The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 6,166,076 68,239 SH SOLE 68,239 0 0
3D SYS CORP DEL COM NEW 88554D205 37,966 10,546 SH SOLE 10,546 0 0
ABBOTT LABORATORIES COM 002824100 334,737 3,387 SH SOLE 3,387 0 0
ABBVIE INC COM 00287Y109 16,810,297 64,262 SH SOLE 64,262 0 0
ABEONA THERAPEUTICS INC COM NEW 00289Y206 1,450,748 276,333 SH SOLE 276,333 0 0
ACHIEVE LIFE SCIENCE INC COM 004468500 7,540,729 932,105 SH SOLE 932,105 0 0
AGILON HEALTH INC COM NEW 00857U206 669,034 8,406 SH SOLE 8,406 0 0
AGNC INVT CORP COM 00123Q104 431,750 47,602 SH SOLE 47,602 0 0
AMGEN INC COM 031162100 8,816,725 20,917 SH SOLE 20,917 0 0
ANNALY CAPITAL MANAGEMENT IN COM NEW 035710839 518,474 27,447 SH SOLE 27,447 0 0
AQUESTIVE THERAPEUTICS INC COM 03843E104 1,290,487 278,723 SH SOLE 278,723 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 22,884,733 865,862 SH SOLE 865,862 0 0
ARMOUR RESIDENTIAL REIT INC COM SHS 042315705 551,139 39,851 SH SOLE 39,851 0 0
ARTIVA BIOTHERAPEUTICS INC COM 04317A107 721,648 101,355 SH SOLE 101,355 0 0
AVANTOR INC COM 05352A100 14,537,081 965,919 SH SOLE 965,919 0 0
BENITEC BIOPHARMA INC COM NEW 08205P209 10,022,010 1,002,201 SH SOLE 1,002,201 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 486,497 977 SH SOLE 977 0 0
BIOHAVEN LTD COM G1110E107 7,351,752 550,693 SH SOLE 550,693 0 0
BRAEMAR HOTELS & RESORTS INC COM 10482B101 1,090,510 653,000 SH SOLE 653,000 0 0
CABALETTA BIO INC COM 12674W109 1,067,971 556,235 SH SOLE 556,235 0 0
CARDINAL HEALTH INC COM 14149Y108 5,955,836 26,830 SH SOLE 26,830 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 700,996 21,629 SH SOLE 21,629 0 0
CISCO SYS INC COM 17275R102 698,949 6,494 SH SOLE 6,494 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 2,040,628 93,521 SH SOLE 93,521 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 1,124,340 90,381 SH SOLE 90,381 0 0
COOPER COS INC COM 216648501 743,143 13,146 SH SOLE 13,146 0 0
CORCEPT THERAPEUTICS INC COM 218352102 2,370,051 20,568 SH SOLE 20,568 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 288,000 25,000 SH SOLE 25,000 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 406,391 1,535 SH SOLE 1,535 0 0
CVS HEALTH CORP COM 126650100 5,992,559 69,933 SH SOLE 69,933 0 0
DANAHER CORP DEL COM 235851102 2,105,833 9,505 SH SOLE 9,505 0 0
DELCATH SYS INC COM NEW 24661P807 3,636,034 227,679 SH SOLE 227,679 0 0
DELL TECHNOLOGIES INC CL C 24703L202 551,937 1,026 SH SOLE 1,026 0 0
DYNEX CAP INC COM 26817Q886 567,182 50,914 SH SOLE 50,914 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 1,607,019 18,617 SH SOLE 18,617 0 0
ELEVANCE HEALTH INC FORMERLY COM 036752103 2,844,607 7,316 SH SOLE 7,316 0 0
ELI LILLY & CO COM 532457108 34,814,223 30,088 SH SOLE 30,088 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 3,871,569 60,333 SH SOLE 60,333 0 0
EXXONMOBIL HOLDINGS CORP COM SHS 30233Q108 286,440 1,760 SH SOLE 1,760 0 0
FLUOR CORP COM 343412102 297,622 6,216 SH SOLE 6,216 0 0
FULCRUM THERAPEUTICS INC COM 359616109 567,173 153,290 SH SOLE 153,290 0 0
FULL HSE RESORTS INC COM 359678109 862,650 607,500 SH SOLE 607,500 0 0
GE AEROSPACE COM NEW 369604301 203,301 651 SH SOLE 651 0 0
GE HEALTHCARE TECHNOLOGIES I COMMON STOCK 36266G107 3,391,199 51,877 SH SOLE 51,877 0 0
GILEAD SCIENCES INC COM 375558103 12,082,142 81,061 SH SOLE 81,061 0 0
GRAIL INC COM 384747101 6,020,816 42,969 SH SOLE 42,969 0 0
GUARDANT HEALTH INC COM 40131M109 8,728,938 48,940 SH SOLE 48,940 0 0
HUMANA INC COM 444859102 24,874,548 65,190 SH SOLE 65,190 0 0
ICON PUB LTD CO SHS G4705A100 254,135 1,495 SH SOLE 1,495 0 0
IMMUNIC INC COM NEW 4525EP200 285,742 30,725 SH SOLE 30,725 0 0
INSMED INC COM PAR $.01 457669307 1,586,318 13,898 SH SOLE 13,898 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 326,376 1,484 SH SOLE 1,484 0 0
INVENTIVA SA ADS 46124U107 1,156,752 313,483 SH SOLE 313,483 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 2,219,310 3,000 SH Call SOLE 3,000 0 0
ISHARES BITCOIN TRUST ETF SHS BEN INT 46438F101 16,914,582 357,300 SH SOLE 357,300 0 0
ISHARES BITCOIN TRUST ETF SHS BEN INT 46438F101 111,850,218 2,362,700 SH Call SOLE 2,362,700 0 0
ISHARES BITCOIN TRUST ETF SHS BEN INT 46438F101 18,936,000 400,000 SH Put SOLE 400,000 0 0
ISHARES TR CORE S&P500 ETF 464287200 780,088,683 1,018,592 SH SOLE 1,018,592 0 0
ISHARES TR CORE US AGGBD ET 464287226 445,288,978 4,710,059 SH SOLE 4,710,059 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 12,453,461 53,790 SH SOLE 53,790 0 0
JOHNSON & JOHNSON COM 478160104 16,534,866 62,457 SH SOLE 62,457 0 0
KYVERNA THERAPEUTICS INC COM 501976104 1,241,700 182,603 SH SOLE 182,603 0 0
LEONABIO INC COM 04746L203 532,926 149,279 SH SOLE 149,279 0 0
MASTERCARD INCORPORATED CL A 57636Q104 297,794 540 SH SOLE 540 0 0
MFA FINL INC COM 55272X607 516,318 65,773 SH SOLE 65,773 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 2,899,557 3,349,379 SH SOLE 3,349,379 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 468,923 3,306 SH SOLE 3,306 0 0
OCULAR THERAPEUTIX INC COM 67576A100 621,661 81,051 SH SOLE 81,051 0 0
ORCHESTRA BIOMED HLDGS INC COM 68572M106 1,364,587 219,387 SH SOLE 219,387 0 0
PACIRA BIOSCIENCES INC COM 695127100 2,074,491 82,814 SH SOLE 82,814 0 0
PALANTIR TECHNOLOGIES INC CL A 69608A108 788,790 4,217 SH SOLE 4,217 0 0
PALISADE BIO INC COM 696389402 586,350 434,333 SH SOLE 434,333 0 0
PENNYMAC MTG INVT TR COM 70931T103 374,300 47,500 SH SOLE 47,500 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 1,819,649 249,267 SH SOLE 249,267 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207 32,954,124 1,272,360 SH SOLE 1,272,360 0 0
PROKIDNEY CORP SHS CL A 74291D104 803,010 483,741 SH SOLE 483,741 0 0
PURECYCLE TECHNOLOGIES INC COM 74623V103 14,668,785 3,326,255 SH SOLE 3,326,255 0 0
QUALCOMM INC COM 747525103 289,495 1,573 SH SOLE 1,573 0 0
QUEST DIAGNOSTICS INC COM 74834L100 11,545,822 49,538 SH SOLE 49,538 0 0
RITHM CAPITAL CORP COM NEW 64828T201 2,341,022 269,703 SH SOLE 269,703 0 0
SAB BIOTHERAPEUTICS INC COM NEW 78397T202 332,371 104,849 SH SOLE 104,849 0 0
SALESFORCE INC COM 79466L302 324,612 1,414 SH SOLE 1,414 0 0
SCHEIN HENRY INC COM 806407102 3,190,776 37,999 SH SOLE 37,999 0 0
SEAGATE TECHNOLOGY HLDNGS PL ORD SHS G7997R103 363,402 394 SH SOLE 394 0 0
SERVICENOW INC COM 81762P102 236,126 1,762 SH SOLE 1,762 0 0
SIMPLIFY EXCHANGE TRADED FUN PIPE SAND SM ETF 82889N327 3,015,541 91,464 SH SOLE 91,464 0 0
SIMPLIFY EXCHANGE TRADED FUN US EQUI PLUS ETF 82889N228 44,010,000 1,500,000 SH SOLE 1,500,000 0 0
SIMPLIFY EXCHANGE TRADED FUN ANCORATO TARGET 82889N343 2,676,005 116,500 SH SOLE 116,500 0 0
SIMPLIFY EXCHANGE TRADED FUN MULTI QIS ALTERN 82889N533 48,129,042 4,477,620 SH SOLE 4,477,620 0 0
SIMPLIFY EXCHANGE TRADED FUN TAXAWARE DIV INC 82889N186 1,828,875 75,000 SH SOLE 75,000 0 0
SIMPLIFY EXCHANGE TRADED FUN US EQUITY INCOME 82889N301 27,150,882 559,812 SH SOLE 559,812 0 0
SIMPLIFY EXCHANGE TRADED FUN CHINA A SHS PLUS 82889N384 10,020,236 428,078 SH SOLE 428,078 0 0
SIMPLIFY EXCHANGE TRADED FUN GOVT MONE MA ETF 82889N269 3,977,208,694 39,748,238 SH SOLE 39,748,238 0 0
SIMPLIFY EXCHANGE TRADED FUN TARGE 15 ETF 82889N350 27,700,685 1,149,406 SH SOLE 1,149,406 0 0
SIMPLIFY EXCHANGE TRADED FUN SHORT TERM TREA 82889N657 452,010 23,740 SH SOLE 23,740 0 0
SIMPLIFY EXCHANGE TRADED FUN NEXT INTANGIBLE 82889N475 3,494,744 97,303 SH SOLE 97,303 0 0
SIMPLIFY EXCHANGE TRADED FUN TREASURY OPT INC 82889N640 22,503,000 975,000 SH SOLE 975,000 0 0
SIMPLIFY EXCHANGE TRADED FUN NATL MUNI BD ETF 82889N442 35,906,286 1,553,376 SH SOLE 1,553,376 0 0
SIMPLIFY EXCHANGE TRADED FUN AGGREGATE BD ETF 82889N723 12,325,834 651,127 SH SOLE 651,127 0 0
SNOWFLAKE INC COM SHS 833445109 217,658 641 SH SOLE 641 0 0
SPDR GOLD TR GOLD SHS 78463V107 89,535,484 235,100 SH Call SOLE 235,100 0 0
STRYKER CORPORATION COM 863667101 617,975 2,244 SH SOLE 2,244 0 0
SUMMIT THERAPEUTICS INC COM 86627T108 8,625,892 510,106 SH SOLE 510,106 0 0
TESLA INC COM 88160R101 3,606,644 10,165 SH SOLE 10,165 0 0
TG THERAPEUTICS INC COM 88322Q108 1,183,150 21,211 SH SOLE 21,211 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 16,288,956 24,130 SH SOLE 24,130 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 8,715,759 16,084 SH SOLE 16,084 0 0
UNITEDHEALTH GROUP INC COM 91324P102 15,198,213 41,403 SH SOLE 41,403 0 0
UPSTREAM BIO INC COM 91678A107 327,336 62,113 SH SOLE 62,113 0 0
VANECK BITCOIN ETF SH BEN INT 92189K105 4,153,412 175,843 SH SOLE 175,843 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 5,451,863 10,428 SH SOLE 10,428 0 0
WALMART INC COM 931142103 660,516 6,356 SH SOLE 6,356 0 0
WARBY PARKER INC CL A COM 93403J106 17,427,422 627,337 SH SOLE 627,337 0 0
WESTERN DIGITAL CORP COM 958102105 295,399 650 SH SOLE 650 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 389,342 4,383 SH SOLE 4,383 0 0