Collaborative and Other Relationships - Ionis Pharmaceuticals, Inc (Details) - USD ($) $ in Millions |
3 Months Ended | 9 Months Ended | ||
|---|---|---|---|---|
Sep. 30, 2026 |
Sep. 30, 2025 |
Sep. 30, 2026 |
Sep. 30, 2025 |
|
| Collaborative arrangements and non-collaborative arrangement transactions | ||||
| Research and development: | $ 574.0 | $ 436.1 | $ 1,642.6 | $ 1,269.2 |
| Ionis | ||||
| Collaborative arrangements and non-collaborative arrangement transactions | ||||
| Research and development: | 7.5 | 15.0 | ||
| Estimated additional payments upon achievement of development and commercial milestones | 110.0 | 110.0 | ||
| Estimated additional payments upon initiation of new phases | 45.0 | 45.0 | ||
| Expected additional milestone payments when meeting certain sales threshold | $ 400.0 | $ 400.0 | ||