v3.26.3
Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive (Loss) Income
Beginning balance at Dec. 31, 2024 $ 1,157,847 $ 54 $ 4,515,879 $ (3,358,514) $ 428
Beginning balance, Shares at Dec. 31, 2024   542,549      
Exercise of stock options and employee stock purchase plan, Shares   13,178      
Exercise of stock options and employee stock purchase plan, value 23,645 $ 2 23,643    
Shares issued upon vesting of restricted stock units, shares   15,927      
Shares issued upon vesting of restricted stock units, value 20,265 $ 1 20,264    
Shares issued under At-the-Market Offering, net of issuance costs, Shares   29,494      
Shares issued under At-the-Market Offering, net of issuance costs, value 264,176 $ 3 264,173    
Stock-based compensation 84,645   84,645    
Net loss (334,945)     (334,945)  
Unrealized gain (loss) on marketable securities 115       115
Ending balance at Sep. 30, 2025 1,215,748 $ 60 4,908,604 (3,693,459) 543
Ending balance, Shares at Sep. 30, 2025   601,148      
Beginning balance at Jun. 30, 2025 1,024,796 $ 56 4,612,488 (3,587,635) (113)
Beginning balance, Shares at Jun. 30, 2025   565,316      
Exercise of stock options and employee stock purchase plan, Shares   3,218      
Exercise of stock options and employee stock purchase plan, value 7,986 $ 1 7,985    
Shares issued upon vesting of restricted stock units, shares   3,326      
Shares issued upon vesting of restricted stock units, value 25   25    
Shares issued under At-the-Market Offering, net of issuance costs, Shares   29,288      
Shares issued under At-the-Market Offering, net of issuance costs, value 263,269 $ 3 263,266    
Stock-based compensation 24,840   24,840    
Net loss (105,824)     (105,824)  
Unrealized gain (loss) on marketable securities 656       656
Ending balance at Sep. 30, 2025 1,215,748 $ 60 4,908,604 (3,693,459) 543
Ending balance, Shares at Sep. 30, 2025   601,148      
Beginning balance at Dec. 31, 2025 1,168,973 $ 61 4,961,832 (3,793,564) 644
Beginning balance, Shares at Dec. 31, 2025   607,630      
Exercise of stock options and employee stock purchase plan, Shares   829      
Exercise of stock options and employee stock purchase plan, value 3,715   3,715    
Shares issued upon vesting of restricted stock units, shares   13,600      
Shares issued upon vesting of restricted stock units, value 16,742 $ 1 16,741    
Stock-based compensation 63,307   63,307    
Capital contribution under collaboration agreement - related party 28,856   28,856    
Net loss (283,516)     (283,516)  
Unrealized gain (loss) on marketable securities (2,733)       (2,733)
Ending balance at Sep. 30, 2026 995,344 $ 62 5,074,451 (4,077,080) (2,089)
Ending balance, Shares at Sep. 30, 2026   622,059      
Beginning balance at Jun. 30, 2026 1,047,972 $ 62 5,041,507 (3,992,603) (994)
Beginning balance, Shares at Jun. 30, 2026   619,109      
Exercise of stock options and employee stock purchase plan, Shares   69      
Exercise of stock options and employee stock purchase plan, value 108   108    
Shares issued upon vesting of restricted stock units, shares   2,881      
Stock-based compensation 14,333   14,333    
Capital contribution under collaboration agreement - related party 18,503   18,503    
Net loss (84,477)     (84,477)  
Unrealized gain (loss) on marketable securities (1,095)       (1,095)
Ending balance at Sep. 30, 2026 $ 995,344 $ 62 $ 5,074,451 $ (4,077,080) $ (2,089)
Ending balance, Shares at Sep. 30, 2026   622,059