Exhibit 23.3

Consent of Lucid Capital Markets, LLC

October 16, 2026

Board of Directors

Synlogic, Inc.

PO Box 30

Winchester, MA 01890

Re: Registration Statement on Form S-4 of Synlogic, Inc.

Members of the Board:

We hereby consent to the inclusion of our opinion letter, dated April 13, 2026, to the Board of Directors of Synlogic, Inc. (“SBYX”) as Annex E to, and to the reference thereto under the headings “Prospectus Summary — Opinion of Lucid for Synlogic’s Board of Directors,” “The Merger — Background of the Merger,” “The Merger — Synlogic’s Reasons for the Merger,” and “The Merger — Opinion of Synlogic’s Financial Advisor” in the proxy statement/prospectus relating to the proposed merger involving SYBX and Caldera Therapeutics, Inc. (“Caldera”), which such proxy statement/prospectus forms a part of SYBX’s and Caldera’s Registration Statement on Form S-4 (the “Registration Statement”) to be filed on the date hereof, which this consent is filed as an exhibit thereto. In giving the foregoing consent, we do not admit (1) that we come within the category of persons whose consent is required under Section 7 of the Securities Act of 1933, as amended (the “Securities Act”), or the rules and regulations of the Securities and Exchange Commission (the “Commission”) promulgated thereunder, or (2) that we are experts with respect to any part of the Registration Statement within the meaning of the term “experts” as used in the Securities Act and the rules and regulations of the Commission promulgated thereunder.

 

Very truly yours,   /s / LUCID CAPITAL MARKETS, LLC

LUCID CAPITAL MARKETS, LLC

LUCID CAPITAL MARKETS, LLC

570 Lexington Ave, 40th Floor

New York NY 10022