| Schedule of Segment Reporting |
The following table represents information provided to the CODM: | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2026 | | 2025 | | 2026 | | 2025 | | Research and development expenses: | | | | | | | | | Wages and benefits | $ | 3,558 | | | $ | 1,940 | | | $ | 9,383 | | | $ | 5,200 | | | Tibulizumab SSc program | 2,741 | | | 3,054 | | | 10,149 | | | 7,251 | | | Tibulizumab HS program | 3,913 | | | 2,657 | | | 13,302 | | | 5,931 | | | Tibulizumab PMR program | 2,161 | | | — | | | 2,665 | | | — | | | Tibulizumab program general | 5,025 | | | 2,726 | | | 14,379 | | | 8,597 | | | Additional product candidates (torudokimab and crebankitug) | 265 | | | 481 | | | 615 | | | 1,231 | | | Unallocated research and development expenses | 596 | | | 521 | | | 1,636 | | | 1,454 | | | General and administrative expenses: | | | | | | | | | Wages and benefits | 2,257 | | | 2,450 | | | 6,936 | | | 7,832 | | | Other general and administrative expenses | 2,921 | | | 3,299 | | | 9,694 | | | 9,550 | | | Share-based compensation | 5,316 | | | 2,379 | | | 14,781 | | | 9,755 | | | Other segment items* | (2,928) | | | (1,467) | | | (7,188) | | | (5,326) | | | Net loss | $ | 25,825 | | | $ | 18,040 | | | $ | 76,352 | | | $ | 51,475 | |
*Other segment items include depreciation and amortization, income tax benefit, interest income, and other income, net.
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| Schedule of Potentially Dilutive Securities Not Included in Calculation of Diluted Net Loss Per Share because to do so would be Anti-dilutive |
The table below provides potentially dilutive securities not included in the calculation of the diluted net loss per share as of the periods presented because to do so would be anti-dilutive: | | | | | | | | | | | | | September 30, | | 2026 | | 2025 | | Shares issuable upon exercise of options to purchase Class A Ordinary Shares | 18,508,116 | | | 14,480,663 | | | Shares issuable upon exercise of Z33 Series Seed Preferred Shares Put Right | — | | | 2,000,000 | | | Shares issuable upon vesting of restricted share units | 256,642 | | | 573,282 | | | Restricted share awards | 124,999 | | | 249,997 | | | Total | 18,889,757 | | | 17,303,942 | |
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