-in capital	3,168,215	3,062,715
Accumulated other comprehensive income (loss)	(6,359)	682
Accumulated deficit	(2,237,398)	(2,051,524)
Total stockholders' equity	926,387	1,013,761
Total liabilities and stockholders’ equity	$ 1,256,035	$ 1,144,854

Royalty Funding Arrangement Liability, Noncurrent

No definition available.

Name:	dnli_RoyaltyFundingArrangementLiabilityNoncurrent
Namespace Prefix:	dnli_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).