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    <element id="SHPH_WarrantsAtFairValueInitialCost" name="WarrantsAtFairValueInitialCost" nillable="true" xbrli:periodType="instant" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_InvestmentUnitedDogecoin" name="InvestmentUnitedDogecoin" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingWeightedAverageExercisePrice" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingWeightedAverageExercisePrice" nillable="true" xbrli:periodType="instant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_SharebasedCompensationArrangementBySharebasedPaymentAwardNonOptionsOutstandingWeightedAverageRemainingContractualTerm" name="SharebasedCompensationArrangementBySharebasedPaymentAwardNonOptionsOutstandingWeightedAverageRemainingContractualTerm" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ShareBasedCompensationArrangementByShareBasedPaymetAwardNonOptionGrandInPeriodWeightedAverageExercisePrice" name="ShareBasedCompensationArrangementByShareBasedPaymetAwardNonOptionGrandInPeriodWeightedAverageExercisePrice" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_SharebasedCompensationArrangementBySharebasedPaymentAwardNonOptionsOutstandingGrantedWeightedAverageRemainingContractualTerm" name="SharebasedCompensationArrangementBySharebasedPaymentAwardNonOptionsOutstandingGrantedWeightedAverageRemainingContractualTerm" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PercentageOfSharesOutstanding" name="PercentageOfSharesOutstanding" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PrefundedWarrantsShares" name="PrefundedWarrantsShares" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionsOutstandingIntrinsicValue" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionsOutstandingIntrinsicValue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_DerivativeGainLossOnDerivativeWarrants" name="DerivativeGainLossOnDerivativeWarrants" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PrepaymentOfResearchCosts" name="PrepaymentOfResearchCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_AggregateCosts" name="AggregateCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_MergAgreementsDescription" name="MergAgreementsDescription" nillable="true" xbrli:periodType="instant" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_LossOnExtinguishmentOfContingentPayable" name="LossOnExtinguishmentOfContingentPayable" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_IssuanceOfPrefundedWarrantsInPipeNetOfIssuanceCosts" name="IssuanceOfPrefundedWarrantsInPipeNetOfIssuanceCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PrefundedWarrantsInPipeNetOfIssuanceCosts" name="PrefundedWarrantsInPipeNetOfIssuanceCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PreferredStockInPipeNetOfIssuanceCosts" name="PreferredStockInPipeNetOfIssuanceCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_IssuanceOfSeriesB2PreferredStockInPipeNetOfIssuanceCosts" name="IssuanceOfSeriesB2PreferredStockInPipeNetOfIssuanceCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_IssuanceOfSeriesB2PreferredStockInPipeNetOfIssuanceCostsShares" name="IssuanceOfSeriesB2PreferredStockInPipeNetOfIssuanceCostsShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_IssuanceCostsInAccountsPayableAndAccruedExpenses" name="IssuanceCostsInAccountsPayableAndAccruedExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_GainOnMarketableSecurities" name="GainOnMarketableSecurities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PaymentsOfStockIssuanceCostsOne" name="PaymentsOfStockIssuanceCostsOne" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ScheduleOfConsiderationPayableAndContingentConsiderationPayableTableTextBlock" name="ScheduleOfConsiderationPayableAndContingentConsiderationPayableTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_LiabilitiesExtinguishedThroughIssuanceOfEquity" name="LiabilitiesExtinguishedThroughIssuanceOfEquity" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
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    <element id="SHPH_PaymentsOfOtherObligations" name="PaymentsOfOtherObligations" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_BusinessCombinationContingentConsiderationLiabilityExchangedOrExtinguished" name="BusinessCombinationContingentConsiderationLiabilityExchangedOrExtinguished" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ReplacementConsiderationIssuedPursuantToSecondAmendment" name="ReplacementConsiderationIssuedPursuantToSecondAmendment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_BusinessCombinationContingentConsiderationLiabilityPayments" name="BusinessCombinationContingentConsiderationLiabilityPayments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ConsiderationPayablePayments" name="ConsiderationPayablePayments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_FairValueOfMilestonePreFundedWarrantsIssued" name="FairValueOfMilestonePreFundedWarrantsIssued" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ReplacementConsideration" name="ReplacementConsideration" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_CarryingValueOfConsiderationPayableExtinguished" name="CarryingValueOfConsiderationPayableExtinguished" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PrepaymentOfShareRepurchaseRecordedInAdditionalPaidInCapital" name="PrepaymentOfShareRepurchaseRecordedInAdditionalPaidInCapital" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ScheduleOfLossOnExtinguishmentOfContingentPayableTableTextBlock" name="ScheduleOfLossOnExtinguishmentOfContingentPayableTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_CommonStockUponAchievementOfSpecifiedAdditionalMilestoneEvents" name="CommonStockUponAchievementOfSpecifiedAdditionalMilestoneEvents" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_MergerAgreementsDescription" name="MergerAgreementsDescription" nillable="true" xbrli:periodType="instant" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_StockIssuedDuringPeriodValueShareholderContribution" name="StockIssuedDuringPeriodValueShareholderContribution" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_StockIssuedDuringPeriodSharesShareholderContribution" name="StockIssuedDuringPeriodSharesShareholderContribution" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_ShareholderContributionArisingFromTdrPursuantToMolecule.aiSecondAmendment" name="ShareholderContributionArisingFromTdrPursuantToMolecule.aiSecondAmendment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="SHPH_PlannedCapitalRaiseAmount" name="PlannedCapitalRaiseAmount" nillable="true" xbrli:periodType="duration" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
</schema>
