Exhibit 21.1
| Subsidiaries of Galmed Pharmaceuticals Ltd. | Jurisdiction of Incorporation | |
| Colospan Ltd. | Israel | |
| Galmed International Ltd. | Malta | |
| Galmed Research and Development Ltd. | Israel | |
| Galtopa Therapeutics Ltd. | Israel | |
| Galmed Therapeutics UK Limited* | England and Wales | |
| OnKai, Inc.** | Delaware |
* Wholly-owned subsidiary of Galmed Research and Development Ltd.
** Partially-owned subsidiary of Galtopa Therapeutics Ltd.