Segment Information - Schedule of Reportable Segment Revenue, Operating Expenses, and Net Loss (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | 12 Months Ended | |||||
|---|---|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
Dec. 31, 2025 |
Dec. 31, 2024 |
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| Segment Reporting [Line Items] | ||||||||
| Revenue from Contract with Customer, Including Assessed Tax | $ 0 | $ 80,000 | ||||||
| Operating expenses: | ||||||||
| Operating Expenses | $ 29,310 | $ 19,815 | $ 51,496 | $ 40,218 | 84,769 | 101,897 | ||
| General and administrative | 7,462 | 6,828 | 15,564 | 13,827 | 28,666 | 36,448 | ||
| Impairment of long-lived assets | 5,086 | 0 | 5,086 | 0 | ||||
| Restructuring expenses | 4,318 | 0 | 4,318 | 0 | 0 | 2,063 | ||
| Loss from operations | (29,310) | (19,815) | (51,496) | (40,218) | (84,769) | (21,897) | ||
| Other income, net | 3,131 | 2,519 | 6,426 | 5,267 | 9,889 | 12,172 | ||
| Net loss | (26,179) | $ (18,891) | (17,296) | $ (17,655) | (45,070) | (34,951) | (74,880) | (9,725) |
| Operating Segments [Member] | ||||||||
| Segment Reporting [Line Items] | ||||||||
| Revenue from Contract with Customer, Including Assessed Tax | 0 | 80,000 | ||||||
| Operating expenses: | ||||||||
| Operating Expenses | 29,310 | 19,815 | 51,496 | 40,218 | 84,769 | 101,897 | ||
| Employee compensation expenses (excluding stock-based compensation expenses) | 2,085 | 2,808 | 6,085 | 5,887 | 12,659 | 15,347 | ||
| Stock-based compensation expenses | 705 | 555 | 2,076 | 1,539 | 3,448 | 4,653 | ||
| General and administrative | 7,462 | 6,828 | 15,564 | 13,827 | 28,666 | 36,448 | ||
| Impairment of long-lived assets | 5,086 | 0 | 5,086 | 0 | ||||
| Restructuring expenses | 4,318 | 0 | 4,318 | 0 | 0 | 2,063 | ||
| Loss from operations | (29,310) | (19,815) | (51,496) | (40,218) | (84,769) | (21,897) | ||
| Other income, net | 3,131 | 2,519 | 6,426 | 5,267 | 9,889 | 12,172 | ||
| Net loss | (26,179) | (17,296) | (45,070) | (34,951) | (74,880) | (9,725) | ||
| Operating Segments [Member] | Losmapimod | ||||||||
| Operating expenses: | ||||||||
| Operating Expenses | 0 | (89) | 0 | 935 | 941 | 20,801 | ||
| Operating Segments [Member] | Pre-Development Candidate Expenses | ||||||||
| Operating expenses: | ||||||||
| Operating Expenses | 4,488 | 5,620 | 7,787 | 9,673 | 19,061 | 14,008 | ||
| Operating Segments [Member] | Pociredir | ||||||||
| Operating expenses: | ||||||||
| Operating Expenses | $ 5,166 | $ 4,093 | $ 10,580 | $ 8,357 | $ 19,994 | $ 8,577 | ||
| X | ||||||||||
- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of expense for employee benefit and equity-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of impairment loss for long-lived asset held and used. Includes, but is not limited to, impairment loss for long-lived asset to be disposed of other than by sale. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of interest income (expense) classified as nonoperating. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- References No definition available.
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- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Discloses the amount charged against the accrued restructuring reserves, or earnings if not previously accrued, during the period for the specified type of restructuring cost. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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