<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:01a01947-18dc-7cb6-971c-8725ae7ad592,g:0e33c631-84dd-4a8d-8008-f8df5a0275db-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.novocure.com/role/DocumentandEntityInformationDocument" xlink:type="simple" xlink:href="nvcr-20261029.xsd#DocumentandEntityInformationDocument"/>
  <link:presentationLink xlink:role="http://www.novocure.com/role/DocumentandEntityInformationDocument" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_01a01947-18dc-7ce0-b446-4d12fdf59b65" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_DocumentType_01a01947-18dc-7ce0-b446-4d12fdf59b65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_01a01947-18dc-76e8-be82-cf62b9fa6144" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_DocumentPeriodEndDate_01a01947-18dc-76e8-be82-cf62b9fa6144" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_01a01947-18dc-74f4-b963-d4aaae20f87f" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityRegistrantName_01a01947-18dc-74f4-b963-d4aaae20f87f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_01a01947-18dc-72ed-afd8-844e2ca205ca" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityCentralIndexKey_01a01947-18dc-72ed-afd8-844e2ca205ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_01a01947-18dc-79a5-b988-5297aa2d9d0c" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_AmendmentFlag_01a01947-18dc-79a5-b988-5297aa2d9d0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_01a01947-18dc-7b96-86ac-509c5bc57688" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityIncorporationStateCountryCode_01a01947-18dc-7b96-86ac-509c5bc57688" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_01a01947-18dc-74a9-96d0-f83f7a8f0439" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityFileNumber_01a01947-18dc-74a9-96d0-f83f7a8f0439" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_01a01947-18dc-7ccc-ab50-04c07533d002" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityTaxIdentificationNumber_01a01947-18dc-7ccc-ab50-04c07533d002" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_01a01947-18dc-7d7c-ae53-c7771fbb9b8b" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityAddressAddressLine1_01a01947-18dc-7d7c-ae53-c7771fbb9b8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_01a01947-18dc-7572-bcc6-78f848731c48" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityAddressCityOrTown_01a01947-18dc-7572-bcc6-78f848731c48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCountry_01a01947-18dc-74c9-8703-61e97252fc7b" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressCountry"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityAddressCountry_01a01947-18dc-74c9-8703-61e97252fc7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_01a01947-18dc-76e2-b234-93bcbb70be5a" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityAddressPostalZipCode_01a01947-18dc-76e2-b234-93bcbb70be5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_01a01947-18dc-7677-a23b-242801ef625f" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_CityAreaCode_01a01947-18dc-7677-a23b-242801ef625f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_01a01947-18dc-74be-b405-227798288c92" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_LocalPhoneNumber_01a01947-18dc-74be-b405-227798288c92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_01a01947-18dc-78be-b389-70dc35845e9b" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_WrittenCommunications_01a01947-18dc-78be-b389-70dc35845e9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_01a01947-18dc-7ed1-862c-bb128945b137" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_SolicitingMaterial_01a01947-18dc-7ed1-862c-bb128945b137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_01a01947-18dc-7ed7-a75c-908d0c64e861" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_PreCommencementTenderOffer_01a01947-18dc-7ed7-a75c-908d0c64e861" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_01a01947-18dc-707d-ae57-494d91da7f50" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_01a01947-18dc-707d-ae57-494d91da7f50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_01a01947-18dc-7d90-bdbd-19962116ecb8" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_Security12bTitle_01a01947-18dc-7d90-bdbd-19962116ecb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_01a01947-18dc-73bd-8ce4-6a1a50035ee1" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_TradingSymbol_01a01947-18dc-73bd-8ce4-6a1a50035ee1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_01a01947-18dc-767c-ab17-071205cfe7d6" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_SecurityExchangeName_01a01947-18dc-767c-ab17-071205cfe7d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_01a01947-18dc-75e3-b61e-868f7204bf3a" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_01a01947-18dc-7f65-8aae-b1c2f4fa94fe" xlink:to="loc_dei_EntityEmergingGrowthCompany_01a01947-18dc-75e3-b61e-868f7204bf3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
