v3.26.3
Segment Reporting - Schedule of Segment Reporting Presents Reportable Segment Profit and Loss (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2026
Sep. 30, 2025
Sep. 30, 2026
Sep. 30, 2025
Revenue $ 0 $ 2,764 $ 99,365 $ 36,341
Less:        
Research and development 128,509 74,094 346,152 232,737
External research and development [1] 31,023 21,950 88,051 71,634
Research and development compensation and related personnel expense [2] 30,346 22,323 86,187 66,330
Research and development overhead and administrative costs 15,126 12,468 41,016 34,622
General and administrative [3] 18,723 17,336 60,207 51,252
Interest and other expense [4] 62 3,953 203 4,135
Plus: [Abstract]        
Interest income 15,295 10,444 44,753 27,413
Segment net loss (131,999) (82,175) (262,444) (224,370)
STAT6 [Member]        
Less:        
Research and development $ 52,014 $ 17,353 $ 130,898 $ 60,151
[1] Certain prior period amounts have been recast to conform with current period presentation.
[2] Research and development compensation and related personnel expense for the three months ended September 30, 2026 and 2025 is inclusive of $10.9 and $8.4 million of stock-based compensation expense, respectively. Research and development compensation and related personnel expense for the nine months ended September 30, 2026 and 2025 is inclusive of $29.9 million and $23.9 million of stock-based compensation expense, respectively.
[3] General and administrative expense for the three months ended September 30, 2026 and 2025 is inclusive of $7.9 million and $7.4 million of stock-based compensation expense, respectively. General and administrative expense for the nine months ended September 30, 2026 and 2025 is inclusive of $23.9 million and $21.5 million of stock-based compensation expense, respectively.
[4] Other expense for the three and nine months ended September 30, 2025 is inclusive of a $3.9 million impairment of long-lived assets.