<?xml version="1.0" encoding="us-ascii" standalone="yes"?>
<!--XBRL Document Created with XBRLMaster-->
<!--Version: 2.3.08-->
<!--Based on XBRL 2.1-->
<!--Date of creation: 09/17/2026-->
<!--Software architectural design and coding: A'c Dharmapremananda Avt.-->
<!--Copyright (c) 2026 I-NET Business Solutions, Inc. All Rights Reserved.-->
<link:linkbase xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://upxi.com/role/Cover" xlink:href="upxi-20260630.xsd#Cover" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ConsolidatedBalanceSheets" xlink:href="upxi-20260630.xsd#ConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:href="upxi-20260630.xsd#ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ConsolidatedStatementsOfOperations" xlink:href="upxi-20260630.xsd#ConsolidatedStatementsOfOperations" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ConsolidatedStatementsOfStockholdersDeficitEquity" xlink:href="upxi-20260630.xsd#ConsolidatedStatementsOfStockholdersDeficitEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ConsolidatedStatementsOfCashFlows" xlink:href="upxi-20260630.xsd#ConsolidatedStatementsOfCashFlows" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/CompanyInformationAndBasisOfPresentation" xlink:href="upxi-20260630.xsd#CompanyInformationAndBasisOfPresentation" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SignificantAccountingPolicies" xlink:href="upxi-20260630.xsd#SignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/Inventory" xlink:href="upxi-20260630.xsd#Inventory" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PrepaidExpensesAndOtherAssets" xlink:href="upxi-20260630.xsd#PrepaidExpensesAndOtherAssets" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/DigitalAssets" xlink:href="upxi-20260630.xsd#DigitalAssets" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PropertyAndEquipment" xlink:href="upxi-20260630.xsd#PropertyAndEquipment" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IntangibleAssets" xlink:href="upxi-20260630.xsd#IntangibleAssets" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/Leases" xlink:href="upxi-20260630.xsd#Leases" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/AccruedLiabilitiesAndAcquisitionPayable" xlink:href="upxi-20260630.xsd#AccruedLiabilitiesAndAcquisitionPayable" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotes" xlink:href="upxi-20260630.xsd#ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotes" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/RelatedPartyTransactions" xlink:href="upxi-20260630.xsd#RelatedPartyTransactions" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/EquityTransactions" xlink:href="upxi-20260630.xsd#EquityTransactions" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/StockBasedCompensation" xlink:href="upxi-20260630.xsd#StockBasedCompensation" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PhantomStockAppreciationPlan" xlink:href="upxi-20260630.xsd#PhantomStockAppreciationPlan" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxes" xlink:href="upxi-20260630.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ExitOfManufacturingAndDistributionOperations" xlink:href="upxi-20260630.xsd#ExitOfManufacturingAndDistributionOperations" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/RisksAndUncertainties" xlink:href="upxi-20260630.xsd#RisksAndUncertainties" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SegmentInformation" xlink:href="upxi-20260630.xsd#SegmentInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SubsequentEvents" xlink:href="upxi-20260630.xsd#SubsequentEvents" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SignificantAccountingPoliciesPolicies" xlink:href="upxi-20260630.xsd#SignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SignificantAccountingPoliciesTables" xlink:href="upxi-20260630.xsd#SignificantAccountingPoliciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/InventoryTables" xlink:href="upxi-20260630.xsd#InventoryTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PrepaidExpensesAndOtherAssetsTables" xlink:href="upxi-20260630.xsd#PrepaidExpensesAndOtherAssetsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/DigitalAssetsTables" xlink:href="upxi-20260630.xsd#DigitalAssetsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PropertyAndEquipmentTables" xlink:href="upxi-20260630.xsd#PropertyAndEquipmentTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IntangibleAssetsTables" xlink:href="upxi-20260630.xsd#IntangibleAssetsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/LeasesTables" xlink:href="upxi-20260630.xsd#LeasesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/AccruedLiabilitiesAndAcquisitionPayableTables" xlink:href="upxi-20260630.xsd#AccruedLiabilitiesAndAcquisitionPayableTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesTables" xlink:href="upxi-20260630.xsd#ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/StockBasedCompensationTables" xlink:href="upxi-20260630.xsd#StockBasedCompensationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PhantomStockAppreciationPlanTables" xlink:href="upxi-20260630.xsd#PhantomStockAppreciationPlanTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxesTables" xlink:href="upxi-20260630.xsd#IncomeTaxesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SignificantAccountingPoliciesDetails" xlink:href="upxi-20260630.xsd#SignificantAccountingPoliciesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SignificantAccountingPoliciesDetails1" xlink:href="upxi-20260630.xsd#SignificantAccountingPoliciesDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SignificantAccountingPoliciesDetails2" xlink:href="upxi-20260630.xsd#SignificantAccountingPoliciesDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SignificantAccountingPoliciesDetailsNarrative" xlink:href="upxi-20260630.xsd#SignificantAccountingPoliciesDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/InventoryDetails" xlink:href="upxi-20260630.xsd#InventoryDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/InventoryDetailsNarrative" xlink:href="upxi-20260630.xsd#InventoryDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PrepaidExpensesAndOtherAssetsDetails" xlink:href="upxi-20260630.xsd#PrepaidExpensesAndOtherAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/DigitalAssetsDetails" xlink:href="upxi-20260630.xsd#DigitalAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/DigitalAssetsDetails1" xlink:href="upxi-20260630.xsd#DigitalAssetsDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/DigitalAssetsDetails2" xlink:href="upxi-20260630.xsd#DigitalAssetsDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/DigitalAssetsDetailsNarrative" xlink:href="upxi-20260630.xsd#DigitalAssetsDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PropertyAndEquipmentDetails" xlink:href="upxi-20260630.xsd#PropertyAndEquipmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PropertyAndEquipmentDetailsNarrative" xlink:href="upxi-20260630.xsd#PropertyAndEquipmentDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IntangibleAssetsDetails" xlink:href="upxi-20260630.xsd#IntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IntangibleAssetsDetails1" xlink:href="upxi-20260630.xsd#IntangibleAssetsDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IntangibleAssetsDetailsNarrative" xlink:href="upxi-20260630.xsd#IntangibleAssetsDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/LeasesDetails" xlink:href="upxi-20260630.xsd#LeasesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/LeasesDetails1" xlink:href="upxi-20260630.xsd#LeasesDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/LeasesDetails2" xlink:href="upxi-20260630.xsd#LeasesDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/LeasesDetailsNarrative" xlink:href="upxi-20260630.xsd#LeasesDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/AccruedLiabilitiesDetails" xlink:href="upxi-20260630.xsd#AccruedLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/AccruedLiabilitiesDetails1" xlink:href="upxi-20260630.xsd#AccruedLiabilitiesDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails" xlink:href="upxi-20260630.xsd#ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails1" xlink:href="upxi-20260630.xsd#ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails2" xlink:href="upxi-20260630.xsd#ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetailsNarrative" xlink:href="upxi-20260630.xsd#ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/RelatedPartyTransactionsDetailsNarrative" xlink:href="upxi-20260630.xsd#RelatedPartyTransactionsDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/EquityTransactionsDetailsNarrative" xlink:href="upxi-20260630.xsd#EquityTransactionsDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/StockBasedCompensationDetails" xlink:href="upxi-20260630.xsd#StockBasedCompensationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/StockBasedCompensationDetails1" xlink:href="upxi-20260630.xsd#StockBasedCompensationDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/StockBasedCompensationDetails2" xlink:href="upxi-20260630.xsd#StockBasedCompensationDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/StockBasedCompensationDetails3" xlink:href="upxi-20260630.xsd#StockBasedCompensationDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/StockBasedCompensationDetailsNarrative" xlink:href="upxi-20260630.xsd#StockBasedCompensationDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/PhantomStockAppreciationPlanDetails" xlink:href="upxi-20260630.xsd#PhantomStockAppreciationPlanDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxesDetails" xlink:href="upxi-20260630.xsd#IncomeTaxesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxesDetails1" xlink:href="upxi-20260630.xsd#IncomeTaxesDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxesDetails2" xlink:href="upxi-20260630.xsd#IncomeTaxesDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxesDetails3" xlink:href="upxi-20260630.xsd#IncomeTaxesDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxesDetails4" xlink:href="upxi-20260630.xsd#IncomeTaxesDetails4" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/IncomeTaxesDetailsNarrative" xlink:href="upxi-20260630.xsd#IncomeTaxesDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/ExitOfManufacturingAndDistributionOperationsDetailsNarrative" xlink:href="upxi-20260630.xsd#ExitOfManufacturingAndDistributionOperationsDetailsNarrative" xlink:type="simple" />
  <link:roleRef roleURI="http://upxi.com/role/SubsequentEventsDetailsNarrative" xlink:href="upxi-20260630.xsd#SubsequentEventsDetailsNarrative" xlink:type="simple" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/Cover" xlink:title="00000001 - Document - Document and Entity Information" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ConsolidatedBalanceSheets" xlink:title="110200 - Statement - CONSOLIDATED BALANCE SHEETS">
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaapAssetsCurrent" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaapAccountsReceivableNetCurrent" />
    <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsCurrent" xlink:to="loc_us-gaapAccountsReceivableNetCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaapInventoryNet" />
    <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsCurrent" xlink:to="loc_us-gaapInventoryNet" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent" />
    <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsCurrent" xlink:to="loc_us-gaapPrepaidExpenseAndOtherAssetsCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CryptoAssetFairValueCurrent" xlink:label="loc_us-gaapCryptoAssetFairValueCurrent" />
    <link:calculationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsCurrent" xlink:to="loc_us-gaapCryptoAssetFairValueCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" />
    <link:calculationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsCurrent" xlink:to="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_PurchasePriceReceivableVitamedicaCurrent" xlink:label="loc_upxiPurchasePriceReceivableVitamedicaCurrent" />
    <link:calculationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsCurrent" xlink:to="loc_upxiPurchasePriceReceivableVitamedicaCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_RelatedPartyTransactionDueFromRelatedPartiesCurrent" xlink:label="loc_upxiRelatedPartyTransactionDueFromRelatedPartiesCurrent" />
    <link:calculationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsCurrent" xlink:to="loc_upxiRelatedPartyTransactionDueFromRelatedPartiesCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsNoncurrent" xlink:label="loc_us-gaapAssetsNoncurrent" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaapPropertyPlantAndEquipmentNet" />
    <link:calculationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsNoncurrent" xlink:to="loc_us-gaapPropertyPlantAndEquipmentNet" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaapIntangibleAssetsNetExcludingGoodwill" />
    <link:calculationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsNoncurrent" xlink:to="loc_us-gaapIntangibleAssetsNetExcludingGoodwill" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaapGoodwill" />
    <link:calculationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsNoncurrent" xlink:to="loc_us-gaapGoodwill" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxAssetsNet" xlink:label="loc_us-gaapDeferredIncomeTaxAssetsNet" />
    <link:calculationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsNoncurrent" xlink:to="loc_us-gaapDeferredIncomeTaxAssetsNet" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CryptoAssetFairValueNoncurrent" xlink:label="loc_us-gaapCryptoAssetFairValueNoncurrent" />
    <link:calculationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsNoncurrent" xlink:to="loc_us-gaapCryptoAssetFairValueNoncurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaapOtherAssetsNoncurrent" />
    <link:calculationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsNoncurrent" xlink:to="loc_us-gaapOtherAssetsNoncurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaapOperatingLeaseRightOfUseAsset" />
    <link:calculationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssetsNoncurrent" xlink:to="loc_us-gaapOperatingLeaseRightOfUseAsset" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets" xlink:label="loc_us-gaapAssets" />
    <link:calculationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssets" xlink:to="loc_us-gaapAssetsCurrent" xlink:type="arc" weight="1" />
    <link:calculationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapAssets" xlink:to="loc_us-gaapAssetsNoncurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaapLiabilitiesCurrent" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaapAccountsPayableCurrent" />
    <link:calculationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapAccountsPayableCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredCompensationLiabilityCurrent" xlink:label="loc_us-gaapDeferredCompensationLiabilityCurrent" />
    <link:calculationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapDeferredCompensationLiabilityCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredRevenueCurrent" xlink:label="loc_us-gaapDeferredRevenueCurrent" />
    <link:calculationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapDeferredRevenueCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaapAccruedLiabilitiesCurrent" />
    <link:calculationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapAccruedLiabilitiesCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestPayableCurrent" xlink:label="loc_us-gaapInterestPayableCurrent" />
    <link:calculationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapInterestPayableCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NotesPayableCurrent" xlink:label="loc_us-gaapNotesPayableCurrent" />
    <link:calculationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapNotesPayableCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShortTermBorrowings" xlink:label="loc_us-gaapShortTermBorrowings" />
    <link:calculationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapShortTermBorrowings" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_NotesPayableCygnetSubsidiaryCurrent" xlink:label="loc_upxiNotesPayableCygnetSubsidiaryCurrent" />
    <link:calculationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_upxiNotesPayableCygnetSubsidiaryCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="loc_us-gaapOperatingLeaseLiabilityCurrent" />
    <link:calculationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_us-gaapOperatingLeaseLiabilityCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_PortionOfAcquisitionNotePayableCurrent" xlink:label="loc_upxiPortionOfAcquisitionNotePayableCurrent" />
    <link:calculationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesCurrent" xlink:to="loc_upxiPortionOfAcquisitionNotePayableCurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesNoncurrent" xlink:label="loc_us-gaapLiabilitiesNoncurrent" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaapOperatingLeaseLiabilityNoncurrent" />
    <link:calculationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesNoncurrent" xlink:to="loc_us-gaapOperatingLeaseLiabilityNoncurrent" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConvertibleLongTermNotesPayable" xlink:label="loc_us-gaapConvertibleLongTermNotesPayable" />
    <link:calculationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesNoncurrent" xlink:to="loc_us-gaapConvertibleLongTermNotesPayable" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaapStockholdersEquity" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaapPreferredStockValue" />
    <link:calculationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapPreferredStockValue" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaapCommonStockValue" />
    <link:calculationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapCommonStockValue" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="loc_us-gaapAdditionalPaidInCapital" />
    <link:calculationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapAdditionalPaidInCapital" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaapRetainedEarningsAccumulatedDeficit" />
    <link:calculationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapStockholdersEquity" xlink:to="loc_us-gaapRetainedEarningsAccumulatedDeficit" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaapLiabilitiesAndStockholdersEquity" />
    <link:calculationArc order="34" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquity" xlink:to="loc_us-gaapLiabilitiesCurrent" xlink:type="arc" weight="1" />
    <link:calculationArc order="35" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquity" xlink:to="loc_us-gaapLiabilitiesNoncurrent" xlink:type="arc" weight="1" />
    <link:calculationArc order="36" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapLiabilitiesAndStockholdersEquity" xlink:to="loc_us-gaapStockholdersEquity" xlink:type="arc" weight="1" />
  </link:calculationLink>
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:title="110201 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ConsolidatedStatementsOfOperations" xlink:title="124100 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS">
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues" xlink:label="loc_us-gaapRevenues" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_RevenueFromOperations" xlink:label="loc_upxiRevenueFromOperations" />
    <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapRevenues" xlink:to="loc_upxiRevenueFromOperations" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaapRevenueFromContractWithCustomerExcludingAssessedTax" />
    <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapRevenues" xlink:to="loc_us-gaapRevenueFromContractWithCustomerExcludingAssessedTax" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit" xlink:label="loc_us-gaapGrossProfit" />
    <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapGrossProfit" xlink:to="loc_us-gaapRevenues" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaapCostOfRevenue" />
    <link:calculationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapGrossProfit" xlink:to="loc_us-gaapCostOfRevenue" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses" xlink:label="loc_us-gaapOperatingExpenses" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingAndMarketingExpense" xlink:label="loc_us-gaapSellingAndMarketingExpense" />
    <link:calculationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapSellingAndMarketingExpense" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductionAndDistributionCosts" xlink:label="loc_us-gaapProductionAndDistributionCosts" />
    <link:calculationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapProductionAndDistributionCosts" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="loc_us-gaapGeneralAndAdministrativeExpense" />
    <link:calculationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapGeneralAndAdministrativeExpense" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CryptoAssetRealizedLossOperating" xlink:label="loc_us-gaapCryptoAssetRealizedLossOperating" />
    <link:calculationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapCryptoAssetRealizedLossOperating" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_CryptoAssetRealizedLossOnSale" xlink:label="loc_upxiCryptoAssetRealizedLossOnSale" />
    <link:calculationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_upxiCryptoAssetRealizedLossOnSale" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaapAllocatedShareBasedCompensationExpense" />
    <link:calculationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapAllocatedShareBasedCompensationExpense" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaapAmortizationOfIntangibleAssets" />
    <link:calculationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapAmortizationOfIntangibleAssets" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Depreciation" xlink:label="loc_us-gaapDepreciation" />
    <link:calculationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapDepreciation" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_OperatingLeaseImpairmentIncome" xlink:label="loc_upxiOperatingLeaseImpairmentIncome" />
    <link:calculationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_upxiOperatingLeaseImpairmentIncome" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_ImpairmentOnAssetsFromManufacturingShutDown" xlink:label="loc_upxiImpairmentOnAssetsFromManufacturingShutDown" />
    <link:calculationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_upxiImpairmentOnAssetsFromManufacturingShutDown" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaapImpairmentOfIntangibleAssetsFinitelived" />
    <link:calculationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_us-gaapImpairmentOfIntangibleAssetsFinitelived" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_UnrealizedLossGainOnDigitalAssetsAmount" xlink:label="loc_upxiUnrealizedLossGainOnDigitalAssetsAmount" />
    <link:calculationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingExpenses" xlink:to="loc_upxiUnrealizedLossGainOnDigitalAssetsAmount" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaapOperatingIncomeLoss" />
    <link:calculationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingIncomeLoss" xlink:to="loc_us-gaapOperatingExpenses" xlink:type="arc" weight="-1" />
    <link:calculationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapOperatingIncomeLoss" xlink:to="loc_us-gaapGrossProfit" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaapNonoperatingIncomeExpense" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseNonoperating" xlink:label="loc_us-gaapInterestExpenseNonoperating" />
    <link:calculationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_us-gaapInterestExpenseNonoperating" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaapGainsLossesOnExtinguishmentOfDebt" />
    <link:calculationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_us-gaapGainsLossesOnExtinguishmentOfDebt" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingExpense" xlink:label="loc_us-gaapOtherNonoperatingExpense" />
    <link:calculationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNonoperatingIncomeExpense" xlink:to="loc_us-gaapOtherNonoperatingExpense" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" />
    <link:calculationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="loc_us-gaapOperatingIncomeLoss" xlink:type="arc" weight="1" />
    <link:calculationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="loc_us-gaapNonoperatingIncomeExpense" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss" />
    <link:calculationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetIncomeLoss" xlink:to="loc_us-gaapIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaapIncomeTaxExpenseBenefit" />
    <link:calculationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetIncomeLoss" xlink:to="loc_us-gaapIncomeTaxExpenseBenefit" xlink:type="arc" weight="-1" />
  </link:calculationLink>
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ConsolidatedStatementsOfStockholdersDeficitEquity" xlink:title="148600 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS (DEFICIT) EQUITY" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ConsolidatedStatementsOfCashFlows" xlink:title="170000 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS">
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaapNetIncomeLoss" />
    <link:calculationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapNetIncomeLoss" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationAndAmortization" xlink:label="loc_us-gaapDepreciationAndAmortization" />
    <link:calculationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapDepreciationAndAmortization" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_CryptoAssetRealizedLossOnSale" xlink:label="loc_upxiCryptoAssetRealizedLossOnSale" />
    <link:calculationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_upxiCryptoAssetRealizedLossOnSale" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_CryptoDigitalAssetRevenueConversionToUSDollar" xlink:label="loc_upxiCryptoDigitalAssetRevenueConversionToUSDollar" />
    <link:calculationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_upxiCryptoDigitalAssetRevenueConversionToUSDollar" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CryptoAssetRealizedLossOperating" xlink:label="loc_us-gaapCryptoAssetRealizedLossOperating" />
    <link:calculationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapCryptoAssetRealizedLossOperating" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AmortizationOfFinancingCosts" xlink:label="loc_us-gaapAmortizationOfFinancingCosts" />
    <link:calculationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapAmortizationOfFinancingCosts" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaapGainsLossesOnExtinguishmentOfDebt" />
    <link:calculationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapGainsLossesOnExtinguishmentOfDebt" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryWriteDown" xlink:label="loc_us-gaapInventoryWriteDown" />
    <link:calculationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapInventoryWriteDown" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProvisionForDoubtfulAccounts" xlink:label="loc_us-gaapProvisionForDoubtfulAccounts" />
    <link:calculationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapProvisionForDoubtfulAccounts" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_ReductionOfAcquisitionPayable" xlink:label="loc_upxiReductionOfAcquisitionPayable" />
    <link:calculationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_upxiReductionOfAcquisitionPayable" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims" xlink:label="loc_us-gaapIssuanceOfStockAndWarrantsForServicesOrClaims" />
    <link:calculationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIssuanceOfStockAndWarrantsForServicesOrClaims" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaapShareBasedCompensation" />
    <link:calculationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapShareBasedCompensation" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaapIncreaseDecreaseInAccountsReceivable" />
    <link:calculationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInAccountsReceivable" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaapIncreaseDecreaseInInventories" />
    <link:calculationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInInventories" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaapIncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" />
    <link:calculationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOperatingLeaseLiability" xlink:label="loc_us-gaapIncreaseDecreaseInOperatingLeaseLiability" />
    <link:calculationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInOperatingLeaseLiability" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="loc_us-gaapIncreaseDecreaseInAccountsPayableAndAccruedLiabilities" />
    <link:calculationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:label="loc_us-gaapIncreaseDecreaseInDeferredRevenue" />
    <link:calculationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapIncreaseDecreaseInDeferredRevenue" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xlink:label="loc_us-gaapGainLossOnSaleOfPropertyPlantEquipment" />
    <link:calculationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapGainLossOnSaleOfPropertyPlantEquipment" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CryptoAssetUnrealizedGainLossOperating" xlink:label="loc_us-gaapCryptoAssetUnrealizedGainLossOperating" />
    <link:calculationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapCryptoAssetUnrealizedGainLossOperating" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CryptoAssetSale" xlink:label="loc_us-gaapCryptoAssetSale" />
    <link:calculationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapCryptoAssetSale" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_OperatingLeaseImpairmentGainOnSettlement" xlink:label="loc_upxiOperatingLeaseImpairmentGainOnSettlement" />
    <link:calculationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_upxiOperatingLeaseImpairmentGainOnSettlement" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_ImpairmentOnAssetsFromManufacturingShutDown" xlink:label="loc_upxiImpairmentOnAssetsFromManufacturingShutDown" />
    <link:calculationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_upxiImpairmentOnAssetsFromManufacturingShutDown" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaapImpairmentOfIntangibleAssetsFinitelived" />
    <link:calculationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:to="loc_us-gaapImpairmentOfIntangibleAssetsFinitelived" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromSaleOfBuildings" xlink:label="loc_us-gaapProceedsFromSaleOfBuildings" />
    <link:calculationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_us-gaapProceedsFromSaleOfBuildings" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromSaleOfOtherProductiveAssets" xlink:label="loc_us-gaapProceedsFromSaleOfOtherProductiveAssets" />
    <link:calculationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_us-gaapProceedsFromSaleOfOtherProductiveAssets" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_ProceedsFromTheSaleOfVitamedicaInc" xlink:label="loc_upxiProceedsFromTheSaleOfVitamedicaInc" />
    <link:calculationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_upxiProceedsFromTheSaleOfVitamedicaInc" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentForAcquisitionCryptoAsset" xlink:label="loc_us-gaapPaymentForAcquisitionCryptoAsset" />
    <link:calculationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_us-gaapPaymentForAcquisitionCryptoAsset" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_PaymentForAcquisitionOfRoyaltyInterest" xlink:label="loc_upxiPaymentForAcquisitionOfRoyaltyInterest" />
    <link:calculationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_upxiPaymentForAcquisitionOfRoyaltyInterest" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaapPaymentsToAcquirePropertyPlantAndEquipment" />
    <link:calculationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_us-gaapPaymentsToAcquirePropertyPlantAndEquipment" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_ProceedsFromTheSaleOfECore" xlink:label="loc_upxiProceedsFromTheSaleOfECore" />
    <link:calculationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_upxiProceedsFromTheSaleOfECore" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromDisposalCryptoAsset" xlink:label="loc_us-gaapProceedsFromDisposalCryptoAsset" />
    <link:calculationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:to="loc_us-gaapProceedsFromDisposalCryptoAsset" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaapProceedsFromIssuanceOfCommonStock" />
    <link:calculationArc order="34" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromIssuanceOfCommonStock" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="loc_us-gaapProceedsFromWarrantExercises" />
    <link:calculationArc order="35" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromWarrantExercises" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:label="loc_us-gaapPaymentsForRepurchaseOfCommonStock" />
    <link:calculationArc order="36" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapPaymentsForRepurchaseOfCommonStock" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromShortTermDebt" xlink:label="loc_us-gaapProceedsFromShortTermDebt" />
    <link:calculationArc order="37" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromShortTermDebt" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfShortTermDebt" xlink:label="loc_us-gaapRepaymentsOfShortTermDebt" />
    <link:calculationArc order="38" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapRepaymentsOfShortTermDebt" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromConvertibleDebt" xlink:label="loc_us-gaapProceedsFromConvertibleDebt" />
    <link:calculationArc order="39" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromConvertibleDebt" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfOtherDebt" xlink:label="loc_us-gaapRepaymentsOfOtherDebt" />
    <link:calculationArc order="40" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapRepaymentsOfOtherDebt" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromRelatedPartyDebt" xlink:label="loc_us-gaapProceedsFromRelatedPartyDebt" />
    <link:calculationArc order="41" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromRelatedPartyDebt" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfRelatedPartyDebt" xlink:label="loc_us-gaapRepaymentsOfRelatedPartyDebt" />
    <link:calculationArc order="42" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapRepaymentsOfRelatedPartyDebt" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfStockIssuanceCosts" xlink:label="loc_us-gaapPaymentsOfStockIssuanceCosts" />
    <link:calculationArc order="43" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapPaymentsOfStockIssuanceCosts" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDebtIssuanceCosts" xlink:label="loc_us-gaapPaymentsOfDebtIssuanceCosts" />
    <link:calculationArc order="44" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapPaymentsOfDebtIssuanceCosts" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfNotesPayable" xlink:label="loc_us-gaapRepaymentsOfNotesPayable" />
    <link:calculationArc order="45" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapRepaymentsOfNotesPayable" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfOtherLongTermDebt" xlink:label="loc_us-gaapRepaymentsOfOtherLongTermDebt" />
    <link:calculationArc order="46" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapRepaymentsOfOtherLongTermDebt" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock" xlink:label="loc_us-gaapProceedsFromIssuanceOfPreferredStockAndPreferenceStock" />
    <link:calculationArc order="47" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromIssuanceOfPreferredStockAndPreferenceStock" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfConvertibleDebt" xlink:label="loc_us-gaapRepaymentsOfConvertibleDebt" />
    <link:calculationArc order="48" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapRepaymentsOfConvertibleDebt" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromOtherShortTermDebt" xlink:label="loc_us-gaapProceedsFromOtherShortTermDebt" />
    <link:calculationArc order="49" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_us-gaapProceedsFromOtherShortTermDebt" xlink:type="arc" weight="1" />
    <link:loc xlink:type="locator" xlink:href="upxi-20260630.xsd#upxi_RepaymentsOfRelatedPartyNotePayable" xlink:label="loc_upxiRepaymentsOfRelatedPartyNotePayable" />
    <link:calculationArc order="50" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:to="loc_upxiRepaymentsOfRelatedPartyNotePayable" xlink:type="arc" weight="-1" />
    <link:loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" />
    <link:calculationArc order="51" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="loc_us-gaapNetCashProvidedByUsedInOperatingActivities" xlink:type="arc" weight="1" />
    <link:calculationArc order="52" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="loc_us-gaapNetCashProvidedByUsedInInvestingActivities" xlink:type="arc" weight="1" />
    <link:calculationArc order="53" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaapCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="loc_us-gaapNetCashProvidedByUsedInFinancingActivities" xlink:type="arc" weight="1" />
  </link:calculationLink>
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/CompanyInformationAndBasisOfPresentation" xlink:title="995551 - Disclosure - Company Information and Basis of Presentation" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SignificantAccountingPolicies" xlink:title="995552 - Disclosure - Significant Accounting Policies" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/Inventory" xlink:title="995553 - Disclosure - Inventory" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PrepaidExpensesAndOtherAssets" xlink:title="995554 - Disclosure - Prepaid Expenses and Other Assets" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/DigitalAssets" xlink:title="995555 - Disclosure - Digital Assets" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PropertyAndEquipment" xlink:title="995556 - Disclosure - Property and Equipment" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IntangibleAssets" xlink:title="995557 - Disclosure - Intangible Assets" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/Leases" xlink:title="995558 - Disclosure - Leases" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/AccruedLiabilitiesAndAcquisitionPayable" xlink:title="995559 - Disclosure - Accrued Liabilities and Acquisition Payable" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotes" xlink:title="995560 - Disclosure - Short-Term Treasury Debt, Cygnet Subsidiary Notes Payable, Promissory Notes, and Convertible Notes" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/RelatedPartyTransactions" xlink:title="995561 - Disclosure - Related Party Transactions" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/EquityTransactions" xlink:title="995562 - Disclosure - Equity Transactions" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/StockBasedCompensation" xlink:title="995563 - Disclosure - Stock Based Compensation" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PhantomStockAppreciationPlan" xlink:title="995564 - Disclosure - Phantom Stock Appreciation Plan" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxes" xlink:title="995565 - Disclosure - Income Taxes" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ExitOfManufacturingAndDistributionOperations" xlink:title="995566 - Disclosure - Exit of Manufacturing and Distribution Operations" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/RisksAndUncertainties" xlink:title="995567 - Disclosure - Risks and Uncertainties" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SegmentInformation" xlink:title="995568 - Disclosure - Segment Information" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SubsequentEvents" xlink:title="995569 - Disclosure - Subsequent Events" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SignificantAccountingPoliciesPolicies" xlink:title="995570 - Disclosure - Significant Accounting Policies (Policies)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SignificantAccountingPoliciesTables" xlink:title="995571 - Disclosure - Significant Accounting Policies (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/InventoryTables" xlink:title="995572 - Disclosure - Inventory (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PrepaidExpensesAndOtherAssetsTables" xlink:title="995573 - Disclosure - Prepaid Expenses and Other Assets (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/DigitalAssetsTables" xlink:title="995574 - Disclosure - Digital Assets (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PropertyAndEquipmentTables" xlink:title="995575 - Disclosure - Property and Equipment (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IntangibleAssetsTables" xlink:title="995576 - Disclosure - Intangible Assets (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/LeasesTables" xlink:title="995577 - Disclosure - Leases (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/AccruedLiabilitiesAndAcquisitionPayableTables" xlink:title="995578 - Disclosure - Accrued Liabilities and Acquisition Payable (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesTables" xlink:title="995579 - Disclosure - Short-Term Treasury Debt, Cygnet Subsidiary Notes Payable, Promissory Notes, and Convertible Notes (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/StockBasedCompensationTables" xlink:title="995580 - Disclosure - Stock Based Compensation (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PhantomStockAppreciationPlanTables" xlink:title="995581 - Disclosure - Phantom Stock Appreciation Plan (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxesTables" xlink:title="995582 - Disclosure - Income Taxes (Tables)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SignificantAccountingPoliciesDetails" xlink:title="995583 - Disclosure - Significant Accounting Policies (Details )" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SignificantAccountingPoliciesDetails1" xlink:title="995584 - Disclosure - Significant Accounting Policies (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SignificantAccountingPoliciesDetails2" xlink:title="995585 - Disclosure - Significant Accounting Policies (Details 2)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SignificantAccountingPoliciesDetailsNarrative" xlink:title="995586 - Disclosure - Significant Accounting Policies (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/InventoryDetails" xlink:title="995587 - Disclosure - Inventory (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/InventoryDetailsNarrative" xlink:title="995588 - Disclosure - Inventory (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PrepaidExpensesAndOtherAssetsDetails" xlink:title="995589 - Disclosure - Prepaid Expenses and Other Assets (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/DigitalAssetsDetails" xlink:title="995590 - Disclosure - Digital Assets (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/DigitalAssetsDetails1" xlink:title="995591 - Disclosure - Digital Assets (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/DigitalAssetsDetails2" xlink:title="995592 - Disclosure - Digital Assets (Details 2)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/DigitalAssetsDetailsNarrative" xlink:title="995593 - Disclosure - Digital Assets (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PropertyAndEquipmentDetails" xlink:title="995594 - Disclosure - Property and Equipment (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PropertyAndEquipmentDetailsNarrative" xlink:title="995595 - Disclosure - Property and Equipment (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IntangibleAssetsDetails" xlink:title="995596 - Disclosure - Intangible Assets (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IntangibleAssetsDetails1" xlink:title="995597 - Disclosure - Intangible Assets (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IntangibleAssetsDetailsNarrative" xlink:title="995598 - Disclosure - Intangible Assets (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/LeasesDetails" xlink:title="995599 - Disclosure - Leases (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/LeasesDetails1" xlink:title="995600 - Disclosure - Leases (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/LeasesDetails2" xlink:title="995601 - Disclosure - Leases (Details 2)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/LeasesDetailsNarrative" xlink:title="995602 - Disclosure - Leases (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/AccruedLiabilitiesDetails" xlink:title="995603 - Disclosure - Accrued Liabilities (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/AccruedLiabilitiesDetails1" xlink:title="995604 - Disclosure - Accrued Liabilities (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails" xlink:title="995605 - Disclosure - Short-Term Treasury Debt, Cygnet Subsidiary Notes Payable, Promissory Notes, and Convertible Notes (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails1" xlink:title="995606 - Disclosure - Short-Term Treasury Debt, Cygnet Subsidiary Notes Payable, Promissory Notes, and Convertible Notes (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetails2" xlink:title="995607 - Disclosure - Short-Term Treasury Debt, Cygnet Subsidiary Notes Payable, Promissory Notes, and Convertible Notes (Details 2)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ShortTermTreasuryDebtCygnetSubsidiaryNotesPayablePromissoryNotesAndConvertibleNotesDetailsNarrative" xlink:title="995608 - Disclosure - Short-Term Treasury Debt, Cygnet Subsidiary Notes Payable, Promissory Notes, and Convertible Notes (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/RelatedPartyTransactionsDetailsNarrative" xlink:title="995609 - Disclosure - Related Party Transactions (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/EquityTransactionsDetailsNarrative" xlink:title="995610 - Disclosure - Equity Transactions (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/StockBasedCompensationDetails" xlink:title="995611 - Disclosure - Stock Based Compensation (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/StockBasedCompensationDetails1" xlink:title="995612 - Disclosure - Stock Based Compensation (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/StockBasedCompensationDetails2" xlink:title="995613 - Disclosure - Stock Based Compensation (Details 2)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/StockBasedCompensationDetails3" xlink:title="995614 - Disclosure - Stock Based Compensation (Details 3)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/StockBasedCompensationDetailsNarrative" xlink:title="995615 - Disclosure - Stock Based Compensation (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/PhantomStockAppreciationPlanDetails" xlink:title="995616 - Disclosure - Phantom Stock Appreciation Plan (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxesDetails" xlink:title="995617 - Disclosure - Income Taxes (Details)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxesDetails1" xlink:title="995618 - Disclosure - Income Taxes (Details 1)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxesDetails2" xlink:title="995619 - Disclosure - Income Taxes (Details 2)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxesDetails3" xlink:title="995620 - Disclosure - Income Taxes (Details 3)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxesDetails4" xlink:title="995621 - Disclosure - Income Taxes (Details 4)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/IncomeTaxesDetailsNarrative" xlink:title="995622 - Disclosure - Income Taxes (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/ExitOfManufacturingAndDistributionOperationsDetailsNarrative" xlink:title="995623 - Disclosure - Exit of Manufacturing and Distribution Operations (Details Narrative)" />
  <link:calculationLink xlink:type="extended" xlink:role="http://upxi.com/role/SubsequentEventsDetailsNarrative" xlink:title="995624 - Disclosure - Subsequent Events (Details Narrative)" />
</link:linkbase>
