v3.26.1
Income Taxes - Schedule of Reconciliation of U.S. Federal Statutory Income Tax Rate (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Income Tax Disclosure [Abstract]    
U.S. federal statutory tax rate $ (15,701) $ (1,978)
U.S. federal statutory tax rate 21.00% 21.00%
State and local income tax, net of federal income tax effect $ 0 $ 0
State and local income tax, net of federal income tax effect 0.00% 0.00%
Foreign tax effects $ 0 $ 0
Foreign tax effects 0.00% 0.00%
Effects of changes in tax laws or rates enacted in the current period $ 0 $ 0
Effects of changes in tax laws or rates enacted in the current period 0.00% 0.00%
Effects of cross-border-tax laws $ 0 $ 0
Effects of cross-border-tax laws 0.00% 0.00%
Tax credits:    
Federal research and development credits $ (908) $ (884)
Federal research and development credits 0.01% 0.09%
Federal orphan drug credits $ (5,255) $ (7,297)
Federal orphan drug credits 0.07% 0.77%
Changes in valuation allowances $ 20,716 $ (89,613)
Changes in valuation allowances (0.28%) 9.51%
Nontaxable or nondeductible items:    
Stock-based compensation $ 0 $ 587
Stock-based compensation 0.00% (0.06%)
Officers' compensation $ 879 $ 482
Officers' compensation (0.01%) (0.05%)
Other permanent differences $ (103) $ 85
Other permanent differences 0.00% (0.01%)
Changes in unrecognized tax benefits $ 0 $ 0
Changes in unrecognized tax benefits 0.00% 0.00%
Other adjustments:    
Impact of ownership change $ 0 $ 97,547
Impact of ownership change 0.00% (10.36%)
Stock compensation cancellations $ 0 $ 1,322
Stock compensation cancellations 0.00% (0.14%)
Other $ 372 $ (251)
Other 0.00% 0.03%
Effective income tax rate $ 0 $ 0
Effective income tax rate 0.00% 0.00%