Significant agreements - Ionis Agreements (Details) - USD ($) $ in Thousands |
1 Months Ended | 3 Months Ended | 9 Months Ended | |||||
|---|---|---|---|---|---|---|---|---|
Jul. 31, 2025 |
Sep. 30, 2026 |
Sep. 30, 2025 |
Sep. 30, 2026 |
Sep. 30, 2025 |
Dec. 31, 2025 |
Jun. 30, 2025 |
Dec. 31, 2024 |
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| Significant agreements. | ||||||||
| Revenue from collaborative arrangement | $ 34,057 | $ 11,734 | $ 35,573 | $ 24,631 | ||||
| Deferred revenue | 3,692 | 3,692 | $ 38,469 | $ 101,658 | ||||
| Ionis | ||||||||
| Significant agreements. | ||||||||
| Revenue from collaborative arrangement | 0 | $ 2,000 | 0 | $ 2,000 | ||||
| Deferred revenue | $ 3,692 | $ 3,692 | $ 3,840 | $ 3,587 | ||||
| Payment received | $ 2,000 | |||||||
| Transaction price | $ 39,800 | $ 37,800 | ||||||
| Ionis | Minimum | ||||||||
| Significant agreements. | ||||||||
| Material rights exercise period | 4 years | |||||||
| Ionis | Maximum | ||||||||
| Significant agreements. | ||||||||
| Material rights exercise period | 7 years | |||||||
| X | ||||||||||
- Definition Payment received from collaborative arrangement. No definition available.
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| X | ||||||||||
- Definition The duration of material rights exercised or expired. No definition available.
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- Definition Amount of allocated determined transaction price under revenue recognition arrangement. No definition available.
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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