Exhibit 2.1

Annex A-2

AMENDMENT TO BUSINESS COMBINATION AGREEMENT AND COMPANY DISCLOSURE LETTER

This AMENDMENT, dated as of October 22, 2026 (this “Amendment”), to the BUSINESS COMBINATION AGREEMENT and the COMPANY DISCLOSURE LETTER is made and entered into by and among Inflection Point Acquisition Corp. VI, a Cayman Islands exempted company (which shall transfer by way of continuation to and domesticate as a Delaware corporation prior to the Closing) (the “Purchaser”), IPFX PubCo, Inc., a Delaware corporation and wholly owned subsidiary of the Purchaser (“Pubco”), IPFX Merger Sub, Inc., a Delaware corporation and direct, wholly owned subsidiary of Pubco (“Merger Sub”), and Quantum Space, LLC, a Delaware limited liability company (the “Company”). The Purchaser, Pubco, Merger Sub and the Company are sometimes referred to herein individually as a “Party” and, collectively, as the “Parties.”

RECITALS:

WHEREAS, the Parties are parties to that certain Business Combination Agreement, dated as of June 8, 2026 (as may be further amended or supplemented from time to time, the “Business Combination Agreement”);

WHEREAS, in connection with the Business Combination Agreement, the Company delivered to the Purchaser, Pubco and Merger Sub (collectively, the “Purchaser Parties”) that certain Company Disclosure Letter, dated as of June 8, 2026 (the “Company Disclosure Letter”), which, pursuant to Section 10.17 of the Business Combination Agreement, is a part of the Business Combination Agreement as if fully set forth therein;

WHEREAS, the Business Combination Agreement currently contemplates that, from and after the Closing, the Pubco Class A-1 Common Stock and the Pubco Warrants will be listed on Nasdaq, and the Parties now desire that such securities instead be listed on the New York Stock Exchange;

WHEREAS, pursuant to Section 10.11 of the Business Combination Agreement, the Business Combination Agreement may be amended, supplemented or modified only by execution of a written instrument signed by the Purchaser Parties and the Company; and

WHEREAS, the Parties desire to amend the Business Combination Agreement as hereinafter set forth, including to amend the Company Disclosure Letter to replace Annex 3.03(a) thereto in its entirety.

NOW, THEREFORE for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties hereby agree as follows:

“(ii) from and after the Closing, the Parties intend to list on the NYSE only the Pubco Class A-1 Common Stock and the Pubco Warrants.”

“consist of a number of individuals (appointed in accordance with applicable NYSE rules) to be determined by the Company with the approval of the Purchaser (which approval shall not be unreasonably withheld, delayed or conditioned)”.

“who shall satisfy applicable NYSE independence and other listing requirements”.

“Listing. The Parties shall use their reasonable best efforts to cause: (a) Pubco’s initial listing application with the NYSE in connection with the transactions contemplated by this Agreement to have been approved; (b) Pubco to satisfy all applicable initial and continuing listing requirements of the NYSE; and (c) the shares of Pubco Class A-1 Common Stock and the Pubco Warrants issuable in accordance with this Agreement to be approved for listing on the NYSE. The Company and its counsel shall prepare, file, and respond to supplemental information requests with respect to, an application to list such securities on the NYSE (and the Purchaser and Pubco shall reasonably cooperate in connection therewith), as promptly as reasonably practicable after the date of Amendment No. 1 to this Agreement, and in any event prior to the Closing Date.”

“(e) NYSE Listing. The NYSE shall have notified the Parties that it has approved, or intends to approve prior to Closing, the application to list on the NYSE the shares of Pubco Class A-1 Common Stock to be issued in connection with the Transactions, subject only to official notice of issuance and any requirement to have a sufficient number of round-lot holders of the Pubco Common Stock (provided that this condition shall not apply to the extent the shares of Pubco Class A-1 Common Stock have not been conditionally approved for listing due to a failure to meet any “market value of publicly held securities” or similarly titled requirement as a result of the Company not causing a sufficient number of Seller Contributions to be made for Pubco Class A-1 Common Stock).”

“NYSE” means the New York Stock Exchange LLC.”

[Signature pages follow]

IN WITNESS WHEREOF, the Parties hereto have caused this Amendment to be executed by their respective authorized representatives as of the date first written above.

[Signature Page to Amendment to Business Combination Agreement and Company Disclosure Letter]