Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Shares used in calculation of earnings per share: Weighted Average Number of Shares Outstanding, Diluted [Abstract] Trading Arrangement: Trading Arrangement [Axis] Maximum Maximum [Member] Floating Rate Notes Due 2028 Floating Rate Notes Due 2028 [Member] Floating Rate Notes Due 2028 Portion at Fair Value Measurement Portion at Fair Value Measurement [Member] Statistical Measurement [Domain] Statistical Measurement [Domain] Title of 12(b) Security Title of 12(b) Security Carrying Amount Reported Value Measurement [Member] Subsequent Event Subsequent Event [Member] Document Fiscal Year Focus Document Fiscal Year Focus Adjustment to Compensation, Amount Adjustment to Compensation Amount Financial Instrument [Axis] Financial Instrument [Axis] Segment Reporting [Abstract] Segment Reporting [Abstract] Schedule of Fair Value Measurement Fair Value, Assets Measured on Recurring Basis [Table Text Block] Common stock Common Stock, Value, Issued Employee compensation Employee-related Liabilities, Current Schedule of Long-Term Notes Schedule of Long-Term Debt Instruments [Table Text Block] Line of Credit Line of Credit [Member] Restatement Determination Date Restatement Determination Date 0.625% Notes due 2031 0.625% Notes Due 2031 [Member] 0.625% Notes due 2031 [Member] Derivative Instrument [Axis] Derivative Instrument [Axis] 2.125% Notes due 2030 2.125% Notes Due June 3, 2030 [Member] 2.125% Notes Due June 3, 2030 [Member] Cash paid for acquisitions, net of cash acquired Other Payments to Acquire Businesses Amendment Flag Amendment Flag Current Liabilities Liabilities, Current [Abstract] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Other assets and liabilities, net Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Other Assets (Liabilities), Net Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Other Assets (Liabilities), Net Loss Contingencies [Table] Loss Contingencies [Table] Floating Rate Notes Floating Rate Notes [Member] Floating Rate Notes Purchases of property and equipment Payments to Acquire Other Property, Plant, and Equipment Total noncurrent liabilities Liabilities, Noncurrent Change in deferred income taxes Increase (Decrease) in Deferred Income Taxes Other equity Other Additional Capital Foreign Currency-Denominated Notes Foreign Currency-Denominated Notes [Member] Foreign Currency-Denominated Notes Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Entity Address, State or Province Entity Address, State or Province PEO Total Compensation Amount PEO Total Compensation Amount Debt Instrument, Redemption, Period [Axis] Debt Instrument, Redemption, Period [Axis] Expenditures for long-lived assets Segment Reporting, Long-Lived Asset, Expenditure for Addition Asset Acquisition [Axis] Asset Acquisition [Axis] Orna Therapeutics, Inc. (Orna) Orna Therapeutics, Inc. [Member] Orna Therapeutics, Inc. Noncurrent Liabilities Liabilities, Noncurrent [Abstract] Other intangibles, net Intangible Asset, Excluding Goodwill, after Accumulated Amortization Share Repurchase Program [Domain] Share Repurchase Program [Domain] Derivative, notional amount Derivative, Notional Amount Basic (in shares) Weighted Average Number of Shares Outstanding, Basic Investments Noncurrent investments Long-Term Investments Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Loss Contingencies [Line Items] Loss Contingencies [Line Items] Collaborative Arrangements and Non-collaborative Arrangement Transactions [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Number of reportable segments Number of Reportable Segments Total current liabilities Liabilities, Current Schedule of Significant Foreign Currency Contracts Schedule of Derivative Instruments [Table Text Block] Entity Address, City or Town Entity Address, City or Town Estimated fair value as of acquisition date: Business Combination, Contingency Recognized at Acquisition Date, Liability to Asset, Excess (Less), Fair Value [Abstract] Jardiance Jardiance Jardiance [Member] Jardiance [Member] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Document Information [Line Items] Document Information [Line Items] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] One Time Payment One Time Payment [Member] One Time Payment Net product revenue Product [Member] Class of Stock [Axis] Class of Stock [Axis] Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Significant Other Observable Inputs (Level 2) Fair Value, Inputs, Level 2 [Member] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Other comprehensive income (loss) Other Comprehensive Income (Loss), Net of Tax Line of credit facility value Line of Credit Facility, Maximum Borrowing Capacity Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] U.S. UNITED STATES Subsequent Event Type [Axis] Subsequent Event Type [Axis] Effect of Change in Accounting Estimate, Type [Domain] Effect of Change in Accounting Estimate, Type [Domain] Schedule of Long-Term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Implementation of New Financial Accounting Standards New Accounting Pronouncements, Policy [Policy Text Block] Litigation Case [Axis] Litigation Case [Axis] Schedule of Segment Reporting Segment Reporting [Table Text Block] Acquisitions Asset Acquisition [Text Block] Other comprehensive income, net of tax Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Financial Information Regularly Reviewed by the CODM Segment Reporting, Profit (Loss) [Abstract] Acquired in-process research and development (IPR&D) Business Combination, Recognized Asset Acquired, Identifiable Intangible Asset, Excluding Goodwill Long-term debt Long-term debt, including current portion Long-Term Debt Document Period End Date Document Period End Date Net Cash Used for Investing Activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Equity Equity [Text Block] Costs, expenses, and other: Costs and Expenses [Abstract] Security Exchange Name Security Exchange Name Debt instrument, term Debt Instrument, Term Expected price of acquisition Business Combination, Price of Acquisition, Expected Position [Axis] Position [Axis] Merida Biosciences, Inc. Merida Biosciences, Inc. [Member] Merida Biosciences, Inc. Subsidiary or Equity Method Investee [Line Items] Subsidiary or Equity Method Investee [Line Items] Increase to last-in, first-out cost Inventory, LIFO Reserve Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax Entity Shell Company Entity Shell Company Statement of Comprehensive Income [Abstract] Statement of Comprehensive Income [Abstract] Name Outstanding Recovery, Individual Name Earnings per share: Earnings Per Share [Abstract] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Trading Symbol Trading Symbol Geographical [Domain] Geographical [Domain] Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Schedule of Recognized Identified Assets Acquired and Liabilities Assumed Business Combination, Recognized Asset Acquired and Liability Assumed [Table Text Block] Company Selected Measure Name Company Selected Measure Name Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] SiteOne Therapeutics, Inc.(SiteOne) SiteOne Therapeutics, Inc. [Member] SiteOne Therapeutics, Inc. 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interest rate (in percent) Debt Instrument, Interest Rate, Stated Percentage Total equity Beginning balance Ending balance Equity, Attributable to Parent Less: Less Significant Expenses [Abstract] Less Significant Expenses Other–net, (income) expense Nonoperating Income (Expense) Other immunology Other Immunology [Member] Other Immunology [Member] Assets Assets [Abstract] Title Trading Arrangement, Individual Title Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Insider Trading Policies and Procedures [Line Items] Other financing activities, net Proceeds from (Payment for) Other Financing Activity Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Long-term income taxes payable Accrued Income Taxes, Noncurrent Marketing, selling, and administrative Selling, General and Administrative Expense Anat Hakim [Member] Anat Hakim May 2026 May 2026 Issuance Date Debt [Member] May 2026 Issuance Date Debt Business Combination [Domain] Business Combination [Domain] Asset impairment, restructuring, and other special charges Asset impairment, restructuring, and other special charges Restructuring, Settlement and Impairment Provisions Contingencies Commitments and Contingencies Disclosure [Text Block] Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Entity Central Index Key Entity Central Index Key Property and equipment, accumulated depreciation Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization Additional paid-in capital Additional Paid in Capital, Common Stock All Adjustments to Compensation All Adjustments to Compensation [Member] Other operating activities, net Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Other Item Business Combination [Axis] Business Combination [Axis] Equity [Abstract] Equity [Abstract] Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Net Cash Provided by Operating Activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Other Stockholders' Equity, Other Ventyx Ventyx Biosciences, Inc [Member] Ventyx Biosciences, Inc Income Statement [Abstract] Income Statement [Abstract] Issuance of stock under employee stock plans, net (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Transition Report Document Transition Report Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Designated as accounting hedges Designated as Hedging Instrument [Member] Deferred tax assets Deferred Income Tax Assets, Net Stock Appreciation Rights (SARs) 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Description Non-GAAP Measure Description [Text Block] Total assets Assets Entity [Domain] Entity [Domain] Ilya Yuffa [Member] Ilya Yuffa Rest of world Rest Of World [Member] Rest Of World Zepbound Zepbound [Member] Zepbound Interest expense Interest Expense, Nonoperating Equity investments without readily determinable fair values Equity Securities without Readily Determinable Fair Value, Amount Issuance of stock under employee stock plans, net Stock Issued During Period, Value, Employee Stock Purchase Plan Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] PEO PEO [Member] Purchases of common stock (in shares) Stock Repurchased and Retired During Period, Shares Measurement Basis [Axis] Measurement Basis [Axis] Other noncurrent liabilities Other Liabilities, Noncurrent Goodwill Goodwill Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Subsequent Event Type [Domain] Subsequent Event Type [Domain] Retained Earnings Retained Earnings [Member] Employee benefit trust Common Stock, Shares Held in Employee Trust 0.500% Notes due 2033 0.500% Notes Due 2033 [Member] 0.500% Notes Due 2033 [Member] Cash Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Increase (Decrease) in Shareholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Award Timing Disclosures [Line Items] Foreign Currency Translation Accumulated Foreign Currency Adjustment Attributable to Parent [Member] Diluted (in dollars per share) Earnings Per Share, Diluted Accumulated Other Comprehensive Income (Loss) [Table] Accumulated Other Comprehensive Income (Loss) [Table] Entity Current Reporting Status Entity Current Reporting Status Net Cash (Used for) Provided by Financing Activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Total Shareholder Return Amount Total Shareholder Return Amount Curevo Inc. (Curevo) Curevo Inc. [Member] Curevo Inc. Litigation Case Type [Domain] Litigation Case [Domain] Schedule of Short-term and Long-term Classification and Contingent Consideration Liabilities Fair Value, Liabilities Measured on Recurring Basis [Table Text Block] Adjustments to Reconcile Net Income to Cash Flows from Operating Activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Marketable equity securities Marketable Securities [Member] Marketable Securities [Member] Edgardo Hernandez [Member] Edgardo Hernandez Cash Flows from Financing Activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Property and equipment, net of accumulated depreciation of $13,373 (2026) and $12,560 (2025) Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Schedule of Components of Equity Schedule of Stockholders Equity [Table Text Block] Financial Instruments [Domain] Financial Instruments [Domain] AtaiBeckley Inc. (AtaiBeckley) AtaiBeckley, Inc. [Member] AtaiBeckley, Inc. Cardiometabolic Health Cardiometabolic Health [Member] Cardiometabolic Health Inventories Inventory Disclosure [Text Block] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Underlying Securities Award Underlying Securities Amount Fair Value Measurements Using Estimate of Fair Value Measurement [Member] Revenue Revenue from Contract with Customer [Text Block] Prepaid expenses Prepaid Expense, Current Other investing activities, net Payment for (Proceeds from) Other Investing Activity Segment Reporting [Table] Segment Reporting [Table] Maturity Date, 2027 Maturity Date, 2027 [Member] Maturity Date, 2027 Other current liabilities Business Combination, Contingent Consideration, Liability, Current Other current assets Other Assets, Current Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] All Trading Arrangements All Trading Arrangements [Member] Other Performance Measure, Amount Other Performance 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short-term borrowings Proceeds from (Repayments of) Short-Term Debt Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Beginning balance (in shares) Ending balance (in shares) Common Stock, Shares, Issued Measure: Measure [Axis] Finished products Inventory, Finished Goods, Gross 1.625% Notes due 2043 1.625% Notes Due 2043 [Member] 1.625% Notes Due 2043 Short-term investments Debt Securities, Available-for-Sale, Current Equity Components [Axis] Equity Components [Axis] Product and Service [Domain] Product and Service [Domain] Disaggregation of Revenue [Table] Disaggregation of Revenue [Table] Common Stock (no par value) Common Class A [Member] Multi Year Credit Facility Multi Year Credit Facility [Member] Multi Year Credit Facility Entity Interactive Data Current Entity Interactive Data Current Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Recognized in other–net, (income) expense: Derivative Instruments Not 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Late-stage Late-Stage [Member] Late-Stage Income before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Commitments and Contingencies Commitments and Contingencies Revenue Revenue Revenues Debt Instrument, Redemption, Period [Domain] Debt Instrument, Redemption, Period [Domain] Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Executive Category: Executive Category [Axis] China CHINA Acquired IPR&D Charge Payments for Asset Acquisitions Payments for Asset Acquisitions Ajax Therapeutics, Inc. (Ajax) Ajax Therapeutics, Inc. [Member] Ajax Therapeutics, Inc. 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[Abstract] Business Combination, Cash Acquired Noncurrent Assets Assets, Noncurrent [Abstract] Cost Portion at Other than Fair Value Measurement [Member] Adjustment to Compensation: Adjustment to Compensation [Axis] Share Repurchase Program [Axis] Share Repurchase Program [Axis] Hedging Designation [Domain] Hedging Designation [Domain] Class of Stock [Domain] Class of Stock [Domain] Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Prepaid taxes Prepaid Taxes Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Foreign Exchange Forward Foreign Exchange Forward [Member] Hedging Designation [Axis] Hedging Designation [Axis] Credit Facility [Axis] Credit Facility [Axis] Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Name Measure Name Income Taxes Income Tax Disclosure [Text Block] Accounts payable Accounts Payable, Current Pay vs Performance Disclosure [Line Items] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Debt Instrument [Line Items] Debt Instrument [Line Items] Schedule of Effects of Significant Risk-Management Programs Schedule of Derivatives Instruments Statements of Financial Performance and Financial Position, Location [Table Text Block] Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Cash paid or to be paid, net of cash acquired Business Combination, Consideration Transferred Additional Paid-in Capital Additional Paid-in Capital [Member] Entity Filer Category Entity Filer Category Subsidiary or Equity Method Investee, Sale of Stock [Table] Subsidiary or Equity Method Investee, Sale of Stock [Table] Name Trading Arrangement, Individual Name Neuroscience Neuroscience [Member] Revenue to unaffiliated customers, Neuroscience Cash and cash equivalents Cash and Cash Equivalent 1.375% Notes due 2061 1.375% Notes Due 2061 [Member] 1.375% Notes Due 2061 Position [Domain] Position [Domain] Company Selected Measure Amount Company Selected Measure Amount Not designated as accounting hedges Not Designated as Hedging Instrument [Member] Kelonia Kelonia Therapeutics [Member] Kelonia Therapeutics Depreciation and amortization Depreciation, Depletion and Amortization Total (approximates replacement cost) Inventory, Gross 6.77% Notes due 2036 6.77% Notes Due January 1, 2036 [Member] 6.77% Notes Due January 1, 2036 [Member] Net income (loss) Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Current Assets Assets, Current [Abstract] Non-PEO NEO Non-PEO NEO [Member] Entity Address, Address Line One Entity Address, Address Line One Income taxes Income Tax Expense (Benefit) Mounjaro Mounjaro [Member] Mounjaro [Member] Cost of sales Cost of Product and Service Sold Award Timing Method Award Timing Method [Text Block] Other Product and Service, Other [Member] Net (decrease) increase in cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Contingent consideration Business Combination, Contingent Consideration, Range of Outcomes, Maximum, Amount Research and development Research and Development Expense (Excluding Acquired in Process Cost) Deferred tax liabilities, net Business Combination, Recognized Liability Assumed, Deferred Tax Liability Net income Net income Net income Net Income (Loss) Attributable to Parent Long-term Debt, Type [Axis] Long-Term Debt, Type [Axis] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Restatement Determination Date: Restatement Determination Date [Axis] Schedule of Accumulated Other Comprehensive Income (Loss) Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block] Japan JAPAN Recognized in other comprehensive income (loss) Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), before Reclassification and Tax Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] Derivative Instruments and Hedging Activities Disclosure [Abstract]