v3.26.3
Income Taxes (Tables)
12 Months Ended
Dec. 31, 2025
Income Tax Disclosure [Abstract]  
Schedule of Reconciliation of Effective Tax Rate
The reconciliation of income taxes computed at the federal statutory rate to the Company’s effective income tax rate for the year ended December 31, 2025, prepared in accordance with ASC 740 as amended by ASU 2023-09, is as follows (in thousands, except percentages):
 
     Year Ended December 31, 2025  
     Amount        %     
Income tax computed at the federal statutory tax rate
   $ (12,221 )       21.0 % 
Tax credits
     (1,220 )       2.1  
Change in valuation allowance
     11,966        (20.6 ) 
Nontaxable or nondeductible items
     
Other non-deductible permanent items
     (93 )       0.2  
Limitation on officer compensation
     425        (0.7 ) 
Stock compensation
     1,142        (2.0 ) 
Other
     1        —   
  
 
 
    
 
 
 
Income tax expense (benefit)
   $ —         —  % 
  
 
 
    
 
 
 
The reconciliation of income taxes computed at the federal statutory rate to the Company’s effective income tax rate for the year ended December 31, 2024 (prior to adoption of ASU 2023-09) was as follows (in thousands, except percentages):
 
     Year Ended December 31, 2024  
     Amount        %    
Income tax computed at the federal statutory tax rate
   $ (13,726 )       21.0 % 
State and local income taxes, net of federal benefit
     (4,126 )       6.3  
Tax credits
     (4,347 )       6.7  
Change in valuation allowance
      20,544        (31.5 ) 
Other permanent differences
     (31 )       —   
Stock compensation
     607        (0.9 ) 
Uncertain tax position
     1,065        (1.6 ) 
Other
     14        —   
  
 
 
    
 
 
 
Income tax expense (benefit)
   $ —         —  % 
  
 
 
    
 
 
 
Schedule of Significant Components of Deferred Income Taxes
Significant components of deferred tax assets and liabilities as of December 31, 2025 and 2024 were as follows (in thousands):
 
     As of December 31,  
     2025      2024  
Deferred tax assets:
     
Net operating loss carryforwards
   $ 45,574      $ 27,618  
Research tax credits
     10,124        8,313  
Lease liability
     13,769        13,335  
Capitalized R&D
     15,726        20,155  
Intangible assets
     39        44  
Other, net
     2,268        2,637  
  
 
 
    
 
 
 
Total deferred tax assets
     87,500        72,102  
Less valuation allowance
     (75,150 )       (58,844 ) 
  
 
 
    
 
 
 
Net deferred tax assets
     12,350        13,258  
Deferred tax liabilities:
     
ROU asset
     (12,259 )       (13,169 ) 
Property and equipment
     (91 )       (89 ) 
  
 
 
    
 
 
 
Total deferred tax liabilities
     (12,350 )       (13,258 ) 
  
 
 
    
 
 
 
Net deferred tax assets
   $ —       $ —   
  
 
 
    
 
 
 
Schedule of Activity in Valuation Allowance
Activity in the valuation allowance for the years ended December 31, 2025 and 2024 was as follows (in thousands):
 
     Year Ended December 31,  
     2025       2024    
Balance, beginning of period
     58,844        38,323  
Charged to federal income tax expense
     11,966        14,047  
Charged to state income tax expense
     4,324        6,497  
Charged (credited) to other comprehensive loss
     16        (23 ) 
  
 
 
    
 
 
 
Balance, end of period
     75,150        58,844  
  
 
 
    
 
 
 
Summary of Net Operating Loss Carryforward
As of December 31, 2025 and 2024, federal net operating loss (“NOL”) carryforwards, state NOL carryforwards, and research and development tax credit carryforwards consisted of the following (in thousands):
 
     As of December 31,  
     2025      2024  
Federal NOL carryforwards
   $ 161,402      $ 91,864  
State NOL carryforwards
   $ 231,270      $ 183,313  
Federal research and development tax credit carryforwards
   $ 9,294      $ 7,667  
State research tax credit carryforwards
   $ 5,850      $ 4,853  
Summary of Gross Unrecognized Tax Benefits
Activity related to the Company’s gross unrecognized tax benefits for the years ended December 31, 2025 and 2024 was as follows (in thousands):
 
     Year Ended December 31,  
      2025        2024   
Balance at beginning of period
   $ 9,212      $ 8,048  
Increase related to current year positions
     656         1,164  
  
 
 
    
 
 
 
Balance at the end of the year
   $ 9,868      $ 9,212