Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Denominator: Weighted Average Number of Shares Outstanding, Diluted [Abstract] Trading Arrangement: Trading Arrangement [Axis] Maximum Maximum [Member] Statistical Measurement Statistical Measurement [Domain] Title of 12(b) Security Title of 12(b) Security Document Fiscal Year Focus Document Fiscal Year Focus Adjustment to Compensation, Amount Adjustment to Compensation Amount Financial Instrument Financial Instrument [Axis] Segment Reporting [Abstract] Schedule of Investments Fair Value Measurement on Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Common stock, $0.001 par value— 500,000,000 shares authorized as of August 31, 2026 and November 30, 2025; 109,200,394 and 101,807,484 shares issued and outstanding as of August 31, 2026 and November 30, 2025, respectively Common Stock, Value, Issued Accrued compensation Employee-related Liabilities, Current Restatement Determination Date Restatement Determination Date Maturities of marketable securities Proceeds from Sale, Maturity and Collection of Investments Contract assets Contract with Customer, Asset, after Allowance for Credit Loss Class of Warrant or Right Class of Warrant or Right [Domain] Number of warrants (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Deferred collaboration funding, net of current portion Collaborative Arrangement, Deferred Collaboration Funding, Noncurrent Collaborative Arrangement, Deferred Collaboration Funding, Noncurrent Voting rights Common Stock, Voting Rights For Shareholders Common Stock, Voting Rights For Shareholders Amendment Flag Amendment Flag Current liabilities: Liabilities, Current [Abstract] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Unrealized loss Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Amortized cost, short-term Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss, Current At the Market Offering At The Market Offerings [Member] At the market offerings. Other comprehensive loss, net of tax: Other Comprehensive Income (Loss), Net of Tax [Abstract] Related Party Transactions Related Party Transactions Disclosure [Text Block] Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Equity Distribution Agreement Equity Distribution Agreement [Member] Equity distribution agreement. Laboratory equipment Laboratory Equipment [Member] Laboratory equipment. 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Weighted-average exercise price, options granted (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Extension payment Proceeds From Collaboration Agreement, Extension Payment Proceeds From Collaboration Agreement, Extension Payment Purchases of marketable securities Payments to Acquire Marketable Securities Accumulated other comprehensive income (loss) Accumulated Other Comprehensive Income (Loss), Net of Tax Entity Shell Company Entity Shell Company Operating lease liabilities, current Operating Lease, Liability, Current Greater than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer Schedule of Property and Equipment Property, Plant, and Equipment [Table Text Block] Net Income (Loss) Per Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Reportable Segment Reportable Segment [Member] Reportable Segment Earnings Per Share [Abstract] Earnings Per Share [Abstract] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Total liabilities Liabilities Trading Symbol Trading Symbol Estimated fair value Debt Securities, Available-for-Sale, Excluding Accrued Interest Geographical [Domain] Geographical [Domain] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Total compensation cost related to stock-based awards yet to recognize Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Software in progress Software, In-Development [Member] Marketable securities, non‑current Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss, Noncurrent Company Selected Measure Name Company Selected Measure Name Sale of Stock Sale of Stock [Domain] Transaction Transaction [Domain] Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Fair Value Measurements Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block] Unrealized gain (loss) on available-for-sale marketable securities OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax Supplemental disclosures of non-cash investing and financing activities: Noncash Investing and Financing Items [Abstract] Certain sales milestones payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Certain Sales Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Certain Sales Milestones Depreciation and amortization Depreciation, Depletion and Amortization, Nonproduction Schedule of Common Stock Shares Reserved for Future Issuance Schedule Of Common Stock Shares Reserved For Future Issuance Table [Table Text Block] Schedule of common stock shares reserved for future issuance. 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Issuance costs, common stock Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Proceeds from issuances of common stock in “at the market” financing, net of issuance costs Proceeds from issuance of common stock Proceeds from Issuance of Common Stock Common stock, shares authorized (in shares) Common stock, shares authorized to issue (in shares) Common Stock, Shares Authorized Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Deferred collaboration funding, current Collaborative Arrangement, Deferred Collaboration Funding, Current Collaborative Arrangement, Deferred Collaboration Funding, Current Number of shares issued (in shares) Sale of Stock, Number of Shares Issued in Transaction Schedule of RSU Activity Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Exercise Price Award Exercise Price Cash flows from investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Related Party Transaction [Axis] Related Party Transaction [Axis] Segment Reporting [Line Items] Segment Reporting [Line Items] Document Quarterly Report Document Quarterly Report Weighted-average price per share (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Segments [Domain] Segments [Domain] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Issuance of pre funded warrants Stock Issued During Period, Value, New Issues And Adjustments To Additional Paid In Capital, Warrant Issued Stock Issued During Period, Value, New Issues And Adjustments To Additional Paid In Capital, Warrant Issued Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Equity Component Equity Component [Domain] PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Unrealized gain, long-term Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Noncurrent Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Noncurrent Adoption Date Trading Arrangement Adoption Date Counterparty Name Counterparty Name [Domain] Total stockholdersʼ equity Beginning balance Ending balance Equity, Attributable to Parent Collaboration revenue Collaboration Revenue [Member] Collaboration Revenue Equity Incentive Plans Equity Incentive Plans [Member] Equity Incentive Plans Assets Assets [Abstract] Title Trading Arrangement, Individual Title Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Accounting Policies [Abstract] Accounting Policies [Abstract] Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Number of drug candidates Number Of Drug Candidates Number Of Drug Candidates Marketable securities, non‑current Debt Securities, Available-for-Sale, Excluding Accrued Interest, Noncurrent Operating lease, liability Operating Lease, Liability Insider Trading Policies and Procedures [Line Items] Options outstanding, beginning balance (in shares) Options outstanding, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Upfront payment of additional fees Upfront Payment Of Additional Fees Upfront payment of additional fees. 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Tenant improvements Tenant Improvements Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Exercise of stock options (in shares) Options exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Weighted-average grant date fair value, RSUs granted (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value License revenue License Revenue [Member] License Revenue Collaboration revenue recognized from opening contract liability Contract with Customer, Liability, Revenue Recognized Accrued taxes Taxes Payable, Current Accumulated deficit Retained Earnings [Member] Operating lease liabilities, net of current portion Operating Lease, Liability, Noncurrent Total operating expenses Operating Expenses Money market funds Money Market Funds [Member] Weighted-average grant date fair value, RSUs forfeited (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Options forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Common stock, shares outstanding (in shares) Common Stock, Shares, Outstanding Award Timing Disclosures [Line Items] Corporate debt securities Corporate Debt Securities [Member] Net income (loss) per share, diluted (in USD per share) Earnings Per Share, Diluted Entity Current Reporting Status Entity Current Reporting Status Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Total Shareholder Return Amount Total Shareholder Return Amount Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Research and development Cost sharing allocation offset to research and development expenses Total research and development expenses Research and Development Expense Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Share-Based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Cash flows from financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Total revenue Revenue Revenue from Contract with Customer, Excluding Assessed Tax Property and equipment, net Total property and equipment, net Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Maintenance costs and real estate taxes Variable Lease, Payment Issuance of Series D redeemable convertible preferred stock, per share (in USD per share) Shares Issued, Price Per Share Pre Funded Warrants - 2024 Pre Funded Warrants - 2024 [Member] Pre Funded Warrants - 2024 Financial Instruments Financial Instruments [Domain] Other Risks and Uncertainties Other Risks And Uncertainties [Policy Text Block] Other risks and uncertainties policy. Remaining stock available for sale Sale Of Stock, Common Stock Remaining Available For Sale Sale Of Stock, Common Stock Remaining Available For Sale Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Underlying Securities Award Underlying Securities Amount Expiration term Collaboration Agreement Expiration Term Collaboration Agreement Expiration Term Roche Roche [Member] Roche Issuance of common stock in “at the market” financing, net of issuance costs Stock Issued During Period, Value, New Issues Underwriters Over-Allotment Option [Member] Weighted-average exercise price, options forfeited (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Segment Reporting [Table] Segment Reporting [Table] Shares available for grant under the stock plans (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Two Thousand Twenty Four Equity Inducement Plan Two Thousand Twenty Four Equity Inducement Plan [Member] Two Thousand Twenty Four Equity Inducement Plan Schedule Of Related Party Transactions By Related Party [Table] Related Party Transaction [Table] Minimum common stock holding percentage Minimum Common Stock Holding Percentage Minimum common stock holding percentage. 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Greater than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss Equity Components Equity Components [Axis] Accounts receivable Increase (Decrease) in Accounts Receivable Product and Service [Domain] Product and Service [Domain] Class Of Stock [Line Items] Class of Stock [Line Items] Collaborative Arrangement, Milestones [Axis] Collaborative Arrangement, Milestones [Axis] Collaborative Arrangement, Milestones Entity Interactive Data Current Entity Interactive Data Current Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Contribution expense Defined Contribution Plan, Cost Entity Small Business Entity Small Business Total comprehensive income (loss) Comprehensive Income (Loss), Net of Tax, Attributable to Parent Termination Date Trading Arrangement Termination Date Property, Plant, and Equipment [Line Items] Property, Plant, and Equipment [Line Items] Schedule of Accrued Expenses and Other Current Liabilities Schedule Of Accrued Expenses And Other Current Liabilities Table [Table Text Block] Schedule of accrued expenses and other current liabilities. Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value, Recurring and Nonrecurring [Table] Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Other Other Liabilities, Current Stock Plans and ESPP Stock Plans And Employee Stock Purchase Plan [Member] Stock plans and employee stock purchase plan. Collaboration Cost-Sharing Arrangements Collaborative Arrangement, Accounting Policy [Policy Text Block] Other assets Other Assets, Noncurrent Document Type Document Type Bexobrutideg (NX-5948) Bexobrutideg (NX-5948) [Member] Bexobrutideg (NX-5948) Transfers Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value as of Grant Date Award Grant Date Fair Value Number of performance obligations Number Of Performance Obligations Number Of Performance Obligations Allowance for credit losses Debt Securities, Available-for-Sale, Allowance for Credit Loss, Excluding Accrued Interest Schedule of Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Reconciliation of cash, cash equivalents and restricted cash: Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation [Abstract] Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Included in cash and cash equivalents Cash and Cash Equivalents [Member] Arrangement Duration Trading Arrangement Duration Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Local Phone Number Local Phone Number Drug targets Number Of Specified Drug Targets Number Of Specified Drug Targets Deferred revenue, net of current portion Contract with Customer, Liability, Noncurrent Upfront payment Upfront Payment Upfront payment. Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Registrant Name Entity Registrant Name Less than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss Pfizer Pfizer [Member] Pfizer Income (loss) before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Commitments and contingencies (Note 6) Commitments and Contingencies Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Total property and equipment, gross Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Income Tax Contingency [Table] Income Tax Contingency [Table] Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Executive Category: Executive Category [Axis] Regulatory milestone payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Regulatory Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Regulatory Milestones Furniture and fixtures Furniture and Fixtures [Member] Counterparty Name Counterparty Name [Axis] Liabilities and stockholdersʼ equity Liabilities and Equity [Abstract] Other Commitments [Table] Other Commitments [Table] Award Type Award Type [Domain] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount U.S. government agency securities US Government Agencies Debt Securities [Member] Transaction Type Transaction Type [Axis] PEO Name PEO Name Geographical [Axis] Geographical [Axis] Leasehold improvements Leasehold Improvements [Member] Recorded deferred revenue Contract with Customer, Liability Cash equivalents and marketable securities Cash, Cash Equivalents, and Short-Term Investments Long-Lived Asset, Class Long-Lived Asset, Class [Axis] Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Entity Tax Identification Number Entity Tax Identification Number Legal Entity [Axis] Legal Entity [Axis] Other Commitments [Line Items] Other Commitments [Line Items] Weighted-average exercise price, options exercised (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Total cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Accrued professional services Accrued Professional Fees, Current Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Accounts payable Increase (Decrease) in Accounts Payable Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Total additional payment Collaborative Arrangement, Total Additional Payment Collaborative Arrangement, Total Additional Payment Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Non-NEOs Non-NEOs [Member] Products arising from collaboration Number Of Products Arising From Collaboration Number Of Products Arising From Collaboration Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Registered Direct Offerings Registered Direct Offerings [Member] Registered direct offerings. Shares available for issuance under employee stock purchase plan Employee Stock Shares expected to be purchased under employee stock purchase plan Employee Stock [Member] Expenses related to the healthcare plan premiums Related Party Transaction, Amounts of Transaction Loss on disposal of property and equipment Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property Unrealized gain, short-term Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Current Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Current Net income (loss) per share, basic (in USD per share) Earnings Per Share, Basic Piper Sandler & Co. Piper Sandler And Co [Member] Piper Sandler & Co. Deferred revenue, current Contract with Customer, Liability, Current Total current assets Assets, Current Statistical Measurement Statistical Measurement [Axis] Insider Trading Arrangements [Line Items] Award Type Award Type [Axis] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Amortized cost Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss Accounts receivable Accounts Receivable, after Allowance for Credit Loss, Current Deferred collaboration funding Increase (Decrease) in Deferred Collaboration Funding Increase (Decrease) in Deferred Collaboration Funding Accumulated deficit Retained Earnings (Accumulated Deficit) Product and Service [Axis] Product and Service [Axis] Restricted cash Restricted cash Restricted Cash, Noncurrent Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Common stock Common Stock [Member] Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Shares issued (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Organization Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block] Cover [Abstract] Cover [Abstract] Collaborative Arrangement, Milestones [Domain] Collaborative Arrangement, Milestones [Domain] Collaborative Arrangement, Milestones [Domain] Equity Awards Adjustments Equity Awards Adjustments [Member] Collaboration Agreements Collaborative Arrangement Disclosure [Text Block] Total liabilities and stockholdersʼ equity Liabilities and Equity Options to purchase common stock issued and outstanding Employee Stock Option Options to purchase common stock issued and outstanding Share-Based Payment Arrangement, Option [Member] Segments [Axis] Segments [Axis] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Related Party Related and Nonrelated Parties [Domain] Plan Name Plan Name [Axis] Accrued interest receivable Interest Receivable, Current Tabular List, Table Tabular List [Table Text Block] Name Awards Close in Time to MNPI Disclosures, Individual Name 2024 Public Offering Public Offering 2024 [Member] Public Offering 2024 Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] RSUs forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period General and administrative General and Administrative Expense Long-Lived Asset, Class Long-Lived Asset, Class [Domain] Sale price of stock (in USD per share) Sale of Stock, Price Per Share Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Schedule Of Property Plant And Equipment [Table] Property, Plant, and Equipment [Table] Preferred stock, $0.001 par value— 10,000,000 shares authorized as of August 31, 2026 and November 30, 2025; no shares issued and outstanding as of August 31, 2026 and November 30, 2025 Preferred Stock, Value, Issued Adjustment to Compensation: Adjustment to Compensation [Axis] Accrued expenses and other current liabilities Increase (Decrease) in Other Accounts Payable and Accrued Liabilities Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Extended research term Contractual Extended Research Period Contractual extended research period. Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Marketable securities, current Estimated fair value, short-term Debt Securities, Available-for-Sale, Excluding Accrued Interest, Current Additional payment received to exercise option to expand number of targets Additional Payment Received To Exercise Option To Expand Number Of Targets Additional payment received to exercise option to expand number of targets. Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Name Measure Name Income Taxes Income Tax Disclosure [Text Block] Accounts payable Accounts Payable, Current Pay vs Performance Disclosure [Line Items] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Exercise of pre-funded warrants (in shares) Stock Issued During Period, Shares, Warrants Exercised Stock Issued During Period, Shares, Warrants Exercised Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Additional paid-in capital Additional Paid-in Capital [Member] Entity Filer Category Entity Filer Category Total Debt Securities, Available-for-Sale, Unrealized Loss Position Name Trading Arrangement, Individual Name Gilead Agreement Gilead Agreement [Member] Gilead agreement. Cash and cash equivalents Cash and cash equivalents Cash and Cash Equivalent Operating lease expenses, excluding variable lease payments Operating Lease, Expense Company Selected Measure Amount Company Selected Measure Amount Target licensing and reservation payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Target Licensing And Reservation Revenue, Remaining Performance Obligation, Variable Consideration Amount, Target Licensing And Reservation Entity Address, Address Line Two Entity Address, Address Line Two Schedule Of Stock By Class [Table] Stock, Class of Stock [Table] Warrants offering expenses Warrants Offering Expenses Warrants offering expenses. Current assets: Assets, Current [Abstract] Non-PEO NEO Non-PEO NEO [Member] Entity Address, Address Line One Entity Address, Address Line One Right-of-use assets recognized in exchange for lease obligations Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Weighted-average grant date fair value, RSUs vested (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Provision for income taxes Income Tax Expense (Benefit) Additional drug targets Number Of Additional Specified Drug Targets Number Of Additional Specified Drug Targets Award Timing Method Award Timing Method [Text Block] Net increase (decrease) in cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Total accrued expenses and other current liabilities Accrued And Other Liabilities Current Accrued and other liabilities current. Collaboration agreement contract term Collaboration Agreement Contract Term Collaboration agreement contract term. Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Numerator: Net Income (Loss) Attributable to Parent [Abstract] Net income (loss) Net income (loss) Net income (loss) Net Income (Loss) Attributable to Parent Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Balance Sheet Location Location, Statement of Financial Position, Balance [Axis] Statement [Table] Statement [Table] Proceeds from issuance of warrants Proceeds from Issuance of Warrants Restatement Determination Date: Restatement Determination Date [Axis] Proceeds from exercise of stock options Proceeds from Stock Options Exercised Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Vesting of restricted stock units Stock Issued During Period, Value, Restricted Stock Award, Gross Shares available for future equity grants Share-Based Payment Arrangement [Member] Defined Contribution Plan Defined Contribution Plan [Text Block] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]