Exhibit 21.1
SUBSIDIARIES
| Subsidiary | Place of incorporation |
| 1225 Boltonfield Street, LLC | Delaware |
| 160 Comfort Road, LLC | Delaware |
| 200 W 24th Holdings LLC | Delaware |
| 2178 State Highway 29A LLC | New York |
| 256 County Route 117 Perth LLC | Delaware |
| 320204 Nevada Holdings Corp. | Nevada |
| 320204 Oregon Holdings Corp. | Oregon |
| 320204 US Holdings Corp. | Delaware |
| Ace Heritage, LLC | New York |
| Agribusiness Holdings Limited Partnership | Oregon |
| Arches IP, Inc. | Delaware |
| Bridgewell Agribusiness LLC | Oregon |
| Budget King, LLC | California |
| BWAB Canada ULC | British Columbia (Canada) |
| BWAB Holdings, LLC | Oregon |
| C21 Investments Inc. | British Columbia (Canada) |
| Choice Organics, Inc. | Colorado |
| Clearlake Growth Fund II, Inc. | California |
| CO Acquisition Vehicle LLC | Delaware |
| Deep Roots Aria AcqCo, Inc. | Nevada |
| Deep Roots Harvest, Inc. | Nevada |
| Deep Roots Holdings, Inc. | Nevada |
| Deep Roots Operating, Inc. | Nevada |
| Deep Roots Properties, LLC | Nevada |
| DP Retail 100, LLC | Colorado |
| DP Retail 101, LLC | Colorado |
| DP Retail 102, LLC | Colorado |
| DP Retail 103, LLC | Colorado |
| DP Retail 104, LLC | Colorado |
| DP Retail 105, LLC | Colorado |
| DP Retail 106, LLC | Colorado |
| DP Retail 107, LLC | Colorado |
| DP Retail 109, LLC | Colorado |
| DP Retail 110, LLC | Colorado |
| DP Retail 111, LLC | Colorado |
| DP Retail 112 LLC | Colorado |
| DP Retail 113 LLC | Colorado |
| DP Retail 114 LLC | Colorado |
| DP Retail 115 LLC | Colorado |
| DP Retail 117, LLC | Colorado |
| DPC Denver, LLC | Colorado |
| DPM Colorado, LLC | Colorado |
| Eaze California LLC | Delaware |
| Eaze Colorado LLC | Delaware |
| Eaze Florida LLC | Delaware |
| Eaze, Inc. | Delaware |
| ECSD Management, LLC | California |
| FarmX, LLC | Pennsylvania |
| Green Dragon Florida LLC | Florida |
| Hawthorne Hydroponics LLC | Delaware |
| Healthy Healing Holistic Options, Inc. | California |
| HGCI LLC | Nevada |
| HiColor, LLC | Minnesota |
| Hometown Heart, Inc. | Wyoming |
| MaryMed LLC | Maryland |
| MJ Distributing C201, LLC | Nevada |
| MJ Distributing P132, LLC | Nevada |
| New Growth Horizon, LLC | Missouri |
| Nirvana Investments, LLC | Missouri |
| Prolific Brands of California, LLC | Delaware |
| Prolific IP Holdings, LLC | Delaware |
| Prolific Supply BW Holdings GP, LLC | Delaware |
| Prolific Supply BW Holdings, LLC | Delaware |
| Prolific Supply Holdco LLC | Delaware |
| Prolific Supply LLC | Delaware |
| Resurgent Biosciences, Inc. | Delaware |
| Retail Management Associates, LLC | Arizona |
| Silver State Cultivation LLC | Nevada |
| Silver State Relief LLC | Nevada |
| The Hawthorne Gardening Company LLC | Delaware |
| Verdant Grove, LLC | Delaware |
| Vireo Glass House, LLC | Delaware |
| Vireo Growth Inc. | British Columbia (Canada) |
| Vireo Health De Puerto Rico LLC | Puerto Rico |
| Vireo Health of Arcadia, LLC | Delaware |
| Vireo Health of CO II, LLC | Delaware |
| Vireo Health of CO, LLC | Delaware |
| Vireo Health of CO Fourth Peak, LLC | Delaware |
| Vireo Health of CO Fourth Peak Holdings, LLC | Delaware |
| Vireo Health of Colorado, LLC | Colorado |
| Vireo Health of Denver Metro, LLC | Delaware |
| Vireo Health of DTC, LLC | Delaware |
| Vireo Health of Foothills, LLC | Delaware |
| Vireo Health of Las Cruces, LLC | Delaware |
| Vireo Health of Mile High, LLC | Delaware |
| Vireo Health of Minnesota, LLC | Minnesota |
| Vireo Health of Nevada I, LLC | Nevada |
| Vireo Health of NM, LLC | Delaware |
| Vireo Health of Noco, LLC | Delaware |
| Vireo Health of PA, LLC | Delaware |
| Vireo Health of Puerto Rico, LLC | Delaware |
| Vireo Health of Rocky Mountain, LLC | Delaware |
| Vireo Health of Santa Fe, LLC | Delaware |
| Vireo Health of Soco, LLC | Delaware |
| Vireo Health of Western Slope, LLC | Delaware |
| Vireo Health, Inc. | Delaware |
| Vireo Marketing, LLC | Minnesota |
| Vireo of Charm City, LLC | Maryland |
| Vireo PR Merger Sub II Inc. | Missouri |
| Vireo PR Merger Sub Inc. | Missouri |
| Vireo Property Holdings, LLC | Delaware |
| Vireo Property Holdings 2, LLC | Delaware |
| Vireo Property Holdings New York, LLC | Delaware |
| Vireo Property Holdings Florida, LLC | Delaware |
| Vive Penn, LLC | Delaware |
| WC Staffing, LLC | Utah |
| Wholesome AG, LLC | Utah |
| Wholesome Direct, LLC | Utah |
| Wholesome Goods, LLC | Utah |
| Wholesome Therapy, LLC | Utah |
| WholesomeCo, Inc. | Delaware |
| Workforce Concepts 21 Inc. | Oregon |