v3.26.3
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE (LOSS) INCOME - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2026
Sep. 30, 2025
Sep. 30, 2026
Sep. 30, 2025
Revenues:        
Total revenues $ 1,458,086 $ 1,249,026 $ 3,916,209 $ 2,616,904
Operating costs and expenses:        
Cost of goods sold 361,750 197,231 867,531 409,443
Cost of collaborations and royalties 0 2,923 3,792 4,705
Research and development 408,538 358,814 1,186,538 947,557
Selling, general and administrative 342,000 322,076 1,012,473 885,339
Total operating costs and expenses 1,112,288 881,044 3,070,334 2,247,044
Income from operations 345,798 367,982 845,875 369,860
Other (expense) income:        
Interest expense (84,372) (67,462) (235,709) (187,227)
Interest income 30,941 28,681 85,682 84,840
Loss related to convertible debt 0 (39,146) 0 (39,146)
Other income (expense), net 3,443 (9,487) (579) 8,564
Total other expense, net (49,988) (87,414) (150,606) (132,969)
Income before income taxes 295,810 280,568 695,269 236,891
Benefit from (provision for) income taxes 1,871,525 12,115 1,842,551 (34,687)
Net income $ 2,167,335 $ 292,683 $ 2,537,820 $ 202,204
Net income per common share — basic (in dollars per share) $ 16.19 $ 2.23 $ 19.02 $ 1.55
Net income per common share — diluted (in dollars per share) $ 15.72 $ 2.14 $ 18.42 $ 1.51
Weighted-average common shares - basic (in shares) 133,828 131,447 133,444 130,590
Weighted-average common shares - diluted (in shares) 138,040 137,348 138,184 134,146
Statements of Comprehensive Income        
Net income $ 2,167,335 $ 292,683 $ 2,537,820 $ 202,204
Other comprehensive (loss) income:        
Unrealized (losses) gains on marketable securities (11,811) 1,131 (19,098) 1,818
Foreign currency translation (losses) gains (801) 6,993 (5,733) 10,764
Defined benefit pension plans, net of tax 89 53 267 161
Total other comprehensive (loss) income (12,523) 8,177 (24,564) 12,743
Comprehensive income 2,154,812 300,860 2,513,256 214,947
Net product revenues        
Revenues:        
Total revenues 1,291,946 851,082 3,500,182 1,991,832
Net revenues from collaborations        
Revenues:        
Total revenues 71,476 351,742 200,716 512,423
Royalty revenue        
Revenues:        
Total revenues $ 94,664 $ 46,202 $ 215,311 $ 112,649