v3.26.3
Shareholders' Equity (Tables)
 9 Months Ended
Sep. 30, 2026
Stockholders' Equity Note [Abstract]  
Schedule of changes in shareholders' equity (deficit)
Changes in shareholders’ equity for the three and nine months ended September 30, 2026 and 2025 were as follows:
Common Shares
SharesAmountAdditional Paid-in CapitalAccumulated Deficit
Accumulated Other Comprehensive Income (Loss)
Total Shareholders' Equity (Deficit)
Balances as of December 31, 2025132,775,113 $1,934,276 $193,984 $(2,084,536)$8,348 $52,072 
Net loss— — — (130,532)— (130,532)
Issuance of common shares, net of offering costs17,164,940 178,884 — — — 178,884 
Issuance of common shares as payment under license and other agreements76,383 858 — — — 858 
Issuance of common shares under 2022 Equity Incentive Plan490,054 18,890 (18,912)— — (22)
Non-cash share-based compensation expense— — 28,286 — — 28,286 
Other comprehensive loss— — — — (46)(46)
Balances as of March 31, 2026150,506,490 $2,132,908 $203,358 $(2,215,068)$8,302 $129,500 
Net loss— — — (137,311)— (137,311)
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan511,041 5,953 (2,157)— — 3,796 
Non-cash share-based compensation expense— — 19,164 — — 19,164 
Other comprehensive loss— — — — (2,927)(2,927)
Balances as of June 30, 2026151,017,531 $2,138,861 $220,365 $(2,352,379)$5,375 $12,222 
Net loss— — — (129,279)— (129,279)
Issuance of common shares under 2022 Equity Incentive Plan37,629 365 (154)— — 211 
Non-cash share-based compensation expense— — 18,624 — — 18,624 
Other comprehensive loss— — — — (25)(25)
Balances as of September 30, 2026151,055,160 $2,139,226 $238,835 $(2,481,658)$5,350 $(98,247)
Common Shares
SharesAmountAdditional Paid-in CapitalAccumulated Deficit
Accumulated Other Comprehensive Income (Loss)
Total Shareholders' Equity
Balances as of December 31, 2024101,221,989 $1,656,702 $112,369 $(1,345,714)$79 $423,436 
Net loss— — — (221,677)— (221,677)
Issuance of common shares as payment under license and other agreements354,819 13,398 (8,554)— — 4,844 
Issuance of common shares under 2022 Equity Incentive Plan
527,216 19,246 (19,410)— — (164)
Non-cash share-based compensation expense— — 53,062 — — 53,062 
Other comprehensive loss— — — — (6)(6)
Balances as of March 31, 2025102,104,024 $1,689,346 $137,467 $(1,567,391)$73 $259,495 
Net loss— — — (198,147)— (198,147)
Issuance of common shares as payment under license and other agreements
3,588,688 51,426 — — — 51,426 
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan89,735 2,337 (1,260)— — 1,077 
Non-cash share-based compensation expense— — 20,812 — — 20,812 
Other comprehensive loss— — — — (76)(76)
Balances as of June 30, 2025105,782,447 $1,743,109 $157,019 $(1,765,538)$(3)$134,587 
Net loss
— — — (173,443)— (173,443)
Issuance of common shares under 2022 Equity Incentive Plan21,208 631 (509)— — 122 
Non-cash share-based compensation expense— — 21,535 — — 21,535 
Other comprehensive income— — — — 39 39 
Balances as of September 30, 2025105,803,655 $1,743,740 $178,045 $(1,938,981)$36 $(17,160)