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            <identifier scheme="http://www.sec.gov/CIK">0001757499</identifier>
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            <startDate>2026-09-09</startDate>
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    <dei:AmendmentFlag contextRef="AsOf2026-09-09" id="Fact000003">true</dei:AmendmentFlag>
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    <dei:EntityRegistrantName contextRef="AsOf2026-09-09" id="Fact000011">SHUTTLE PHARMACEUTICALS HOLDINGS, INC.</dei:EntityRegistrantName>
    <dei:EntityIncorporationStateCountryCode contextRef="AsOf2026-09-09" id="Fact000012">DE</dei:EntityIncorporationStateCountryCode>
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    <dei:EntityTaxIdentificationNumber contextRef="AsOf2026-09-09" id="Fact000014">82-5089826</dei:EntityTaxIdentificationNumber>
    <dei:EntityAddressAddressLine1 contextRef="AsOf2026-09-09" id="Fact000015">401 Professional Drive</dei:EntityAddressAddressLine1>
    <dei:EntityAddressAddressLine2 contextRef="AsOf2026-09-09" id="Fact000016">Suite 260</dei:EntityAddressAddressLine2>
    <dei:EntityAddressCityOrTown contextRef="AsOf2026-09-09" id="Fact000017">Gaithersburg</dei:EntityAddressCityOrTown>
    <dei:EntityAddressStateOrProvince contextRef="AsOf2026-09-09" id="Fact000018">MD</dei:EntityAddressStateOrProvince>
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    <dei:LocalPhoneNumber contextRef="AsOf2026-09-09" id="Fact000021">430-4212</dei:LocalPhoneNumber>
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    <dei:PreCommencementTenderOffer contextRef="AsOf2026-09-09" id="Fact000024">false</dei:PreCommencementTenderOffer>
    <dei:PreCommencementIssuerTenderOffer contextRef="AsOf2026-09-09" id="Fact000025">false</dei:PreCommencementIssuerTenderOffer>
    <dei:Security12bTitle contextRef="AsOf2026-09-09" id="Fact000026">Common     Stock $0.00001 per share</dei:Security12bTitle>
    <dei:TradingSymbol contextRef="AsOf2026-09-09" id="Fact000027">SHPH</dei:TradingSymbol>
    <dei:SecurityExchangeName contextRef="AsOf2026-09-09" id="Fact000028">NASDAQ</dei:SecurityExchangeName>
    <dei:EntityEmergingGrowthCompany contextRef="AsOf2026-09-09" id="Fact000029">true</dei:EntityEmergingGrowthCompany>
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    <dei:AmendmentDescription contextRef="AsOf2026-09-09" id="Fact000032">On
September 15, 2026, Shuttle Pharmaceuticals Holdings, Inc. (the &#x201c;Company&#x201d;) filed a Current Report on Form 8-K (the &#x201c;Form
8-K&#x201d;) under Item 3.02 disclosing, among other things, that the Company issued pre-funded warrants (the &#x201c;Pre-Funded Warrants&#x201d;)
to purchase an aggregate of approximately 16,932,508 shares of Common Stock, which number actually represents the maximum number of Pre-Funded
Warrants that may be issued upon the satisfaction of all conditions to issuance, and not the number of Pre-Funded Warrants that were
issued as of September 9, 2026. The Company hereby amends the Form 8-K to reflect that, as of September 9, 2026, the actual number of
Pre-Funded Warrants that have been issued is 9,741,751.This
Current Report on Form 8-K/A amends the Form 8-K solely to amend Item 3.02 as described above. There are no other modifications or updates
to any of the information made in the Form 8-K.</dei:AmendmentDescription>
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