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          <link:loc xlink:type="locator" xlink:href="clls-20260630.xsd#clls_ReserachTaxCreditReceivableCurrent" xlink:label="clls_ReserachTaxCreditReceivableCurrent"/>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of financial assets [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtAmortisedCost_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial liabilities at amortised cost</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtAmortisedCost_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accounting category amortized cost</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtAmortisedCost_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Financial liabilities at amortised cost</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentPrepaidExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current prepaid expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentPrepaidExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Prepaid expenses and other prepayments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfOutstandingBalancesWithRelatedPartiesExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of outstanding balances with related parties explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfOutstandingBalancesWithRelatedPartiesExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of outstanding balances with related parties explanatory [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfOutstandingBalancesWithRelatedPartiesExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of outstanding balances with related parties</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SalesOfNon-CurrentFinancialAssetsClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Sales of non-current financial assets, classified as investing activities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SalesOfNon-CurrentFinancialAssetsClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Sales of Non-Current Financial Assets, Classified as Investing Activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SalesOfNon-CurrentFinancialAssetsClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Sales of non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SalesOfNon-CurrentFinancialAssetsClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Proceeds from the sales of non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ReserveOfExchangeDifferencesOnTranslation_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reserve of exchange differences on translation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ReserveOfExchangeDifferencesOnTranslation_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Currency translation adjustment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashRepaymentsOfAdvancesAndLoansFromRelatedParties_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash repayments of advances and loans from related parties</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashRepaymentsOfAdvancesAndLoansFromRelatedParties_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Loan principal payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LandAndBuildingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Land and buildings [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LandAndBuildingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Land and Buildings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AstraZenecaIrelandMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Astra Zeneca Ireland [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AstraZenecaIrelandMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Astra Zeneca Ireland [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchAndDevelopmentExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Research and development expenses.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchAndDevelopmentExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Research and development expenses [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchAndDevelopmentExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Research and Development Expenses [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TopOfRangeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Top of range [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TopOfRangeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Top of Range [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughEffectOfChangesInForeignExchangeRatesLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through effect of changes in foreign exchange rates, liabilities arising from financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughEffectOfChangesInForeignExchangeRatesLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Currency translation adjustment financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherCurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other current assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherCurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Current Assets [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedDividendsWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expected dividends warrants.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedDividendsWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected Dividends Warrants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedDividendsWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected dividends</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantsValuationMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Warrants valuation method.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantsValuationMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Warrants Valuation Method</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantsValuationMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Valuation method</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through share-based payment transactions, equity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-cash stock-based compensation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfPropertyPlantAndEquipmentAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of property, plant and equipment [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfPropertyPlantAndEquipmentAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Classes of property, plant and equipment [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncomeTaxReceivableCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Income tax receivable current.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncomeTaxReceivableCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income Tax Receivable Current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncomeTaxReceivableCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income tax receivable</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Payments of lease liabilities, classified as financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Payments on lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Payments of lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInOtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase decrease in other income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInOtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase Decrease In Other Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInOtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfExercisableShareOptionsForfeitedInShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of exercisable share options forfeited in share based payment arrangement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfExercisableShareOptionsForfeitedInShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Exercisable Share Options Forfeited In Share Based Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfExercisableShareOptionsForfeitedInShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Option exercisable, forfeited or expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialInstitutionDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial Institution [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Initial investment agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Initial Investment Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementOneAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Agreement one.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementOneAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Agreement One [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfFinancialAssetsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of financial assets [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SAFreeSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">S A free shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SAFreeSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">S A Free Shares [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SAFreeSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">S A free shares [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentFiscalPeriodFocus_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Fiscal Period Focus</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentFiscalPeriodFocus_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Fiscal Period Focus</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DerivativesByNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Derivatives by name.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DerivativesByNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivatives By Name [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingPeriodShare-BasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Vesting period, share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingPeriodShare-BasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Vesting Period, Share-based Payment Arrangements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingPeriodShare-BasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Vesting period, years</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Purchase of other long-term assets, classified as investing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Acquisition of non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Purchase of other long-term assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_GrantAndRefundableAdvanceAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Grant And Refundable Advance Agreement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_GrantAndRefundableAdvanceAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Grant And Refundable Advance Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_GrantAndRefundableAdvanceAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Grant and refundable advance agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_GrantAndRefundableAdvanceAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Grant and Refundable Advance Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpenseByNatureTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">This table concepts are used to disclose the amount of expenses aggregated according to their nature (for example, depreciation, purchases of materials, transport costs, employee benefits and advertising costs), and not reallocated among functions within the entity.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpenseByNatureTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expense By Nature [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpenseByNatureTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expense By Nature [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash flows from (used in) financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/netLabel">Net cash flows from (used in) financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net cash used in financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ContractualCapitalCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contractual capital commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ContractualCapitalCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non current provisions used during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Current Provisions Used During the Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions Amounts used during period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ContractualCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Contractual commitments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ContractualCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contractual commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ContractualCommitments_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current financial assets (deposits)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule disclosing information related to details of non-current financial assets and other non-current assets explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule Disclosing Information Related to Details of Non-Current Financial Assets and Other Non-Current Assets Explanatory [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Non-current Financial Assets and Other Non-current Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_JointCollaborationAndResearchAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Joint collaboration and research agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_JointCollaborationAndResearchAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Joint collaboration and research agreement [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_JointCollaborationAndResearchAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Joint Collaboration and Research Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BorrowingExtendedPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Borrowing extended period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BorrowingExtendedPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Borrowing extended period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BorrowingExtendedPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Borrowing extended period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Effect of exchange rate changes on cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Effects of exchange rate changes on cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfReconciliationOfLiabilitiesArisingFromFinancingActivitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of reconciliation of liabilities arising from financing activities [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Agreement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Agreement [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsExercisableChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of share options exercisable change in conversion ratiosin sharebased payment arrangement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsExercisableChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Share Options Exercisable Change In Conversion Ratios In Sharebased Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsExercisableChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option exercisable, change in coversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassesOfCommitmentsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Classes of commitments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassesOfCommitmentsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of commitments [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfQuantitativeInformationAboutLeasesForLesseeAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of quantitative information about leases for lessee [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finance costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceCosts_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Financial expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceCosts_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel">Total Financial expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfChangesInIncomeTaxExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Percentage of changes in income tax expense.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfChangesInIncomeTaxExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Percentage Of Changes In Income Tax Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfChangesInIncomeTaxExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Percentage change</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AccrualsAndDeferredIncomeIncludingContractLiabilitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Accruals and deferred income including contract liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AccrualsAndDeferredIncomeIncludingContractLiabilitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accruals and deferred income including contract liabilities [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfExpectedTermOfShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The expected term of the options (in years) at grant date used to calculate the fair value of share options granted.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfExpectedTermOfShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description Of Expected Term Of Share Options Granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfExpectedTermOfShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected term (in years)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current financial liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current financial liabilities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current Financial Liabilities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NotLaterThanOneYearMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Not later than one year [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NotLaterThanOneYearMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Less than One Year [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingPeriodForShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Describes whether the instruments granted in share-based payment arrangements vest in instalments over a specified period (aka graded vesting) or vest all at once on a specified date (aka cliff vesting).</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingPeriodForShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Vesting Period For Share Based Payment Arrangements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingPeriodForShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Vesting period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OperatingExpensesAndOtherOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Operating (expenses) and other operating income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OperatingExpensesAndOtherOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Operating (expenses) and other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OperatingExpensesAndOtherOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total operating expenses and other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndServerance_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of provisions for employee litigation and serverance.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndServerance_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for employee litigation and serverance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndServerance_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Employee litigation and severance, Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndServerance_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Employee litigation and severance, Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InterestIncomeOnCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Interest income on cash, cash equivalents and financial assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InterestIncomeOnCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest income on cash, cash equivalents and financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InterestIncomeOnCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income from cash, cash equivalents and financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other provision for charges used during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Provision for Charges Used During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other provision for charges, Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SegmentsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segments [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfIntangibleAssetsAndGoodwillDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of intangible assets and goodwill [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MajorShareholdersDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Major Shareholders [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MajorShareholdersDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Major shareholders.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivablesDueToForeignExchangeImpact_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Non-current Research Tax Credit Receivables Due to Foreign Exchange Impact</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivablesDueToForeignExchangeImpact_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in non-current research tax credit receivables due to the foreign exchange impact</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivablesDueToForeignExchangeImpact_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase (decrease) in non-current research tax credit receivables due to the foreign exchange impact</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision for tax litigation during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision For Tax Litigation During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for tax litigation, During the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Financial liabilities at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Financial liabilities at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Book value on the statement of financial position</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Book value on the statement of financial position</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfAdditionalShareDueToChangeInConversionRatiosShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The weighted-average exercise price of stock options for which the conversion ratios were modified during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfAdditionalShareDueToChangeInConversionRatiosShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Exercise Price Of Additional Share Due To Change In Conversion Ratios Share Based Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfAdditionalShareDueToChangeInConversionRatiosShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted- average exercise price per share, Additional shares due to change in conversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair value of expected volatility amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value Of Expected Volatility Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected volatility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Fair value in $ thousands</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AmountToBeRepaid_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Amount to be repaid.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AmountToBeRepaid_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amount to be repaid</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConditionalAdvancesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Conditional Advances.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConditionalAdvancesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Conditional Advances [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutFairValueSharePriceTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of detailed information about fair value share price explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutFairValueSharePriceTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Detailed Information About Fair Value Share Price [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutFairValueSharePriceTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value of Initial Investment Agreement at Initial Recognition Date Determined on Basis of Share Price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TrancheCWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Tranche C Warrants [Member].</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TrancheCWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Tranche C Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Cash and cash equivalents at the end of the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Cash and cash equivalents at the beginning of the year</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLossFromOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Profit (loss) from operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLossFromOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Operating income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLossFromOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Operating income (loss) before tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLossFromOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Operating loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StateGuarantedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">State guaranted loan.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StateGuarantedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">State Guaranted Loan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Non-CurrentPortionOfState-GuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non-Current Portion of State-Guaranteed Loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Non-CurrentPortionOfState-GuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-Current Portion of State-Guaranteed Loan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Non-CurrentPortionOfState-GuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Non-Current Portion of State-Guaranteed Loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AccrualsAndDeferredIncomeIncludingContractLiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accruals and deferred income including contract liabilities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Assets [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">ASSETS</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TradeReceivablesAndOtherCurrentAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The entire disclosure of trade receivables and other current assets Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TradeReceivablesAndOtherCurrentAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trade receivables and other current assets Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TradeReceivablesAndOtherCurrentAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade receivables and other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_SegmentGeographicalDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Geographical [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GainsOnChangeInFairValueOfDerivatives_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Gains on change in fair value of derivatives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GainsOnChangeInFairValueOfDerivatives_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Gain on change in fair value measurement recognized</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GainsOnChangeInFairValueOfDerivatives_lbl" xlink:role="http://www.xbrl.org/2009/role/netLabel">Gain on fair value measurement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GainsOnChangeInFairValueOfDerivatives_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Gain in fair value recognized in profit and loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of transactions between related parties [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Comprehensive income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total Comprehensive income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure Of Number And Weighted Average Exercise Prices Of Share Options and Awards [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Number And Weighted Average Exercise Prices Of Share Options and Awards [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure Of Number And Weighted Average Exercise Prices Of Share Options and Awards [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income taxes paid (refund), classified as operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Income taxes refund (paid)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Income tax received (paid)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromSaleOfPreferredShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Proceeds from sale of preferred shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromSaleOfPreferredShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds From Sale Of Preferred Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromSaleOfPreferredShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Proceeds from sale of preferred shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditFinancingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Research tax credit financings.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditFinancingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Research Tax Credit Financings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditFinancingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Research Tax Credit Financings [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherCurrentLiabilities1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other current liabilities1.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherCurrentLiabilities1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Current Liabilities 1- [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherCurrentLiabilities1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other Current Liabilities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial liabilities at fair value through profit or loss, category [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial Liabilities at Fair Value through Profit or Loss, Category [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationOfReconciliationOfChangesInRightOfUseAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information of reconciliation of changes in right of use assets explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationOfReconciliationOfChangesInRightOfUseAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of detailed information of reconciliation of changes in right of use assets explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationOfReconciliationOfChangesInRightOfUseAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Detailed Information About Breakdown of Right-of-Use Assets Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExecutiveOfficersMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Executive Officers [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PensionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Pension.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PensionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Pension [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PensionMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Pension [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Deferred revenues.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred revenues and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Deferred revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentForDecreaseIncreaseInTradeReceivablesAndOtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Adjustment for decrease (increase) in trade receivables and other current assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentForDecreaseIncreaseInTradeReceivablesAndOtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustment for Decrease (Increase) in Trade Receivables and Other Current Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentForDecreaseIncreaseInTradeReceivablesAndOtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease (increase) in trade receivables and other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of share options exercisable granted in share based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Share Options Exercisable Granted In Share Based Payment Arrangements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option exercisable, granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Consolidated operations [table].</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Consolidated operations [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Consolidated operations [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValuesPerOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair values per options.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValuesPerOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair values per options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValuesPerOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value per options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CarryingAmountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Carrying amount [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CarryingAmountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Carrying amount [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for employee litigation and severance other comprehensive income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Employee Litigation And Severance Other Comprehensive Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Employee litigation and severance, OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Expected volatility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Total fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Total Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IntangibleAssetsOtherThanGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Intangible assets other than goodwill</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IntangibleAssetsOtherThanGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Intangible assets other than goodwill at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IntangibleAssetsOtherThanGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Intangible assets other than goodwill at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IntangibleAssetsOtherThanGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Intangible assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IntangibleAssetsOtherThanGoodwill_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total intangible assets other than goodwill</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesWithContingentFeaturesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial liabilities with contingent features [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AccrualsAndDeferredIncomeIncludingContractLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Accruals and deferred income including contract liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AccrualsAndDeferredIncomeIncludingContractLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accruals And Deferred Income Including Contract Liabilities [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProportionOfVotingPowerHeldInAssociate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proportion of voting rights held in associate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProportionOfVotingPowerHeldInAssociate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Voting rights held in associate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AmendedAndRestatedAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Amended and restated agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AmendedAndRestatedAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amended And Restated Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentValueAddedTaxPayables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current value added tax payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentValueAddedTaxPayables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">VAT Payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueAtMeasurementDateShareOptionsGrantedPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair value at measurement date share options granted per share.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueAtMeasurementDateShareOptionsGrantedPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value at Measurement Date Share Options Granted Per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueAtMeasurementDateShareOptionsGrantedPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Grant date share fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RevenueAndOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue and other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RevenueAndOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revenues and other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RevenueAndOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total revenues and other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RevenueAndOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">External revenues and other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableExercisedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average exercise price of share options exercisable exercised in share based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableExercisedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Exercise Price Of Share Options Exercisable Exercised In Share Based Payment Arrangements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableExercisedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted- average exercise price per share, exercised</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantExercisePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Warrant exercise price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantExercisePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Warrant Exercise price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantExercisePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Exercise price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CashAndCashEquivalentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cash and cash equivalent.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CashAndCashEquivalentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash and Cash Equivalent [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CashAndCashEquivalentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash and Cash Equivalents [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNonadjustingEventsAfterReportingPeriodAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of non-adjusting events after reporting period [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForIncomeTaxExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for income tax expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForIncomeTaxExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmountPlusFivePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair value of expected volatility amount plus five percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmountPlusFivePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value of Expected Volatility Amount Plus Five Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmountPlusFivePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected volatility +5%</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SignificantInvestmentsInSubsidiariesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsidiaries [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of transactions between related parties [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AttributionOfExpensesByNatureToTheirFunctionDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Attribution of expenses by nature to their function [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">European Investment Bank Loan Tranche B.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanTrancheBMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">European Investment Bank Loan - Tranche B [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigation_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision for tax litigation.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigation_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision For Tax Litigation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigation_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Provision for tax litigation, Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigation_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Provision for tax litigation, Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigation_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for tax litigation, Biginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNonadjustingEventsAfterReportingPeriodLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of non-adjusting events after reporting period [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BpifranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Bpifrance.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BpifranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Bpifrance [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BpifranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">BPI [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits other comprehensive income current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for termination benefits other comprehensive income current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProportionOfOwnershipInterestInSubsidiary_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proportion of ownership interest in subsidiary</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProportionOfOwnershipInterestInSubsidiary_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Ownership interest in subsidiary</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProportionOfOwnershipInterestInSubsidiary_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Ownership interest</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MilestonePayment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Milestone Payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MilestonePayment_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Milestone payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MilestonePayment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Milestone payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Revenue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Revenue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">External revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Revenue_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Revenue_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AllocationOfPriorPeriodGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Allocation of prior period gain (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AllocationOfPriorPeriodGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Allocation Of Prior Period Gain (Loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AllocationOfPriorPeriodGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Allocation of prior period loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AllocationOfPriorPeriodGainLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Standalone statutory loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The number of additional potential shares due to change in conversation ratio of stock options outstanding in share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Additional Shares Due To Change In Conversation Ratio Share Based Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option outstanding, change in conversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialAssetsAndLiabilitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of financial assets and liabilities table.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialAssetsAndLiabilitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Financial Assets And Liabilities [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialAssetsAndLiabilitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure Of Financial Assets And Liabilities [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Commercial litigation amounts used during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commercial Litigation Amounts Used During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commercial litigation, Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfAccountingPolicyForSegmentReportingExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description of accounting policy for segment reporting [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfAccountingPolicyForSegmentReportingExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Segment reporting</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash flows from (used in) operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/netLabel">Net cash flows from (used in) operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net cash used in operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanTrancheAMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">European Investment Bank Loan Tranche A.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanTrancheAMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">European Investment Bank Loan - Tranche A [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Liabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Liabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Liabilities at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Liabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Liabilities at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Liabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Liabilities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Liabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">TOTAL LIABILITIES</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredExpensesAndOtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Deferred expenses and other current assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredExpensesAndOtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred Expenses And Other Current Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredExpensesAndOtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred expenses and other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherOperatingExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other operating expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherOperatingExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Operating Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherOperatingExpenses_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other operating expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughNetExchangeDifferencesOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through net exchange differences, other provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughNetExchangeDifferencesOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non Current provisions other comprehensive income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Current provisions other comprehensive income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfScopeOfConsolidationAndNonConsolidatedEntitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of Scope of consolidation and non-consolidated entities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfScopeOfConsolidationAndNonConsolidatedEntitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Scope Of Consolidation and Non-Consolidated Entities [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TransactionCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Transaction costs.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TransactionCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Transaction Costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TransactionCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Transaction costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TransactionCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Transaction costs disbursed in cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProvisionsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits other comprehensive income Non-current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for termination benefits other comprehensive income Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Impairment loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ImpairmentLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Impairment of assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConvertibleNotesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Convertible Notes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConvertibleNotesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Convertible Notes [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of share options change in conversion ratios in sharebased payment arrangement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Share Options Change In Conversion Ratios In Sharebased Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option outstanding, change in conversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfOperatingAndReportableSegments_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of operating and reportable segments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfOperatingAndReportableSegments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of Operating and Reportable Segments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfOperatingAndReportableSegments_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of operating and reportable segments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CarryingAmountAccumulatedDepreciationAmortisationAndImpairmentAndGrossCarryingAmountDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Carrying amount, accumulated depreciation, amortisation and impairment and gross carrying amount [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CarryingAmountAccumulatedDepreciationAmortisationAndImpairmentAndGrossCarryingAmountDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Carrying amount, accumulated depreciation, amortisation and impairment and gross carrying amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialAssetsAndCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current financial assets and cash and cash equivalent.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialAssetsAndCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Financial Assets And Cash And Cash Equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialAssetsAndCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Current financial assets and cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentDeferredIncomeIncludingCurrentContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current deferred income including current contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentDeferredIncomeIncludingCurrentContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred income and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentDeferredIncomeIncludingCurrentContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total Deferred revenue and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentDeferredIncomeIncludingCurrentContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Deferred revenues and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdditionsOtherThanThroughBusinessCombinationsPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Additions other than through business combinations, property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdditionsOtherThanThroughBusinessCombinationsPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MiscellaneousOtherOperatingExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Miscellaneous other operating expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MiscellaneousOtherOperatingExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other operating expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ThresholdPercentageOfOwnershipInOutstandingCommonStockToEnactIndemnificationAgreement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Threshold percentage of ownership in outstanding common stock to enact indemnification agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ThresholdPercentageOfOwnershipInOutstandingCommonStockToEnactIndemnificationAgreement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Threshold Percentage Of Ownership In Outstanding Common Stock To Enact Indemnification Agreement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ThresholdPercentageOfOwnershipInOutstandingCommonStockToEnactIndemnificationAgreement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Threshold percentage of ownership in outstanding common stock to enact indemnification agreement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_AmendmentFlag_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amendment Flag</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_AmendmentFlag_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amendment Flag</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncomeLossMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Income loss.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncomeLossMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income (loss) [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfShareCapitalReservesAndOtherEquityInterestExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of share capital, reserves and other equity interest [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfShareCapitalReservesAndOtherEquityInterestExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share capital and premium related to the share capitals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfFairMarketValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Percentage of fair market value.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfFairMarketValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Percentage Of Fair Market Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfFairMarketValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Percentage of market value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information about property, plant and equipment [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of detailed information about property, plant and equipment [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestExpenseForFinancialLiabilitiesNotAtFairValueThroughProfitOrLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest expense for financial liabilities not at fair value through profit or loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestExpenseForFinancialLiabilitiesNotAtFairValueThroughProfitOrLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest on financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestExpenseForFinancialLiabilitiesNotAtFairValueThroughProfitOrLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Interest on financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MajorShareholdersAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Major Shareholders [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MajorShareholdersAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Major shareholders.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BorrowingsByNameDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Borrowings by name [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfIntangibleAssetsAndGoodwillAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of intangible assets and goodwill [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfIntangibleAssetsAndGoodwillAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Classes of intangible assets and goodwill [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOtherEquityInstrumentsForfeitedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of other equity instruments forfeited in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOtherEquityInstrumentsForfeitedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Option outstanding, forfeited, cancelled or expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfRelatedPartiesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Categories of related parties [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="stpr_NC_lbl" xlink:role="http://www.xbrl.org/2003/role/label">NORTH CAROLINA</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="stpr_NC_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Raleigh, North Carolina [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementPaymentReallocated_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Collaboration Agreement Payment Reallocated.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementPaymentReallocated_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Collaboration Agreement Payment Reallocated</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementPaymentReallocated_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Collaboration agreement payment reallocated</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MajorCustomersAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Major customers [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentRestrictedCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current restricted cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentRestrictedCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Restricted cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentRestrictedCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Short term restricted cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightofuseAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Right-of-use assets [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightofuseAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Right-of-Use Asset</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromCollaborationAgreements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of revenue from collaboration agreements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromCollaborationAgreements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue From Collaboration Agreements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromCollaborationAgreements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Collaboration agreements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromCollaborationAgreements_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Collaboration agreements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromCollaborationAgreements_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Revenue from collaboration agreements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RetainedEarningsProfitLossForReportingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Retained earnings, profit (loss) for reporting period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RetainedEarningsProfitLossForReportingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageFairValueAtMeasurementDateShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average fair value at measurement date, share options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageFairValueAtMeasurementDateShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted-Average fair values of stock options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cellectis, Inc. [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cellectis Inc [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cellectis [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Cellectis, Inc. [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfOutstandingBalancesWithOtherMajorShareholdersExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of outstanding balances with other major shareholders explanatory [Table Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfOutstandingBalancesWithOtherMajorShareholdersExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of outstanding balances with other major shareholders explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfOutstandingBalancesWithOtherMajorShareholdersExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of outstanding balances with other major shareholders</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AmendmentAgreementOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Amendment agreement one.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AmendmentAgreementOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amendment Agreement One [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AmendmentAgreementOneMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amendment Agreement One [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughTransfersRightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through transfers, right-of-use assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughTransfersRightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Reclassification</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ValuationMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The method used to estimate the fair value of an asset or a liability.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ValuationMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Valuation Method</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ValuationMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Valuation method</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LaterThanFiveYearsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Later than five years [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LaterThanFiveYearsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">More than Five Years [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantsGrantDate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Warrants grant date.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantsGrantDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Warrants Grant Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantsGrantDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Grant date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Ordinary shares issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance, shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance, shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of shares issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total number of shares issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Number of shares to be issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProvisionUsedOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision used, other provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProvisionUsedOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Provision used, other provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProvisionUsedOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_UnobservableInputsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unobservable inputs [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromSaleOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Proceeds from sale of ordinary shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromSaleOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds From Sale Of Ordinary Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromSaleOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Proceeds from sale of ordinary shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfIncomeTaxExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of income tax [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfIncomeTaxExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Income Tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule disclosing information related to details of non-current financial assets and other non-current assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule Disclosing Information Related to Details of Non-current Financial Assets and Other Non-current Assets [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Non-current Financial Assets and other non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseDueToRevenueRecognitionContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The decrease in contract liability balances resulting from the transfer of goods or services to customers.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseDueToRevenueRecognitionContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Decrease due to Revenue Recognition, Contract Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseDueToRevenueRecognitionContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease due to revenue recognition</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeAndOtherCurrentReceivablesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trade and other current receivables [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentType_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Type</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentType_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Type</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightsPreferencesAndRestrictionsAttachingToClassOfShareCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Rights, preferences and restrictions attaching to class of share capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightsPreferencesAndRestrictionsAttachingToClassOfShareCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Conversion ratio</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightsPreferencesAndRestrictionsAttachingToClassOfShareCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Conversion ratio description</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StockOption1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Stock option.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StockOption1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Stock Option 1 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StockOption1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock options [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableForfeitedOrExpiredInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average exercise price of share options exercisable forfeited or expired in share based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableForfeitedOrExpiredInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Exercise Price Of Share Options Exercisable Forfeited Or Expired In Share Based Payment Arrangements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableForfeitedOrExpiredInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted- average exercise price per share, forfeited or expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableForfeitedOrExpiredInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Weighted- average exercise price per share, forfeited or expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash flows from (used in) investing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/netLabel">Net cash flows from (used in) investing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net cash from (used in) investing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfMaterialAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of material accounting policy information [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfMaterialAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accounting principles</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOtherCurrentLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of other current liabilities [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOtherCurrentLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCentralIndexKey_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Central Index Key</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityCentralIndexKey_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Central Index Key</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BottomOfRangeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Bottom of range [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BottomOfRangeMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Bottom of Range [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughChangesInForeignExchangeRatesContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The increase (decrease) in contract liability balances resulting from changes in foreign exchange rates.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughChangesInForeignExchangeRatesContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) Through Changes in Foreign Exchange Rates, Contract Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughChangesInForeignExchangeRatesContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revenue from positive foreign exchange impact, partially offset</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MiscellaneousOtherOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Miscellaneous other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MiscellaneousOtherOperatingIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CytoviaAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cytovia agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CytoviaAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cytovia Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CytoviaAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cytovia Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision for tax litigation additions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision For Tax Litigation Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for tax litigation, Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GeographicalAreasAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Geographical areas [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GeographicalAreasAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Geographical areas [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseInWorkingCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) in working capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseInWorkingCapital_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel">Change in working capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current financial assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Financial Assets [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentFinancialAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current Financial Assets [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Borrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Borrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Borrowings_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AggregateCreditFacility_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Aggregate credit facility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AggregateCreditFacility_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Aggregate credit facility.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementOneDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Agreement one.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementOneDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Agreement One [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfBasisOfConsolidationAndMaterialAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of basis of consolidation and material accounting policy information explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfBasisOfConsolidationAndMaterialAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Basis Of Consolidation And Material Accounting Policy Information Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfBasisOfConsolidationAndMaterialAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Basis for preparation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Collaboration agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Collaboration Agreement [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentPortionOfState-GuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current Portion of State-Guaranteed Loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentPortionOfState-GuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Portion of State-Guaranteed Loan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SignificantInvestmentsInAssociatesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Associates [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits non-current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Termination Benefits Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Non current provisions Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Non current provisions beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OperatingExpenseAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Operating expense.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OperatingExpenseAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Operating Expense [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OperatingExpenseAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Operating expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RetainedEarningsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Retained earnings [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RetainedEarningsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retained Earnings (Deficit) [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DepreciationAmortisationAndImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Depreciation, amortisation and impairment loss (reversal of impairment loss) recognised in profit or loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DepreciationAmortisationAndImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total depreciation, amortisation and impairment loss (reversal of impairment loss) recognised in profit or loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DepreciationAmortisationAndImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Depreciation &amp; impairment expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DepreciationAmortisationAndImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Depreciation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatility_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The expected volatility of the share price used to calculate the fair value of the share options granted. Expected volatility is a measure of the amount by which a price is expected to fluctuate during a period. The measure of volatility used in option pricing models is the annualized standard deviation of the continuously compounded rates of return on the share over a period of time.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatility_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected Volatility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfFinancialAssetsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Categories of financial assets [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialLiabilitiesAndLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total Financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialLiabilitiesAndLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial Liabilities And Lease Debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialLiabilitiesAndLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Financial liabilities and lease debts.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsForfeited_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The weighted average fair value at the measurement date of other equity instruments (ie other than share options) expired or forfeited in a share-based payment arrangement. [Refer: Weighted average [member]"</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsForfeited_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Fair Value At Measurement Date Other Equity Instruments Forfeited</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsForfeited_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average exercise price per share, Cancelled</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ShareIssuancePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Share issuance price.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ShareIssuancePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share Issuance Price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ShareIssuancePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share issuance price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Receivables1Abstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Receivables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Receivables1Abstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Receivables1 [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Employees.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Employees [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TrancheAWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Tranche A Warrants.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TrancheAWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Tranche A Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RelatedPartyTransactionsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Related party transactions [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_CurrentFiscalYearEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Fiscal Year End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_CurrentFiscalYearEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current Fiscal Year End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentAssetsOtherThanAssetsOrDisposalGroupsClassifiedAsHeldForSaleOrAsHeldForDistributionToOwners_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current assets other than non-current assets or disposal groups classified as held for sale or as held for distribution to owners</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentAssetsOtherThanAssetsOrDisposalGroupsClassifiedAsHeldForSaleOrAsHeldForDistributionToOwners_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInterestsInConsolidationAndNonConsolidatedEntitiesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of interests in consolidation and non-consolidated entities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInterestsInConsolidationAndNonConsolidatedEntitiesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of interests in Consolidation and Non-Consolidated Entities [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInterestsInConsolidationAndNonConsolidatedEntitiesTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Scope of consolidation and non-consolidated entities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherOperatingIncome1_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherOperatingIncome1_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Operating Income1</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherOperatingIncome1_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInInterestIncomeFromCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase Decrease in interest income from cash, cash equivalents and financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInInterestIncomeFromCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in interest income from cash, cash equivalents and financial assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInInterestIncomeFromCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase (decrease) in interest income earned on cash, cash equivalents and financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AstraZenecaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Astra Zeneca.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AstraZenecaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Astra Zeneca [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AstraZenecaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">AstraZeneca [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseByNatureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expenses by nature [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseByNatureAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Operating expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherNoncurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other non-current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherNoncurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityInvestmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity investments [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfImpairmentLossAndReversalOfImpairmentLossAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of impairment loss and reversal of impairment loss [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TypesOfFinancialLiabilitiesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of financial liabilities [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInPersonnelExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase in personnel expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInPersonnelExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase In Personnel Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInPersonnelExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in personnel expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherNonCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other non-current financial liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherNonCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other non-current financial liabilities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherNonCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other Non-Current Financial Liabilities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Warrants [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="srt_StatementGeographicalAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Geographical [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassOfWarrantsOrRightAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Class Of Warrants Or Right [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdditionalProvisionsOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Additional provisions, other provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdditionalProvisionsOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdditionalProvisionsOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total additional provisions, other provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementTwoAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Agreement two</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementTwoAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Agreement Two [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenueAndContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Adjustments for increase (decrease) in deferred revenue and contract liabilities to reconcile profit (loss) to net cash flows provided by (used in) operating activities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenueAndContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments For Increase Decrease In Deferred Revenue And Contract Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenueAndContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease in deferred revenues and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceIncomeCost_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finance income (cost)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceIncomeCost_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net financial gain (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceIncomeCost_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net Financial gain (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceIncomeCost_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Net Financial gain (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NonadjustingEventsAfterReportingPeriodAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-adjusting events after reporting period [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTradeAndOtherReceivablesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of trade and other receivables [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTradeAndOtherReceivablesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Trade Receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueAndOtherIncomeExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of revenue and other income explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueAndOtherIncomeExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Revenue And Other Income Explanatory [TableTextBlock]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueAndOtherIncomeExplanatoryTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revenues By Country of Origin and Other Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfFinancialLiabilitiesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of financial liabilities [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfExpectedImpactOfInitialApplicationOfNewStandardsOrInterpretationsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of expected impact of initial application of new standards or interpretations [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfExpectedImpactOfInitialApplicationOfNewStandardsOrInterpretationsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of changes in accounting estimates [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharePriceWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Share price warrants.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharePriceWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share Price Warrants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharePriceWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ShorttermDepositsNotClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-term deposits, not classified as cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ShorttermDepositsNotClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current lease debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current lease debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current Lease Debts [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of Provisions for employee litigation and severance additions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for employee litigation and severance additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Employee litigation and severance, Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_JointResearchAndCollaborationAgreementInitialInvestmentAgreementSubsequentInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Joint research and collaboration agreement, initial investment agreement, subsequent investment agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_JointResearchAndCollaborationAgreementInitialInvestmentAgreementSubsequentInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Joint Research And Collaboration Agreement Initial Investment Agreement Subsequent Investment Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_JointResearchAndCollaborationAgreementInitialInvestmentAgreementSubsequentInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">AZ JRCA, IIA and SIA [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total non-current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair value of warrants.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value of warrants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Fair value of pre funded warrants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfDetailedInformationAboutFinancialInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information about financial instruments [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfDetailedInformationAboutFinancialInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial assets and liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreeementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Agreement Axis and License.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreeementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Agreeement [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfLiabilitiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of liabilities [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestPaidClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest paid, classified as financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestPaidClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestPaidClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Interest paid</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestPaidClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Interest paid on financial debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsForfeitedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average exercise price of share options forfeited in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsForfeitedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Weighted average exercise price per share, cancelled, forfeited or expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsForfeitedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average exercise price per share, forfeited or expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RangeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Range [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RangeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Range [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTaxFromContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other comprehensive income that will not be reclassified to profit or loss net of tax from continuing operations.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTaxFromContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Comprehensive Income That Will Not Be Reclassified To Profit Or Loss Net Of Tax From Continuing Operations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTaxFromContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other comprehensive income (loss) that will not be reclassified subsequently to income or loss from continued operations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfBasisOfPreparationOfFinancialStatementsAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Basis for preparation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfBasisOfPreparationOfFinancialStatementsAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of basis of preparation of financial statements accounting policy Information explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfBasisOfPreparationOfFinancialStatementsAccountingPolicyInformationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The disclosure of the basis used for the preparation of the financial statements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOffsettingOfFinancialLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of offsetting of financial liabilities [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOffsettingOfFinancialLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of offsetting of financial liabilities [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOffsettingOfFinancialLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Disclosure of offsetting of financial liabilities [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfExercisableShareOptionsExercisedInShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option exercisable, exercised</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfExercisableShareOptionsExercisedInShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of exercisable share options exercised in share based payment arrangement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfExercisableShareOptionsExercisedInShareBasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Exercisable Share Options Exercised In Share Based Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Option Outstanding, exercised</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Shares, Vested</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Forfeited or Expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Warrants outstanding, exercised</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Option outstanding, exercised</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInInvestingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash flows from (used in) investing activities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInInvestingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash flows from investment activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharesEntitlementPerOption_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Shares entitlement per option.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharesEntitlementPerOption_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Shares Entitlement per Option</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharesEntitlementPerOption_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share entitlement per option</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SegmentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Segments [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherSubsidiesAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">other subsidies amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherSubsidiesAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Subsidies Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherSubsidiesAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other subsidies and other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for decrease (increase) in trade and other receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease (increase) in trade receivables and other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average exercise price of share options exercisable in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Weighted- average exercise price per share, ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Weighted- average exercise price per share, beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RemeasurementOfTheContractualCashFlowsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Remeasurement of the contractual cash flows [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RemeasurementOfTheContractualCashFlowsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Remeasurement of the contractual cash flows.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RemeasurementOfTheContractualCashFlowsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Remeasurement of the Contractual Cash Flows [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeAndOtherReceivablesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trade and other receivables [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Profit (loss), attributable to ordinary equity holders of parent entity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Profit (loss), attributable to ordinary equity holders of parent entity, used in calculating basic earnings per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net loss attributable to shareholders of Cellectis ($ in thousands)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of financial liabilities [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CalyxtIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Calyxt Inc.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CalyxtIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Calyxt Inc [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CalyxtIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Calyxt Inc. [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestReceivedClassifiedAsOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest received, classified as operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestReceivedClassifiedAsOperatingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial liabilities, at fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Fair value of financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of terms and conditions of share-based payment arrangement [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of terms and conditions of share-based payment arrangement [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfSharesEntitledPerOption_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of shares entitled per option.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfSharesEntitledPerOption_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Shares Entitled Per Option</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfSharesEntitledPerOption_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share entitlement per option</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLoansReceivedAndCurrentPortionOfNoncurrentLoansReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current loans received and current portion of non-current loans received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLoansReceivedAndCurrentPortionOfNoncurrentLoansReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current liability of loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLoansReceivedAndCurrentPortionOfNoncurrentLoansReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Loan outstanding balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfFinancialLiabilitiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of financial liabilities [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfFinancialLiabilitiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Classes of financial liabilities [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfInstrumentsOtherEquityInstrumentsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of other equity instruments granted in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfInstrumentsOtherEquityInstrumentsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfInstrumentsOtherEquityInstrumentsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Option outstanding, granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EarningsPerShareAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings per share [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EarningsPerShareAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Basic / Diluted net income (loss) per share attributable to shareholders of Cellectis</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseAgreementTerm_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Lease agreement term.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseAgreementTerm_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Lease Agreement Term</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseAgreementTerm_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Lease agreement term</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of current financial assets and cash and cash equivalents.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Current Financial Assets And Cash And Cash Equivalents [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of current financial assets and cash and cash equivalents [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNumberAndWeightedAverageRemainingContractualLifeOfOutstandingShareOptionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of number and weighted average remaining contractual life of outstanding share options [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNumberAndWeightedAverageRemainingContractualLifeOfOutstandingShareOptionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Information on Stock Option Activity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for retirement indemnities amounts used during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Retirement Indemnities Amounts Used During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retirement indemnities , Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInTradeReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase decrease in trade receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInTradeReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in trade receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInTradeReceivables_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Decrease in trade receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutAssumptionsUsedAndValuationResultsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of information about assumptions used and valuation results.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutAssumptionsUsedAndValuationResultsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of information about assumptions used and valuation results [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutAssumptionsUsedAndValuationResultsTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Assumptions Used and Estimated Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_UnobservableInputsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unobservable inputs [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberOfOutstandingOptionWeightedAverageExercisePriceAndWeightedAverageRemainingContractualLifeExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Number Of Outstanding Option Weighted Average Exercise Price and Weighted Average Remaining Contractual Life Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberOfOutstandingOptionWeightedAverageExercisePriceAndWeightedAverageRemainingContractualLifeExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of number of outstanding option weighted average exercise price and weighted average remaining contractual life explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberOfOutstandingOptionWeightedAverageExercisePriceAndWeightedAverageRemainingContractualLifeExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Information on Stock Option Activity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfBreakdownOfRightOfUseAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Schedule of Breakdown Of Right Of Use Assets [Abstract].</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ScheduleOfBreakdownOfRightOfUseAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Schedule of Breakdown Of Right Of Use Assets [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of property, plant and equipment [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComprehensiveIncomeAttributableToOwnersOfParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Comprehensive income, attributable to owners of parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComprehensiveIncomeAttributableToOwnersOfParent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Attributable to shareholders of Cellectis</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComprehensiveIncomeAttributableToOwnersOfParent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total comprehensive income, attributable to owners of parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForFinanceIncomeCost_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for finance income (cost)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForFinanceIncomeCost_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Net financial loss (gain)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfDisaggregationOfRevenueFromContractsWithCustomersExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of disaggregation of revenue from contracts with customers [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfDisaggregationOfRevenueFromContractsWithCustomersExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revenues by Nature</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Consolidated operations.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Consolidated operations [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cellectis.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cellectis [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cellectis [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Cellectis [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentDerivativeFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current derivative financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentDerivativeFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Derivatives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExercisePriceShareOptionsGranted2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Exercise price, share options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExercisePriceShareOptionsGranted2019_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Exercise price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfBasisOfConsolidationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of basis of consolidation [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfBasisOfConsolidationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Information concerning the Group's Consolidated Operations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfBasisOfConsolidationExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Scope of consolidation and non-consolidated entities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfDetailedInformationAboutPropertyPlantAndEquipmentExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information about property, plant and equipment [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfDetailedInformationAboutPropertyPlantAndEquipmentExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Details of Property, Plant and Equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfImpairmentOfAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of impairment of assets [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfImpairmentOfAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Impairment tests</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInFinancialIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase In Financial Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInFinancialIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase in financial income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInFinancialIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in financial income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OptionVestingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Option vesting period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OptionVestingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Option Vesting Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OptionVestingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Vesting period, years</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseOptionToExtendLeaseAgreement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Lease option to extend lease agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseOptionToExtendLeaseAgreement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Lease Option To Extend Lease Agreement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseOptionToExtendLeaseAgreement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Lease option to extend lease agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseOptionToExtendLeaseAgreement_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Lease option to extend lease agreement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TermsOfRepayment_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Terms of repayment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TermsOfRepayment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Terms of Repayment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TermsOfRepayment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Terms of repayment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TypesOfWarrantsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Types of warrants [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TypesOfWarrantsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of warrants [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease in revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase Decrease Revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseRevenues_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase decrease revenues.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditFinancingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Research Tax Credit financing</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditFinancingMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Research Tax Credit Financing [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfReconciliationOfLiabilitiesArisingFromFinancingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of reconciliation of liabilities arising from financing activities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialInstitutionAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial Institution [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialLiabilitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of financial liabilities [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WagesAndSalaries_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Wages and salaries</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WagesAndSalaries_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Wages and salaries</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigations_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of commercial litigations.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigations_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commercial Litigations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigations_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Commercial litigation, Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigations_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Commercial litigation, Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromIssuingSharesAndOtherEquityInstrumentsNetOfTransactionCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds from issuing shares and other equity instruments net of transaction costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromIssuingSharesAndOtherEquityInstrumentsNetOfTransactionCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Proceeds from issuing shares and other equity instruments net of transaction costs.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromIssuingSharesAndOtherEquityInstrumentsNetOfTransactionCosts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Proceeds from the issuance of share capital and other equity instruments after deduction of transaction costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShare-BasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The number of additional potential shares due to change in conversation ratio of stock options outstanding in share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShare-BasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of Additional Shares Due to Change in Conversation Ratio, Share-based Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShare-BasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option outstanding, change in conversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAndLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity and liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAndLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of information about consolidated and non-consolidated structured entities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Information About Consolidated And Non-consolidated Structured Entities [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ForeignExchangeLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Foreign exchange loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ForeignExchangeLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Foreign exchange loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ForeignExchangeLoss_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Foreign exchange losses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ForeignExchangeLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Foreign exchange losses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Agreement Axis</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Agreement [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TypesOfAntidilutiveInstrumentsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of antidilutive instruments [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingOfFreeSharesAndStockOptionExercisesValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Vesting Of Free Shares And Stock Option Exercises Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingOfFreeSharesAndStockOptionExercisesValue_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The increase (decrease) in shareholders' equity through the issue of equity instruments resulting from the vesting of free shares and the exercises of stock-options granted to employees and directors in share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VestingOfFreeSharesAndStockOptionExercisesValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Exercise of share warrants, employee warrants, stock-options and free-shares vesting, amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finance income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinanceIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Financial income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentInformationLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Information [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForSharebasedPayments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for share-based payments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForSharebasedPayments_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expenses related to share-based payments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForSharebasedPayments_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Adjustments for share-based payments, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityLessFivePercentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expected volatility less five percent.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityLessFivePercentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected Volatility Less Five Percent [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityLessFivePercentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected volatility -5% [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non-current financial liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current financial liabilities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other non current financial liabilities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndGrantDateFairValueOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Number and Grant Date Fair Value of Other Equity Instruments Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndGrantDateFairValueOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The number of outstanding equity instruments, other than share options, granded in share-based payment arrangements, and the related weighted average fair value at the measurement date.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndGrantDateFairValueOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number and Weighted Average Fair Value at Measurement Date, Other Equity Instruments Granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantExpirationDate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Warrant expiration date.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantExpirationDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Warrant Expiration Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WarrantExpirationDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expiration date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SignificantUnobservableInputLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Significant unobservable input, liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SignificantUnobservableInputLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Percentage of grant and refundable advance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementUpfrontPaymentReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Collaboration agreement upfront payment received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementUpfrontPaymentReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Collaboration Agreement Upfront Payment Received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementUpfrontPaymentReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Collaboration agreement, upfront payment received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Non current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for retirement indemnities other comprehensive income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Retirement Indemnities Other Comprehensive Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retirement Indemnities , OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfDebtRepaymentTerms_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Percentage of debt repayment terms</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfDebtRepaymentTerms_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Percentage of debt repayment terms</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RiskFreeInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The risk-free rate represents the interest an investor would expect from an absolutely risk-free investment over a specified period of time.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RiskFreeInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Risk Free Interest Rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RiskFreeInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Risk-free interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RiskFreeInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Risk free rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other comprehensive income, before tax, gains (losses) on remeasurements of defined benefit plans</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total other comprehensive income, before tax, gains (losses) on remeasurements of defined benefit plans</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Actuarial gains (losses)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for retirement indemnities additions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Retirement Indemnities Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retirement indemnities , Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClinicalAndRdAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Clinical And Rd Agreements Member</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClinicalAndRdAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Clinical And RD Agreements [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClinicalAndRdAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Clinical &amp; Research and Development agreements [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredIncomeIncludingContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred income including contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredIncomeIncludingContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred income and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredIncomeIncludingContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total deferred income and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfShareCapitalDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of share capital [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LongtermDeposits_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Long-term deposits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LongtermDeposits_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LongtermDeposits_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deposit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CompanySharePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The fair value of the Company's common shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CompanySharePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Company share price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CompanySharePrice_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DefinedBenefitPlansDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Defined benefit plans [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalUpfrontPayments_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Total upfront payments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalUpfrontPayments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Total upfront payments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfSharebasedPaymentArrangementsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of share-based payment arrangements [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfSharebasedPaymentArrangementsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-cash stock-based compensation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseRemainingTerm_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Lease remaining term.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseRemainingTerm_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Lease Remaining Term</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseRemainingTerm_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Lease remaining period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfProvisionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of provisions [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfProvisionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of terms and conditions of share-based payment arrangement [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseFromSharebasedPaymentTransactionsWithEmployees_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expense from share-based payment transactions with employees</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseFromSharebasedPaymentTransactionsWithEmployees_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share based payment expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseFromSharebasedPaymentTransactionsWithEmployees_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Share-based compensation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseFromSharebasedPaymentTransactionsWithEmployees_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Non-cash stock based compensation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other provision for charges during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Provision For Charges During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other provision for charges, During the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ReserveOfExchangeDifferencesOnTranslationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reserve of exchange differences on translation [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ReserveOfExchangeDifferencesOnTranslationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Currency Translation Adjustment [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SocialSecurityContributionsOnStockOptionGrants_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Social security contributions on stock option grants.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SocialSecurityContributionsOnStockOptionGrants_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Social Security Contributions On Stock Option Grants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SocialSecurityContributionsOnStockOptionGrants_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Social charges on stock option grants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SocialSecurityContributionsOnStockOptionGrants_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Social charges on stock option grants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfShareCapitalAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of share capital [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfShareCapitalAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Classes of share capital [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TypesOfSharebasedPaymentArrangementsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of share-based payment arrangements [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VariableConsiderationAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Variable consideration amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VariableConsiderationAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Variable consideration amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmountLessFivePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair value of expected volatility amount less five percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmountLessFivePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value of Expected Volatility Amount Less Five Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfExpectedVolatilityAmountLessFivePercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected volatility -5%</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsDuringThePeriodNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits during the period non-current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsDuringThePeriodNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Termination Benefits During The Period Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsDuringThePeriodNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions Amounts used during period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MajorCustomersDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Major customers [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialAssetsAndLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of financial assets and liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialAssetsAndLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Financial Assets And Liabilities [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialAssetsAndLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of financial assets and liabilities [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase (decrease) in non-current research tax credit receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) in non-current research tax credit receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in non-current research tax credit receivables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Other financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfFinancingTaxReceivableRelatedToResearchTaxCredit_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Percentage of financing tax receivable related to research tax credit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfFinancingTaxReceivableRelatedToResearchTaxCredit_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The percentage of the certain Research Tax Credit Receivables subject to a prefinancing.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PercentageOfFinancingTaxReceivableRelatedToResearchTaxCredit_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financing tax receivable percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestExpenseOnLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest expense on lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestExpenseOnLeaseLiabilities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Interest on lease liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNonCurrentFinancialAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The enitre disclosure of non-current financial assets explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNonCurrentFinancialAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Non-current Financial Assets Explanatory [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNonCurrentFinancialAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherExpenseByNature_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other expenses, by nature</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherExpenseByNature_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherExpenseByNature_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherExpenseByNature_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Other expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAttributableToOwnersOfParent_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAttributableToOwnersOfParent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity attributable to owners of parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAttributableToOwnersOfParent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total equity attributable to owners of parent</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAttributableToOwnersOfParent_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CapitalCommitmentsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Capital commitments [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Deposit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenuesAndContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Adjustments for increase decrease in deferred revenues and contract liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenuesAndContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for increase decrease in deferred revenues and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenuesAndContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in deferred revenues and contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialFairValueOfLoan_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Initial fair value of loan.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialFairValueOfLoan_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Initial Fair Value Of Loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialFairValueOfLoan_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Initial fair value of the loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision for tax litigation member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision For Tax Litigation [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for tax litigation [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInSellingGeneralAndAdministrativeExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase In Selling General And Administrative Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInSellingGeneralAndAdministrativeExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase In Selling General And Administrative Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInSellingGeneralAndAdministrativeExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in selling, general and administrative expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisBiologicsIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cellectis biologics, Inc.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisBiologicsIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cellectis Biologics Inc [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CellectisBiologicsIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cellectis Biologics, Inc. [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LicenseAndCollaborationAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">License and Collaboration Agreements [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LicenseAndCollaborationAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">License and Collaboration Agreements [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LicenseAndCollaborationAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">License and Collaboration Agreements [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherNoncurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other non-current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherNoncurrentFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SellingGeneralAndAdministrativeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Selling, general and administrative expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SellingGeneralAndAdministrativeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total selling, general and administrative expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SellingGeneralAndAdministrativeExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Selling, general and administrative expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SellingGeneralAndAdministrativeExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel">Total selling, general and administrative expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DerivativesByNameAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Derivatives by name.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DerivativesByNameAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Derivatives By Name [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SharePremium_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share premium</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SharePremium_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Premiums related to the share capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfEventsAfterReportingPeriodExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of events after reporting period [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfEventsAfterReportingPeriodExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Subsequent events</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisableInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of share options exercisable in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisableInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Option exercisable, ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsExercisableInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Option exercisable, beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceReversal_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of provisions for employee litigation and severance reversal.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceReversal_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for employee litigation and severance reversal</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceReversal_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Employee litigation and severance, Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FixturesFittingsAndOtherEquipmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fixtures, fittings and other equipment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FixturesFittingsAndOtherEquipmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fixtures, Fittings and Other Equipment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOutstandingShareOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of share options outstanding in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOutstandingShareOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Option outstanding, ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOutstandingShareOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Option outstanding, beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expected volatility warrants.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected Volatility Warrants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected volatility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationConcerningGroupsConsolidatedOperartionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of Information concerning groups consolidated operartions explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationConcerningGroupsConsolidatedOperartionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Information concerning Groups Consolidated Operartions Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationConcerningGroupsConsolidatedOperartionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Information concerning the Group's Consolidated Operations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentValueAddedTaxReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current value added tax receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentValueAddedTaxReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">VAT receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TaxAndSocialReceivablesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Tax (other than income tax and value added tax) and social receivables current.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TaxAndSocialReceivablesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Tax and social receivables current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TaxAndSocialReceivablesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Tax and social receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ShareOptionsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share options [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ShareOptionsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock options [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other current financial liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherCurrentFinancialLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Current Financial Liabilities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfChangesInAccountingEstimatesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of changes in accounting estimates [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LevelsOfFairValueHierarchyAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Levels of fair value hierarchy [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionForCurrentProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Addition for current provision.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionForCurrentProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Addition For Current Provision</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionForCurrentProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provision additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfWarrantGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of warrant granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfWarrantGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MeasurementDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Measurement [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioExercisableOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The number of additional potential shares due to change in conversation ratio of exercisable options in share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioExercisableOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of Additional Shares Due to Change in Conversation Ratio, Exercisable Options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioExercisableOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option exercisable, change in coversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AverageLifeOfOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Average life of options.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AverageLifeOfOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Average Life of Options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AverageLifeOfOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Average life of options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Termination Benefits current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Current provisions Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Current provisions beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrincipalMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Principal.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrincipalMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Principal [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassesOfCommitmentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Classes of commitments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassesOfCommitmentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of commitments [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfClassesOfShareCapitalLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of classes of share capital [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfClassesOfShareCapitalLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of classes of share capital [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LaterThanOneYearAndNotLaterThanThreeYearsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Later than one year and not later than three years [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LaterThanOneYearAndNotLaterThanThreeYearsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">1-3 years [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsDuringThePeriodCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits during the period current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsDuringThePeriodCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Termination Benefits During The Period current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsDuringThePeriodCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions Amounts used during period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_StatementOfChangesInEquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of changes in equity [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Net income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Net income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Net loss for the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProfitLoss_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Net loss</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LicenceFeeIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Licence fee income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LicenceFeeIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Licenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ForeignExchangeGain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Foreign exchange gain</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ForeignExchangeGain_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Foreign exchange gains</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashOnHand_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash on hand</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashOnHand_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash and bank accounts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentPeriodEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Period End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentPeriodEndDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Period End Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentTaxLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current tax liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentTaxLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Income tax payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total other current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Other current financial assets (deposits)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DebtSecuritiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Debt securities [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SignificantInvestmentsInAssociatesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Associates [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfRelatedPartiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Categories of related parties [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfRelatedPartiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Categories of related parties [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinanceIncomeExpenseAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Finance income expense [abstract].</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinanceIncomeExpenseAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Finance income expense [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNonadjustingEventsAfterReportingPeriodTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of non-adjusting events after reporting period [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfTradeReceivablesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of trade receivables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfTradeReceivablesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of trade receivables [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsReversalsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits reversals non-current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsReversalsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Termination Benefits Reversals Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsReversalsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of detailed information about current financial assets and cash and cash equivalents explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Detailed Information About Current Financial Assets And Cash And Cash Equivalents Explanatory [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Current Financial Assets and Cash and Cash Equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Right-of-use assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Right-of-use&#160;assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Right-of-use assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredRevenueIncludingUpfrontPayment_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Deferred revenue including upfront payment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredRevenueIncludingUpfrontPayment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred Revenue Including Upfront Payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DeferredRevenueIncludingUpfrontPayment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred revenue including upfront payment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Commercial litigation.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commercial litigation [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commercial litigation [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesWithContingentFeaturesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial liabilities with contingent features [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">External other income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PersonnelExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Personnel expenses.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PersonnelExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Personnel Expenses [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PersonnelExpensesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Personnel Expenses [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssetsAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial assets, at fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssetsAtFairValue_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalCurrentFinancialLiabilitiesAndLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Total current financial liabilities and lease debts.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalCurrentFinancialLiabilitiesAndLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Total Current Financial Liabilities And Lease Debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalCurrentFinancialLiabilitiesAndLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total current financial liabilities and current lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalCurrentFinancialLiabilitiesAndLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current financial liabilities and current lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IssuedCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Issued capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IssuedCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total issued capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IssuedCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Share capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssetsOutsideScopeOfIFRS7Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial assets outside scope of IFRS 7, class [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InvesteeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Investee.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InvesteeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Investee [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The weighted average fair value at the measurement date of outstanding equity instruments other than share options. [Refer: Weighted average [member]].</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average fair value at measurement date other equity instruments outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Weighted average exercise price per share, ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Weighted average exercise price per share, beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxExpenseContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Income tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxExpenseContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Effective tax expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxExpenseContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total tax expense (income)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxExpenseContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Income tax</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeTaxExpenseContinuingOperations_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Tax income (expense)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Consolidated operations [line items].</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Consolidated operations [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ConsolidatedOperationsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Consolidated operations [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BPIRefundableAdvanceAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">BPI Refundable Advance Agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BPIRefundableAdvanceAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">BPI Refundable Advance Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PropertyPlantAndEquipmentAccumulatedDepreciationAmortisationAndImpairment_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Property, plant and equipment, accumulated depreciation, amortisation and impairment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PropertyPlantAndEquipmentAccumulatedDepreciationAmortisationAndImpairment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Property, plant and equipment, accumulated depreciation, amortisation and impairment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PropertyPlantAndEquipmentAccumulatedDepreciationAmortisationAndImpairment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accumulated depreciation and impairment at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseThroughFinancingCashFlowsInterestPaymentLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The decrease in liabilities arising from financing activities resulting from interest payments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseThroughFinancingCashFlowsInterestPaymentLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Decrease Through Financing Cash Flows (Interest Payment), Liabilities Arising from Financing Activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseThroughFinancingCashFlowsInterestPaymentLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest paid financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfScheduleOfOffBalanceSheetCommitmentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of schedule of off-balance sheet commitments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfScheduleOfOffBalanceSheetCommitmentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Schedule of Off-balance Sheet Commitments Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfScheduleOfOffBalanceSheetCommitmentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Schedule of Off-balance Sheet Commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RevenueAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Contract liabilities at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Contract liabilities at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred revenues</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure Of Number And Weighted Average Exercise Prices Of Share Options and awards [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Number And Weighted Average Exercise Prices Of Share Options and awards [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure Of Number And Weighted Average Exercise Prices Of Share Options and awards [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialLiabilityMaturity_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Financial liability maturity.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialLiabilityMaturity_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial Liability Maturity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FinancialLiabilityMaturity_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial liability maturity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TypesOfFinancialLiabilitiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of financial liabilities [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfImpairmentLossAndReversalOfImpairmentLossTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of impairment loss and reversal of impairment loss [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentPayables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other current payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentPayables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReversalOfCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Reversal of current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReversalOfCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reversal Of Current Provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReversalOfCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other comprehensive income, before tax, exchange differences on translation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Currency translation adjustment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other comprehensive income, before tax, exchange differences on translation of foreign operations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfFinancialAssetsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of financial assets [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LossesOnChangeInFairValueOfDerivatives_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Losses on change in fair value of derivatives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LossesOnChangeInFairValueOfDerivatives_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Losses on change in fair value of derivatives</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LossesOnChangeInFairValueOfDerivatives_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Loss on fair value measurement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfMaturitiesOfFinancialLiabilitiesExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Maturities Of Financial Liabilities Explanatory [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfMaturitiesOfFinancialLiabilitiesExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of maturities of financial liabilities explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfMaturitiesOfFinancialLiabilitiesExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Remaining contractual maturities of financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpectedDividendAsPercentageShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected dividend as percentage, share options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpectedDividendAsPercentageShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected dividends</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInFinancialIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Decrease in financial income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInFinancialIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Decrease In Financial Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInFinancialIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease in financial income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughTransfersPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through transfers, property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughTransfersPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Reclassification</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughTransfersPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Reclassification</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassOfWarrantsOrRightDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Class Of Warrants Or Right [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="stpr_NY_lbl" xlink:role="http://www.xbrl.org/2003/role/label">NEW YORK</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="stpr_NY_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">New York [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CibusIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cibus, Inc.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CibusIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cibus Inc [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsAdditionsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits additions Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsAdditionsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for termination benefits additions Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsAdditionsNoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfProvisionsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of other provisions [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfNoncurrentFinancialAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Categories of non-current financial assets [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfPresentationCurrencyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Description of presentation currency explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfPresentationCurrencyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description Of Presentation Currency Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfPresentationCurrencyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Currency of the financial statements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentSubsidiesReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of current grant receivables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentSubsidiesReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current subsidies receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentSubsidiesReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Subsidies receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityFileNumber_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity File Number</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FixedInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fixed interest rate.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FixedInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fixed Interest Rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FixedInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Annual rate of discounting</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average fair value at measurement date other equity instrument granted.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Fair Value At Measurement Date Other Equity Instrument Granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average exercise price per share, granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_CoverAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cover [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PurchasesAndExternalExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Purchases and external expenses.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PurchasesAndExternalExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Purchases And External Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PurchasesAndExternalExpenses_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Purchases and external expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeasedEquipmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Leased equipment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeasedEquipmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Leased Equipment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDeferredIncomeAndContractLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of deferred income and contract liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDeferredIncomeAndContractLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Deferred Income and Contract Liabilities Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InvesteeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Investee.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InvesteeAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Investee [Axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_UnusedProvisionReversedOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unused provision reversed, other provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_UnusedProvisionReversedOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Unused provision reversed, other provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_UnusedProvisionReversedOtherProvisions_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Pension, Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfQuantitativeInformationAboutRightofuseAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of quantitative information about right-of-use assets [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNumberAndWeightedAverageExercisePricesOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Number of Shares Outstanding and Weighted Average Grant Date Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNumberAndWeightedAverageExercisePricesOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of number and weighted average exercise prices of other equity instruments [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Non-CurrentLeaseLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non-current Lease Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Non-CurrentLeaseLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current Lease Liabilities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Non-CurrentLeaseLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Non Current Lease Debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementsExtendedMaturityDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Agreements Extended Maturity Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementsExtendedMaturityDate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Agreements Extended Maturity Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AgreementsExtendedMaturityDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Agreements extended maturity date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Level1OfFairValueHierarchyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Level 1 of fair value hierarchy [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Level1OfFairValueHierarchyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Level 1 [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfRelatedPartyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of related party [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfRelatedPartyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Significant transactions with related parties</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfRelatedPartyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Related parties and other major shareholders</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current liabilities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentLiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CarryingAmountAccumulatedDepreciationAmortisationAndImpairmentAndGrossCarryingAmountAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Carrying amount, accumulated depreciation, amortisation and impairment and gross carrying amount [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CarryingAmountAccumulatedDepreciationAmortisationAndImpairmentAndGrossCarryingAmountAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Carrying amount, accumulated depreciation, amortisation and impairment and gross carrying amount [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfFinancialLiabilitiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Categories of financial liabilities [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfVestingRequirementsForSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description of vesting requirements for share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfVestingRequirementsForSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Vesting conditions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfVestingRequirementsForSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Vesting conditions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of financial assets [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of financial assets [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfInputsUsedInFairValueMeasurementLiabilitiesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The description of inputs used in the fair value measurement of liabilities. Inputs are the assumptions that market participants would use when pricing the liability, including assumptions about risk such as the risk inherent in a particular valuation technique used to measure fair value (such as a pricing model) and the risk inherent in the inputs to the valuation technique.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfInputsUsedInFairValueMeasurementLiabilitiesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description of inputs used in fair value measurement, liabilities [Table text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfInputsUsedInFairValueMeasurementLiabilitiesTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of assumptions and results of the warrant valuation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TradePayablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Trade payables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TradePayablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trade Payables [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TradePayablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade Payables [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of number and weighted average exercise prices of share options [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Information on Stock Option Activity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExecutiveOfficersAndChairmanOfBoardOfDirectorsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Executive Officers and Chairman of Board of Directors [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExecutiveOfficersAndChairmanOfBoardOfDirectorsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Executive officers and chairman of board of directors.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TextBlock1Abstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Text Block [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TextBlock1Abstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Text block1 [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TextBlock1Abstract_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Text block1 [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CounterpartiesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Counterparties [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of current financial assets and cash and cash equivalents explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of current financial assets and cash and cash equivalents explanatory [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current financial assets and Cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfEarningsPerShareExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of earnings per share [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfEarningsPerShareExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Earnings per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ITLicensingAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">IT Licensing agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ITLicensingAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">IT Licensing agreement [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ITLicensingAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">IT Licensing Agreements [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other provision for charges additions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Provision For Charges Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other provision for charges, Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfMethodOfSettlementForSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description of method of settlement for share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfMethodOfSettlementForSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Valuation method</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of shares outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Balance at end, Number of shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Balance at beginning, Number of shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfSharesOutstanding_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of shares outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsidiesReceivablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Subsidies receivables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsidiesReceivablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsidies receivables [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsidiesReceivablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Subsidies Receivables [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of terms and conditions of share-based payment arrangement [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of terms and conditions of share-based payment arrangement [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Assumptions and results of the warrants valuation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other current financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherCurrentFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision for tax litigation used during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision for Tax Litigation Used During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for tax litigation, Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtAmortisedCostCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial liabilities at amortised cost, category [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialLiabilitiesAtAmortisedCostCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial Liabilities at Amortised Cost, Category [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOtherCurrentAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of other current assets [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOtherCurrentAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Other Current Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughNetExchangeDifferencesPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through net exchange differences, property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughNetExchangeDifferencesPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Translation adjustments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial assets at fair value through profit or loss, category [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial Assets at Fair Value Through Profit or Loss, Category [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfOtherReceivablesPrepaymentsAndOtherCurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of other receivables, prepayments and other current asset.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfOtherReceivablesPrepaymentsAndOtherCurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Other Receivables Prepayments and Other Current Assets [Abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutProvisionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of detailed information about provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutProvisionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Detailed Information About Provisions [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutProvisionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Details of Provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OptionLifeShareOptionGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The option life of share option granted.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OptionLifeShareOptionGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Option Life Share Option Granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OptionLifeShareOptionGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Option life, share option granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other provision for charges reversals.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Provision For Charges Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other provision for charges, Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non current provisions during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Current Provisions During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentProvisionsDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions Amounts used during period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfRiskFreeInterestRateShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Risk free interest rate, share options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfRiskFreeInterestRateShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Risk-free interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeSharesAndStockOptionExercises_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Exercise of share warrants, employee warrants, stock-options and free-shares vesting, shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeSharesAndStockOptionExercises_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase In Number Of Ordinary Shares Issued Due To Vesting Of Free Shares And Stock Option Exercises</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeSharesAndStockOptionExercises_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The increase in the number of ordinary shares issued due to vesting of free shares and exercise of stock options granted to employees and directors in share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Total non-current financial liabilities and non-current lease debts.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Total Non current Financial Liabilities And Non current Lease Debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Non-current financial liabilities and non-current lease debts, Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Non-current financial liabilities and non-current lease debts, Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Total non-current financial liabilities and non-current lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total non-current financial liabilities and non-current lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncomeStatementAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Profit or loss [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_StatementOfFinancialPositionAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of financial position [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrepaidExpensesAndOtherCurrentAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Prepaid expenses and other current assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrepaidExpensesAndOtherCurrentAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Prepaid Expenses and Other Current Assets [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrepaidExpensesAndOtherCurrentAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Prepaid expenses and other current assets [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SellingGeneralAndAdministrativeExpenses1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Selling general and administrative expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SellingGeneralAndAdministrativeExpenses1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Selling General And Administrative Expenses 1 [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SellingGeneralAndAdministrativeExpenses1Member_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Selling, General and Administrative Expenses [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current assets [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other comprehensive income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Other comprehensive income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total other comprehensive income (loss)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RestrictedStockUnitMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Restricted stock unit.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RestrictedStockUnitMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Restricted Stock Unit [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RestrictedStockUnitMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">RSU Calyxt 2017 [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfAssetsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of assets [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RetirementIndemnitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Retirement indemnities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RetirementIndemnitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Retirement Indemnities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RetirementIndemnitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retirement Indemnities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average exercise price of share options granted in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average exercise price per share, granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current provisions other comprehensive income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Provisions Other Comprehensive Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComponentsOfEquityAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Components of equity [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComponentsOfEquityAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Components of equity [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TypesOfAntidilutiveInstrumentsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of antidilutive instruments [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInResearchAndDevelopmentExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in research and development expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInResearchAndDevelopmentExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase in Research and Development Expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInResearchAndDevelopmentExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase in research and development expense.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForGainLossOnDisposalsPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for gain (loss) on disposals, property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForGainLossOnDisposalsPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Net loss (income) on disposals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash flows from (used in) operations before changes in working capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Operating cash flows before change in working capital</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BasicEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Basic earnings (loss) per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BasicEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total basic earnings (loss) per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BasicEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Basic net income (loss) attributable to shareholders of Cellectis, per share ($ /share)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BasicEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Basic net loss per share attributable to shareholders of Cellectis ($ /share)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInDepreciationAndAmortizationExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase In Depreciation And Amortization Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInDepreciationAndAmortizationExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase In Depreciation And Amortization Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInDepreciationAndAmortizationExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in depreciation and amortization expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AtFairValueMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">At fair value [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AtFairValueMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair Value [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for retirement indemnities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Retirement Indemnities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Retirement indemnities , Ending Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Retirement indemnities , Beginning Balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfDerivativeInstrumentsWarrantGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of derivative instruments warrant granted.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfDerivativeInstrumentsWarrantGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of Derivative Instruments Warrant Granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfDerivativeInstrumentsWarrantGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OfficeAndLaboratoryEquipmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Office and Laboratory equipment.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OfficeAndLaboratoryEquipmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Office and laboratory equipment [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReallocatedProceedsFromSaleOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Reallocated proceeds from sale of ordinary shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReallocatedProceedsFromSaleOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reallocated Proceeds From Sale Of Ordinary Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReallocatedProceedsFromSaleOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Reallocated proceeds from sale of ordinary shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageSharePriceShareOptionsGrantedPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The weighted average per share price used as input to the option pricing model to calculate the fair value of share options granted.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageSharePriceShareOptionsGrantedPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Share Price Share Options Granted Per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageSharePriceShareOptionsGrantedPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted-Average fair values of stock options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageSharePriceShareOptionsGrantedPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Weighted-Average fair values of warrants granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForRealizedForeignExchangeLossesGains_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Adjustments for realized foreign exchange losses gains.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForRealizedForeignExchangeLossesGains_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments For Realized Foreign Exchange Losses Gains</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForRealizedForeignExchangeLossesGains_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Realized foreign exchange gain (loss) related to operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfWarrantsIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of warrants issued.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfWarrantsIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number Of Warrants Issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfWarrantsIssued_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of warrants issued</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for depreciation and amortisation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amortization and depreciation</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Adjustments for depreciation and amortisation expense, Total</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AttributionOfExpensesByNatureToTheirFunctionAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Attribution of expenses by nature to their function [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutShareBasedPaymentAwardStockOptionsValuationAssumptionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Information About Share Based Payment Award Stock Options Valuation Assumptions Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutShareBasedPaymentAwardStockOptionsValuationAssumptionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, and (d) risk-free rate(s).</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutShareBasedPaymentAwardStockOptionsValuationAssumptionsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of assumptions Vesting Details</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Provisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Provisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Provisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Provisions_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current provisions during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Provisions During The Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentTradeReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current trade receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentTradeReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentTradeReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total net value of trade receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentTradeReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Total net value of trade receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialFairValueAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Initial fair value amount.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialFairValueAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Initial Fair Value Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialFairValueAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Initial fair value amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MaturityDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Maturity [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities arising from financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Financial liabilities and lease debts, Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Financial liabilities and lease debts, Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_UnderlyingStockPriceAtGrantDate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Share price used as input to the option pricing model to calculate the fair value of share options granted.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_UnderlyingStockPriceAtGrantDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Underlying Stock Price at Grant Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_UnderlyingStockPriceAtGrantDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Underlying stock price at grant date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeasedPremisesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Leased premises.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeasedPremisesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Leased Premises [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentFiscalYearFocus_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Fiscal Year Focus</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentFiscalYearFocus_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Fiscal Year Focus</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OrdinarySharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Ordinary shares [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OrdinarySharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share Capital Ordinary Shares [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OrdinarySharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Common Stock [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MaturityAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Maturity [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MaturityAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Maturity [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average exercise price of share options change in conversion ratios in sharebased payment arrangement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Exercise Price Of Share Options Change In Conversion Ratios In Sharebased Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted- average exercise price per share, Additional shares due to change in conversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpirationDate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expiration Date.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpirationDate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expiration Date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpirationDate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expiration date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentLeaseLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current Lease Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentLeaseLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Lease Liabilities [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentLeaseLiabilitiesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Current Lease Debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average number of ordinary shares outstanding</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average number of outstanding shares, used to calculate basic net result per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageShares_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Basic</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutDeferredIncomeAndContractLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of detailed information about deferred income and contract liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutDeferredIncomeAndContractLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Detailed Information About Deferred Income And Contract Liabilities Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutDeferredIncomeAndContractLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Details of Deferred Income and Contract Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonEmployeeWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non Employee Warrants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonEmployeeWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Employee Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonEmployeeWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non Employee Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GeographicalAreasDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Geographical areas [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfContingentLiabilitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of contingent liabilities [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) in cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">(Decrease) increase in cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2009/role/netLabel">Net increase (decrease) in cash and cash equivalents after effect of exchange rate changes</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Decrease in cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfExpensesByNatureExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of expenses by nature [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfExpensesByNatureExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Details of Operating Expenses by Nature</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of current financial assets and cash and cash equivalents.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Current Financial Assets and Cash and Cash Equivalents [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Current Financial Assets and Cash and Cash Equivalents [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Level3OfFairValueHierarchyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Level 3 of fair value hierarchy [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Level3OfFairValueHierarchyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Level 3 [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current liabilities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SignificantInvestmentsInSubsidiariesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsidiaries [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SignificantInvestmentsInSubsidiariesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Subsidiaries [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfLiabilitiesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of liabilities [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non current lease debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non current lease debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non Current Lease Debts [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GrossCarryingAmountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Gross carrying amount [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GrossCarryingAmountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Gross value [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_GrossCarryingAmountMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Gross Value [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssetsAtAmortisedCostCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial assets at amortised cost, category [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssetsAtAmortisedCostCategoryMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Financial Assets at Amortised Cost, Category [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOtherEquityInstrumentsExercisedOrVestedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of other equity instruments exercised or vested in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOtherEquityInstrumentsExercisedOrVestedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Option outstanding, exercised/vested</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VotingAgreementWithCibusMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Voting agreement with cibus.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VotingAgreementWithCibusMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Voting Agreement with Cibus [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_VotingAgreementWithCibusMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Voting Agreement with Cibus [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsequentInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Subsequent investment agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsequentInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsequent Investment Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsequentInvestmentAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Subsequent Investment Agreement (SIA) [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AverageEffectiveTaxRate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Average effective tax rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AverageEffectiveTaxRate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Effective tax rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AverageEffectiveTaxRate_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total average effective tax rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AverageEffectiveTaxRate_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Effective income tax rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average exercise price of share options exercised in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average exercise price per share, exercised</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Weighted average exercise price per share, exercised/vested</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestRateMeasurementInputMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Interest rate, measurement input [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_InterestRateMeasurementInputMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest Rate, Measurement Input [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharePriceOfWarrant_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Share price of warrant.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharePriceOfWarrant_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share Price Of Warrant</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharePriceOfWarrant_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share price (in euros)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SharePriceOfWarrant_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Share price</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherAdjustmentsForNoncashItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other adjustments for non-cash items</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherAdjustmentsForNoncashItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other non-cash items</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfFinancialAssetsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Categories of financial assets [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageGrantDateFairValueOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The disclosure of the number and weighted average grant date fair value of other equity instruments (i.e. other than share options) in share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageGrantDateFairValueOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of number and weighted average grant date fair value of other equity Instruments Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfNumberAndWeightedAverageGrantDateFairValueOfOtherEquityInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Number of Shares Outstanding and Weighted Average Grant Date Fair Value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CounterpartiesAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Counterparties [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFairValueOfFinancialInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of fair value of financial instruments [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFairValueOfFinancialInstrumentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Financial Assets and Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsForfeitedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of share options forfeited in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsForfeitedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Option outstanding, forfeited or expired</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision for tax litigation, Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision For Tax Litigation Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for tax litigation, Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipmentByOperatingLeaseStatusDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Property, plant and equipment by operating lease status [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Liabilities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">LIABILITIES</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInFinancingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash flows from (used in) financing activities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInFinancingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash flows from financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassAConvertiblePreferredSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Class A convertible preferred shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassAConvertiblePreferredSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Class A convertible preferred shares [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassAConvertiblePreferredSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">"Class A" Convertible Preferred Shares [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PreferenceSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Preference shares [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PreferenceSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Share Capital Preference Shares [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RangeDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Range [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_StatementOfChangesInEquityLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of changes in equity [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsReversalsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits reversals current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsReversalsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Termination Benefits Reversals current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsReversalsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrimeraTherapeuticsIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Primera therapeutics, Inc.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrimeraTherapeuticsIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Primera Therapeutics Inc [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrimeraTherapeuticsIncMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Primera Therapeutics, Inc. [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsGrantedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of share options granted in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsGrantedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of equity instruments granted in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfShareOptionsGrantedInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Option outstanding, granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RetainedEarningsExcludingProfitLossForReportingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Retained earnings, excluding profit (loss) for reporting period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RetainedEarningsExcludingProfitLossForReportingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Retained earnings (deficit)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedFinancialLiabilitiesAndLeaseDebtsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The entire disclosure in details of financial liabilities and lease debts.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedFinancialLiabilitiesAndLeaseDebtsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Detailed Financial Liabilities and Lease Debts Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedFinancialLiabilitiesAndLeaseDebtsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Detail of financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeReceivablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trade receivables [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeReceivablesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade Receivables [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average exercise price of share options exercisable granted in share based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Exercise Price Of Share Options Exercisable Granted In Share Based Payment Arrangements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted- average exercise price per share, granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other provision for charges.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Provision For Charges</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Other provision for charges, Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Other provision for charges, Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForCharges_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other provision for charges, Biginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfOtherProvisionsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of other provisions [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_DocumentInformationTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Document Information [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOtherProvisionsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of other provisions [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision for tax litigation other comprehensive income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision For Tax Litigation Other Comprehensive Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionForTaxLitigationOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Provision for tax litigation, OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information about property, plant and equipment [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CalyxtMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Calyxt.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CalyxtMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Calyxt [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CalyxtMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Calyxt [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfContingentLiabilitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of contingent liabilities [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalCurrentFinancialLiabilitiesAndCurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Total Current Financial Liabilities and Current Lease Debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalCurrentFinancialLiabilitiesAndCurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Total Current Financial Liabilities and Current Lease Debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Current provisions Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Current provisions beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipmentByOperatingLeaseStatusAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Property, plant and equipment by operating lease status [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PropertyPlantAndEquipmentByOperatingLeaseStatusAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Property, plant and equipment by operating lease status [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromTheRepaymentOfOtherInvestments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds From the Repayment of Other Investments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromTheRepaymentOfOtherInvestments_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Proceeds from the repayment of other investments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProceedsFromTheRepaymentOfOtherInvestments_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Proceeds from the repayment of other investments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FreeSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Free shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FreeSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Free Shares [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FreeSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Free Shares [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfExpectedImpactOfInitialApplicationOfNewStandardsOrInterpretationsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of expected impact of initial application of new standards or interpretations [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfExpectedImpactOfInitialApplicationOfNewStandardsOrInterpretationsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of changes in accounting estimates [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialInstrumentsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information about financial instruments [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfReconciliationOfLiabilitiesArisingFromFinancingActivitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of reconciliation of liabilities arising from financing activities [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfReconciliationOfLiabilitiesArisingFromFinancingActivitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of reconciliation of movements of liabilities to cash flows arising from financing liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfFinancialAssetsMeasuredAtAmortisedCostClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Purchase of financial assets measured at amortised cost, classified as investing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfFinancialAssetsMeasuredAtAmortisedCostClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Acquisition of current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonExecutiveEmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non Executive Employees.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonExecutiveEmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non Executive Employees [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentDerivativeInstrumentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non-current derivative instruments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentDerivativeInstrumentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current derivative instruments [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentDerivativeInstrumentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current Derivative Instruments (EIB warrants) [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current provisions used during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current Provisions Used During the Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentProvisionsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageSharesAndAdjustedWeightedAverageSharesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average ordinary shares used in calculating basic and diluted earnings per share [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageSharesAndAdjustedWeightedAverageSharesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of shares used for computing</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BuildingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Buildings [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BuildingsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Building lease [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DepreciationRightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Depreciation, right-of-use assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DepreciationRightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Depreciation, right-of-use assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DepreciationRightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Depreciation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialLiabilitiesAndLeaseDebtsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of financial liabilities and lease debts.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialLiabilitiesAndLeaseDebtsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of financial liabilities and lease debts explanatory [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialLiabilitiesAndLeaseDebtsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Detail of financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfFinancialLiabilitiesAndLeaseDebtsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughChangesInFairValuesLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through changes in fair values, liabilities arising from financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughChangesInFairValuesLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-cash change in fair value financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassBConvertiblePreferredSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Class B convertible preferred shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassBConvertiblePreferredSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Class B convertible preferred shares [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ClassBConvertiblePreferredSharesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">"Class B" Convertible Preferred Shares [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TrancheBWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Tranche B Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TrancheBWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Tranche B Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DefinedBenefitPlansAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Defined benefit plans [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DefinedBenefitPlansAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Defined benefit plans [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfClassesOfShareCapitalTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of classes of share capital [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfClassesOfShareCapitalTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of classes of share capital [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditReceivableNon-Current_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The portion of the research tax credit receivable which is expected to be refunded within more than twelve months after the reporting period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditReceivableNon-Current_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Research Tax Credit Receivable Non-current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditReceivableNon-Current_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Research tax credit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInForeignExchangeLosses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase Decrease In Foreign Exchange Losses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInForeignExchangeLosses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in foreign exchange losses.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInForeignExchangeLosses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase (decrease) in foreign exchange losses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EffectiveInterestRateOfLoan_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Effective interest rate of loan.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EffectiveInterestRateOfLoan_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Effective Interest Rate of Loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EffectiveInterestRateOfLoan_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Effective interest rate of loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentDerivativeFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current derivative financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentDerivativeFinancialLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current derivative financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Shares issued to the benefit of employees related free share plans</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase In Number Of Ordinary Shares Issued Due To Vesting Of Free Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The increase in the number of ordinary shares issued due to vesting of free shares granted to employees and directors in share-based payment arrangements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughReclassificationBetweenCurrentAndNon-CurrentLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The increase (decrease) in liabilities arising from financing activities resulting from reclassifications between current and non-current activities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughReclassificationBetweenCurrentAndNon-CurrentLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) Through Reclassification Between Current and Non-Current, Liabilities Arising from Financing Activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughReclassificationBetweenCurrentAndNon-CurrentLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Reclassifications financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInPurchasesExternalExpensesAndOther_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Purchases, External Expenses and Other</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInPurchasesExternalExpensesAndOther_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in purchases, external expenses and other.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInPurchasesExternalExpensesAndOther_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in purchases and external expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentAccruedLiabilitiesForPersonnelRelatedExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Current accrued liabilities for personnel related expenses.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentAccruedLiabilitiesForPersonnelRelatedExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current accrued liabilities for personnel related expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CurrentAccruedLiabilitiesForPersonnelRelatedExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accruals for personnel related expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeAndOtherPayablesToTradeSuppliers_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Trade payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeAndOtherPayablesToTradeSuppliers_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeAndOtherPayablesToTradeSuppliers_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Trade payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EquityAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Shareholders' equity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionUsedIncludingProvisionForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provision used including provision for employee benefits.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionUsedIncludingProvisionForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provision Used Including Provision for Employee Benefits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionUsedIncludingProvisionForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BorrowingsByNameAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Borrowings by name [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ConstructionInProgressMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Construction in progress [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ConstructionInProgressMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Assets Under Construction [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughOtherNon-CashMovementsLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The increase (decrease) in liabilities arising from financing activities resulting from other non-cash changes.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughOtherNon-CashMovementsLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) Through Other Non-Cash Movements, Liabilities Arising from Financing Activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseThroughOtherNon-CashMovementsLiabilitiesArisingFromFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other non-cash movements financial liabilities and lease debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialLiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of financial liabilities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityPlusFivePercentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expected volatility plus five percent.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityPlusFivePercentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected Volatility Plus Five Percent [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedVolatilityPlusFivePercentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected volatility +5% [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RevenueThatWasIncludedInContractLiabilityBalanceAtBeginningOfPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue that was included in contract liability balance at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RevenueThatWasIncludedInContractLiabilityBalanceAtBeginningOfPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Revenue that was included in contract liability balance at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfCommitmentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of commitments [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfCommitmentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfCommitmentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Off-balance sheet commitments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Assets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Assets_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Assets at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Assets_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Assets at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Assets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">TOTAL ASSETS</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrepaidExpensesAndOtherCurrentAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Prepaid Expenses and Other Current Assets [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrepaidExpensesAndOtherCurrentAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Prepaid Expenses and Other Current Assets [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PrepaidExpensesAndOtherCurrentAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Prepaid Expenses and Other Current Assets [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReversalOfNonCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Reversal of non current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReversalOfNonCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Reversal Of Non Current Provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ReversalOfNonCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashAndCashEquivalentsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash and cash equivalents [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RiskFreeInterestRateWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The implied yield currently available on zero-coupon government issues of the country in whose currency the exercise price for share options granted is expressed.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RiskFreeInterestRateWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Risk Free Interest Rate Warrants</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RiskFreeInterestRateWarrants_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Risk free rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutOtherCurrentLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of detailed information about other current liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutOtherCurrentLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information about other current liabilities [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutOtherCurrentLiabilitiesExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Other Current Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfAccountingPolicyForGoingConcernExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Description of accounting policy for going concern explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfAccountingPolicyForGoingConcernExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description Of Accounting Policy For Going Concern Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfAccountingPolicyForGoingConcernExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Going concern</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOtherEquityInstrumentsOutstandingInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of other equity instruments outstanding in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOtherEquityInstrumentsOutstandingInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Option outstanding, ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NumberOfOtherEquityInstrumentsOutstandingInSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Option outstanding, beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_UnusedProvisionsReversedIncludingEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Unused provisions reversed including employee benefits.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_UnusedProvisionsReversedIncludingEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Unused Provisions Reversed Including Employee Benefits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_UnusedProvisionsReversedIncludingEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Pension, Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInTradeAccountPayableAndOtherCurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Adjustments for increase (decrease) in trade account payable and other current liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInTradeAccountPayableAndOtherCurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments For Increase (Decrease) In Trade Account Payable And other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForIncreaseDecreaseInTradeAccountPayableAndOtherCurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease in trade payables and other current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ChangeInProvisionsThroughOtherComprehensiveIncomeIncludingProvisionsForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Change in provisions through other comprehensive income including provisions for employee benefits.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ChangeInProvisionsThroughOtherComprehensiveIncomeIncludingProvisionsForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Change in Provisions through Other Comprehensive Income Including Provisions for Employee Benefits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ChangeInProvisionsThroughOtherComprehensiveIncomeIncludingProvisionsForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfOtherProvisionsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of other provisions [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ComponentsOfEquityDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Components of equity [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TypesOfSharebasedPaymentArrangementsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of share-based payment arrangements [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TypesOfSharebasedPaymentArrangementsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Types of share-based payment arrangements [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Weighted-AverageExercisePriceOfAdditionalExercisableOptionsDueToChangeInConversionRatiosShare-BasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The weighted-average exercise price of exercisable options for which the conversion ratios were modified during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Weighted-AverageExercisePriceOfAdditionalExercisableOptionsDueToChangeInConversionRatiosShare-BasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted-average Exercise Price of Additional Exercisable Options Due to Change in Conversion Ratios, Share-based Payment Arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_Weighted-AverageExercisePriceOfAdditionalExercisableOptionsDueToChangeInConversionRatiosShare-BasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted- average exercise price per share, Additional shares due to change in conversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInPrepaidExpensesAndOtherPrepayments_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase Decrease In Prepaid Expenses And Other Prepayments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInPrepaidExpensesAndOtherPrepayments_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase decrease in prepaid expenses and other prepayments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInPrepaidExpensesAndOtherPrepayments_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in prepaid expenses and other prepayments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherSubsidiesReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other subsidies receivables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherSubsidiesReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Subsidies Receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherSubsidiesReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other subsidies</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughNetExchangeDifferencesRightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) through net exchange differences, right-of-use assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IncreaseDecreaseThroughNetExchangeDifferencesRightofuseAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Translation adjustments</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ParValuePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Par value per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ParValuePerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Nominal value</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">European Investment Bank Loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">European Investment Bank Loan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">European Investment Bank Loan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">European Investment Bank Credit Facility [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherOperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other operating income (expense)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherOperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Other operating income and (expense)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherOperatingIncomeExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other operating income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average exercise price of share options outstanding in share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Weighted average exercise price per share, ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Weighted average exercise price per share, beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfCashAndCashEquivalentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of cash and cash equivalents [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfCashAndCashEquivalentsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Details of Cash and Cash Equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MinimumRevenueToBeAchieved_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Minimum revenue to be achieved.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MinimumRevenueToBeAchieved_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Minimum revenue to be achieved</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PreferredSharesConversionRatio_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Preferred shares, conversion ratio.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PreferredSharesConversionRatio_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Preferred Shares Conversion Ratio</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_PreferredSharesConversionRatio_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Conversion ratio</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslationOtherThanTranslationOfForeignOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other comprehensive income, before tax, exchange differences on translation, other than translation of foreign operations</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslationOtherThanTranslationOfForeignOperations_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Currency translation adjustment generated by the parent company</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfQuantitativeInformationAboutRightofuseAssetsTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of quantitative information about right-of-use assets [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustedWeightedAverageShares_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Weighted average number of outstanding shares, net of effects of dilutive potential ordinary shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustedWeightedAverageShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average number of outstanding shares, used to calculate diluted net result per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AdjustedWeightedAverageShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Diluted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of revenue.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Revenue [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Revenue [Table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfIndirectMeasurementOfFairValueOfGoodsOrServicesReceivedShareOptionsGrantedDuringPeriodExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of indirect measurement of fair value of goods or services received, share options granted during period [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfIndirectMeasurementOfFairValueOfGoodsOrServicesReceivedShareOptionsGrantedDuringPeriodExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of assumptions Vesting Details</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AverageLifeOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Average Life Options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AverageLifeOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Average life options.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AverageLifeOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Average life of options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredIncomeOtherThanContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred income other than contract liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredIncomeOtherThanContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other deferred income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current assets [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentAssetsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MilestonePaymentFor10Candidate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Milestone Payment For 10 Candidate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MilestonePaymentFor10Candidate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Milestone payment for 10 candidate.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_MilestonePaymentFor10Candidate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Milestone Payment For 10 Candidate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeAndOtherCurrentPayablesToTradeSuppliers_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Current trade payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_TradeAndOtherCurrentPayablesToTradeSuppliers_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trade payables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinanceIncomeExpenseExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of finance income (cost) [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinanceIncomeExpenseExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Details of Financial Income and Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Commercial litigation other comprehensive income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commercial Litigation Other Comprehensive Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commercial litigation, OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DilutedEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Diluted earnings (loss) per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DilutedEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total diluted earnings (loss) per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DilutedEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Diluted net income (loss) attributable to shareholders of Cellectis, per share ($ /share)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DilutedEarningsLossPerShare_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Diluted net loss per share attributable to shareholders of Cellectis ($ /share)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfReconciliationOfLiabilitiesArisingFromFinancingActivitiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of reconciliation of liabilities arising from financing activities [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CytoviaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Cytovia.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CytoviaMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cytovia [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_FR_lbl" xlink:role="http://www.xbrl.org/2003/role/label">FRANCE</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_FR_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">France [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="country_FR_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">FR</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentVested_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The weighted average fair value at the measurement date of other equity instruments (ie other than share options) vested in a share-based payment arrangement. [Refer: Weighted average [member]".</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentVested_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Fair Value At Measurement Date Other Equity Instrument Vested</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentVested_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average exercise price per share, Vested</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DiscountRate_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Discount rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DiscountRate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Discount rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DiscountRate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Discount rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityRegistrantName_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Entity Registrant Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_EntityRegistrantName_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Registrant Name</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsAdditionsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for termination benefits additions current provisions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsAdditionsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for termination benefits additions current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForTerminationBenefitsAdditionsCurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Current provisions additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentPortionOfNoncurrentLoansReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current portion of non-current loans received</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentPortionOfNoncurrentLoansReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current liability of loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentPortionOfNoncurrentLoansReceived_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Conditional advances</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_StatementOfChangesInEquityTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of changes in equity [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfTradeReceivablesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of trade receivables.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfTradeReceivablesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of trade receivables [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfFinancialAssetsLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of financial assets [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for retirement indemnities reversals.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Retirement Indemnities Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForRetirementIndemnitiesReversals_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Retirement Indemnities , Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in contract liabilities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (Decrease) in Contract Liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in deferred revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInContractLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Decrease in deferred revenue</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="dei_AmendmentDescription_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Amendment Description</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_GauranteedBorrowingAmountPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Gauranteed borrowing amount percentage.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_GauranteedBorrowingAmountPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Gauranteed Borrowing Amount Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_GauranteedBorrowingAmountPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Guaranteed borrowing amount, percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ShorttermDepositsClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Short-term deposits, classified as cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ShorttermDepositsClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash and bank accounts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ShorttermDepositsClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Fixed bank deposits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfAccountingPolicyForTransactionsWithAstraZeneaExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Description of accounting policy for transactions with AstraZenea explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfAccountingPolicyForTransactionsWithAstraZeneaExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Description Of Accounting Policy For Transactions With AstraZenea Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DescriptionOfAccountingPolicyForTransactionsWithAstraZeneaExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accounting treatment of transactions with AstraZeneca</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_StatementOfComprehensiveIncomeAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of comprehensive income [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisposalsAndRetirementsPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disposals and retirements, property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisposalsAndRetirementsPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Disposal</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisposalsAndRetirementsPropertyPlantAndEquipment_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel">Total disposals and retirements, property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DepreciationAndAmortizationExpensesInclusiveRightOfUseAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Depreciation And Amortization Expenses Inclusive Right Of Use Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DepreciationAndAmortizationExpensesInclusiveRightOfUseAmortization_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Depreciation And Amortization Expenses Inclusive Right Of Use Amortization</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DepreciationAndAmortizationExpensesInclusiveRightOfUseAmortization_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Depreciation and amortization expenses (incl. right of use amortization)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ItLicensingAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">It licensing agreements member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ItLicensingAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">It Licensing Agreements [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ItLicensingAgreementsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">IT Licensing Agreements [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SharePremiumMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Share premium [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_SharePremiumMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Premiums Related to Share Capital [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Equity_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Equity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Equity_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Balance at end of year</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Equity_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Equity_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total shareholders' equity</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanTrancheCMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">European Investment Bank Loan Tranche C.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankLoanTrancheCMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">European Investment Bank Loan - Tranche C [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfPropertyPlantAndEquipmentDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of property, plant and equipment [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNon-CurrentFinancialLiabilitiesAndNon-CurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Total Non-Current Financial Liabilities and Non-Current Lease Debts</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TotalNon-CurrentFinancialLiabilitiesAndNon-CurrentLeaseDebtsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Total Non-Current Financial Liabilities and Non-Current Lease Debts [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutNonCurrentFinancialAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of detailed information about non-current financial assets explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutNonCurrentFinancialAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Detailed Information about Non-current Financial Assets Explanatory [Text Block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfDetailedInformationAboutNonCurrentFinancialAssetsExplanatoryTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Summary of Non-current Financial Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfGovernmentGrantsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of government grants [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfGovernmentGrantsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Subsidies Receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentFinancialAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Non-current financial assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentFinancialAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current financial assets [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NonCurrentFinancialAssetsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current Financial Assets [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RemainingContractualLifeOfOption_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Remaining contractual life of option</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RemainingContractualLifeOfOption_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Remaining Contractual Life Of Option</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RemainingContractualLifeOfOption_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Contractual life of options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProceedsFromBorrowingsClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProceedsFromBorrowingsClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Secured Borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProceedsFromBorrowingsClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds from the issuance of share capital and other equity instruments after deduction of transaction costs</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromProductsServices_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of revenue from products and services.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromProductsServices_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Revenue From Products Services</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RevenueFromProductsServices_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Products &amp; services</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MiscellaneousCurrentLiabilitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Miscellaneous current liabilities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseFromSharebasedPaymentTransactionsInWhichGoodsOrServicesReceivedDidNotQualifyForRecognitionAsAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expense from share-based payment transactions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseFromSharebasedPaymentTransactionsInWhichGoodsOrServicesReceivedDidNotQualifyForRecognitionAsAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share-based compensation expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ExpenseFromSharebasedPaymentTransactionsInWhichGoodsOrServicesReceivedDidNotQualifyForRecognitionAsAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total expense from share-based payment transactions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Non current provisions Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Non current provisions beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentProvisions_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total non-current provisions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInFinancialExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Decrease (increase) in financial Expenses.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInFinancialExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase Decrease In Financial Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInFinancialExpenses_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease /increase in financial Expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinanceCost_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other finance cost</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinanceCost_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other financial expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinanceCost_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Other financial expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AccumulatedImpairmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated impairment [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AccumulatedImpairmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Allowance for expected credit losses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfCashGeneratingUnit_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Number of cash generating unit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfCashGeneratingUnit_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Number of cash generating unit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_NumberOfCashGeneratingUnit_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Number of cash generating unit</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinanceIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other financial income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherFinanceIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other finance income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of detailed information about property, plant and equipment [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentTable_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of detailed information about property, plant and equipment [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfPropertyPlantAndEquipmentTable_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Details of Property, Plant and Equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionalProvisionsIncludingProvisionsForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Additional provisions including provisions for employee benefits.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionalProvisionsIncludingProvisionsForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Additional Provisions including Provisions for Employee Benefits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionalProvisionsIncludingProvisionsForEmployeeBenefits_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AccumulatedDepreciationAmortisationAndImpairmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Accumulated depreciation, amortisation and impairment [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AccumulatedDepreciationAmortisationAndImpairmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Accumulated depreciation and impairment [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_AccumulatedDepreciationAmortisationAndImpairmentMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Accumulated Depreciation and Impairment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TechnicalEquipmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Technical equipments.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TechnicalEquipmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Technical Equipments [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TechnicalEquipmentsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Technical Equipment [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpirationPeriodOfStockOptionPlan_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Expiration period of stock option plan.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpirationPeriodOfStockOptionPlan_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expiration Period of Stock Option Plan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpirationPeriodOfStockOptionPlan_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Stock option expire, years</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForDecreaseIncreaseInSubsidiesAndTaxReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Adjustments for decrease (increase) in subsidies and tax receivables to reconcile profit (loss) to net cash flows provided by (used in) operating activities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForDecreaseIncreaseInSubsidiesAndTaxReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Adjustments for Decrease (Increase) in Subsidies and Tax Receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdjustmentsForDecreaseIncreaseInSubsidiesAndTaxReceivables_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in subsidies and tax receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfSensitivityAnalysisOnTheExpectedVolatilityTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of sensitivity analysis on the expected volatility [table text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfSensitivityAnalysisOnTheExpectedVolatilityTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of sensitivity analysis on the expected volatility explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfSensitivityAnalysisOnTheExpectedVolatilityTableTextBlock_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of sensitivity analysis on the expected volatility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of provisions for employee litigation and severance, amounts used during the period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions for employee litigation and severance amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeveranceAmountsUsedDuringThePeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Employee litigation and severance, Amounts used during the period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DateOfGrantOfSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Date of grant of share-based payment arrangement</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DateOfGrantOfSharebasedPaymentArrangement_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Grant date</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Purchase of property, plant and equipment, classified as investing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Acquisition of property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Purchase of property, plant and equipment</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInNon-CurrentRestrictedCash_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Decrease in non-current restricted cash.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInNon-CurrentRestrictedCash_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Decrease in Non-Current Restricted Cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInNon-CurrentRestrictedCash_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease in non-current restricted cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOrRelatedPartyAndMajorShareholdersExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Or Related Party And Major Shareholders Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOrRelatedPartyAndMajorShareholdersExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure or related party and major shareholders explanatory.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOrRelatedPartyAndMajorShareholdersExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Related parties and other major shareholders</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ResearchAndDevelopmentExpense_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Research and development expense</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ResearchAndDevelopmentExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Research and development expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ResearchAndDevelopmentExpense_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel">Total research and development expenses</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Repayments of borrowings, classified as financing activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel">Repayments of borrowings</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Repaid of loan</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Repayments of financial liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedDividendAsPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The percentage of an expected dividend used to calculate the fair value of share options granted.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedDividendAsPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected Dividend As Percentage</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpectedDividendAsPercentage_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected dividends</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non-current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentLiabilities_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total non-current liabilities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_StatementOfCashFlowsAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Statement of cash flows [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FrenchResidentEmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">French Resident Employees.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FrenchResidentEmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">French Resident Employees [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">European investment bank warrants [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">European investment bank warrants [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EuropeanInvestmentBankWarrantsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">European Investment Bank Warrants [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseRemainingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Lease remaining period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseRemainingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Lease Remaining Period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_LeaseRemainingPeriod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Lease remaining period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationsReversal_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of commercial litigations reversal.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationsReversal_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commercial litigations reversal</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationsReversal_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commercial litigation, Reversals</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentRestrictedCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-current restricted cash and cash equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NoncurrentRestrictedCashAndCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Restricted cash</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialTermForSelectionOfCandidateProducts_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Initial term for selection of candidate products.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialTermForSelectionOfCandidateProducts_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Initial Term For Selection Of Candidate Products</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_InitialTermForSelectionOfCandidateProducts_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Initial term for selection of candidate products</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair value of ordinary shares.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value Of Ordinary Shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValueOfOrdinaryShares_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value of ordinary shares</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BorrowingsInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Borrowings, interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BorrowingsInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_BorrowingsInterestRate_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Fixed interest rate</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other provision for charges member.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Provision For Charges [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other provision for charges [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfAssetsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Classes of assets [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ClassesOfAssetsAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Classes of assets [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_NonadjustingEventsAfterReportingPeriodDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Non-adjusting events after reporting period [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsidiesReceivablesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Subsidies receivables current.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsidiesReceivablesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Subsidies receivables current</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_SubsidiesReceivablesCurrent_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total subsidies receivables</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RefundReceivedDueToReversalOfATaxLitigationProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Refund received due to reversal of a tax litigation provision</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_RefundReceivedDueToReversalOfATaxLitigationProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Refund received due to reversal of a tax litigation provision</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EmployeeLitigationAndSeveranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Employee litigation and severance.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EmployeeLitigationAndSeveranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Employee litigation and severance [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_EmployeeLitigationAndSeveranceMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Employee Litigation and Severance [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInOperatingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Cash flows from (used in) operating activities [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CashFlowsFromUsedInOperatingActivitiesAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cash flows from operating activities</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfExpectedVolatilityShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expected volatility, share options granted</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfExpectedVolatilityShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expected volatility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DescriptionOfExpectedVolatilityShareOptionsGranted_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Expected volatility</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Other provision for charges other comprehensive income.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other Provision For Charges Other Comprehensive Income</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_OtherProvisionForChargesOtherComprehensiveIncome_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other provision for charges, OCI</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNonCashGainsRecognizedFromFairValueMeasurements_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase In Non Cash Gains Recognized From Fair Value Measurements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNonCashGainsRecognizedFromFairValueMeasurements_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase in non-cash gains recognized from fair value measurements.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseInNonCashGainsRecognizedFromFairValueMeasurements_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Increase in non-cash gains recognized from fair value measurements</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationsAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount of commercial litigations additions.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationsAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Commercial Litigations Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CommercialLitigationsAdditions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Commercial litigation, Additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Level2OfFairValueHierarchyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Level 2 of fair value hierarchy [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_Level2OfFairValueHierarchyMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Level 2 [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of information about consolidated and non-consolidated structured entities.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure Of Information About Consolidated And Non-consolidated Structured Entities [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of Information about Consolidated and Non-consolidated Structured Entities [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EarningsPerShareExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Earnings per share [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_EarningsPerShareExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Earnings per share</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExecutiveEmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Executive employees.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExecutiveEmployeesMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Executive Employees [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeverance_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Employee litigation and severance, Beginning balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeverance_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Provisions For Employee Litigation and Severance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeverance_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Provisions for employee litigation and severance.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ProvisionsForEmployeeLitigationAndSeverance_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Employee litigation and severance, Ending balance</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherNoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Other non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherNoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Other non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_OtherNoncurrentAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Other non-current assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BPIAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">BPI Agreement [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BPIAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">B P I Agreement [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BPIAgreementMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">B P I Agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInInterestIncomeEarnedOnCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Decrease In Interest Income Earned On Cash Cash Equivalents And Financial Assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInInterestIncomeEarnedOnCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Decrease in interest income earned on cash, cash equivalents and financial assets.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DecreaseInInterestIncomeEarnedOnCashCashEquivalentsAndFinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Decrease in interest income earned on cash, cash equivalents and financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionForNonCurrentProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Addition for non current provision.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionForNonCurrentProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Addition For Non Current Provision</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_AdditionForNonCurrentProvision_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Non current provisions additions</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpenseByNatureLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Line items represent concepts included in a table. These concepts are used to disclose the amount of expenses aggregated according to their nature (for example, depreciation, purchases of materials, transport costs, employee benefits and advertising costs), and not reallocated among functions within the entity.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpenseByNatureLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Expense by Nature [Line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ExpenseByNatureLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Expense by nature [line Items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Collaboration agreement.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_CollaborationAgreementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Collaboration Agreement [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MajorComponentsOfTaxExpenseIncomeAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Major components of tax expense (income) [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredTaxAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Deferred tax assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredTaxAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Deferred tax assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DeferredTaxAssets_lbl" xlink:role="http://www.xbrl.org/2009/role/negatedLabel">Deferred tax assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProceedsFromSalesOfInvestmentsOtherThanInvestmentsAccountedForUsingEquityMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Proceeds from sales of investments other than investments accounted for using equity method</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_ProceedsFromSalesOfInvestmentsOtherThanInvestmentsAccountedForUsingEquityMethod_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Proceeds from the sale of current financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_CategoriesOfFinancialLiabilitiesDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Categories of financial liabilities [domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of revenue [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of revenue [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfRevenueLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Disclosure of revenue [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TypesOfWarrantsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Types of warrants [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_TypesOfWarrantsDomain_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Types of warrants [Domain]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesTable_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of transactions between related parties [table]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">The amount represents the research tax credit income for the period. The research tax credit is a French tax credit calculated based on our claimed amount of eligible research and development expenses in France. It can be offset against French corporate income tax due and the portion in excess (if any) may be refunded at the end of a three fiscal-year period.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Research Tax Credit Amount</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_ResearchTaxCreditAmount_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Research tax credit subsidy</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Weighted average exercise price of share options change in conversion ratios in sharebased payment arrangement 2019.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted Average Exercise Price Of Share Options Change In Conversion Ratios In Sharebased Payment Arrangement 2019</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement2019_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Weighted average exercise price per share, Additional shares due to change in conversion ratios</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValuePerOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Fair value per options.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValuePerOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Fair Value Per Options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValuePerOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Fair value per options (in euros per share)</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_FairValuePerOptions_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Fair value per options</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BankDepositsNotClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Bank deposits, not classified as cash equivalents.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BankDepositsNotClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Bank Deposits Not Classified As Cash Equivalents</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_BankDepositsNotClassifiedAsCashEquivalents_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Bank deposits</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInForeignExchangeGains_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Increase (decrease) in foreign exchange gains.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_IncreaseDecreaseInForeignExchangeGains_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Increase (decrease) in foreign exchange gains</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfImpairmentLossAndReversalOfImpairmentLossLineItems_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of impairment loss and reversal of impairment loss [line items]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_MeasurementAxis_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Measurement [axis]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfActivitiesOfCompanyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">Disclosure of Activities of Company Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfActivitiesOfCompanyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of Activities of Company Explanatory</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_DisclosureOfActivitiesOfCompanyExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">The Company</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel">Financial assets at end of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel">Financial assets at beginning of period</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/totalLabel">Total financial assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_FinancialAssets_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">Book value on the statement of financial position</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfQuantitativeInformationAboutRightofuseAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of quantitative information about right-of-use assets [text block]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfQuantitativeInformationAboutRightofuseAssetsExplanatory_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Right-of-use&#160;assets</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_DisclosureOfClassesOfShareCapitalAbstract_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Disclosure of classes of share capital [abstract]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IssuedCapitalMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Issued capital [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_IssuedCapitalMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Share Capital Issued Capital [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LaterThanOneYearAndNotLaterThanFiveYearsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Later than one year and not later than five years [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_LaterThanOneYearAndNotLaterThanFiveYearsMember_lbl" xlink:role="http://www.xbrl.org/2003/role/terseLabel">One to Five Years [member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StateGuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/documentation">State Guaranteed Loan.</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StateGuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/label">State Guaranteed Loan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="clls_StateGuaranteedLoanMember_lbl" xlink:role="http://www.xbrl.org/2003/role/verboseLabel">State Guaranteed Loan [Member]</link:label>
          <link:label xml:lang="en-US" xlink:type="resource" xlink:label="ifrs-full_WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019_lbl" xlink:role="http://www.xbrl.org/2003/role/label">Weighted average remaining contractual life of outstanding share options</link:label>
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      </link:linkbase>
    </xsd:appinfo>
  </xsd:annotation>
  <xsd:element id="clls_OtherProvisionForChargesUsedDuringThePeriod" name="OtherProvisionForChargesUsedDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProvisionForTaxLitigation" name="ProvisionForTaxLitigation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProvisionForTaxLitigationAdditions" name="ProvisionForTaxLitigationAdditions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationOfShareCapitalExplanatoryTextBlock" name="DisclosureOfDetailedInformationOfShareCapitalExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_PersonnelExpensesMember" name="PersonnelExpensesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ExecutiveOfficersMember" name="ExecutiveOfficersMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenuesAndContractLiabilities" name="AdjustmentsForIncreaseDecreaseInDeferredRevenuesAndContractLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_JointResearchAndCollaborationAgreementInitialInvestmentAgreementSubsequentInvestmentAgreementMember" name="JointResearchAndCollaborationAgreementInitialInvestmentAgreementSubsequentInvestmentAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_TotalNon-CurrentFinancialLiabilitiesAndNon-CurrentLeaseDebtsMember" name="TotalNon-CurrentFinancialLiabilitiesAndNon-CurrentLeaseDebtsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FinancialInstitutionDomain" name="FinancialInstitutionDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_NumberOfShareOptionsExercisableChangeInConversionRatiosInSharebasedPaymentArrangement" name="NumberOfShareOptionsExercisableChangeInConversionRatiosInSharebasedPaymentArrangement" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ValuationMethod" name="ValuationMethod" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_PrimeraTherapeuticsIncMember" name="PrimeraTherapeuticsIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationAboutNonCurrentFinancialAssetsExplanatoryTextBlock" name="DisclosureOfDetailedInformationAboutNonCurrentFinancialAssetsExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AdjustmentsForRealizedForeignExchangeLossesGains" name="AdjustmentsForRealizedForeignExchangeLossesGains" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationAboutProvisionsExplanatory" name="DisclosureOfDetailedInformationAboutProvisionsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ExpectedVolatility" name="ExpectedVolatility" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_ClassBConvertiblePreferredSharesMember" name="ClassBConvertiblePreferredSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_EmployeesMember" name="EmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CellectisMember" name="CellectisMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CarryingAmountAccumulatedDepreciationAmortisationAndImpairmentAndGrossCarryingAmountDomain" name="CarryingAmountAccumulatedDepreciationAmortisationAndImpairmentAndGrossCarryingAmountDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ResearchTaxCreditFinancingsMember" name="ResearchTaxCreditFinancingsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_StockOption1Member" name="StockOption1Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_InvesteeDomain" name="InvesteeDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ClassesOfCommitmentsAxis" name="ClassesOfCommitmentsAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AmountToBeRepaid" name="AmountToBeRepaid" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShare-BasedPaymentArrangement" name="NumberOfAdditionalSharesDueToChangeInConversationRatioShare-BasedPaymentArrangement" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_InitialFairValueAmount" name="InitialFairValueAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_NumberOfExercisableShareOptionsForfeitedInShareBasedPaymentArrangement" name="NumberOfExercisableShareOptionsForfeitedInShareBasedPaymentArrangement" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AstraZenecaIrelandMember" name="AstraZenecaIrelandMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_NonCurrentFinancialLiabilitiesMember" name="NonCurrentFinancialLiabilitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_RestrictedStockUnitMember" name="RestrictedStockUnitMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DeferredRevenues" name="DeferredRevenues" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ExpenseByNatureLineItems" name="ExpenseByNatureLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_NonCurrentLeaseDebtsMember" name="NonCurrentLeaseDebtsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_TypesOfWarrantsAxis" name="TypesOfWarrantsAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_StateGuaranteedLoanMember" name="StateGuaranteedLoanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_VestingPeriodShare-BasedPaymentArrangements" name="VestingPeriodShare-BasedPaymentArrangements" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_TotalUpfrontPayments" name="TotalUpfrontPayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_AccruedAndUnpaidInterestAccruedMember" name="AccruedAndUnpaidInterestAccruedMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_EffectiveInterestRateOfLoan" name="EffectiveInterestRateOfLoan" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_VestingOfFreeSharesAndStockOptionExercisesValue" name="VestingOfFreeSharesAndStockOptionExercisesValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_CurrentFinancialAssetsAndCashAndCashEquivalents" name="CurrentFinancialAssetsAndCashAndCashEquivalents" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_RiskFreeInterestRate" name="RiskFreeInterestRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_WeightedAverageExercisePriceOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements" name="WeightedAverageExercisePriceOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseDecreaseRevenues" name="IncreaseDecreaseRevenues" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_FinancialLiabilityMaturity" name="FinancialLiabilityMaturity" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ProvisionsForEmployeeLitigationAndServerance" name="ProvisionsForEmployeeLitigationAndServerance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_RetirementIndemnitiesMember" name="RetirementIndemnitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_EuropeanInvestmentBankWarrantsMember" name="EuropeanInvestmentBankWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_WarrantsValuationAbstract" name="WarrantsValuationAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ReversalOfCurrentProvisions" name="ReversalOfCurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DepreciationAndAmortizationExpensesInclusiveRightOfUseAmortization" name="DepreciationAndAmortizationExpensesInclusiveRightOfUseAmortization" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsAbstract" name="DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_GrantAndRefundableAdvanceAgreementMember" name="GrantAndRefundableAdvanceAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AverageLifeOptions" name="AverageLifeOptions" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationAboutFairValueSharePriceTextBlock" name="DisclosureOfDetailedInformationAboutFairValueSharePriceTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsOutstanding" name="WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsOutstanding" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_OfficeAndLaboratoryEquipmentMember" name="OfficeAndLaboratoryEquipmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesTable" name="DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseInNonCashGainsRecognizedFromFairValueMeasurements" name="IncreaseInNonCashGainsRecognizedFromFairValueMeasurements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncreaseDecreaseInPrepaidExpensesAndOtherPrepayments" name="IncreaseDecreaseInPrepaidExpensesAndOtherPrepayments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_NumberOfExercisableShareOptionsExercisedInShareBasedPaymentArrangement" name="NumberOfExercisableShareOptionsExercisedInShareBasedPaymentArrangement" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AgreementOneAxis" name="AgreementOneAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionUsedIncludingProvisionForEmployeeBenefits" name="ProvisionUsedIncludingProvisionForEmployeeBenefits" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_TotalCurrentFinancialLiabilitiesAndLeaseDebts" name="TotalCurrentFinancialLiabilitiesAndLeaseDebts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ReversalOfNonCurrentProvisions" name="ReversalOfNonCurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_CurrentProvisionsUsedDuringThePeriod" name="CurrentProvisionsUsedDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NonCurrentProvisionsUsedDuringThePeriod" name="NonCurrentProvisionsUsedDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock" name="DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_PrepaidExpensesAndOtherCurrentAssetsLineItems" name="PrepaidExpensesAndOtherCurrentAssetsLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForEmployeeLitigationAndSeveranceAdditions" name="ProvisionsForEmployeeLitigationAndSeveranceAdditions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_AgreementTwoDomain" name="AgreementTwoDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_InitialInvestmentAgreementMember" name="InitialInvestmentAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_InterestIncomeOnCashCashEquivalentsAndFinancialAssets" name="InterestIncomeOnCashCashEquivalentsAndFinancialAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_OtherProvisionForCharges" name="OtherProvisionForCharges" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_GauranteedBorrowingAmountPercentage" name="GauranteedBorrowingAmountPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_NumberOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement" name="NumberOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseInFinancialIncome" name="IncreaseInFinancialIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_LeaseRemainingPeriod" name="LeaseRemainingPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_BankDepositsNotClassifiedAsCashEquivalents" name="BankDepositsNotClassifiedAsCashEquivalents" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationAboutDeferredIncomeAndContractLiabilitiesExplanatory" name="DisclosureOfDetailedInformationAboutDeferredIncomeAndContractLiabilitiesExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_LeasePotentialObligations" name="LeasePotentialObligations" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_LicenseAndCollaborationAgreementsMember" name="LicenseAndCollaborationAgreementsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_LeaseRemainingTerm" name="LeaseRemainingTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_JointCollaborationAndResearchAgreementMember" name="JointCollaborationAndResearchAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForEmployeeLitigationAndSeveranceOtherComprehensiveIncome" name="ProvisionsForEmployeeLitigationAndSeveranceOtherComprehensiveIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_AccrualsAndDeferredIncomeIncludingContractLiabilitiesTable" name="AccrualsAndDeferredIncomeIncludingContractLiabilitiesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_TotalCurrentFinancialLiabilitiesAndCurrentLeaseDebtsMember" name="TotalCurrentFinancialLiabilitiesAndCurrentLeaseDebtsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeCurrentProvisions" name="ProvisionsForTerminationBenefitsOtherComprehensiveIncomeCurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_CollaborationAgreementDomain" name="CollaborationAgreementDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OtherProvisionForChargesMember" name="OtherProvisionForChargesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseDecreaseInOtherIncome" name="IncreaseDecreaseInOtherIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsDuringThePeriodCurrentProvisions" name="ProvisionsForTerminationBenefitsDuringThePeriodCurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NonCurrentFinancialAssetsMember" name="NonCurrentFinancialAssetsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ContractualLifeOptions" name="ContractualLifeOptions" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_WarrantExercisePrice" name="WarrantExercisePrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfDetailedFinancialLiabilitiesAndLeaseDebtsExplanatory" name="DisclosureOfDetailedFinancialLiabilitiesAndLeaseDebtsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ProvisionForTaxLitigationOtherComprehensiveIncome" name="ProvisionForTaxLitigationOtherComprehensiveIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncreaseDueToConsiderationReceivedFromCustomersContractLiabilities" name="IncreaseDueToConsiderationReceivedFromCustomersContractLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_TotalFairValue" name="TotalFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_AstraZenecaMember" name="AstraZenecaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ConsolidatedOperationsAbstract" name="ConsolidatedOperationsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_UnusedProvisionsReversedIncludingEmployeeBenefits" name="UnusedProvisionsReversedIncludingEmployeeBenefits" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DeferredRevenueIncludingUpfrontPayment" name="DeferredRevenueIncludingUpfrontPayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_CommercialLitigationMember" name="CommercialLitigationMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ChangeInProvisionsThroughOtherComprehensiveIncomeIncludingProvisionsForEmployeeBenefits" name="ChangeInProvisionsThroughOtherComprehensiveIncomeIncludingProvisionsForEmployeeBenefits" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfFinancialAssetsAndLiabilitiesTable" name="DisclosureOfFinancialAssetsAndLiabilitiesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentVested" name="WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentVested" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_FrenchResidentEmployeesMember" name="FrenchResidentEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DescriptionOfPresentationCurrencyExplanatory" name="DescriptionOfPresentationCurrencyExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfActivitiesOfCompanyExplanatory" name="DisclosureOfActivitiesOfCompanyExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeSharesAndStockOptionExercises" name="IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeSharesAndStockOptionExercises" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_PreferredSharesConversionRatio" name="PreferredSharesConversionRatio" type="xbrli:pureItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_RevenueFromProductsServices" name="RevenueFromProductsServices" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement" name="WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AgreementOneDomain" name="AgreementOneDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfMaturitiesOfFinancialLiabilitiesExplanatoryTextBlock" name="DisclosureOfMaturitiesOfFinancialLiabilitiesExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DiscountRate" name="DiscountRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AdjustmentsForIncreaseDecreaseInDeferredRevenueAndContractLiabilities" name="AdjustmentsForIncreaseDecreaseInDeferredRevenueAndContractLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ProvisionsForEmployeeLitigationAndSeveranceReversal" name="ProvisionsForEmployeeLitigationAndSeveranceReversal" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_BPIAgreementMember" name="BPIAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ClassAConvertiblePreferredSharesMember" name="ClassAConvertiblePreferredSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_VotingAgreementWithCibusMember" name="VotingAgreementWithCibusMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FixedInterestRate" name="FixedInterestRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_ITLicensingAgreementMember" name="ITLicensingAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseDecreaseThroughReclassificationBetweenCurrentAndNon-CurrentLiabilitiesArisingFromFinancingActivities" name="IncreaseDecreaseThroughReclassificationBetweenCurrentAndNon-CurrentLiabilitiesArisingFromFinancingActivities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_CellectisIncMember" name="CellectisIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_SharePriceOfWarrant" name="SharePriceOfWarrant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AllocationOfPriorPeriodGainLoss" name="AllocationOfPriorPeriodGainLoss" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NonCurrentDerivativeInstrumentsMember" name="NonCurrentDerivativeInstrumentsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseDecreaseInForeignExchangeGains" name="IncreaseDecreaseInForeignExchangeGains" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_MinimumRevenueToBeAchieved" name="MinimumRevenueToBeAchieved" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProvisionForTaxLitigationUsedDuringThePeriod" name="ProvisionForTaxLitigationUsedDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_PrepaidExpensesAndOtherCurrentAssetsTable" name="PrepaidExpensesAndOtherCurrentAssetsTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CashAndCashEquivalentMember" name="CashAndCashEquivalentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FairValuePerOptions" name="FairValuePerOptions" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_SocialSecurityContributionsOnStockOptionGrants" name="SocialSecurityContributionsOnStockOptionGrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_CommercialLitigationOtherComprehensiveIncome" name="CommercialLitigationOtherComprehensiveIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DescriptionOfExpectedTermOfShareOptionsGranted" name="DescriptionOfExpectedTermOfShareOptionsGranted" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseInResearchAndDevelopmentExpense" name="IncreaseInResearchAndDevelopmentExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DescriptionOfAccountingPolicyForTransactionsWithAstraZeneaExplanatory" name="DescriptionOfAccountingPolicyForTransactionsWithAstraZeneaExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_SubsidiesReceivablesCurrent" name="SubsidiesReceivablesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ProceedsFromSaleOfPreferredShares" name="ProceedsFromSaleOfPreferredShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_AgreementAxis" name="AgreementAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CurrentFinancialLiabilitiesMember" name="CurrentFinancialLiabilitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfDeferredIncomeAndContractLiabilitiesExplanatory" name="DisclosureOfDeferredIncomeAndContractLiabilitiesExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement2019" name="WeightedAverageExercisePriceOfShareOptionsChangeInConversionRatiosInSharebasedPaymentArrangement2019" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_NumberOfWarrantsIssued" name="NumberOfWarrantsIssued" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentGranted" name="WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentGranted" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationOfReconciliationOfChangesInRightOfUseAssetsExplanatory" name="DisclosureOfDetailedInformationOfReconciliationOfChangesInRightOfUseAssetsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfOtherReceivablesPrepaymentsAndOtherCurrentAssetsAbstract" name="DisclosureOfOtherReceivablesPrepaymentsAndOtherCurrentAssetsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OperatingExpenseAbstract" name="OperatingExpenseAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_NumberOfCashGeneratingUnit" name="NumberOfCashGeneratingUnit" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CytoviaMember" name="CytoviaMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FairValueOfExpectedVolatilityAmountLessFivePercentage" name="FairValueOfExpectedVolatilityAmountLessFivePercentage" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_IncreaseDecreaseInTradeReceivables" name="IncreaseDecreaseInTradeReceivables" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProvisionForTaxLitigationMember" name="ProvisionForTaxLitigationMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ConsolidatedOperationsLineItems" name="ConsolidatedOperationsLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfInformationConcerningGroupsConsolidatedOperartionsExplanatory" name="DisclosureOfInformationConcerningGroupsConsolidatedOperartionsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DecreaseThroughFinancingCashFlowsInterestPaymentLiabilitiesArisingFromFinancingActivities" name="DecreaseThroughFinancingCashFlowsInterestPaymentLiabilitiesArisingFromFinancingActivities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NonCurrentProvisionsDuringThePeriod" name="NonCurrentProvisionsDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ResearchAndDevelopmentExpensesMember" name="ResearchAndDevelopmentExpensesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_SubsidiesReceivablesMember" name="SubsidiesReceivablesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsTable" name="DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CellectisBiologicsIncMember" name="CellectisBiologicsIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_TradeReceivablesAndOtherCurrentAssetsExplanatory" name="TradeReceivablesAndOtherCurrentAssetsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_TrancheCWarrantsMember" name="TrancheCWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsExplanatoryTextBlock" name="ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_MajorShareholdersDomain" name="MajorShareholdersDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfFinancialLiabilitiesAndLeaseDebtsExplanatoryTextBlock" name="DisclosureOfFinancialLiabilitiesAndLeaseDebtsExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseDecreaseInFinancialExpenses" name="IncreaseDecreaseInFinancialExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesLineItems" name="DisclosureOfInformationAboutConsolidatedAndNonConsolidatedStructuredEntitiesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsTextBlock" name="ScheduleDisclosingInformationRelatedToDetailsOfNon-CurrentFinancialAssetsAndOtherNon-CurrentAssetsTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ResearchTaxCreditReceivableNon-Current" name="ResearchTaxCreditReceivableNon-Current" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_FinancialInstitutionAxis" name="FinancialInstitutionAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_RemeasurementOfTheContractualCashFlowsMember" name="RemeasurementOfTheContractualCashFlowsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DecreaseDueToRevenueRecognitionContractLiabilities" name="DecreaseDueToRevenueRecognitionContractLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioExercisableOptions" name="NumberOfAdditionalSharesDueToChangeInConversationRatioExercisableOptions" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts" name="TotalNonCurrentFinancialLiabilitiesAndNonCurrentLeaseDebts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_PercentageOfChangesInIncomeTaxExpense" name="PercentageOfChangesInIncomeTaxExpense" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_FinanceIncomeExpenseAbstract" name="FinanceIncomeExpenseAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfNumberAndGrantDateFairValueOfOtherEquityInstrumentsExplanatory" name="DisclosureOfNumberAndGrantDateFairValueOfOtherEquityInstrumentsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_LeaseAgreementTerm" name="LeaseAgreementTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_WeightedAverageExercisePriceOfShareOptionsExercisableForfeitedOrExpiredInShareBasedPaymentArrangements" name="WeightedAverageExercisePriceOfShareOptionsExercisableForfeitedOrExpiredInShareBasedPaymentArrangements" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfInterestsInConsolidationAndNonConsolidatedEntitiesTextBlock" name="DisclosureOfInterestsInConsolidationAndNonConsolidatedEntitiesTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfNumberAndWeightedAverageGrantDateFairValueOfOtherEquityInstrumentsExplanatory" name="DisclosureOfNumberAndWeightedAverageGrantDateFairValueOfOtherEquityInstrumentsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_InitialTermForSelectionOfCandidateProducts" name="InitialTermForSelectionOfCandidateProducts" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTaxFromContinuingOperations" name="OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTaxFromContinuingOperations" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ConvertibleNotesMember" name="ConvertibleNotesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_LeaseOptionToExtendLeaseAgreement" name="LeaseOptionToExtendLeaseAgreement" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_OtherOperatingExpenses" name="OtherOperatingExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_FairValueOfWarrants" name="FairValueOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_WeightedAverageExercisePriceOfShareOptionsExercisableExercisedInShareBasedPaymentArrangements" name="WeightedAverageExercisePriceOfShareOptionsExercisableExercisedInShareBasedPaymentArrangements" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CurrentSubsidiesReceivables" name="CurrentSubsidiesReceivables" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DecreaseInFinancialIncome" name="DecreaseInFinancialIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_PrincipalMember" name="PrincipalMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FreeSharesMember" name="FreeSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AgreeementAxis" name="AgreeementAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivables" name="IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivables" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DecreaseInInterestIncomeEarnedOnCashCashEquivalentsAndFinancialAssets" name="DecreaseInInterestIncomeEarnedOnCashCashEquivalentsAndFinancialAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_PurchasesAndExternalExpenses" name="PurchasesAndExternalExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ThresholdPercentageOfOwnershipInOutstandingCommonStockToEnactIndemnificationAgreement" name="ThresholdPercentageOfOwnershipInOutstandingCommonStockToEnactIndemnificationAgreement" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ContractualRepaymentScheduleMember" name="ContractualRepaymentScheduleMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AdditionalProvisionsIncludingProvisionsForEmployeeBenefits" name="AdditionalProvisionsIncludingProvisionsForEmployeeBenefits" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NonExecutiveEmployeesMember" name="NonExecutiveEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_SharePriceWarrants" name="SharePriceWarrants" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfSensitivityAnalysisOnTheExpectedVolatilityTableTextBlock" name="DisclosureOfSensitivityAnalysisOnTheExpectedVolatilityTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AmendmentAgreementOneMember" name="AmendmentAgreementOneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OperatingExpensesAndOtherOperatingIncome" name="OperatingExpensesAndOtherOperatingIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProceedsFromTheRepaymentOfOtherInvestments" name="ProceedsFromTheRepaymentOfOtherInvestments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DisclosureOfBasisOfPreparationOfFinancialStatementsAccountingPolicyInformationExplanatory" name="DisclosureOfBasisOfPreparationOfFinancialStatementsAccountingPolicyInformationExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_TrancheAWarrantsMember" name="TrancheAWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseDecreaseInContractLiabilities" name="IncreaseDecreaseInContractLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsForfeited" name="WeightedAverageFairValueAtMeasurementDateOtherEquityInstrumentsForfeited" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DecreaseInNon-CurrentRestrictedCash" name="DecreaseInNon-CurrentRestrictedCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_NonEmployeeWarrantsMember" name="NonEmployeeWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CommercialLitigationAmountsUsedDuringThePeriod" name="CommercialLitigationAmountsUsedDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_WarrantExpirationDate" name="WarrantExpirationDate" type="xbrli:dateItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_CurrentFinancialAssetsMember" name="CurrentFinancialAssetsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_WeightedAverageExercisePriceOfAdditionalShareDueToChangeInConversionRatiosShareBasedPaymentArrangement" name="WeightedAverageExercisePriceOfAdditionalShareDueToChangeInConversionRatiosShareBasedPaymentArrangement" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CytoviaAgreementMember" name="CytoviaAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AdditionForNonCurrentProvision" name="AdditionForNonCurrentProvision" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_VestingPeriodForShareBasedPaymentArrangements" name="VestingPeriodForShareBasedPaymentArrangements" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfInformationAboutShareBasedPaymentAwardStockOptionsValuationAssumptionsExplanatory" name="DisclosureOfInformationAboutShareBasedPaymentAwardStockOptionsValuationAssumptionsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_NumberOfWarrantGranted" name="NumberOfWarrantGranted" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_NumberOfAdditionalSharesDueToChangeInConversationRatioShareBasedPaymentArrangement" name="NumberOfAdditionalSharesDueToChangeInConversationRatioShareBasedPaymentArrangement" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AgreementDomain" name="AgreementDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CurrentProvisionsOtherComprehensiveIncome" name="CurrentProvisionsOtherComprehensiveIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncreaseInDepreciationAndAmortizationExpenses" name="IncreaseInDepreciationAndAmortizationExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationAboutCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock" name="DisclosureOfDetailedInformationAboutCurrentFinancialAssetsAndCashAndCashEquivalentsExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_TaxAndSocialReceivablesCurrent" name="TaxAndSocialReceivablesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_CurrentPortionOfState-GuaranteedLoanMember" name="CurrentPortionOfState-GuaranteedLoanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_Non-CurrentPortionOfState-GuaranteedLoanMember" name="Non-CurrentPortionOfState-GuaranteedLoanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CurrentLeaseDebtsMember" name="CurrentLeaseDebtsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ExpectedAmountOfDiscountingAdjustment" name="ExpectedAmountOfDiscountingAdjustment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ReallocatedProceedsFromSaleOfOrdinaryShares" name="ReallocatedProceedsFromSaleOfOrdinaryShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ExpectedVolatilityWarrants" name="ExpectedVolatilityWarrants" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_ExecutiveEmployeesMember" name="ExecutiveEmployeesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_RiskFreeInterestRateWarrants" name="RiskFreeInterestRateWarrants" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseInSellingGeneralAndAdministrativeExpenses" name="IncreaseInSellingGeneralAndAdministrativeExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ProceedsFromSaleOfOrdinaryShares" name="ProceedsFromSaleOfOrdinaryShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_IncreaseDecreaseThroughOtherNon-CashMovementsLiabilitiesArisingFromFinancingActivities" name="IncreaseDecreaseThroughOtherNon-CashMovementsLiabilitiesArisingFromFinancingActivities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_FairValueOfExpectedVolatilityAmount" name="FairValueOfExpectedVolatilityAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_IncreaseInPersonnelExpenses" name="IncreaseInPersonnelExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_TermsOfRepayment" name="TermsOfRepayment" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CommercialLitigations" name="CommercialLitigations" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfScopeOfConsolidationAndNonConsolidatedEntitiesAbstract" name="DisclosureOfScopeOfConsolidationAndNonConsolidatedEntitiesAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForRetirementIndemnitiesReversals" name="ProvisionsForRetirementIndemnitiesReversals" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_AggregateCreditFacility" name="AggregateCreditFacility" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfScheduleOfOffBalanceSheetCommitmentsExplanatory" name="DisclosureOfScheduleOfOffBalanceSheetCommitmentsExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfNumberOfOutstandingOptionWeightedAverageExercisePriceAndWeightedAverageRemainingContractualLifeExplanatory" name="DisclosureOfNumberOfOutstandingOptionWeightedAverageExercisePriceAndWeightedAverageRemainingContractualLifeExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DescriptionOfInputsUsedInFairValueMeasurementLiabilitiesTableTextBlock" name="DescriptionOfInputsUsedInFairValueMeasurementLiabilitiesTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DerivativesByNameDomain" name="DerivativesByNameDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OtherCurrentLiabilities1Member" name="OtherCurrentLiabilities1Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsAdditionsCurrentProvisions" name="ProvisionsForTerminationBenefitsAdditionsCurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_RemainingContractualLifeOfOption" name="RemainingContractualLifeOfOption" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsReversalsCurrentProvisions" name="ProvisionsForTerminationBenefitsReversalsCurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_SharesEntitlementPerOption" name="SharesEntitlementPerOption" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_TradePayablesMember" name="TradePayablesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ShareIssuancePrice" name="ShareIssuancePrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_ResearchTaxCreditFinancingMember" name="ResearchTaxCreditFinancingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ConsolidatedOperationsTable" name="ConsolidatedOperationsTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ClinicalAndRdAgreementsMember" name="ClinicalAndRdAgreementsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AgreementTwoAxis" name="AgreementTwoAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProceedsFromIssuingSharesAndOtherEquityInstrumentsNetOfTransactionCosts" name="ProceedsFromIssuingSharesAndOtherEquityInstrumentsNetOfTransactionCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_TechnicalEquipmentsMember" name="TechnicalEquipmentsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AmendedAndRestatedAgreementMember" name="AmendedAndRestatedAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForEmployeeLitigationAndSeverance" name="ProvisionsForEmployeeLitigationAndSeverance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_TextBlock1Abstract" name="TextBlock1Abstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_SalesOfNon-CurrentFinancialAssetsClassifiedAsInvestingActivities" name="SalesOfNon-CurrentFinancialAssetsClassifiedAsInvestingActivities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_AdjustmentForDecreaseIncreaseInTradeReceivablesAndOtherCurrentAssets" name="AdjustmentForDecreaseIncreaseInTradeReceivablesAndOtherCurrentAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_BpifranceMember" name="BpifranceMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsCurrentProvisions" name="ProvisionsForTerminationBenefitsCurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_TransactionCosts" name="TransactionCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_Non-CurrentLeaseLiabilitiesMember" name="Non-CurrentLeaseLiabilitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncomeTaxReceivableCurrent" name="IncomeTaxReceivableCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_LeasedPremisesMember" name="LeasedPremisesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_InvesteeAxis" name="InvesteeAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_VariableConsiderationAmount" name="VariableConsiderationAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_OtherOperatingIncome1" name="OtherOperatingIncome1" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ExpenseByNatureTable" name="ExpenseByNatureTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OptionLifeShareOptionGranted" name="OptionLifeShareOptionGranted" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_OtherProvisionForChargesDuringThePeriod" name="OtherProvisionForChargesDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_AccrualsAndDeferredIncomeIncludingContractLiabilitiesLineItems" name="AccrualsAndDeferredIncomeIncludingContractLiabilitiesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsTable" name="DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CollaborationAgreementPaymentReallocated" name="CollaborationAgreementPaymentReallocated" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncreaseThroughCapitalizationOfInterestExpenseNon-CashLiabilitiesArisingFromFinancingActivities" name="IncreaseThroughCapitalizationOfInterestExpenseNon-CashLiabilitiesArisingFromFinancingActivities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_AdjustmentsForIncreaseDecreaseInTradeAccountPayableAndOtherCurrentLiabilities" name="AdjustmentsForIncreaseDecreaseInTradeAccountPayableAndOtherCurrentLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ProvisionsForRetirementIndemnities" name="ProvisionsForRetirementIndemnities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_CalyxtMember" name="CalyxtMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_NumberOfSharesEntitledPerOption" name="NumberOfSharesEntitledPerOption" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ProvisionsForRetirementIndemnitiesAdditions" name="ProvisionsForRetirementIndemnitiesAdditions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_TrancheBWarrantsMember" name="TrancheBWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CollaborationAgreementUpfrontPaymentReceived" name="CollaborationAgreementUpfrontPaymentReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_DisclosureOrRelatedPartyAndMajorShareholdersExplanatory" name="DisclosureOrRelatedPartyAndMajorShareholdersExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_AdjustmentsForDecreaseIncreaseInSubsidiesAndTaxReceivables" name="AdjustmentsForDecreaseIncreaseInSubsidiesAndTaxReceivables" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_NumberOfDerivativeInstrumentsWarrantGranted" name="NumberOfDerivativeInstrumentsWarrantGranted" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsLineItems" name="DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsAndAwardsLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsLineItems" name="DisclosureOfCurrentFinancialAssetsAndCashAndCashEquivalentsLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ExpirationPeriodOfStockOptionPlan" name="ExpirationPeriodOfStockOptionPlan" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_EuropeanInvestmentBankLoanTrancheBMember" name="EuropeanInvestmentBankLoanTrancheBMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FinancialLiabilitiesAndLeaseDebts" name="FinancialLiabilitiesAndLeaseDebts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProvisionsForRetirementIndemnitiesOtherComprehensiveIncome" name="ProvisionsForRetirementIndemnitiesOtherComprehensiveIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_EmployeeLitigationAndSeveranceMember" name="EmployeeLitigationAndSeveranceMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ExpectedDividendAsPercentage" name="ExpectedDividendAsPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_BPIRefundableAdvanceAgreementMember" name="BPIRefundableAdvanceAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseDecreaseInInterestIncomeFromCashCashEquivalentsAndFinancialAssets" name="IncreaseDecreaseInInterestIncomeFromCashCashEquivalentsAndFinancialAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ResearchTaxCreditAmount" name="ResearchTaxCreditAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivablesDueToForeignExchangeImpact" name="IncreaseDecreaseInNon-CurrentResearchTaxCreditReceivablesDueToForeignExchangeImpact" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_EuropeanInvestmentBankLoanTrancheCMember" name="EuropeanInvestmentBankLoanTrancheCMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_Weighted-AverageExercisePriceOfAdditionalExercisableOptionsDueToChangeInConversionRatiosShare-BasedPaymentArrangement" name="Weighted-AverageExercisePriceOfAdditionalExercisableOptionsDueToChangeInConversionRatiosShare-BasedPaymentArrangement" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CibusIncMember" name="CibusIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfInformationAboutAssumptionsUsedAndValuationResultsTextBlock" name="DisclosureOfInformationAboutAssumptionsUsedAndValuationResultsTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ExpirationDate" name="ExpirationDate" type="xbrli:dateItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ItLicensingAgreementsMember" name="ItLicensingAgreementsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ExecutiveOfficersAndChairmanOfBoardOfDirectorsMember" name="ExecutiveOfficersAndChairmanOfBoardOfDirectorsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfTradeReceivablesLineItems" name="DisclosureOfTradeReceivablesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_SellingGeneralAndAdministrativeExpenses1Member" name="SellingGeneralAndAdministrativeExpenses1Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfRevenueTable" name="DisclosureOfRevenueTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CommercialLitigationsReversal" name="CommercialLitigationsReversal" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ExpectedVolatilityLessFivePercentMember" name="ExpectedVolatilityLessFivePercentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_PercentageOfDebtRepaymentTerms" name="PercentageOfDebtRepaymentTerms" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_OptionVestingPeriod" name="OptionVestingPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsReversalsNoncurrentProvisions" name="ProvisionsForTerminationBenefitsReversalsNoncurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ReserachTaxCreditReceivableCurrent" name="ReserachTaxCreditReceivableCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_ScheduleOfBreakdownOfRightOfUseAssetsAbstract" name="ScheduleOfBreakdownOfRightOfUseAssetsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionForTaxLitigationDuringThePeriod" name="ProvisionForTaxLitigationDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ScheduleOfOutstandingBalancesWithRelatedPartiesExplanatoryTableTextBlock" name="ScheduleOfOutstandingBalancesWithRelatedPartiesExplanatoryTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ExpectedDividendsWarrants" name="ExpectedDividendsWarrants" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_ScheduleOfOutstandingBalancesWithOtherMajorShareholdersExplanatoryTableTextBlock" name="ScheduleOfOutstandingBalancesWithOtherMajorShareholdersExplanatoryTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsOtherComprehensiveIncomeNoncurrentProvisions" name="ProvisionsForTerminationBenefitsOtherComprehensiveIncomeNoncurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_SAFreeSharesMember" name="SAFreeSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_Receivables1Abstract" name="Receivables1Abstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsAdditionsNoncurrentProvisions" name="ProvisionsForTerminationBenefitsAdditionsNoncurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_EuropeanInvestmentBankLoanMember" name="EuropeanInvestmentBankLoanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_SubsequentInvestmentAgreementMember" name="SubsequentInvestmentAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsDuringThePeriodNoncurrentProvisions" name="ProvisionsForTerminationBenefitsDuringThePeriodNoncurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ProvisionForTaxLitigationReversals" name="ProvisionForTaxLitigationReversals" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_TypesOfWarrantsDomain" name="TypesOfWarrantsDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_PercentageOfFairMarketValue" name="PercentageOfFairMarketValue" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseDecreaseThroughChangesInForeignExchangeRatesContractLiabilities" name="IncreaseDecreaseThroughChangesInForeignExchangeRatesContractLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_OtherSubsidiesReceivables" name="OtherSubsidiesReceivables" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_InitialFairValueOfLoan" name="InitialFairValueOfLoan" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_FairValueOfOrdinaryShares" name="FairValueOfOrdinaryShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_WarrantsValuationMethod" name="WarrantsValuationMethod" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DeferredExpensesAndOtherCurrentAssets" name="DeferredExpensesAndOtherCurrentAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_AverageLifeOfOptions" name="AverageLifeOfOptions" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CurrentProvisionsDuringThePeriod" name="CurrentProvisionsDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_PropertyPlantAndEquipmentAccumulatedDepreciationAmortisationAndImpairment" name="PropertyPlantAndEquipmentAccumulatedDepreciationAmortisationAndImpairment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_ExpectedVolatilityPlusFivePercentMember" name="ExpectedVolatilityPlusFivePercentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ClassOfWarrantsOrRightDomain" name="ClassOfWarrantsOrRightDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OtherProvisionForChargesReversals" name="OtherProvisionForChargesReversals" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_RefundReceivedDueToReversalOfATaxLitigationProvision" name="RefundReceivedDueToReversalOfATaxLitigationProvision" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfTradeReceivablesTable" name="DisclosureOfTradeReceivablesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OtherCurrentFinancialLiabilitiesMember" name="OtherCurrentFinancialLiabilitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForRetirementIndemnitiesAmountsUsedDuringThePeriod" name="ProvisionsForRetirementIndemnitiesAmountsUsedDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_LeasedEquipmentMember" name="LeasedEquipmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CurrentLeaseLiabilitiesMember" name="CurrentLeaseLiabilitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfRevenueAndOtherIncomeExplanatoryTableTextBlock" name="DisclosureOfRevenueAndOtherIncomeExplanatoryTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DerivativesByNameAxis" name="DerivativesByNameAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ConditionalAdvancesMember" name="ConditionalAdvancesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DisclosureOfNonCurrentFinancialAssetsExplanatoryTextBlock" name="DisclosureOfNonCurrentFinancialAssetsExplanatoryTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_UnderlyingStockPriceAtGrantDate" name="UnderlyingStockPriceAtGrantDate" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CurrentAccruedLiabilitiesForPersonnelRelatedExpenses" name="CurrentAccruedLiabilitiesForPersonnelRelatedExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncreaseDecreaseInPurchasesExternalExpensesAndOther" name="IncreaseDecreaseInPurchasesExternalExpensesAndOther" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_NumberOfOperatingAndReportableSegments" name="NumberOfOperatingAndReportableSegments" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_StateGuarantedLoanMember" name="StateGuarantedLoanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ClassesOfCommitmentsDomain" name="ClassesOfCommitmentsDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FixturesFittingsAndOtherEquipmentMember" name="FixturesFittingsAndOtherEquipmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_OtherProvisionForChargesOtherComprehensiveIncome" name="OtherProvisionForChargesOtherComprehensiveIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_RevenueFromCollaborationAgreements" name="RevenueFromCollaborationAgreements" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_MajorShareholdersAxis" name="MajorShareholdersAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreasrDecreaseInNetFinancialGainLoss" name="IncreasrDecreaseInNetFinancialGainLoss" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_OtherNonCurrentFinancialLiabilitiesMember" name="OtherNonCurrentFinancialLiabilitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CommercialLitigationsAdditions" name="CommercialLitigationsAdditions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_OtherCurrentAssetsAbstract" name="OtherCurrentAssetsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_ProvisionsForTerminationBenefitsNoncurrentProvisions" name="ProvisionsForTerminationBenefitsNoncurrentProvisions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_BorrowingExtendedPeriod" name="BorrowingExtendedPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ContractualCommitments" name="ContractualCommitments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncomeLossMember" name="IncomeLossMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_PercentageOfFinancingTaxReceivableRelatedToResearchTaxCredit" name="PercentageOfFinancingTaxReceivableRelatedToResearchTaxCredit" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfDetailedInformationAboutOtherCurrentLiabilitiesExplanatory" name="DisclosureOfDetailedInformationAboutOtherCurrentLiabilitiesExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_ClassOfWarrantsOrRightAxis" name="ClassOfWarrantsOrRightAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_IncreaseDecreaseInForeignExchangeLosses" name="IncreaseDecreaseInForeignExchangeLosses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTaxFromContinuingOperations" name="OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTaxFromContinuingOperations" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NonCurrentProvisionsOtherComprehensiveIncome" name="NonCurrentProvisionsOtherComprehensiveIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfFinancialAssetsAndLiabilitiesLineItems" name="DisclosureOfFinancialAssetsAndLiabilitiesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_PensionMember" name="PensionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_FairValuesPerOptions" name="FairValuesPerOptions" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_ProvisionsForEmployeeLitigationAndSeveranceAmountsUsedDuringThePeriod" name="ProvisionsForEmployeeLitigationAndSeveranceAmountsUsedDuringThePeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_DisclosureOfRevenueLineItems" name="DisclosureOfRevenueLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_CollaborationAgreementAxis" name="CollaborationAgreementAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_MilestonePaymentFor10Candidate" name="MilestonePaymentFor10Candidate" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_NumberOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements" name="NumberOfShareOptionsExercisableGrantedInShareBasedPaymentArrangements" type="xbrli:decimalItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_DisclosureOfBasisOfConsolidationAndMaterialAccountingPolicyInformationExplanatory" name="DisclosureOfBasisOfConsolidationAndMaterialAccountingPolicyInformationExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_CompanySharePrice" name="CompanySharePrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
  <xsd:element id="clls_IncreaseDecreaseThroughFinancingCashFlowsExcludingInterestPaymentsLiabilitiesArisingFromFinancingActivities" name="IncreaseDecreaseThroughFinancingCashFlowsExcludingInterestPaymentsLiabilitiesArisingFromFinancingActivities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_AdditionForCurrentProvision" name="AdditionForCurrentProvision" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeShares" name="IncreaseInNumberOfOrdinarySharesIssuedDueToVestingOfFreeShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_EuropeanInvestmentBankLoanTrancheAMember" name="EuropeanInvestmentBankLoanTrancheAMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_AgreementsExtendedMaturityDate" name="AgreementsExtendedMaturityDate" type="xbrli:dateItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_OtherSubsidiesAmount" name="OtherSubsidiesAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_WeightedAverageSharePriceShareOptionsGrantedPerShare" name="WeightedAverageSharePriceShareOptionsGrantedPerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_MilestonePayment" name="MilestonePayment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_FairValueAtMeasurementDateShareOptionsGrantedPerShare" name="FairValueAtMeasurementDateShareOptionsGrantedPerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_FairValueOfExpectedVolatilityAmountPlusFivePercentage" name="FairValueOfExpectedVolatilityAmountPlusFivePercentage" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="clls_OtherProvisionForChargesAdditions" name="OtherProvisionForChargesAdditions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="clls_CalyxtIncMember" name="CalyxtIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="clls_DescriptionOfAccountingPolicyForGoingConcernExplanatory" name="DescriptionOfAccountingPolicyForGoingConcernExplanatory" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="clls_WarrantsGrantDate" name="WarrantsGrantDate" type="xbrli:dateItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false"/>
</xsd:schema>
