| Segment Reporting |
Information about the one reportable segment, significant segment expenses and a reconciliation to condensed consolidated net income is as follows (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | Revenue, net | | $ | 716,000 | | | $ | 659,903 | | | $ | 2,129,935 | | | $ | 1,821,784 | | | Operating expenses: | | | | | | | | | | Direct service costs, excluding depreciation and amortization - Employee compensation | | 165,451 | | | 149,295 | | | 493,143 | | | 441,164 | | | Direct service costs, excluding depreciation and amortization - Other segment items (a) | | 39,400 | | | 37,040 | | | 112,537 | | | 108,813 | | | Reimbursed out-of-pocket expenses | | 287,264 | | | 276,629 | | | 902,407 | | | 716,505 | | | Total direct costs | | 492,115 | | | 462,964 | | | 1,508,087 | | | 1,266,482 | | | Selling, general and administrative | | 51,765 | | | 48,082 | | | 147,785 | | | 152,643 | | | Depreciation | | 6,425 | | | 6,813 | | | 19,731 | | | 20,284 | | | Amortization | | 155 | | | 236 | | | 465 | | | 709 | | | Total operating expenses | | 550,460 | | | 518,095 | | | 1,676,068 | | | 1,440,118 | | | Income from operations | | 165,540 | | | 141,808 | | | 453,867 | | | 381,666 | | | Other income, net: | | | | | | | | | | Miscellaneous income (expense), net | | 17 | | | (489) | | | 841 | | | (5,180) | | | Interest income, net | | 5,349 | | | 1,517 | | | 15,452 | | | 9,058 | | | Total other income, net | | 5,366 | | | 1,028 | | | 16,293 | | | 3,878 | | | Income before income taxes | | 170,906 | | | 142,836 | | | 470,160 | | | 385,544 | | | Income tax provision | | 33,446 | | | 31,701 | | | 87,468 | | | 69,554 | | | Segment net income | | $ | 137,460 | | | $ | 111,135 | | | $ | 382,692 | | | $ | 315,990 | | | | | | | | | | | | Reconciliation of profit or loss | | | | | | | | | | Adjustments and reconciling items | | — | | | — | | | — | | | — | | | Condensed consolidated net income | | $ | 137,460 | | | $ | 111,135 | | | $ | 382,692 | | | $ | 315,990 | |
(a) Direct service costs, excluding depreciation and amortization - Other segment items includes costs related to inventory, leases, project subcontractors and other direct service costs.
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| Summary of Revenue by Major Source |
The following table disaggregates the Company’s revenue by major source (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | Therapeutic Area | | | | | | | | | | Metabolic | | $ | 209,242 | | | $ | 199,256 | | | $ | 665,867 | | | $ | 495,144 | | | Oncology | | 229,927 | | | 192,635 | | | 640,538 | | | 551,669 | | | Other | | 99,955 | | | 106,398 | | | 291,552 | | | 320,296 | | | Central Nervous System | | 83,649 | | | 65,627 | | | 246,714 | | | 181,657 | | | Cardiology | | 61,409 | | | 59,470 | | | 177,652 | | | 176,333 | | | AVAI | | 31,818 | | | 36,517 | | | 107,612 | | | 96,685 | | | Total revenue | | $ | 716,000 | | | $ | 659,903 | | | $ | 2,129,935 | | | $ | 1,821,784 | |
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