v3.26.3
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2026
Sep. 30, 2025
Cash flows from operating activities    
Net Income (Loss) $ 28,994 $ 817,609
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and amortization 48,104 25,913
Non-cash operating lease expense 5,358 5,635
Non-cash royalty revenue related to sale of future royalties (199,624) (149,160)
Non-cash interest expense on liability related to sale of future royalties 196,861 149,305
Change in valuation of contingent consideration   (800)
Tangible asset impairment and losses on transactions, net 927 648
Inducement expense related to repurchase of 2026 Convertible Notes 3,386  
Unrealized gain on ClearPoint Equity Investments   (5,734)
Unrealized gain on marketable securities - equity investments (3,018) (3,160)
Disposal of asset   163
Deferred income taxes   (4)
Amortization of discounts on investments, net (13,600) (12,972)
Amortization of debt issuance costs 1,459 906
Loss on extinguishment of debt 19,263  
Share-based compensation expense 70,539 56,029
Unrealized foreign currency transaction losses, net 637 4,768
Changes in operating assets and liabilities:    
Inventory, net (31,332) (27,117)
Prepaid expenses and other current assets 4,858 (13,876)
Trade and royalty receivables, net (60,076) (32,365)
Deposits and other assets (635) 1,501
Accounts payable and accrued expenses (20,521) (36,341)
Other liabilities (6,827) (26,497)
Deferred revenue 7 (4,298)
Payments on contingent consideration   (4,684)
Net cash provided by operating activities 44,760 745,469
Cash flows from investing activities    
Purchases of fixed assets (6,046) (6,486)
Proceeds from sale of fixed assets   70
Purchases of marketable securities- available for sale (1,674,893) (1,051,267)
Purchases of marketable securities- equity investments (38,864) (46,537)
Sale of marketable securities- available for sale 1,029,918 424,351
Sale of marketable securities- equity investments 39,655 40,112
Acquisition of product rights and licenses (8,474) (256,235)
Net cash used in investing activities (658,704) (895,992)
Cash flows from financing activities    
Proceeds from exercise of options 24,986 33,715
Proceeds from employee stock purchase plan 3,163 2,827
Repurchase of the 2026 Convertible Notes (402,653)  
Conversion of the 2026 Convertible Notes (12,879)  
Debt issuance costs related to 2031 Convertible Notes (14,572)  
Proceeds from issuance of 2031 Convertible Notes 550,000  
Payments on contingent consideration obligation   (6,341)
Payments on finance lease principal (3,000) (1,611)
Net cash provided by financing activities 145,045 28,590
Effect of exchange rate changes on cash (4,100) 12,917
Net decrease in cash and cash equivalents (472,999) (109,016)
Cash and cash equivalents, and restricted cash beginning of period 998,334 795,316
Cash and cash equivalents, and restricted cash end of period 525,335 686,300
Supplemental disclosure of cash information    
Cash paid for interest 3,433 5,702
Foreign:    
Income tax paid, Foreign 950  
Total income taxes paid, net of refunds received 8,973 40,124
Supplemental disclosure of non-cash investing and financing activity    
Unrealized (loss) gain on marketable securities, net of tax (4,781) 402
Right-of-use assets obtained in exchange for operating lease obligations   27,675
Decrease in right-of-use assets related to lease modifications and termination 1,466  
Decrease in operating lease liabilities due to lease modifications and termination 1,547  
Acquisition of product rights and licenses 4,657 2,221
Fixed asset additions through tenant improvement allowance   766
Milestone payable 80,000 $ 32,500
Illinois    
State:    
Income tax paid, State 6,570  
Florida    
State:    
Income tax paid, State 1,300  
Other State    
State:    
Income tax paid, State $ 153