v3.26.3
Significant agreements (Tables)
9 Months Ended
Sep. 30, 2026
Significant agreements  
Summary of revenue recognized from collaboration arrangements The following table summarizes the revenue recognized in the Company’s condensed consolidated statements of operations and comprehensive loss from these arrangements (in thousands):

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Three Months 

​

Nine Months

​

​

Ended 

​

Ended 

​

​

September 30, 

​

September 30, 

​

  ​ ​ ​

2026

  ​ ​ ​

2025

  ​ ​ ​

2026

  ​ ​ ​

2025

Collaboration revenue

  ​ ​ ​

  ​

​

  ​ ​ ​

  ​

​

  ​ ​ ​

  ​

​

  ​ ​ ​

  ​

​

Bayer

​

$

34,057

​

$

1,016

​

$

35,573

​

$

2,873

Novartis

​

​

—

​

​

2,181

​

​

—

​

​

5,077

Ionis

​

​

—

​

​

2,000

​

​

—

​

​

2,000

Genentech

​

​

—

​

​

6,537

​

​

—

​

​

14,681

Total collaboration revenue

​

$

34,057

​

$

11,734

​

$

35,573

​

$

24,631

Summary of changes in the balances of the Company's contract assets and liabilities

The following table presents changes in the balances of the Company’s contract liabilities (in thousands):

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Beginning Balance

​

​

​

​

​

Impact of

​

Ending Balance

​

​

January 1,

​

​

​

​

​

Exchange

​

September 30,

​

  ​ ​ ​

2026

  ​ ​ ​

Additions

  ​ ​ ​

Deductions

  ​ ​ ​

Rates

  ​ ​ ​

2026

Contract liabilities:

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

Deferred revenue

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

Bayer collaboration deferred revenue

​

$

34,629

​

$

969

​

$

(35,573)

​

$

(25)

​

$

—

Ionis collaboration deferred revenue

​

​

3,840

​

​

—

​

​

—

​

​

(148)

​

​

3,692

Total deferred revenue

​

$

38,469

​

$

969

​

$

(35,573)

​

$

(173)

​

$

3,692

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Beginning Balance

​

​

​

 

​

Impact of

​

Ending Balance

​

​

January 1,

​

​

​

​

​

Exchange

​

December 31,

​

  ​ ​ ​

2025

  ​ ​ ​

Additions

  ​ ​ ​

Deductions

  ​ ​ ​

Rates

  ​ ​ ​

2025

Contract liabilities:

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

Deferred revenue

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

​

Bayer collaboration deferred revenue

​

$

39,960

​

$

960

​

$

(8,920)

​

$

2,629

​

$

34,629

Novartis collaboration deferred revenue

​

​

44,073

​

​

—

​

​

(46,985)

​

​

2,912

​

​

—

Ionis collaboration deferred revenue

​

​

3,587

​

​

—

​

​

—

​

​

253

​

​

3,840

Genentech collaboration deferred revenue

​

​

14,038

​

​

—

​

​

(14,681)

​

​

643

​

​

—

Total deferred revenue

​

$

101,658

​

$

960

​

$

(70,586)

​

$

6,437

​

$

38,469

Summary of recognition of revenues as a result of changes in contract asset and contract liability balances

During the three and nine months ended September 30, 2026 and 2025, the Company recognized the following revenue as a result of changes in the contract asset and the contract liability balances in the respective periods (in thousands):

​

​

​

​

​

​

​

​

​

​

​

​

​

Three Months Ended

​

Nine Months Ended

​

September 30, 

​

September 30, 

​

2026

  ​ ​ ​

2025

​

2026

  ​ ​ ​

2025

Revenue recognized in the period from:

​

  ​

​

​

  ​

​

​

  ​

​

​

  ​

Revenue recognized based on proportional performance

$

—

​

$

3,197

​

$

1,516

​

$

8,581

Revenue recognized based on contract modifications and expiration of material rights

​

34,057

 

​

6,537

​

​

34,057

 

​

14,050

Revenue recognized based on changes in transaction price

​

—

​

​

2,000

​

​

—

​

​

2,000

Total

$

34,057

​

$

11,734

​

$

35,573

​

$

24,631

​