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- Definition

Development regulatory and commercial milestones.

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- Definition

Future commercial milestone payments.

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- Definition

Future development and regulatory milestone payments.

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- Definition

License agreement additional milestone payments.

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- Definition

Milestone payments.

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- Definition

Research and development milestones receivable.

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- Definition

Amount of expenses incurred but not yet paid nor invoiced, and liabilities classified as other.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of deferred income and obligation to transfer product and service to customer for which consideration has been received or is receivable, classified as current.

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Amount of deferred income and obligation to transfer product and service to customer for which consideration has been received or is receivable, classified as noncurrent.

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- Definition

The amount of cash paid for royalties during the current period.

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- Definition

Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Collaboration and License Agreements - Additional Information (Details) - USD ($)	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025	Dec. 31, 2025
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expenses	$ 8,823,000	$ 13,884,000	$ 20,128,000	$ 29,876,000
Accrued and other current liabilities	7,183,000		7,183,000		$ 6,405,000
Revenue	1,918,000	4,898,000	4,151,000	22,023,000
Short-term deferred revenue	27,475,000		27,475,000		21,087,000
Long-term deferred revenue	11,698,000		11,698,000		19,936,000
Regents Exclusive License Agreements
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Future development and regulatory milestone payments	27,700,000		27,700,000
Future commercial milestone payments	3,600,000		3,600,000
Research and development expenses		400,000	400,000	400,000
Milestones			0		0
Accrued and other current liabilities	100,000		100,000
Royalties			0		0
Regents Exclusive License Agreements \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expenses	100,000
Acuitas Agreements
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Future development and regulatory milestone payments	20,000,000		20,000,000
Future commercial milestone payments	40,000,000		40,000,000
Research and development expenses	2,000,000	100,000		500,000
Milestones			0		0
Accrued and other current liabilities	2,100,000		2,100,000
Acuitas Agreements \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expenses			2,000,000
Prevail License Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expenses			31,000,000		31,000,000
Revenue	1,900,000	4,800,000	4,200,000	21,600,000
Short-term deferred revenue	10,600,000		10,600,000
Additional milestones			0		0
Prevail License Agreement \| Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development milestones receivable	110,000,000		110,000,000
Commercial milestones receivable	1,100,000,000		1,100,000,000
Sanofi Agreements
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	0	120,000	0	455,000
Sanofi Agreements \| 2022 License Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	0	0	0	0
Development regulatory and commercial milestones	0		0		$ 0
Sanofi Agreements \| 2023 License Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones	0	0	0	0
Revenue	0	$ 100,000	0	$ 500,000
Short-term deferred revenue	16,800,000		16,800,000
Long-term deferred revenue	$ 11,700,000		$ 11,700,000