1900 K Street, NW Washington, DC 20006-1110 +1 202 261 3300 Main +1 202 261 3333 Fax www.dechert.com
						ADAM T. TEUFEL   adam.teufel@dechert.com +1 202 261 3464 Direct +1 202 261 3164 Fax

October 30, 2026

VIA EDGAR

U.S. Securities and Exchange Commission

100 F Street, NE

Washington, D.C. 20549-4720

 

Re:

Nuveen Investment Trust (the “Registrant”)

(File Nos. 333-03715 and 811-07619)

Ladies and Gentlemen:

On behalf of the Registrant, in accordance with the provisions of Rule 497(j) of Regulation C under the Securities Act of 1933 (the “Securities Act”), this letter serves to certify that the most recent amendment to the Registration Statement on Form N-1A (the “Registration Statement”) of the Registrant and certain of its series, namely Nuveen Global Equity Income Fund, Nuveen Multi Cap Value Fund, Nuveen Large Cap Value Opportunities Fund, Nuveen Small/Mid Cap Value Fund and Nuveen Small Cap Value Opportunities Fund, does not differ from that which would have been filed pursuant to Rule 497(c) of the Securities Act. Post-Effective Amendment No. 153, which was the most recent amendment to the Registration Statement, was filed electronically with the Securities and Exchange Commission on October 30, 2026.

Please contact the undersigned at (202) 261-3464 if you have any questions regarding this certification.

Sincerely,

/s/ Adam T. Teufel

Adam T. Teufel