<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:01a0694f-13a1-7052-8261-97a2428a0df2,g:4a722a2a-e045-4d75-85a2-88bd5891e6f3-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://si-bone.com/role/Cover" xlink:type="simple" xlink:href="sibn-20261102.xsd#Cover"/>
  <link:presentationLink xlink:role="http://si-bone.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_01a0694f-13a1-7660-8b61-1ee6b891e9f9" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_DocumentType_01a0694f-13a1-7660-8b61-1ee6b891e9f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_01a0694f-13a1-7b4c-ae92-f3c329c55ac2" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_DocumentPeriodEndDate_01a0694f-13a1-7b4c-ae92-f3c329c55ac2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_01a0694f-13a1-7c7c-95c2-ddc20ce00ca2" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityRegistrantName_01a0694f-13a1-7c7c-95c2-ddc20ce00ca2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_01a0694f-13a1-7784-b557-76fe46d94217" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityCentralIndexKey_01a0694f-13a1-7784-b557-76fe46d94217" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_01a0694f-13a1-7adb-86d2-9c40b583a237" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_AmendmentFlag_01a0694f-13a1-7adb-86d2-9c40b583a237" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_01a0694f-13a1-7044-acc7-ae51f4868ec4" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityIncorporationStateCountryCode_01a0694f-13a1-7044-acc7-ae51f4868ec4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_01a0694f-13a1-7d84-901f-9d8c0ef8d6e6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityFileNumber_01a0694f-13a1-7d84-901f-9d8c0ef8d6e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_01a0694f-13a1-70f3-bfb8-13eb2a7f1349" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityTaxIdentificationNumber_01a0694f-13a1-70f3-bfb8-13eb2a7f1349" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_01a0694f-13a1-7abf-87f8-c5e02d13c686" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityAddressAddressLine1_01a0694f-13a1-7abf-87f8-c5e02d13c686" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_01a0694f-13a1-73a0-a6c3-1bd371de2962" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityAddressCityOrTown_01a0694f-13a1-73a0-a6c3-1bd371de2962" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_01a0694f-13a1-74f9-9e0e-7f77fcb3bf3e" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityAddressStateOrProvince_01a0694f-13a1-74f9-9e0e-7f77fcb3bf3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_01a0694f-13a1-7119-8e3b-c5394d82f8e7" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityAddressPostalZipCode_01a0694f-13a1-7119-8e3b-c5394d82f8e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_01a0694f-13a1-7cac-a310-d9ac34e616ec" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_CityAreaCode_01a0694f-13a1-7cac-a310-d9ac34e616ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_01a0694f-13a1-7c6e-a447-2357688de7de" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_LocalPhoneNumber_01a0694f-13a1-7c6e-a447-2357688de7de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_01a0694f-13a1-7377-83f8-ffabc68a8c14" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_WrittenCommunications_01a0694f-13a1-7377-83f8-ffabc68a8c14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_01a0694f-13a1-75f4-afac-dc32a19232f4" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_SolicitingMaterial_01a0694f-13a1-75f4-afac-dc32a19232f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_01a0694f-13a1-71f1-bbc5-65b8a6591715" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_PreCommencementTenderOffer_01a0694f-13a1-71f1-bbc5-65b8a6591715" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_01a0694f-13a1-7786-bf5c-ae5e69301c72" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_01a0694f-13a1-7786-bf5c-ae5e69301c72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_01a0694f-13a1-7864-abfc-3c1e03852b5c" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_Security12bTitle_01a0694f-13a1-7864-abfc-3c1e03852b5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_01a0694f-13a1-7c9a-ab47-e3a3efa9e593" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_TradingSymbol_01a0694f-13a1-7c9a-ab47-e3a3efa9e593" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_01a0694f-13a1-727d-ab27-be718a8c79ce" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_SecurityExchangeName_01a0694f-13a1-727d-ab27-be718a8c79ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_01a0694f-13a1-7033-bbd7-c4d3b3bcdb21" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a0694f-13a1-73f3-b421-83f6f878a882" xlink:to="loc_dei_EntityEmergingGrowthCompany_01a0694f-13a1-7033-bbd7-c4d3b3bcdb21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
