Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] ACCOUNTS RECEIVABLE Loans, Notes, Trade and Other Receivables, Excluding Allowance for Credit Losses [Text Block] Sales-based Milestone Payments Sales-based Milestone Payments [Member] Sales-based Milestone Payments Trading Arrangement: Trading Arrangement [Axis] Maximum Maximum [Member] Ron Squarer [Member] Ron Squarer Statistical Measurement [Domain] Statistical Measurement [Domain] Title of 12(b) Security Title of 12(b) Security Net Income (loss), diluted Net Income (Loss) Available to Common Stockholders, Diluted Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-Sale [Table] Document Fiscal Year Focus Document Fiscal Year Focus Adjustment to Compensation, Amount Adjustment to Compensation Amount Financial Instrument [Axis] Financial Instrument [Axis] Number of Restricted Stock Units Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Segment Reporting [Abstract] Schedule of Fair Value on a Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Common stock $0.0001 par value; 200,000,000 shares authorized; 95,673,465 and 90,922,868 issued and outstanding as of September 30, 2026 and December 31, 2025, respectively Common Stock, Value, Issued 2027 Lessee, Operating Lease, Liability, to be Paid, Year One Schedule of Long-term Debt Instruments Schedule of Long-Term Debt Instruments [Table Text Block] Royalties Royalty Agreements [Member] Restatement Determination Date Restatement Determination Date Debt instrument, repurchase amount including accrued and unpaid interest Debt Instrument, Repurchase Amount Including Accrued and Unpaid Interest Debt Instrument, Repurchase Amount Including Accrued and Unpaid Interest Tiopronin products Tiopronin Products [Member] Tiopronin Products [Member] Revenue, performance obligation, description of timing Revenue, Performance Obligation, Description of Timing Vested and expected to vest (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Convertible conversion price (in dollars per share) Debt Instrument, Convertible, Conversion Price Amendment Flag Amendment Flag Annual royalty percentage Annual Royalty Percentage Represent percentage of annual royalty. Consolidated Entities [Axis] Consolidated Entities [Axis] Current liabilities: Liabilities, Current [Abstract] Roy Baynes [Member] Roy Baynes Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Disposal Group Classification [Axis] Disposal Group Classification [Axis] Long-term inventory Inventory, Noncurrent Marketable debt securities, available-for-sale, unrealized losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Marketable debt securities, available-for-sale, amortized cost basis, noncurrent Debt Securities, Available-For-Sale, Amortized Cost Basis, Noncurrent Debt Securities, Available-For-Sale, Amortized Cost Basis, Noncurrent Schedule of Short-term Marketable Debt Securities Debt Securities, Available-for-Sale [Table Text Block] Milestone payments paid Business Combination, Cumulative Milestone Payments Paid Under Stock Purchase Agreement Business Combination, Cumulative Milestone Payments Paid Under Stock Purchase Agreement Leases [Abstract] Leases [Abstract] Consolidated Entities [Domain] Consolidated Entities [Domain] Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Entity Address, State or Province Entity Address, State or Province Total, unrealized losses Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Issuance of common stock under the equity incentive plan and proceeds from exercise (in shares) Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Foreign currency translation gain (loss) Foreign currency translation adjustments Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent PEO Total Compensation Amount PEO Total Compensation Amount Number of performance obligations Collaborative Arrangement, Number Of Performance Obligations Collaborative Arrangement, Number Of Performance Obligations Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Assets: Assets, Fair Value Disclosure [Abstract] Intangible assets, net Intangible Asset, Excluding Goodwill, after Accumulated Amortization Accrued expenses Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Weighted average common shares outstanding, basic (in shares) Basic weighted average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Number of reportable segments Number of Reportable Segments Total current liabilities Liabilities, Current Revenue increase (decrease) in performance obligations satisfied in previous period Contract with Customer, Performance Obligation Satisfied in Previous Period Work in process Inventory, Work in Process, Net of Reserves Comprehensive (loss) income: Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Discontinued operations, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted, Discontinued Operations Weighted Average Number of Shares Outstanding, Diluted, Discontinued Operations Continuing operations, basic (in shares) Weighted Average Number of Shares Outstanding, Basic, Continuing Operations Weighted Average Number of Shares Outstanding, Basic, Continuing Operations Entity Address, City or Town Entity Address, City or Town Asset acquisition, consideration transferred Asset Acquisition, Consideration Transferred Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Milestone payments (up to) Collaborative Arrangement, Contingent Milestone Payments From Collaborator Collaborative Arrangement, Contingent Milestone Payments From Collaborator Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Receivables [Abstract] Receivables [Abstract] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Net product sales Cost of goods sold - product sales Total net product sales Product [Member] Net carrying value Intangible Asset, Finite-Lived, after Accumulated Amortization Royalty expense Royalty expense Royalty Expense Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Debt issuance costs, net Debt Issuance Costs, Gross Net Income (loss), basic Net Income (Loss) Available to Common Stockholders, Basic Proceeds from issuances under the employee stock purchase plan Proceeds from Stock Plans Selling, general and administrative Accrued Liabilities, Selling, General, and Administrative, Current Accrued Liabilities, Selling, General, and Administrative, Current Less: accumulated amortization Intangible Asset, Finite-Lived, Accumulated Amortization Significant other observable inputs (Level 2) Fair Value, Inputs, Level 2 [Member] Other income (expense), net: Nonoperating Income (Expense) [Abstract] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Total royalty expense Royalty Expense And Amortization Of Finite Lived Intangible Assets Royalty Expense And Amortization Of Finite Lived Intangible Assets Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Revenue Benchmark Revenue Benchmark [Member] Inducement expense Inducement expense Induced Conversion of Convertible Debt Expense License and collaboration revenue Cost of goods sold - license and collaboration License [Member] United States UNITED STATES Name of Property [Axis] Name of Property [Axis] Concentration Risk Type [Axis] Concentration Risk Type [Axis] Schedule of Long-term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Net cash provided by (used in) operating activities - continuing operations Net cash provided by (used in) operating activities - continuing operations Cash Provided by (Used in) Operating Activity, Continuing Operation Recently Adopted and Issued Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Earnings (Loss) Per Share Earnings Per Share, Policy [Policy Text Block] New Accounting Pronouncements or Change in Accounting Principle [Line Items] New Accounting Pronouncements or Change in Accounting Principle [Line Items] Deferred revenue Increase (Decrease) in Contract with Customer, Liability Schedule of Reportable Segment Loss, Including Significant Expenses Segment Reporting [Table Text Block] Schedule of Cost of Goods Sold Schedule Of Cost Of Goods Sold [Table Text Block] Schedule Of Cost Of Goods Sold Amortization of debt issuance costs Amortization of Debt Issuance Costs Municipal bonds Municipal Bonds [Member] Revenue Recognition and Deductions from Revenue Revenue from Contract with Customer [Policy Text Block] Schedule of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] Discontinued operations, net loss, diluted Net Income (Loss) from Discontinued Operations Available to Common Shareholders, Diluted Research and Development Expenses Research and Development Expense, Policy [Policy Text Block] Total convertible senior notes, net of unamortized debt issuance costs Long-Term Debt Payment of guaranteed minimum royalty Payment Of Guaranteed Minimum Royalty The cash outflow due to guaranteed minimum royalty. Discontinued operations, net loss, basic Net Income (Loss) from Discontinued Operations Available to Common Shareholders, Basic Schedule of Future Minimum Rental Commitments Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Document Period End Date Document Period End Date Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Forfeited/canceled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period Net cash (used in) provided by investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Preferred stock, outstanding (in shares) Preferred Stock, Shares Outstanding Debt instrument, face amount Debt Instrument, Face Amount Number of direct-to-patient pharmacies sold to Number of Direct-To-Patient Pharmacies Sold To Number of Direct-To-Patient Pharmacies Sold To 2028 Lessee, Operating Lease, Liability, to be Paid, Year Two EQUITY OFFERINGS Equity [Text Block] Less: Costs and Expenses [Abstract] Security Exchange Name Security Exchange Name Effective interest percentage Debt Instrument, Interest Rate, Effective Percentage Milestone thresholds Disposal Group, Including Discontinued Operation, Milestone Thresholds Disposal Group, Including Discontinued Operation, Milestone Thresholds Granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Convertible debt Convertible Debt Purchase of marketable debt securities Payments to Acquire Marketable Securities Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax Entity Shell Company Entity Shell Company Operating lease liabilities, current portion Operating Lease, Liability, Current Accrued interest Interest Payable, Current 12 months or greater, fair value Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer NET INCOME (LOSS) PER COMMON SHARE Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Earnings Per Share [Abstract] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Schedule of Weighted Average Number of Shares Schedule of Weighted Average Number of Shares [Table Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Senior Notes Due 2032, Issued Pursuant To Underwriters Option Senior Notes Due 2032, Issued Pursuant To Underwriters Option [Member] Senior Notes Due 2032, Issued Pursuant To Underwriters Option Total liabilities Liabilities Trading Symbol Trading Symbol Variable Interest Entity Consolidation, Variable Interest Entity, Policy [Policy Text Block] Geographical [Domain] Geographical [Domain] Purchase of fixed assets Payments to Acquire Property, Plant, and Equipment Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Company Selected Measure Name Company Selected Measure Name Sale of Stock [Domain] Sale of Stock [Domain] Unrealized (loss) gain on marketable debt securities OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax Percentage of royalty on net sales receives Collaborative Arrangement, Royalty Percentage On Net Sales Collaborative Arrangement, Royalty Percentage On Net Sales Convertible senior notes Long-Term Debt, Gross Beginning balance (in shares) Ending balance (in shares) Shares, Issued In-process research and development Acquired in-process research and development Acquired In Process Research And Development Expense Acquired In Process Research And Development Expense Compensation Amount Outstanding Recovery Compensation Amount Individual: Individual [Axis] Weighted average common shares outstanding, diluted (in shares) Diluted weighted average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Diluted Accounts, Notes, Loans and Financing Receivable [Line Items] Accounts, Notes, Loans and Financing Receivable [Line Items] Disaggregation of Revenue [Line Items] Disaggregation of Revenue [Line Items] Entity Emerging Growth Company Entity Emerging Growth Company Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Disposal Group Name [Domain] Disposal Group Name [Domain] Underlying Security Market Price Change Underlying Security Market Price Change, Percent Commercial paper Commercial Paper [Member] Senior Notes Due 2025 and Senior Notes Due 2029 Senior Notes Due 2025, Senior Notes Due 2029 and Senior Notes Due 2032 [Member] Senior Notes Due 2025, Senior Notes Due 2029 and Senior Notes Due 2032 Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Present value discount Lessee, Operating Lease, Liability, Undiscounted Excess Amount Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Revenue from Contract with Customer [Abstract] Revenue from Contract with Customer [Abstract] Award Timing Predetermined Award Timing Predetermined [Flag] Intangible Asset, Goodwill and Other [Abstract] Intangible Asset, Goodwill and Other [Abstract] Aggregate intrinsic value, exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Debt Securities, Available-for-sale [Line Items] Debt Securities, Available-for-Sale [Line Items] Net cash provided by operating activities - discontinued operations Cash Provided by (Used in) Operating Activity, Discontinued Operation Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Quoted prices in active markets (Level 1) Fair Value, Inputs, Level 1 [Member] Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Conversion ratio Debt Instrument, Convertible, Conversion Ratio Total undiscounted future minimum payments Lessee, Operating Lease, Liability, to be Paid Continuing operations, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted, Continuing Operations Weighted Average Number of Shares Outstanding, Diluted, Continuing Operations Long-term debt, excluding current maturities, repaid if converted Long-term Debt, Excluding Current Maturities, Repayment Amount Upon Conversion Long-term Debt, Excluding Current Maturities, Repayment Amount Upon Conversion Dilutive common share equivalents -restricted stock units and options (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements Beginning balance (in dollars per share) Ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Intangible Assets with Cost Accumulation Model Goodwill and Intangible Assets, Intangible Assets, Policy [Policy Text Block] All Executive Categories All Executive Categories [Member] Regulatory Milestone Regulatory Milestone [Member] Regulatory Milestone Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Scenario [Domain] Scenario [Domain] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Beginning balance (in dollars per share) Ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Operating lease right of use assets Total right-of-use asset Operating Lease, Right-of-Use Asset External research and development External Research and Development External Research and Development Concentration Risk Type [Domain] Concentration Risk Type [Domain] Operating lease extension term Lessee, Operating Lease, Renewal Term Schedule of Basic and Diluted Net Loss Per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Debt Disclosure [Abstract] Debt Disclosure [Abstract] Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] SEGMENT INFORMATION Segment Reporting [Text Block] MARKETABLE DEBT SECURITIES Investment in Debt and Equity Securities and Other Trading Assets [Text Block] Minimum Minimum [Member] Expiration Date Trading Arrangement Expiration Date Schedule of Net Product Revenue Disaggregation of Revenue [Table Text Block] VARIABLE INTEREST ENTITIES Variable Interest Entity Disclosure [Text Block] Effect of exchange rate changes on cash Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Location, Statement of Income, Balance [Axis] Location, Statement of Income, Balance [Axis] Net (loss) income from continuing operations, diluted (in dollars per share) Income (Loss) from Continuing Operations, Per Diluted Share Net (loss) income from continuing operations, basic (in dollars per share) Income (Loss) from Continuing Operations, Per Basic Share Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Cash and cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Remaining Contractual Term (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Debt Conversion Description [Axis] Debt Conversion Description [Axis] Fair value of convertible debt Convertible Debt, Fair Value Disclosures Disposal Group, Including Discontinued Operations [Line Items] Disposal Group, Including Discontinued Operations [Line Items] Business Combination [Line Items] Business Combination [Line Items] Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Common stock, authorized (in shares) Common Stock, Shares Authorized Antidilutive Security, Excluded EPS Calculation [Table] Antidilutive Security, Excluded EPS Calculation [Table] Shares authorized in sale (in shares) Sale of Stock, Number of Shares Issued in Transaction Exercise Price Award Exercise Price Segment Reporting [Line Items] Segment Reporting [Line Items] Payments payable upon achievement of milestones (up to) Payments Payable Upon Achievement Of Milestones Represents substantial payments payable upon the achievement of certain milestones. Unamortized stock compensation expense Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Proceeds from the sale and maturity of marketable debt securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Document Quarterly Report Document Quarterly Report Disposal Groups, Including Discontinued Operations [Table] Disposal Groups, Including Discontinued Operations [Table] Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Segments [Domain] Segments [Domain] CONVERTIBLE DEBT Debt Disclosure [Text Block] Scenario [Axis] Scenario [Axis] Disposal Group Classification [Domain] Disposal Group Classification [Domain] Schedule of Marketable Debt Securities Marketable Securities [Table Text Block] Unamortized debt issuance costs Debt Issuance Costs, Net Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Business Combination [Table] Business Combination [Table] Equity Component [Domain] Equity Component [Domain] PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Market Access Milestone Market Access Milestone [Member] Market Access Milestone Total operating expenses Costs and Expenses Adoption Date Trading Arrangement Adoption Date Capitalization of Inventory Costs Inventory, Policy [Policy Text Block] Interest rate percentage Debt Instrument, Interest Rate, Stated Percentage Counterparty Name [Domain] Counterparty Name [Domain] Total stockholders' equity Beginning balance Ending balance Equity, Attributable to Parent Total other income (expense), net Total other income (expense), net Nonoperating Income (Expense) Milestone payment from collaborator, recognized Collaborative Arrangement, Milestone Payment From Collaborator, Recognized Collaborative Arrangement, Milestone Payment From Collaborator, Recognized Sales discounts, rebates, and allowances Sales Discounts, Rebates, And Allowances, Current Sales Discounts, Rebates, And Allowances, Current Assets Assets [Abstract] Title Trading Arrangement, Individual Title Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Marketable debt securities, available-for-sale, amortized cost Debt Securities, Available-for-Sale, Amortized Cost Accounting Policies [Abstract] Accounting Policies [Abstract] Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Lease liability Total lease liability Operating Lease, Liability Insider Trading Policies and Procedures [Line Items] Beginning balance (in shares) Ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number ACCRUED EXPENSES Accounts Payable and Accrued Liabilities Disclosure [Text Block] Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Performance Shares Performance Shares [Member] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Selling, general and administrative Selling, general and administrative Selling, General and Administrative Expense Repayments of debt Repayments of Debt Business Combination [Domain] Business Combination [Domain] Forfeited/canceled (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Text Block] Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Number of business segments Number of Operating Segments Total anti-dilutive shares (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Dilutive common share equivalents - restricted stock units Restricted stock units Restricted Stock Units (RSUs) [Member] Schedule of Anti-dilutive Securities Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Entity Central Index Key Entity Central Index Key Regulatory and Market Access Milestone Regulatory and Market Access Milestone [Member] Regulatory and Market Access Milestone All Adjustments to Compensation All Adjustments to Compensation [Member] Name of Property [Domain] Name of Property [Domain] Business Combination [Axis] Business Combination [Axis] Equity [Abstract] Equity [Abstract] Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Net cash provided by (used in) operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Repurchase of 2029 convertible senior notes including premium Payments For Repurchase Of Convertible Debt Payments For Repurchase Of Convertible Debt Royalties and milestones capitalized Royalty Costs And Milestones, Capitalized Royalty Costs And Milestones, Capitalized Income Statement [Abstract] Income Statement [Abstract] Stockholders' Equity: Equity, Attributable to Parent [Abstract] Employee stock purchase program purchase and expense (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Document Transition Report Document Transition Report Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Operating expenses: Operating Expenses [Abstract] Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Schedule of Finite-lived Amortizable Intangible Assets Intangible Asset, Finite-Lived [Table Text Block] Shares Underlying Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] City Area Code City Area Code Restricted stock units Restricted Stock [Member] Accumulated Other Comprehensive Loss AOCI Attributable to Parent [Member] Geographic Concentration Risk Geographic Concentration Risk [Member] All Individuals All Individuals [Member] Convertible debt Convertible Debt Securities [Member] Collaborative Arrangement Collaborative Arrangement [Member] Marketable debt securities, available-for-sale, unrealized losses, current Debt Securities Available For Sale Unrealized Loss, Current Debt Securities, Available For Sale, Unrealized Loss, Current Name Forgone Recovery, Individual Name Finished goods Inventory, Finished Goods, Net of Reserves Weighted-average recognition period (in years) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Previously Reported Previously Reported [Member] Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] INTANGIBLE ASSETS Intangible Asset [Text Block] Statement [Line Items] Statement [Line Items] Research and development: Research and Development Expense [Abstract] Total assets Assets Debt Conversion, Scenario Two Debt Conversion, Scenario Two [Member] Debt Conversion, Scenario Two Preferred stock, issued (in shares) Preferred Stock, Shares Issued PTE. Ltd. PTE. Ltd. [Member] PTE. Ltd. Variable Interest Entity, Not Primary Beneficiary Variable Interest Entity, Not Primary Beneficiary [Member] Interest expense Interest expense recognized Interest Expense, Nonoperating Marketable debt securities, available-for-sale, unrealized gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax SHARE-BASED COMPENSATION Share-Based Payment Arrangement [Text Block] Employee stock purchase program expense Stock Issued During Period, Value, Employee Stock Purchase Plan Force majeure event period threshold License Agreement, Force Majeure Event Period Threshold License Agreement, Force Majeure Event Period Threshold Proceeds from issuance of 2032 convertible senior notes Proceeds from Convertible Debt DESCRIPTION OF BUSINESS Nature of Operations [Text Block] PEO PEO [Member] Debt Conversion, Scenario One Debt Conversion, Scenario One [Member] Debt Conversion, Scenario One Total share-based compensation Share-Based Payment Arrangement, Expense Other non-current liabilities Other Liabilities, Noncurrent Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Upfront payment Collaborative Arrangement, Upfront Payment Collaborative Arrangement, Upfront Payment Payables and Accruals [Abstract] Payables and Accruals [Abstract] Disposed of by Sale Discontinued Operations, Disposed of by Sale [Member] Accumulated Deficit Retained Earnings [Member] Operating lease liabilities, less current portion Operating Lease, Liability, Noncurrent Revision of Prior Period [Domain] Revision of Prior Period [Domain] Forfeited/canceled (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Fair Value Measurements Fair Value Measurement, Policy [Policy Text Block] Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Common stock, outstanding (in shares) Common Stock, Shares, Outstanding Award Timing Disclosures [Line Items] Payment of debt issuance costs Payments of Debt Issuance Costs Corporate debt securities Corporate Debt Securities [Member] Net (loss) income per common share, diluted (in dollars per share) Net (loss) income per common share, diluted (in dollars per share) Earnings Per Share, Diluted Entity Current Reporting Status Entity Current Reporting Status Net cash provided by (used in) financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Marketable debt securities, available-for-sale, unrealized gains, current Debt Securities Available For Sale, Unrealized Gain, Current Debt Securities Available For Sale, Unrealized Gain, Current Total Shareholder Return Amount Total Shareholder Return Amount Net income from discontinued operations, diluted (in dollars per share) Income (Loss) from Discontinued Operations and Disposal of Discontinued Operations, Net of Tax, Per Diluted Share Prepaid expenses and other current and non-current assets Increase (Decrease) in Prepaid Expense and Other Assets Consideration receivable on sale of business (up to) Disposal Group, Including Discontinued Operation, Contingent Consideration Receivable Disposal Group, Including Discontinued Operation, Contingent Consideration Receivable Orphan Technologies Limited Orphan Technologies Limited [Member] Orphan Technologies Limited Amortization of intangibles Amortization of intangible assets Intangible Asset, Finite-Lived, Amortization Expense Interest expense associated with convertible debt, net of tax Interest on Convertible Debt, Net of Tax Intangible Asset, Finite-Lived [Line Items] Intangible Asset, Finite-Lived [Line Items] Adjustments to reconcile net loss to net cash provided by (used in) operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Research and development Accrued Liabilities, Research and Development, Current Accrued Liabilities, Research and Development, Current FILSPARI FILSPARI [Member] FILSPARI Total revenue Total net product sales Revenue Revenue from Contract with Customer, Excluding Assessed Tax Property and equipment, net Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Clinical Trial Expenses Clinical Trial Expense [Policy Text Block] Clinical Trial Expense [Policy Text Block] Financial Instruments [Domain] Financial Instruments [Domain] Debt instrument, convertible, prior to maturity date Debt Instrument, Convertible, Redemption Option, Scheduled Trading Days Prior To Maturity Date Debt Instrument, Convertible, Redemption Option, Scheduled Trading Days Prior To Maturity Date INVENTORY Inventory Disclosure [Text Block] Intangible Asset, Finite-Lived, Class [Axis] Intangible Asset, Finite-Lived, Class [Axis] Bile Acid Product Portfolio Bile Acid Product Portfolio [Member] Bile Acid Product Portfolio Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Underlying Securities Award Underlying Securities Amount REVENUE RECOGNITION Revenue from Contract with Customer [Text Block] Amortization of intangibles - royalties and milestones Royalties and Milestine Agreements [Member] Royalties and Milestine Agreements Other Payment for (Proceeds from) Other Investing Activity Inventory Increase (Decrease) in Inventories Weighted-average discount rate Operating Lease, Weighted Average Discount Rate, Percent Mission License Agreement Mission License Agreement [Member] Mission License Agreement Schedule of Service Based Restricted Stock Activity Nonvested Restricted Stock Shares Activity [Table Text Block] Segment Reporting [Table] Segment Reporting [Table] Royalty guarantees, commitments, amount Royalty Guarantees, Commitments, Amount Sale of Stock [Axis] Sale of Stock [Axis] Cash Flows From Investing Activities: Cash Provided by (Used in) Investing Activity, Continuing Operation [Abstract] Remaining Contractual Term (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Schedule of Weighted-average Remaining Lease Term and Discount Rate Lease, Cost [Table Text Block] Cash Flows From Operating Activities: Cash Provided by (Used in) Operating Activity, Continuing Operation [Abstract] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] All Trading Arrangements All Trading Arrangements [Member] Less than 12 months, fair value Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Other Performance Measure, Amount Other Performance Measure, Amount Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Operating (loss) income Operating Income (Loss) Current Fiscal Year End Date Current Fiscal Year End Date Regulatory Development and Sales Based Milestone Regulatory Development And Sales Based Milestone [Member] Regulatory Development And Sales Based Milestone Number of phase 3 clinical trials in process Number Of Phase Three Clinical Trials In Process Number Of Phase Three Clinical Trials In Process Proceeds from issuance of debt Proceeds from Issuance of Debt Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Senior Notes Due 2032 Senior Notes Due 2032 [Member] Senior Notes Due 2032 Ligand License Agreement Ligand License Agreement [Member] Ligand License Agreement under which an entity develop, manufacture and commercialize a drug technology which is referred to as DARA. Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Entity File Number Entity File Number Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Share based compensation Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture Schedule of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Common stock, issued (in shares) Common Stock, Shares, Issued Measure: Measure [Axis] Marketable debt securities, available-for-sale, unrealized losses, noncurrent Debt Securities Available For Sale Unrealized Loss, Noncurrent Debt Securities Available For Sale Unrealized Loss, Noncurrent Share-based payment arrangement, plan modification, incremental cost Share-Based Payment Arrangement, Plan Modification, Incremental Cost Accrued royalties Accrued Royalties, Current 2029 and thereafter Lessee, Operating Lease, Liability, To Be Paid, Year Three And After Year Three Lessee, Operating Lease, Liability, To Be Paid, Year Three And After Year Three Marketable debt securities, available-for-sale, amortized cost, current Debt Securities, Available-For-Sale, Amortized Cost Basis, Current Debt Securities, Available-For-Sale, Amortized Cost Basis, Current 12 months or greater, unrealized losses Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss Marketable debt securities, available-for-sale, current Debt Securities, Available-for-Sale, Current Cash payments in excess of straight-line lease expense Straight Line Lease Expense In Excess Of Cash Payments Straight Line Lease Expense In Excess Of Cash Payments Equity Components [Axis] Equity Components [Axis] Debt instrument, repurchase amount Debt Instrument, Repurchase Amount Accounts receivable Increase (Decrease) in Accounts Receivable Product and Service [Domain] Product and Service [Domain] Class of Stock [Line Items] Class of Stock [Line Items] Disaggregation of Revenue [Table] Disaggregation of Revenue [Table] Entity Interactive Data Current Entity Interactive Data Current Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Senior Notes Due 2029 Senior Notes Due 2029 [Member] Senior Notes Due 2029 Entity Small Business Entity Small Business Comprehensive (loss) income Comprehensive Income (Loss), Net of Tax, Attributable to Parent Termination Date Trading Arrangement Termination Date Discontinued Operations Discontinued Operations, Policy [Policy Text Block] Income from discontinued operations, net of tax Net income from discontinued operations Loss from discontinued operations Income (Loss) from Discontinued Operations, Net of Tax, Attributable to Parent Fair Value, Recurring and Nonrecurring [Table] Fair Value, Recurring and Nonrecurring [Table] Reportable Segment Reportable Segment [Member] Reportable Segment DIVESTITURES Disposal Groups, Including Discontinued Operations, Disclosure [Text Block] Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Other current liabilities Other Liabilities, Current Securities of government sponsored entities Securities of government-sponsored entities US Government-sponsored Enterprises Debt Securities [Member] Collaborative Arrangements Collaborative Arrangement, Accounting Policy [Policy Text Block] Other assets Other Assets, Noncurrent Cash Flows From Financing Activities: Cash Provided by (Used in) Financing Activity, Continuing Operation [Abstract] Document Type Document Type Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Accrued expenses Total accrued expenses Accrued Liabilities, Current Fair Value as of Grant Date Award Grant Date Fair Value Repayment of 2025 convertible senior notes Repayments of Convertible Debt Schedule of Available-for-Sale Marketable Debt Securities in an Unrealized Loss Position Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] BASIS OF PRESENTATION AND SIGNIFICANT ACCOUNTING POLICIES Significant Accounting Policies [Text Block] Aggregate Intrinsic Value (in thousands) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Aggregate Intrinsic Value [Roll Forward] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Aggregate Intrinsic Value Aggregate intrinsic value, exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Arrangement Duration Trading Arrangement Duration Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Local Phone Number Local Phone Number Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Registrant Name Entity Registrant Name Less than 12 months, unrealized losses Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss Schedule of Performance Based Restricted Stock Activity Share-Based Payment Arrangement, Performance Shares, Activity [Table Text Block] (Loss) income from continuing operations before income tax Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Aggregate intrinsic value, vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Commitments and Contingencies (See Note 13) Commitments and Contingencies Gross carrying amount Finite-lived intangible assets Intangible Asset, Finite-Lived, before Accumulated Amortization Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Chugai Chugai [Member] Chugai Unamortized debt issuance costs Adjustments To Additional Paid In Capital, Convertible Debt Instrument, Unamortized Debt Issuance Costs Adjustments To Additional Paid In Capital, Convertible Debt Instrument, Unamortized Debt Issuance Costs Accounting Standards Update and Change in Accounting Principle [Table] Accounting Standards Update and Change in Accounting Principle [Table] Accounts payable Increase (Decrease) in Accounts Payable and Accrued Liabilities Continuing operations, net loss, diluted Net Income (Loss) from Continuing Operations Available to Common Shareholders, Diluted Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Executive Category: Executive Category [Axis] Counterparty Name [Axis] Counterparty Name [Axis] Liabilities and Stockholders' Equity Liabilities and Equity [Abstract] Intangible Asset, Finite-Lived, Class [Domain] Intangible Asset, Finite-Lived, Class [Domain] Exercisable (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term Total inventory Inventory, Net Award Type [Domain] Award Type [Domain] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount 2026 (remaining) Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year FAIR VALUE MEASUREMENTS Fair Value Disclosures [Text Block] Significant unobservable inputs (Level 3) Fair Value, Inputs, Level 3 [Member] PEO Name PEO Name Debt instrument, convertible, threshold percentage of stock price trigger Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger Geographical [Axis] Geographical [Axis] Deferred revenue Contract with Customer, Liability Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Entity Tax Identification Number Entity Tax Identification Number Total interest expense Interest Expense, Debt Notes payable Notes Payable Marketable debt securities, available-for-sale, noncurrent Debt Securities, Available-for-Sale, Noncurrent Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Cash and cash equivalents, beginning of year Cash and cash equivalents, end of period Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Intangible Asset, Finite-Lived [Table] Intangible Asset, Finite-Lived [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Vifor Pharma Vifor Ltd. [Member] Vifor Ltd. Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Non-NEOs Non-NEOs [Member] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Net income from discontinued operations, basic (in dollars per share) Income (Loss) from Discontinued Operations and Disposal of Discontinued Operations, Net of Tax, Per Basic Share Debt Instrument [Axis] Debt Instrument [Axis] Share based compensation Share-Based Payment Arrangement, Noncash Expense Discontinued operations, basic (in shares) Weighted Average Number of Shares Outstanding, Basic, Discontinued Operations Weighted Average Number of Shares Outstanding, Basic, Discontinued Operations Proceeds from milestone payment Disposal Group, Including Discontinued Operation, Proceeds From Milestone Payment Disposal Group, Including Discontinued Operation, Proceeds From Milestone Payment Disposal Group Name [Axis] Disposal Group Name [Axis] Schedule of Inventory Schedule of Inventory, Current [Table Text Block] LEASES Lessee, Operating Leases [Text Block] Long-term Debt, Type [Domain] Long-Term Debt, Type [Domain] Net (loss) income per common share, basic (in dollars per share) Net (loss) income per common share, basic (in dollars per share) Earnings Per Share, Basic Total current assets Assets, Current Statistical Measurement [Axis] Statistical Measurement [Axis] Insider Trading Arrangements [Line Items] Long-term debt, excluding current maturities Long-Term Debt, Excluding Current Maturities Award Type [Axis] Award Type [Axis] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Accounts receivable, net Accounts Receivable, after Allowance for Credit Loss, Current Office Lease 2020 Office Lease 2020 [Member] Office Lease 2020 Issuance of common stock under the equity incentive plan and proceeds from exercise Shares Granted, Value, Share-Based Payment Arrangement, before Forfeiture Unrealized (loss) gain on marketable debt securities Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Accumulated deficit Retained Earnings (Accumulated Deficit) Product and Service [Axis] Product and Service [Axis] Debt instrument, convertible, threshold trading days Debt Instrument, Convertible, Threshold Trading Days Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Common Stock Common Stock [Member] Marketable debt securities, at fair value Total available-for-sale marketable debt securities Marketable debt securities, available-for-sale, aggregate estimated fair value Marketable debt securities, available-for-sale Debt Securities, Available-for-Sale Contingent consideration, liability Business Combination, Contingent Consideration, Liability Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Cover [Abstract] Cover [Abstract] Marketable debt securities, available-for-sale, unrealized gains, noncurrent Debt Securities, Available For Sale Unrealized Gain, Noncurrent Debt Securities, Available For Sale Unrealized Gain, Noncurrent Internal personnel costs Internal Personnel Costs For Research And Development Internal Personnel Costs For Research And Development Contractual interest expense Interest Expense, Debt, Excluding Amortization Concentration risk, percentage Concentration Risk, Percentage Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Equity Awards Adjustments Equity Awards Adjustments [Member] COLLABORATION AND LICENSE AGREEMENTS Collaborative Arrangement Disclosure [Text Block] Total liabilities and stockholders' equity Liabilities and Equity Compensation related costs Accrued Salaries, Current Dilutive common share equivalents - options Options Share-Based Payment Arrangement, Option [Member] Segments [Axis] Segments [Axis] Other current and non-current liabilities Increase (Decrease) in Other Operating Liabilities Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Accrued interest receivable Interest Receivable, Current Inventory Disclosure [Abstract] Inventory Disclosure [Abstract] Tabular List, Table Tabular List [Table Text Block] Additional paid-in capital Additional Paid in Capital Schedule of Share Based Compensation Expenses Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Purchase of intangible assets Payments to date under terms of agreement Payments to Acquire Intangible Assets Other (expense) income, net Other Nonoperating Income (Expense) Dilutive common share equivalents - convertible debt (in shares) Incremental Common Shares Attributable to Dilutive Effect of Conversion of Debt Securities Name Awards Close in Time to MNPI Disclosures, Individual Name Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Aggregate intrinsic value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Forfeited/canceled (in shares) Forfeited/canceled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Preferred stock, authorized (in shares) Preferred Stock, Shares Authorized Preferred stock $0.0001 par value; 20,000,000 shares authorized; no shares issued and outstanding as of September 30, 2026 and December 31, 2025 Preferred Stock, Value, Issued Adjustment to Compensation: Adjustment to Compensation [Axis] Cost of goods sold Cost of Goods and Service [Policy Text Block] At-The-Market Offering At-The-Market Offering [Member] At-The-Market Offering Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Total Assets, Fair Value Disclosure Vested and expected to vest (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Discontinued Operations and Disposal Groups [Abstract] Discontinued Operations and Disposal Groups [Abstract] Name Measure Name Accounts payable Accounts Payable, Current Pay vs Performance Disclosure [Line Items] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Other Other Noncash Income (Expense) Debt Instrument [Line Items] Debt Instrument [Line Items] Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Available-for-sale marketable debt securities in an unrealized loss position Debt Securities, Available-for-sale, Unrealized Loss Position, Amortized Cost Debt Securities, Available-for-sale, Unrealized Loss Position, Amortized Cost Additional Paid in Capital Additional Paid-in Capital [Member] Entity Filer Category Entity Filer Category Total, fair value Debt Securities, Available-for-Sale, Unrealized Loss Position Unamortized lease incentives Operating Lease, Incentive, Tenant Improvements Operating Lease, Incentive, Tenant Improvements Revision of Prior Period [Axis] Revision of Prior Period [Axis] Miscellaneous accrued expenses Accrued Liabilities, Miscellaneous, Current Accrued Liabilities, Miscellaneous, Current Name Trading Arrangement, Individual Name Cash and cash equivalents Cash and Cash Equivalent Raw materials Inventory, Raw Materials, Net of Reserves Induced conversion on 2029 Notes Induced conversion on 2029 Notes Adjustment To Additional Paid-in Capital, Induced Debt Conversion With Cash Adjustment To Additional Paid-in Capital, Induced Debt Conversion With Cash Operating lease expense Operating Lease, Expense Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Company Selected Measure Amount Company Selected Measure Amount Beginning balance (in shares) Ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number Investments, Debt and Equity Securities [Abstract] Investments, Debt and Equity Securities [Abstract] Depreciation and amortization Depreciation, Depletion and Amortization Vested and expected to vest (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Continuing operations, net loss, basic Net Income (Loss) from Continuing Operations Available to Common Shareholders, Basic Lease incentive, tenant improvements Incentive to Lessee Inventory Current inventory Inventory, Gross Entity Address, Address Line Two Entity Address, Address Line Two Stock, Class of Stock [Table] Stock, Class of Stock [Table] Accounts and Financing Receivables [Table] Accounts and Financing Receivables [Table] Current assets: Assets, Current [Abstract] Aggregate offering amount authorized Sale of Stock, Aggregate Offering Amount Authorized Sale of Stock, Aggregate Offering Amount Authorized Debt Conversion, Name [Domain] Debt Conversion, Name [Domain] Weighted-average remaining lease term in years Operating Lease, Weighted Average Remaining Lease Term Non-PEO NEO Non-PEO NEO [Member] Senior Notes Due 2025 Senior Notes Due 2025 [Member] Senior Notes Due 2025 [Member] Senior Notes Senior Notes [Member] Entity Address, Address Line One Entity Address, Address Line One Vested (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Per share data Earnings Per Share Basic And Diluted [Abstract] Earnings Per Share Basic And Diluted Income tax benefit (provision) on continuing operations Income tax benefit (provision) Income Tax Expense (Benefit) Foreign currency remeasurement impact Gain (Loss), Foreign Currency Transaction, before Tax Cost of goods sold Total cost of goods sold Cost of Product and Service Sold Award Timing Method Award Timing Method [Text Block] Principles of Consolidation Consolidation, Policy [Policy Text Block] Net increase in cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Other research and development Other Research and Development Expense Forecast Forecast [Member] Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Research and development Total research and development Research and Development Expense (Excluding Acquired in Process Cost) Net (loss) income Net (loss) income Net (loss) income Net loss Net Income (Loss) Attributable to Parent Senior Notes Due 2029, Issued Pursuant to Underwriters Option Senior Notes Due 2029, Issued Pursuant To Underwriters Option [Member] Senior Notes Due 2029, Issued Pursuant To Underwriters Option Long-term Debt, Type [Axis] Long-Term Debt, Type [Axis] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Statement [Table] Statement [Table] Restatement Determination Date: Restatement Determination Date [Axis] Proceeds from exercise of stock options Proceeds from Stock Options Exercised Schedule of Royalty Expense Schedule Of Royalty Expense [Table Text Block] Schedule Of Royalty Expense Interest income Investment Income, Interest Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Variable interest entity, gain from sale Variable Interest Entity, Gain From Sale Variable Interest Entity, Gain From Sale Debt instrument, convertible, threshold consecutive trading days Debt Instrument, Convertible, Threshold Consecutive Trading Days (Loss) income from continuing operations, net of tax Net loss from continuing operations Income (Loss) from Continuing Operations, Net of Tax, Attributable to Parent Acquisition of in-process research and development Payment of Licensing Agreement Milestone, Investing Activities Payment of Licensing Agreement Milestone, Investing Activities Long-term debt, term Long-Term Debt, Term Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]