| Schedule of selected financial information with respect to the company's single operating segment |
| | | | | | | | | | | | | | | Three Months Ended | | Nine Months Ended | | | September 30, | | September 30, | | | 2026 | | 2025 | | 2026 | | 2025 | Revenue: | | | | | | | | | | | | | Product revenue, net | | $ | 285,970 | | $ | 180,855 | | $ | 743,836 | | $ | 475,437 | License and collaboration revenue | | | - | | | - | | | - | | | - | Total revenue | | | 285,970 | | | 180,855 | | | 743,836 | | | 475,437 | Operating expenses: | | | | | | | | | | | | | Cost of goods sold | | | 27,759 | | | 20,257 | | | 72,127 | | | 56,728 | Collaboration expenses | | | 105,828 | | | 63,307 | | | 269,474 | | | 159,515 | Direct research and development expenses by program: | | | | | | | | | | | | | ARCALYST | | | 176 | | | 269 | | | 849 | | | 795 | KPL-387 | | | 17,250 | | | 11,380 | | | 54,844 | | | 25,043 | KPL-1161 | | | 1,621 | | | 1,792 | | | 3,342 | | | 2,262 | Abiprubart | | | 77 | | | 708 | | | 306 | | | 5,710 | Unallocated research and development expenses | | | 13,662 | | | 10,017 | | | 41,819 | | | 28,434 | Selling, general and administrative | | | 65,361 | | | 49,104 | | | 190,378 | | | 139,497 | Total operating expenses | | | 231,734 | | | 156,834 | | | 633,139 | | | 417,984 | Other income, net (1) | | | 4,821 | | | 3,136 | | | 12,186 | | | 8,146 | Income before income taxes | | | 59,057 | | | 27,157 | | | 122,883 | | | 65,599 | Provision for income taxes | | | (11,712) | | | (8,722) | | | (27,514) | | | (20,793) | Net income | | $ | 47,345 | | $ | 18,435 | | $ | 95,369 | | $ | 44,806 | | | | | | | | | | | | | | Other significant noncash items: | | | | | | | | | | | | | Share-based compensation expense | | $ | 13,065 | | $ | 10,144 | | $ | 34,757 | | $ | 26,768 | Non-cash lease expense | | | 1,005 | | | 944 | | | 3,010 | | | 2,703 | Deferred income taxes | | | (6,565) | | | 4,227 | | | 619 | | | 9,864 |
|
| Schedule of total revenue by geographic region of the customer |
| | | | | | | | | | | | | | | Three Months Ended | | Nine Months Ended | | | September 30, | | September 30, | | | 2026 | | 2025 | | 2026 | | 2025 | Revenue: | | | | | | | | | | | | | United States | | $ | 285,727 | | $ | 180,709 | | $ | 742,911 | | $ | 474,811 | United Kingdom | | | 243 | | | 146 | | | 925 | | | 626 | Total revenue | | $ | 285,970 | | $ | 180,855 | | $ | 743,836 | | $ | 475,437 |
|