Stock award plan - Share-based compensation expense (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
Sep. 30, 2026	Sep. 30, 2025	Sep. 30, 2026	Sep. 30, 2025
Stock option plan
Share-based compensation expense	$ 23,827	$ 19,426	$ 70,539	$ 56,029
Research and development
Stock option plan
Share-based compensation expense	10,479	9,133	32,155	26,827
Selling, general and administrative
Stock option plan
Share-based compensation expense	$ 13,348	$ 10,293	$ 38,384	$ 29,202

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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+ Details