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<inf:proxyVoteTable xmlns:inf="http://www.sec.gov/edgar/document/npxproxy/informationtable">
  <inf:proxyTable>
    <inf:issuerName>BICYCLE THERAPEUTICS PLC</inf:issuerName>
    <inf:cusip>088786108</inf:cusip>
    <inf:meetingDate>6/17/2026</inf:meetingDate>
    <inf:voteDescription>To approve, on advisory basis, the compensation of our named executive officers, as disclosed in this proxy statement.</inf:voteDescription>
    <inf:voteCategories>
      <inf:voteCategory>
        <inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType>
      </inf:voteCategory>
    </inf:voteCategories>
    <inf:voteSource>ISSUER</inf:voteSource>
    <inf:sharesVoted>3468430</inf:sharesVoted>
    <inf:sharesOnLoan>0</inf:sharesOnLoan>
    <inf:vote>
      <inf:voteRecord>
        <inf:howVoted>FOR</inf:howVoted>
        <inf:sharesVoted>3468430</inf:sharesVoted>
        <inf:managementRecommendation>FOR</inf:managementRecommendation>
      </inf:voteRecord>
    </inf:vote>
  </inf:proxyTable>
  <inf:proxyTable>
    <inf:issuerName>CRESCENT BIOPHARMA INC.</inf:issuerName>
    <inf:cusip>G2545C104</inf:cusip>
    <inf:meetingDate>6/2/2026</inf:meetingDate>
    <inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation for our named executive officers.</inf:voteDescription>
    <inf:voteCategories>
      <inf:voteCategory>
        <inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType>
      </inf:voteCategory>
    </inf:voteCategories>
    <inf:voteSource>ISSUER</inf:voteSource>
    <inf:sharesVoted>1677852</inf:sharesVoted>
    <inf:sharesOnLoan>0</inf:sharesOnLoan>
    <inf:vote>
      <inf:voteRecord>
        <inf:howVoted>FOR</inf:howVoted>
        <inf:sharesVoted>1677852</inf:sharesVoted>
        <inf:managementRecommendation>FOR</inf:managementRecommendation>
      </inf:voteRecord>
    </inf:vote>
  </inf:proxyTable>
  <inf:proxyTable>
    <inf:issuerName>CRESCENT BIOPHARMA INC.</inf:issuerName>
    <inf:cusip>G2545C104</inf:cusip>
    <inf:meetingDate>6/2/2026</inf:meetingDate>
    <inf:voteDescription>To approve, on a non-binding, advisory basis, the frequency of future advisory votes to approve the compensation for our named executive officers.</inf:voteDescription>
    <inf:voteCategories>
      <inf:voteCategory>
        <inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType>
      </inf:voteCategory>
    </inf:voteCategories>
    <inf:voteSource>ISSUER</inf:voteSource>
    <inf:sharesVoted>1677852</inf:sharesVoted>
    <inf:sharesOnLoan>0</inf:sharesOnLoan>
    <inf:vote>
      <inf:voteRecord>
        <inf:howVoted>FOR</inf:howVoted>
        <inf:sharesVoted>1677852</inf:sharesVoted>
        <inf:managementRecommendation>FOR</inf:managementRecommendation>
      </inf:voteRecord>
    </inf:vote>
  </inf:proxyTable>
  <inf:proxyTable>
    <inf:issuerName>DAMORA THERAPEUTICS INC</inf:issuerName>
    <inf:cusip>36322Q206</inf:cusip>
    <inf:meetingDate>6/17/2026</inf:meetingDate>
    <inf:voteDescription>To approve, on an advisory basis, the compensation paid to our named executive officers;</inf:voteDescription>
    <inf:voteCategories>
      <inf:voteCategory>
        <inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType>
      </inf:voteCategory>
    </inf:voteCategories>
    <inf:voteSource>ISSUER</inf:voteSource>
    <inf:sharesVoted>2441000</inf:sharesVoted>
    <inf:sharesOnLoan>0</inf:sharesOnLoan>
    <inf:vote>
      <inf:voteRecord>
        <inf:howVoted>FOR</inf:howVoted>
        <inf:sharesVoted>2441000</inf:sharesVoted>
        <inf:managementRecommendation>FOR</inf:managementRecommendation>
      </inf:voteRecord>
    </inf:vote>
  </inf:proxyTable>
  <inf:proxyTable>
    <inf:issuerName>DYNE THERAPEUTICS INC</inf:issuerName>
    <inf:cusip>26818M108</inf:cusip>
    <inf:meetingDate>6/5/2026</inf:meetingDate>
    <inf:voteDescription>To vote, on an advisory basis, to approve the compensation of our named executive officers;</inf:voteDescription>
    <inf:voteCategories>
      <inf:voteCategory>
        <inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType>
      </inf:voteCategory>
    </inf:voteCategories>
    <inf:voteSource>ISSUER</inf:voteSource>
    <inf:sharesVoted>4644386</inf:sharesVoted>
    <inf:sharesOnLoan>0</inf:sharesOnLoan>
    <inf:vote>
      <inf:voteRecord>
        <inf:howVoted>FOR</inf:howVoted>
        <inf:sharesVoted>4644386</inf:sharesVoted>
        <inf:managementRecommendation>FOR</inf:managementRecommendation>
      </inf:voteRecord>
    </inf:vote>
    <inf:voteManager>
      <inf:otherManagers>
        <inf:otherManager>2</inf:otherManager>
      </inf:otherManagers>
    </inf:voteManager>
  </inf:proxyTable>
  <inf:proxyTable>
    <inf:issuerName>NEWAMSTERDAM PHARMA COMPANY</inf:issuerName>
    <inf:cusip>N62509109</inf:cusip>
    <inf:meetingDate>6/2/2026</inf:meetingDate>
    <inf:voteDescription>Non-binding, advisory vote to approve the 2025 compensation of named executive officers </inf:voteDescription>
    <inf:voteCategories>
      <inf:voteCategory>
        <inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType>
      </inf:voteCategory>
    </inf:voteCategories>
    <inf:voteSource>ISSUER</inf:voteSource>
    <inf:sharesVoted>9198900</inf:sharesVoted>
    <inf:sharesOnLoan>0</inf:sharesOnLoan>
    <inf:vote>
      <inf:voteRecord>
        <inf:howVoted>FOR</inf:howVoted>
        <inf:sharesVoted>9198900</inf:sharesVoted>
        <inf:managementRecommendation>FOR</inf:managementRecommendation>
      </inf:voteRecord>
    </inf:vote>
    <inf:voteManager>
      <inf:otherManagers>
        <inf:otherManager>1</inf:otherManager>
      </inf:otherManagers>
      <inf:otherManagers>
        <inf:otherManager>2</inf:otherManager>
      </inf:otherManagers>
    </inf:voteManager>
  </inf:proxyTable>
  <inf:proxyTable>
    <inf:issuerName>REPLIMUNE GROUP INC</inf:issuerName>
    <inf:cusip>76029N106</inf:cusip>
    <inf:meetingDate>9/3/2025</inf:meetingDate>
    <inf:voteDescription>To approve, on a non-binding advisory basis, the compensation of the Company&#x2019;s named executive officers for the fiscal year ended March&#xA0;31, 2026</inf:voteDescription>
    <inf:voteCategories>
      <inf:voteCategory>
        <inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType>
      </inf:voteCategory>
    </inf:voteCategories>
    <inf:voteSource>ISSUER</inf:voteSource>
    <inf:sharesVoted>3656753</inf:sharesVoted>
    <inf:sharesOnLoan>0</inf:sharesOnLoan>
    <inf:vote>
      <inf:voteRecord>
        <inf:howVoted>FOR</inf:howVoted>
        <inf:sharesVoted>3656753</inf:sharesVoted>
        <inf:managementRecommendation>FOR</inf:managementRecommendation>
      </inf:voteRecord>
    </inf:vote>
  </inf:proxyTable>
</inf:proxyVoteTable>
